CY1734A - Pharmaceutical capsules containing ranitidine - Google Patents

Pharmaceutical capsules containing ranitidine Download PDF

Info

Publication number: CY1734A
Authority: CY; Cyprus
Prior art keywords: filling; pharmaceutical composition; ranitidine; mixture; oily
Prior art date: 1989-02-23

Application number

CY173494A

Other languages

English (en)

Original Assignee

Glaxo Canada

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-02-23

Filing date

1994-05-06

Publication date

1994-05-06

1994-05-06 Application filed by Glaxo Canada filed Critical Glaxo Canada

1994-05-06 Publication of CY1734A publication Critical patent/CY1734A/en

Links

229960000620 ranitidine Drugs 0.000 title claims description 23
VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 title claims 7
239000002775 capsule Substances 0.000 title description 17
239000000203 mixture Substances 0.000 claims description 31
239000011159 matrix material Substances 0.000 claims description 22
239000007903 gelatin capsule Substances 0.000 claims description 21
235000014113 dietary fatty acids Nutrition 0.000 claims description 17
239000000194 fatty acid Substances 0.000 claims description 17
229930195729 fatty acid Natural products 0.000 claims description 17
150000003839 salts Chemical class 0.000 claims description 17
239000008194 pharmaceutical composition Substances 0.000 claims description 15
239000000546 pharmaceutical excipient Substances 0.000 claims description 15
239000004094 surface-active agent Substances 0.000 claims description 13
108010010803 Gelatin Proteins 0.000 claims description 11
229920000159 gelatin Polymers 0.000 claims description 11
239000008273 gelatin Substances 0.000 claims description 11
235000019322 gelatine Nutrition 0.000 claims description 11
235000011852 gelatine desserts Nutrition 0.000 claims description 11
229960001520 ranitidine hydrochloride Drugs 0.000 claims description 11
GGWBHVILAJZWKJ-KJEVSKRMSA-N ranitidine hydrochloride Chemical compound [H+].[Cl-].[O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 GGWBHVILAJZWKJ-KJEVSKRMSA-N 0.000 claims description 11
239000002480 mineral oil Substances 0.000 claims description 9
150000004665 fatty acids Chemical class 0.000 claims description 7
239000012188 paraffin wax Substances 0.000 claims description 7
239000004480 active ingredient Substances 0.000 claims description 6
239000004615 ingredient Substances 0.000 claims description 6
235000010446 mineral oil Nutrition 0.000 claims description 6
239000012458 free base Substances 0.000 claims description 5
150000003626 triacylglycerols Chemical class 0.000 claims description 5
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical group CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 4
125000005456 glyceride group Chemical group 0.000 claims description 4
235000010445 lecithin Nutrition 0.000 claims description 4
239000000787 lecithin Substances 0.000 claims description 4
229940067606 lecithin Drugs 0.000 claims description 4
239000002687 nonaqueous vehicle Substances 0.000 claims description 2
150000004668 long chain fatty acids Chemical class 0.000 claims 1
150000004667 medium chain fatty acids Chemical class 0.000 claims 1
238000000034 method Methods 0.000 claims 1
VMXUWOKSQNHOCA-UKTHLTGXSA-N ranitidine Chemical compound [O-][N+](=O)\C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-UKTHLTGXSA-N 0.000 description 20
230000002209 hydrophobic effect Effects 0.000 description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
238000009472 formulation Methods 0.000 description 3
239000008240 homogeneous mixture Substances 0.000 description 3
239000007788 liquid Substances 0.000 description 3
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
229940079593 drug Drugs 0.000 description 2
239000003814 drug Substances 0.000 description 2
235000003599 food sweetener Nutrition 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
238000003801 milling Methods 0.000 description 2
238000002156 mixing Methods 0.000 description 2
230000007935 neutral effect Effects 0.000 description 2
239000003921 oil Substances 0.000 description 2
235000019198 oils Nutrition 0.000 description 2
238000002360 preparation method Methods 0.000 description 2
239000003755 preservative agent Substances 0.000 description 2
239000007787 solid Substances 0.000 description 2
239000000126 substance Substances 0.000 description 2
239000003765 sweetening agent Substances 0.000 description 2
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 2
JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical class OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 1
QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
235000013162 Cocos nucifera Nutrition 0.000 description 1
244000060011 Cocos nucifera Species 0.000 description 1
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 1
CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 description 1
239000004264 Petrolatum Substances 0.000 description 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
239000005557 antagonist Substances 0.000 description 1
239000013011 aqueous formulation Substances 0.000 description 1
125000003289 ascorbyl group Chemical class [H]O[C@@]([H])(C([H])([H])O*)[C@@]1([H])OC(=O)C(O*)=C1O* 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
235000019864 coconut oil Nutrition 0.000 description 1
239000003240 coconut oil Substances 0.000 description 1
238000004040 coloring Methods 0.000 description 1
238000007796 conventional method Methods 0.000 description 1
238000009792 diffusion process Methods 0.000 description 1
239000006185 dispersion Substances 0.000 description 1
238000004090 dissolution Methods 0.000 description 1
229940088679 drug related substance Drugs 0.000 description 1
238000005538 encapsulation Methods 0.000 description 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
239000000796 flavoring agent Substances 0.000 description 1
235000013355 food flavoring agent Nutrition 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
229960001340 histamine Drugs 0.000 description 1
238000010348 incorporation Methods 0.000 description 1
VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
239000000463 material Substances 0.000 description 1
238000002844 melting Methods 0.000 description 1
230000008018 melting Effects 0.000 description 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
238000013508 migration Methods 0.000 description 1
230000005012 migration Effects 0.000 description 1
150000007522 mineralic acids Chemical class 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
235000005985 organic acids Nutrition 0.000 description 1
239000006072 paste Substances 0.000 description 1
229940066842 petrolatum Drugs 0.000 description 1
235000019271 petrolatum Nutrition 0.000 description 1
239000004014 plasticizer Substances 0.000 description 1
239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
229940068968 polysorbate 80 Drugs 0.000 description 1
229920000053 polysorbate 80 Polymers 0.000 description 1
-1 polysorbate 80) or Chemical class 0.000 description 1
239000000843 powder Substances 0.000 description 1
239000000600 sorbitol Substances 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 description 1
125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
229910021653 sulphate ion Inorganic materials 0.000 description 1
239000000725 suspension Substances 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

