CL2011000729A1 - Compuestos derivados de metanopirazolo[3,4-e][1,3]diazepin; procedimiento de preparacion; composicion farmaceutica que los comprende; y su uso en el tratamiento de infecciones bacterianas. - Google Patents

Compuestos derivados de metanopirazolo[3,4-e][1,3]diazepin; procedimiento de preparacion; composicion farmaceutica que los comprende; y su uso en el tratamiento de infecciones bacterianas.

Info

Publication number
CL2011000729A1
CL2011000729A1 CL2011000729A CL2011000729A CL2011000729A1 CL 2011000729 A1 CL2011000729 A1 CL 2011000729A1 CL 2011000729 A CL2011000729 A CL 2011000729A CL 2011000729 A CL2011000729 A CL 2011000729A CL 2011000729 A1 CL2011000729 A1 CL 2011000729A1
Authority
CL
Chile
Prior art keywords
treatment
pharmaceutical composition
methanopyrazolo
diazepine
bacterial infections
Prior art date
Application number
CL2011000729A
Other languages
English (en)
Inventor
Lampilas Maxime
Ledoussal Benoit
Gourdel Marie-Edith
Renaud Emilie
Kebsi Adel
Rowlands David
Pierres Camille
Original Assignee
Novexel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40548019&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011000729(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novexel filed Critical Novexel
Publication of CL2011000729A1 publication Critical patent/CL2011000729A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Compuestos heterocíclicos nitrogenados; procedimiento de preparación; composición farmacéutica; y uso en el tratamiento de infecciones bacterianas.
CL2011000729A 2008-10-03 2011-04-01 Compuestos derivados de metanopirazolo[3,4-e][1,3]diazepin; procedimiento de preparacion; composicion farmaceutica que los comprende; y su uso en el tratamiento de infecciones bacterianas. CL2011000729A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0805472A FR2936798B1 (fr) 2008-10-03 2008-10-03 Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens.

Publications (1)

Publication Number Publication Date
CL2011000729A1 true CL2011000729A1 (es) 2012-07-06

Family

ID=40548019

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2011000729A CL2011000729A1 (es) 2008-10-03 2011-04-01 Compuestos derivados de metanopirazolo[3,4-e][1,3]diazepin; procedimiento de preparacion; composicion farmaceutica que los comprende; y su uso en el tratamiento de infecciones bacterianas.

Country Status (18)

