BRPI1008532A2 - "composições, métodos e usos para arcabouço com base no domínio fibronectina tipo iii". - Google Patents
"composições, métodos e usos para arcabouço com base no domínio fibronectina tipo iii".Info
- Publication number
- BRPI1008532A2 BRPI1008532A2 BRPI1008532A BRPI1008532A BRPI1008532A2 BR PI1008532 A2 BRPI1008532 A2 BR PI1008532A2 BR PI1008532 A BRPI1008532 A BR PI1008532A BR PI1008532 A BRPI1008532 A BR PI1008532A BR PI1008532 A2 BRPI1008532 A2 BR PI1008532A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- type iii
- based compositions
- domain type
- fibronectin domain
- Prior art date
Links
- 102000016359 Fibronectins Human genes 0.000 title 1
- 108010067306 Fibronectins Proteins 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1044—Preparation or screening of libraries displayed on scaffold proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
- C40B40/08—Libraries containing RNA or DNA which encodes proteins, e.g. gene libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/06—Biochemical methods, e.g. using enzymes or whole viable microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Neurology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15198709P | 2009-02-12 | 2009-02-12 | |
| US61/151,987 | 2009-02-12 | ||
| PCT/US2010/023625 WO2010093627A2 (en) | 2009-02-12 | 2010-02-09 | Fibronectin type iii domain based scaffold compositions, methods and uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI1008532A2 true BRPI1008532A2 (pt) | 2018-04-03 |
| BRPI1008532B1 BRPI1008532B1 (pt) | 2021-12-14 |
Family
ID=42562254
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1008532-7A BRPI1008532B1 (pt) | 2009-02-12 | 2010-02-09 | Arcabouço de proteína isolada, método para construção de uma biblioteca de arcabouço de proteína isolada, molécula de ácido nucleico isolada, vetor de ácido nucleico isolado, célula hospedeira de bactéria ou fungo, composição, dispositivo médico e artigo de manufatura para uso farmacêutico ou de diagnóstico em seres humanos |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8293482B2 (pt) |
| EP (1) | EP2396011B1 (pt) |
| JP (1) | JP5873335B2 (pt) |
| CN (1) | CN102596992B (pt) |
| AU (1) | AU2010213892B2 (pt) |
| BR (1) | BRPI1008532B1 (pt) |
| CA (1) | CA2752211C (pt) |
| DK (1) | DK2396011T3 (pt) |
| IL (1) | IL214539A (pt) |
| MX (1) | MX2011008566A (pt) |
| RU (1) | RU2562700C2 (pt) |
| WO (1) | WO2010093627A2 (pt) |
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| KR20100128291A (ko) | 2008-02-14 | 2010-12-07 | 브리스톨-마이어스 스큅 컴퍼니 | Ｅｇｆｒ에 결합하는 조작된 단백질을 기초로 하는 표적화된 치료제 |
| CN102099373A (zh) | 2008-05-22 | 2011-06-15 | 百时美施贵宝公司 | 基于纤连蛋白的多价支架结构域蛋白 |
| BRPI0919881B1 (pt) | 2008-10-31 | 2021-09-08 | Centocor Ortho Biotech Inc | Proteína de arcabouço e seu método de geração, biblioteca e seu método de construção, molécula de ácido nucleico, vetor de ácido nucleico, célula hospedeira, composição, dispositivo médico e artigo de fabricação |
| TWI496582B (zh) | 2008-11-24 | 2015-08-21 | 必治妥美雅史谷比公司 | 雙重專一性之ｅｇｆｒ／ｉｇｆｉｒ結合分子 |
| ES2755398T3 (es) | 2010-04-13 | 2020-04-22 | Medimmune Llc | Andamios multiméricos específicos de TRAIL R2 |
| EP3103478B1 (en) | 2010-04-30 | 2019-04-17 | Janssen Biotech, Inc. | Stabilized fibronectin domain compositions, methods and uses |
| TW201138808A (en) | 2010-05-03 | 2011-11-16 | Bristol Myers Squibb Co | Serum albumin binding molecules |
| ES2573108T3 (es) | 2010-05-26 | 2016-06-06 | Bristol-Myers Squibb Company | Proteínas de armazón a base de fibronectina que tienen estabilidad mejorada |
| KR20190089048A (ko) | 2011-02-15 | 2019-07-29 | 이뮤노젠 아이엔씨 | 컨쥬게이트의 제조방법 |
| EP2697257B1 (en) | 2011-04-13 | 2016-10-19 | Bristol-Myers Squibb Company | Fc fusion proteins comprising novel linkers or arrangements |
| EP2710382B1 (en) | 2011-05-17 | 2017-10-18 | Bristol-Myers Squibb Company | Improved methods for the selection of binding proteins |
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-
2010
- 2010-02-09 BR BRPI1008532-7A patent/BRPI1008532B1/pt not_active IP Right Cessation
- 2010-02-09 JP JP2011550185A patent/JP5873335B2/ja not_active Expired - Fee Related
- 2010-02-09 MX MX2011008566A patent/MX2011008566A/es active IP Right Grant
- 2010-02-09 CN CN201080017059.1A patent/CN102596992B/zh not_active Expired - Fee Related
- 2010-02-09 DK DK10741624.0T patent/DK2396011T3/en active
- 2010-02-09 WO PCT/US2010/023625 patent/WO2010093627A2/en not_active Ceased
- 2010-02-09 CA CA2752211A patent/CA2752211C/en active Active
- 2010-02-09 RU RU2011137464/10A patent/RU2562700C2/ru active
- 2010-02-09 EP EP10741624.0A patent/EP2396011B1/en active Active
- 2010-02-09 AU AU2010213892A patent/AU2010213892B2/en not_active Ceased
- 2010-02-12 US US12/704,824 patent/US8293482B2/en active Active
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2011
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|---|---|
| AU2010213892A1 (en) | 2011-09-01 |
| IL214539A (en) | 2015-01-29 |
| CA2752211C (en) | 2020-03-24 |
| DK2396011T3 (en) | 2016-04-25 |
| JP2012517240A (ja) | 2012-08-02 |
| RU2011137464A (ru) | 2013-03-20 |
| EP2396011A2 (en) | 2011-12-21 |
| BRPI1008532B1 (pt) | 2021-12-14 |
| WO2010093627A3 (en) | 2010-10-14 |
| IL214539A0 (en) | 2011-09-27 |
| EP2396011B1 (en) | 2016-04-13 |
| WO2010093627A2 (en) | 2010-08-19 |
| EP2396011A4 (en) | 2012-10-24 |
| AU2010213892B2 (en) | 2014-10-23 |
| RU2562700C2 (ru) | 2015-09-10 |
| CN102596992B (zh) | 2015-09-09 |
| MX2011008566A (es) | 2011-11-29 |
| CN102596992A (zh) | 2012-07-18 |
| US20100255056A1 (en) | 2010-10-07 |
| CA2752211A1 (en) | 2010-08-19 |
| US8293482B2 (en) | 2012-10-23 |
| JP5873335B2 (ja) | 2016-03-01 |
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