CY173494A 1989-02-23 1994-05-06 Pharmaceutical capsules containing ranitidine CY1734A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB898904182A GB8904182D0 (en)	1989-02-23	1989-02-23	Pharmaceutical compositions

Publications (1)

Publication Number	Publication Date
CY1734A true CY1734A (en)	1994-05-06

Family

ID=10652220

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CY173494A CY1734A (en)	1989-02-23	1994-05-06	Pharmaceutical capsules containing ranitidine

Country Status (26)

Country	Link
US (1)	US5028432A (fr)
JP (1)	JP2856817B2 (fr)
KR (1)	KR940006271B1 (fr)
AT (1)	AT401727B (fr)
AU (1)	AU629303B2 (fr)
BE (1)	BE1003123A3 (fr)
CA (1)	CA2010692C (fr)
CH (1)	CH680567A5 (fr)
CY (1)	CY1734A (fr)
DE (1)	DE4005650C2 (fr)
DK (1)	DK170209B1 (fr)
FR (1)	FR2643263B1 (fr)
GB (2)	GB8904182D0 (fr)
HK (1)	HK89493A (fr)
HU (1)	HU211930A9 (fr)
IE (1)	IE63179B1 (fr)
IL (1)	IL93490A (fr)
IT (1)	IT1240768B (fr)
LU (1)	LU87681A1 (fr)
NL (1)	NL193267C (fr)
NZ (1)	NZ232642A (fr)
PH (1)	PH26972A (fr)
SA (1)	SA90100287B1 (fr)
SE (1)	SE512412C2 (fr)
ZA (1)	ZA901348B (fr)
ZW (1)	ZW1790A1 (fr)