Country Link
US (1) US8067435B2 (es)
EP (2) EP2344499A1 (es)
JP (1) JP5555240B2 (es)
KR (1) KR20110067137A (es)
CN (1) CN102203094B (es)
AU (1) AU2009299511A1 (es)
BR (1) BRPI0919810A8 (es)
CA (1) CA2739503A1 (es)
CL (1) CL2011000729A1 (es)
CO (1) CO6361957A2 (es)
EA (1) EA021799B1 (es)
EC (1) ECSP11010946A (es)
FR (1) FR2936798B1 (es)
IL (1) IL212059A0 (es)
MX (1) MX2011003573A (es)
PE (1) PE20110845A1 (es)
WO (1) WO2010038115A1 (es)
ZA (1) ZA201102429B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8772490B2 (en) 2010-12-22 2014-07-08 Meiji Seika Pharma Co., Ltd. Optically active diazabicyclooctane derivatives and process for preparing the same
KR101618424B1 (ko) 2011-08-30 2016-05-04 욱크하르트 리미티드 1,6-디아자비시클로[3,2,1]옥탄-7-온 유도체 및 세균 감염 치료에서의 그 유도체의 용도
BR112014003476A2 (pt) * 2011-09-13 2017-03-01 Wockhardt Ltd compostos contendo nitrogênio e seu uso
MX2014011825A (es) * 2012-03-30 2015-02-20 Cubist Pharm Inc INHIBIDORES DE ISOXAZOL ß-LACTAMASA.
AR090539A1 (es) 2012-04-02 2014-11-19 Astrazeneca Ab COMPUESTOS INHIBIDORES DE b LACTAMASA
AR091222A1 (es) 2012-05-30 2015-01-21 Meiji Seika Pharma Co Ltd INHIBIDOR DE b-LACTAMASA Y PROCESO PARA PREPARARLO
CA2881169C (en) * 2012-08-25 2020-06-16 Wockhardt Limited 1,6-diazabicyclo [3,2,1]octan - 7 - one derivatives and their use in the treatment of bacterial infections
KR102239725B1 (ko) 2013-09-24 2021-04-12 메이지 세이카 파루마 가부시키가이샤 디아자비시클로옥탄 유도체의 제조법과 그의 중간체
MY199066A (en) 2013-10-08 2023-10-12 Meiji Seika Pharma Co Ltd Processes for producing diazabicyclooctane compounds
EP3055311B1 (en) * 2013-10-11 2017-08-09 Wockhardt Limited Nitrogen containing compounds and their use
BR112017010132B1 (pt) 2014-11-17 2023-02-14 Entasis Therapeutics Limited Combinações e seus usos no tratamento de infecções bacterianas resistentes
BR112017010445B8 (pt) 2014-12-05 2024-02-27 Meiji Seika Pharma Co Ltd Processo de produção de cristais de derivado de diazabiciclo-octano e preparação liofilizada estável
WO2016156348A1 (en) 2015-03-31 2016-10-06 Mutabilis Novel heterocyclic compounds and their use in preventing or treating bacterial infections
EP3075733A1 (en) * 2015-03-31 2016-10-05 Mutabilis Novel heterocyclic compounds and their use in preventing or treating bacterial infections
RU2714197C2 (ru) 2015-04-03 2020-02-13 Мутабилис Гетероциклические соединения и их применение для предупреждения или лечения бактериальных инфекций
CA3000087A1 (en) 2015-10-02 2017-04-06 Legochem Biosciences, Inc. Compositions and methods for inhibiting beta-lactamase
CA3036557A1 (en) 2016-09-16 2018-03-22 Entasis Therapeutics Limited Beta-lactamase inhibitor compounds
PL3630111T3 (pl) 2017-05-08 2022-05-23 Entasis Therapeutics, Inc. Związki i sposoby leczenia zakażeń bakteryjnych
EP3604315A1 (en) 2018-07-30 2020-02-05 Mutabilis Heterocyclic compounds and their use in preventing or treating bacterial infections
CN119998293A (zh) * 2023-08-08 2025-05-13 成都四面体药物研究有限公司 一种含脲三环的β-内酰胺酶抑制剂、其制备方法及其用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387928B1 (en) * 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
ES2321042T3 (es) * 1997-09-15 2009-06-01 THE PROCTER & GAMBLE COMPANY Quinolonas antimicrobianas, composiciones y usos de las mismas.
FR2812635B1 (fr) 2000-08-01 2002-10-11 Aventis Pharma Sa Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
NZ525571A (en) * 2000-12-14 2004-09-24 Procter & Gamble Antimicrobial quinolones
JP2004515549A (ja) * 2000-12-14 2004-05-27 ザ プロクター アンド ギャンブル カンパニー 抗微生物２−ピリドン類、その組成物と使用
FR2825705B1 (fr) * 2001-06-08 2005-05-20 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
FR2835186B1 (fr) * 2002-01-28 2006-10-20 Aventis Pharma Sa Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
US6900224B2 (en) * 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
FR2844273B1 (fr) 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
FR2844270B1 (fr) * 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
FR2844268B1 (fr) * 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
FR2848210B1 (fr) * 2002-12-06 2007-10-19 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
US7232833B2 (en) * 2003-03-28 2007-06-19 Novexel 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
US7449481B2 (en) * 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
FR2914923B1 (fr) * 2007-04-12 2013-06-14 Novexel Nouveaux composes heterocycliques azotes,leur preparation et leur utilisation comme medicaments antibacteriens.
FR2937034B1 (fr) * 2008-10-10 2012-11-23 Novexel Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens

Also Published As

Publication number Publication date
JP2012504593A (ja) 2012-02-23
EP2344499A1 (fr) 2011-07-20
FR2936798A1 (fr) 2010-04-09
CO6361957A2 (es) 2012-01-20
EP2845855A1 (fr) 2015-03-11
CN102203094A (zh) 2011-09-28
FR2936798B1 (fr) 2012-09-28
JP5555240B2 (ja) 2014-07-23
WO2010038115A1 (fr) 2010-04-08
ZA201102429B (en) 2012-05-30
US20100087648A1 (en) 2010-04-08
BRPI0919810A8 (pt) 2017-12-12
BRPI0919810A2 (pt) 2017-10-31
KR20110067137A (ko) 2011-06-21
CN102203094B (zh) 2014-04-02
PE20110845A1 (es) 2011-11-17
EA021799B1 (ru) 2015-09-30
MX2011003573A (es) 2011-08-12
AU2009299511A1 (en) 2010-04-08
ECSP11010946A (es) 2011-05-31
EA201170522A1 (ru) 2011-12-30
IL212059A0 (en) 2011-06-30
CA2739503A1 (fr) 2010-04-08
US8067435B2 (en) 2011-11-29

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