CA1192496A - Composes pharmaceutiques a usage topique - Google Patents

Composes pharmaceutiques a usage topique

Info

Publication number
CA1192496A
CA1192496A CA000400470A CA400470A CA1192496A CA 1192496 A CA1192496 A CA 1192496A CA 000400470 A CA000400470 A CA 000400470A CA 400470 A CA400470 A CA 400470A CA 1192496 A CA1192496 A CA 1192496A
Authority
CA
Canada
Prior art keywords
composition
skin
active agent
ester
emulsifier
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000400470A
Other languages
English (en)
Inventor
Joachim Franz
Jochen Ziegenmeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH2327/81A external-priority patent/CH653256A5/de
Priority claimed from CH2631/81A external-priority patent/CH647149A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1192496A publication Critical patent/CA1192496A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000400470A 1981-04-06 1982-04-05 Composes pharmaceutiques a usage topique Expired CA1192496A (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH2327/81 1981-04-06
CH2327/81A CH653256A5 (en) 1981-04-06 1981-04-06 Microemulsion for cutaneous use
CH2631/81A CH647149A5 (en) 1981-04-22 1981-04-22 Composition with 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole for cutaneous use
CH2631/81 1981-04-22
CH327881 1981-05-20
CH3278/81 1981-05-20

Publications (1)

Publication Number Publication Date
CA1192496A true CA1192496A (fr) 1985-08-27

Family

ID=27173625

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000400470A Expired CA1192496A (fr) 1981-04-06 1982-04-05 Composes pharmaceutiques a usage topique

Country Status (16)

Country Link
AU (1) AU564570B2 (fr)
CA (1) CA1192496A (fr)
DE (1) DE3212053A1 (fr)
DK (1) DK155882A (fr)
ES (1) ES8308698A1 (fr)
FI (1) FI821123A7 (fr)
FR (1) FR2502951B1 (fr)
GB (2) GB2098865B (fr)
GR (1) GR75462B (fr)
IL (1) IL65424A0 (fr)
IT (1) IT8220611A0 (fr)
MY (1) MY8600571A (fr)
NL (1) NL8201413A (fr)
NZ (1) NZ200232A (fr)
PT (1) PT74703B (fr)
SE (1) SE8202172L (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39128E1 (en) 1997-10-29 2006-06-13 Smithkline Beecham P.L.C. Pleuromutilin derivatives as antimicrobials
US20100081669A1 (en) * 2008-10-01 2010-04-01 Taiwan Biotech Co., Ltd. Pressure sensitive adhesive matrix device or system for the treatment or prevention of onychomycosis or tinea pedis

Families Citing this family (68)

