CL2008003222A1 - Peptidos con actividad antagonista de glucagon y composicion farmaceutica que los comprende, utiles para el tratamiento de la hiperglicemia, para suprimir el apetito, reducir el aumento de peso y para tratar el desgaste catabolico. - Google Patents

Peptidos con actividad antagonista de glucagon y composicion farmaceutica que los comprende, utiles para el tratamiento de la hiperglicemia, para suprimir el apetito, reducir el aumento de peso y para tratar el desgaste catabolico.

Info

Publication number: CL2008003222A1
Authority: CL; Chile
Prior art keywords: pharmaceutical composition; hyperglycemia; peptides; useful; treatment
Prior art date: 2007-10-30

Application number

CL2008003222A

Other languages

English (en)

Spanish (es)

Inventor

Dimarchi Richard

Original Assignee

Univ Indiana Res & Tech Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-10-30

Filing date

2008-10-29

Publication date

2009-02-27

2008-10-29 Application filed by Univ Indiana Res & Tech Corp filed Critical Univ Indiana Res & Tech Corp

2009-02-27 Publication of CL2008003222A1 publication Critical patent/CL2008003222A1/es

Links

239000005557 antagonist Substances 0.000 title abstract 5
108060003199 Glucagon Proteins 0.000 title abstract 4
MASNOZXLGMXCHN-ZLPAWPGGSA-N glucagon Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 MASNOZXLGMXCHN-ZLPAWPGGSA-N 0.000 title abstract 4
229960004666 glucagon Drugs 0.000 title abstract 4
201000001421 hyperglycemia Diseases 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
102400000321 Glucagon Human genes 0.000 title 1
230000036528 appetite Effects 0.000 title 1
235000019789 appetite Nutrition 0.000 title 1
230000001925 catabolic effect Effects 0.000 title 1
230000000694 effects Effects 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
230000004584 weight gain Effects 0.000 title 1
235000019786 weight gain Nutrition 0.000 title 1
102000051325 Glucagon Human genes 0.000 abstract 3
239000000539 dimer Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Obesity (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Toxicology (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Child & Adolescent Psychology (AREA)
Emergency Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

CL2008003222A 2007-10-30 2008-10-29 Peptidos con actividad antagonista de glucagon y composicion farmaceutica que los comprende, utiles para el tratamiento de la hiperglicemia, para suprimir el apetito, reducir el aumento de peso y para tratar el desgaste catabolico. CL2008003222A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US98378307P	2007-10-30	2007-10-30

Publications (1)

Publication Number	Publication Date
CL2008003222A1 true CL2008003222A1 (es)	2009-02-27

Family

ID=40591715

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CL2008003222A CL2008003222A1 (es)	2007-10-30	2008-10-29	Peptidos con actividad antagonista de glucagon y composicion farmaceutica que los comprende, utiles para el tratamiento de la hiperglicemia, para suprimir el apetito, reducir el aumento de peso y para tratar el desgaste catabolico.

Country Status (12)

Country	Link
US (1)	US8981047B2 (2)
EP (1)	EP2217701B9 (2)
JP (1)	JP5669582B2 (2)
AR (1)	AR069110A1 (2)
AU (1)	AU2008318986B2 (2)
CA (1)	CA2707861A1 (2)
CL (1)	CL2008003222A1 (2)
ES (1)	ES2509883T3 (2)
MX (1)	MX2010004297A (2)
PE (1)	PE20091393A1 (2)
TW (1)	TW200920404A (2)
WO (1)	WO2009058662A2 (2)

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2008
- 2008-10-23 WO PCT/US2008/080973 patent/WO2009058662A2/en not_active Ceased
- 2008-10-23 JP JP2010532154A patent/JP5669582B2/ja not_active Expired - Fee Related
- 2008-10-23 ES ES08845852.6T patent/ES2509883T3/es active Active
- 2008-10-23 US US12/739,342 patent/US8981047B2/en not_active Expired - Fee Related
- 2008-10-23 MX MX2010004297A patent/MX2010004297A/es active IP Right Grant
- 2008-10-23 EP EP08845852.6A patent/EP2217701B9/en not_active Not-in-force
- 2008-10-23 AU AU2008318986A patent/AU2008318986B2/en not_active Ceased
- 2008-10-23 CA CA2707861A patent/CA2707861A1/en not_active Abandoned
- 2008-10-29 AR ARP080104739A patent/AR069110A1/es unknown
- 2008-10-29 CL CL2008003222A patent/CL2008003222A1/es unknown
- 2008-10-30 TW TW097141806A patent/TW200920404A/zh unknown
- 2008-10-30 PE PE2008001856A patent/PE20091393A1/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
AU2008318986B2 (en)	2014-12-04
EP2217701A4 (en)	2011-06-15
US8981047B2 (en)	2015-03-17
US20120122783A1 (en)	2012-05-17
AR069110A1 (es)	2009-12-30
PE20091393A1 (es)	2009-09-11
EP2217701B1 (en)	2014-07-02
EP2217701B9 (en)	2015-02-18
AU2008318986A1 (en)	2009-05-07
JP2011502155A (ja)	2011-01-20
HK1143994A1 (en)	2011-01-21
WO2009058662A2 (en)	2009-05-07
JP5669582B2 (ja)	2015-02-12
ES2509883T3 (es)	2014-10-20
MX2010004297A (es)	2010-05-03
EP2217701A2 (en)	2010-08-18
WO2009058662A3 (en)	2010-01-07
CA2707861A1 (en)	2009-05-07
TW200920404A (en)	2009-05-16

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