CH438344A - Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen - Google Patents

Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen

Info

Publication number
CH438344A
CH438344A CH247764A CH247764A CH438344A CH 438344 A CH438344 A CH 438344A CH 247764 A CH247764 A CH 247764A CH 247764 A CH247764 A CH 247764A CH 438344 A CH438344 A CH 438344A
Authority
CH
Switzerland
Prior art keywords
pyrimidines
preparation
basic substituted
substituted pyrimido
pyrimido
Prior art date
Application number
CH247764A
Other languages
English (en)
Inventor
Scheffler Heinz
Josef Dr Roch
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of CH438344A publication Critical patent/CH438344A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH247764A 1963-03-09 1964-02-28 Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen CH438344A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DET0023605 1963-03-09

Publications (1)

Publication Number Publication Date
CH438344A true CH438344A (de) 1967-06-30

Family

ID=7551073

Family Applications (1)

Application Number Title Priority Date Filing Date
CH247764A CH438344A (de) 1963-03-09 1964-02-28 Verfahren zur Herstellung von basisch substituierten Pyrimido (5,4-d)-pyrimidinen

Country Status (5)

Country Link
CH (1) CH438344A (de)
DE (1) DE1470341C3 (de)
FR (1) FR3713M (de)
GB (1) GB1051218A (de)
IT (1) IT7950418A0 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081471A1 (de) * 1970-01-30 1971-12-03 Thomae Gmbh Dr K

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3049207A1 (de) * 1980-12-27 1982-07-29 Dr. Karl Thomae Gmbh, 7950 Biberach Neue trisubstituierte pyrimido (5,4-d) pyrimidine, ihre herstellung und ihre verwendung als arzneimittel
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
RU2005136383A (ru) 2003-04-24 2007-06-10 БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE) Применение дипиридамола или мопидамола для лечения и предупреждения тромбоэмболических заболеваний и нарушений, вызываемыхизбыточным образованием и/или повышенным уровнем экспрессии тромбиновых рецепторов
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2321341B1 (de) 2008-07-16 2017-02-22 Synergy Pharmaceuticals Inc. Zur behandlung von erkrankungen des magen-darm-trakts, entzündlichen erkrankungen, krebs und anderen erkrankungen geeignete agonisten von guanylatcyclase
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EA201391254A1 (ru) 2011-03-01 2014-02-28 Синерджи Фармасьютикалз Инк. Способ получения агонистов гуанилатциклазы c
JP6499591B2 (ja) 2013-02-25 2019-04-10 シナジー ファーマシューティカルズ インコーポレイテッド 結腸洗浄において用いるためのグアニル酸シクラーゼ受容体アゴニスト
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016514671A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼのアゴニストおよびその使用
CN105764916B (zh) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
EP3492106B1 (de) 2013-08-09 2021-02-17 Ardelyx, Inc. Verbindungen und verfahren zur hemmung eines phosphattransports
EP3972599B1 (de) 2019-05-21 2025-10-22 Ardelyx, Inc. Kombination zur senkung des serum-phosphatspiegels bei einem patienten
US12037346B2 (en) 2021-04-13 2024-07-16 Nuvalent, Inc. Amino-substituted heteroaryls for treating cancers with EGFR mutations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081471A1 (de) * 1970-01-30 1971-12-03 Thomae Gmbh Dr K

Also Published As

Publication number Publication date
DE1470341C3 (de) 1974-07-04
DE1470341B2 (de) 1973-12-06
FR3713M (fr) 1965-11-29
DE1470341A1 (de) 1969-07-03
IT7950418A0 (it) 1979-10-01
GB1051218A (de)

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