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* Cited by examiner, † Cited by third party
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WO1992004893A1 (fr) *	1990-09-13	1992-04-02	Smithkline Beecham Corporation	Suspensions orales liquides non aqueuses
US5571533A (en) *	1992-02-07	1996-11-05	Recordati, S.A., Chemical And Pharmaceutical Company	Controlled-release mucoadhesive pharmaceutical composition for the oral administration of furosemide
AU669952B2 (en) *	1992-10-16	1996-06-27	Glaxo Group Limited	Taste-masking compositions of ranitidine
US5433951A (en) *	1993-10-13	1995-07-18	Bristol-Myers Squibb Company	Sustained release formulation containing captopril and method
DE4341310A1 (de) *	1993-12-03	1995-06-08	Hexal Pharma Gmbh	Tablette oder Kapsel mit einem Gehalt an stabilem Ranitidinhydrochlorid Form 1
GB9325445D0 (en)	1993-12-13	1994-02-16	Cortecs Ltd	Pharmaceutical formulations
US5407687A (en) *	1994-02-22	1995-04-18	Glaxo Inc.	Ranitidine solid dosage form
GB9405304D0 (en) *	1994-03-16	1994-04-27	Scherer Ltd R P	Delivery systems for hydrophobic drugs
US5538737A (en) *	1994-11-30	1996-07-23	Applied Analytical Industries, Inc.	Oral compositions of H2 -antagonists
GB9705813D0 (en) *	1997-03-20	1997-05-07	Smithkline Beecham Plc	Novel compositions
AR013261A1 (es) *	1997-08-01	2000-12-13	Smithkline Beecham Corp	Formulaciones farmaceuticas para analogos de camptotecina en capsula de gelatina
ATE374602T1 (de) *	2001-12-21	2007-10-15	Supernus Pharmaceuticals Inc	Orale kapselformulierung mit verbesserter physikalischer stabilität
JP2006518380A (ja) *	2003-01-31	2006-08-10	スミスクライン・ビーチャム・コーポレイション	固体分散体組成物
KR101152470B1 (ko)	2003-08-13	2012-06-01	바이오콘 리미티드	치료제용 마이크로-입자 지방산 염 고형 투약 제형
MX2012013955A (es)	2010-06-23	2013-01-24	Colgate Palmolive Co	Composiciones terapeuticas bucales.
US9161891B2 (en)	2010-12-20	2015-10-20	Colgate-Palmolive Company	Gelatin encapsulated oral care composition containing dental occlusion actives, hydrophobic viscosity modifier and oil carrier
CN107088168A (zh)	2010-12-20	2017-08-25	高露洁-棕榄公司	包含牙齿封闭活性物的非水性口腔护理组合物
CN103260466B (zh)	2010-12-20	2016-08-17	高露洁-棕榄公司	含有亲水性活性物质、疏水性结构化剂和油载体的明胶包囊的口腔护理组合物
US20200038376A1 (en) *	2016-11-01	2020-02-06	Johnson & Johnson Consumer Inc.	Liquid oral pharmaceutical dosage form comprising an histamine h2-receptor antagonist and an antacid
CN109010303B (zh) *	2017-06-09	2021-05-07	苏州科伦药物研究有限公司	一种盐酸雷尼替丁胶囊的工业制备方法
KR102108153B1 (ko) *	2017-07-05	2020-05-07	(주)동구바이오제약	생체 이용률 및 안정성이 개선된 레티노이드를 함유하는 약제학적 조성물
KR102928295B1 (ko) *	2018-09-07	2026-02-13	알.피.쉐러 테크놀러지즈 엘엘씨	경화 및 낮은 hlb 계면 활성제(들)의 첨가를 통한 고체 또는 반고체 지질 기반 제형 안정화

Family Cites Families (22)