* Cited by examiner, † Cited by third party
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CH655656B (fr) * 1982-10-07 1986-05-15
CA1225594A (fr) * 1983-05-20 1987-08-18 Jourge Heller Methode pour l'administration percutanee d'agents actifs
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung
JPH0667835B2 (ja) * 1984-03-01 1994-08-31 サンド・アクチエンゲゼルシヤフト 医薬組成物
US5364628A (en) * 1985-05-31 1994-11-15 Sandoz Ltd. Pharmaceutical compositions
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
JPS61280426A (ja) * 1985-06-04 1986-12-11 Ikeda Mohandou:Kk 消炎鎮痛用貼付剤
US4767625A (en) * 1985-09-02 1988-08-30 Kao Corporation Lamella type single phase liquid crystal composition and oil-base cosmetic compositions using the same
US4690774A (en) 1985-09-11 1987-09-01 Chesebrough Pond's Inc. Novel translucent water in oil emulsions
US4797272A (en) * 1985-11-15 1989-01-10 Eli Lilly And Company Water-in-oil microemulsions for cosmetic uses
DE3805744C2 (de) * 1987-03-04 1999-09-23 Novartis Ag Phenylcarbamate zur Hemmung der Acetylcholinesterase
IL88076A (en) * 1987-10-28 1993-01-14 Nippon Shinyaku Co Ltd Fat emulsions as drug carriers
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
US5342625A (en) * 1988-09-16 1994-08-30 Sandoz Ltd. Pharmaceutical compositions comprising cyclosporins
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
US5241925A (en) * 1988-12-27 1993-09-07 Dermamed Apparatus and techniques for administering veterinary medicaments
US5332577A (en) * 1988-12-27 1994-07-26 Dermamed Transdermal administration to humans and animals
US7081445B2 (en) 1989-02-20 2006-07-25 Novartis Ag Cyclosporin galenic forms
DE3908047A1 (de) * 1989-03-13 1990-09-20 Desitin Arzneimittel Gmbh Hochdisperse pharmazeutische zusammensetzung
US5324521A (en) * 1989-12-18 1994-06-28 Dermamed Systems for transdermal administration of medicaments
US5149719A (en) * 1990-04-27 1992-09-22 Minnesota Mining And Manufacturing Company Composition for transdermal penetration of medicaments
FR2673537B1 (fr) * 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
DE69229779T2 (de) * 1991-04-19 1999-12-23 Lds Technologies, Inc. Konvertierbare mikroemulsionsverbindungen
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
US6005001A (en) * 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
GB9111611D0 (en) 1991-05-30 1991-07-24 Sandoz Ltd Liposomes
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
GB9126209D0 (en) * 1991-12-10 1992-02-12 Orion Yhtymae Oy Drug formulations for parenteral use
WO1993011798A1 (fr) * 1991-12-16 1993-06-24 Alza Corporation Formulations ameliorees avec agent d'amelioration de la penetration hydrophobe
US5629019A (en) * 1992-02-27 1997-05-13 Alza Corporation Formulations with hydrophobic permeation enhancers
SG45449A1 (en) 1992-05-13 1998-01-16 Sandoz Ltd Ophthalmic compositions
DK0589843T3 (da) 1992-09-25 2002-04-02 Novartis Ag Cyclosporinholdige farmaceutiske præparater
JPH08505367A (ja) * 1992-10-16 1996-06-11 スミスクライン・ビーチャム・コーポレイション 医薬用エマルジョン組成物
JPH08507065A (ja) * 1993-02-17 1996-07-30 スミスクライン・ビーチャム・コーポレイション 医薬組成物含有のミクロエマルジョン
ATE218359T1 (de) 1994-11-03 2002-06-15 Novartis Erfind Verwalt Gmbh Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
DE4442999A1 (de) 1994-12-02 1996-06-05 Hexal Pharma Gmbh Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
US5958876A (en) * 1996-06-19 1999-09-28 Novartis Ag Cyclosporin-containing pharmaceutical compositions
PT988046E (pt) 1997-01-30 2004-12-31 Novartis Ag Composicoes farmaceuticas sem oleo contendo ciclosporina a
IN188719B (fr) * 1997-09-08 2002-11-02 Panacea Biotec Ltd
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6391282B1 (en) * 1997-11-10 2002-05-21 Flemington Pharmaceutical Corp. Antihistamine sprays and ointments for relief of delayed contact dermatitis
DE19825856A1 (de) * 1998-06-10 1999-12-16 Labtec Gmbh Topische Arzneimittelzubereitung
KR100602725B1 (ko) 1998-12-11 2006-07-20 파마솔루션스, 인코포레이티드 물에서 불충분하게 용해되는 약제를 위한 자가-유화용조성물
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US7374779B2 (en) * 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US7244703B2 (en) 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
EP1644004A4 (fr) * 2003-06-20 2010-10-06 Ronald Aung-Din Therapie locale pour le traitement des migraines, des claquages musculaires, des spasmes musculaires, de la spasticite et d'etats apparentes
JP2007513199A (ja) 2003-12-08 2007-05-24 ベントレー ファーマスーティカルス，インコーポレイテッド インスリン治療のための薬学的組成物及び方法
US20060078580A1 (en) 2004-10-08 2006-04-13 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US7740875B2 (en) 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
WO2016033549A2 (fr) 2014-08-28 2016-03-03 Lipocine Inc. Compositions de (17-ss)-3-oxoandrost-4-èn-17-yl tridécanoate et leurs procédés de préparation et d'utilisation
WO2016205423A2 (fr) 2015-06-15 2016-12-22 Lipocine Inc. Composition et méthode pour l'administration orale de promédicaments androgènes
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017173044A1 (fr) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Compositions d'hormones stéroïdes dans des huiles à chaîne moyenne
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
CA3078723A1 (fr) 2016-11-28 2018-05-31 Nachiappan Chidambaram Traitement oral a base d'undecanoate de testosterone
EP3824296B1 (fr) 2018-07-20 2026-04-01 Lipocine Inc. Composition pharmaceutique orale comprenant du tridécanoate de testostérone et/ou du dodécanoate de testostérone pour le traitement des maladies du foie

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH570401A5 (fr) * 1972-05-09 1975-12-15 Wander Ag Dr A
GB1559811A (en) * 1975-07-28 1980-01-30 Sandoz Ltd Pharmaceutically active benzothiadiazole derivatives
CH632268A5 (de) * 1977-01-14 1982-09-30 Sandoz Ag Verfahren zur herstellung von neuen heterocyclylaminoderivaten.

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39128E1 (en) 1997-10-29 2006-06-13 Smithkline Beecham P.L.C. Pleuromutilin derivatives as antimicrobials
USRE43390E1 (en) 1997-10-29 2012-05-15 Glaxosmithkline Llc Pleuromutilin derivatives as antimicrobials
US20100081669A1 (en) * 2008-10-01 2010-04-01 Taiwan Biotech Co., Ltd. Pressure sensitive adhesive matrix device or system for the treatment or prevention of onychomycosis or tinea pedis
US9308203B2 (en) * 2008-10-01 2016-04-12 Taiwan Biotech Co., Ltd. Pressure sensitive adhesive matrix device or system for the treatment or prevention of onychomycosis or tinea pedis

Also Published As

Publication number Publication date
GB2098865A (en) 1982-12-01
IL65424A0 (en) 1982-07-30
NL8201413A (nl) 1982-11-01
FI821123L (fi) 1982-10-07
FR2502951B1 (fr) 1985-12-06
DE3212053A1 (de) 1982-10-21
PT74703B (en) 1984-05-30
GB2148711A (en) 1985-06-05
MY8600571A (en) 1986-12-31
ES511169A0 (es) 1983-10-01
FR2502951A1 (fr) 1982-10-08
PT74703A (en) 1982-05-01
GB8408654D0 (en) 1984-05-16
AU564570B2 (en) 1987-08-20
GB2098865B (en) 1985-12-18
GR75462B (fr) 1984-07-20
ES8308698A1 (es) 1983-10-01
GB2148711B (en) 1985-12-18
IT8220611A0 (it) 1982-04-06
DK155882A (da) 1982-12-10
NZ200232A (en) 1985-08-16
FI821123A0 (fi) 1982-03-31
FI821123A7 (fi) 1982-10-07
AU8233482A (en) 1982-10-14
SE8202172L (sv) 1982-10-07

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Legal Events

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