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Publication number	Priority date	Publication date	Assignee	Title
US3374146A (en) *	1966-04-18	1968-03-19	American Cyanamid Co	Sustained release encapsulation
DE2360796B2 (de) *	1973-12-06	1977-06-02	Edelfettwerke Werner Schlüter, 2000 Hamburg; Glyco Iberica S.A., Gava, Barcelona (Spanien) Vti: Hegel, K.Th., Dr.; Dickel, K., Dipl.-Ing.; Pat.-Anwälte, 2000 Hamburg und 8000 München	Arzneimittel mit verzoegerter abgabe des wirkstoffs im darm
GB1565966A (en) *	1976-08-04	1980-04-23	Allen & Hanburys Ltd	Aminoalkyl furan derivatives
IT1090703B (it) *	1976-12-03	1985-06-26	Scherer Ltd R P	Perfezionamento nelle composizioni utili quali veicolo per farmaci
JPS5919524B2 (ja) *	1976-12-17	1984-05-07	中外製薬株式会社	安定な１α−ヒドロキシビタミンＤ類含有製剤
GB1572226A (en) *	1977-11-03	1980-07-30	Hoechst Uk Ltd	Pharmaceutical preparations in solid unit dosage form
JPS55136219A (en) *	1979-04-11	1980-10-23	Sumitomo Chem Co Ltd	Diazepam oily drug
EP0040489A1 (fr) *	1980-05-17	1981-11-25	FISONS plc	Mélanges, sels, emballages et compositions pharmaceutiques contenant l'acide 5-(2-hydroxypropoxy)-4-oxo-8-propyl-4H-1-benzopyrane-2-carboxylique ou un de ses dérivés et une antihistamine antagoniste des récepteurs H2
GB2084580B (en) *	1980-10-01	1984-07-04	Glaxo Group Ltd	Aminoalkyl furan derivative
IL63968A (en) *	1980-10-01	1985-10-31	Glaxo Group Ltd	Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
DE3264782D1 (en) *	1981-10-16	1985-08-22	Sanol Arznei Schwarz Gmbh	Medicinal formulation
JPS58174308A (ja) *	1982-04-06	1983-10-13	Fujimoto Seiyaku Kk	レクタルカプセル坐剤
CA1211374A (fr) *	1982-05-14	1986-09-16	Eszter Cholnoky	Compose pharmaceutique contenant plus d'ingredients actifs
DE3237814A1 (de) *	1982-10-12	1984-04-12	Warner-Lambert Co., 07950 Morris Plains, N.J.	Wasserfreie emulsionen und verwendung derselben
EP0152432B1 (fr) *	1983-08-01	1989-03-01	R.P. Scherer Corporation	Procede de liberation entretenue et produit relatif
GB8903804D0 (en) *	1989-02-20	1989-04-05	Sandoz Ltd	Improvements in or relating to organic compounds
GB8426738D0 (en) *	1984-10-23	1984-11-28	Scras	Pyridine derivatives
GB8516083D0 (en) *	1985-06-25	1985-07-31	Glaxo Group Ltd	Heterocyclic compounds
JPH07549B2 (ja) *	1986-07-03	1995-01-11	ゼリア新薬工業株式会社	軟カプセル充填用組成物
DE3629386A1 (de) *	1986-08-29	1988-03-03	Scherer Gmbh R P	Gelatinekapseln und verfahren zu ihrer herstellung
IL90245A (en) *	1988-05-11	1994-04-12	Glaxo Group Ltd	Resin adsorbate comprising ranitidine together with a synthetic cation exchange resin, its preparation and pharmaceutical compositions containing it
JPH0482832A (ja) *	1988-09-20	1992-03-16	Glaxo Group Ltd	医薬組成物

1989
- 1989-02-23 GB GB898904182A patent/GB8904182D0/en active Pending
1990
- 1990-02-21 ZW ZW17/90A patent/ZW1790A1/xx unknown
- 1990-02-21 LU LU87681A patent/LU87681A1/fr unknown
- 1990-02-22 AT AT0042190A patent/AT401727B/de not_active IP Right Cessation
- 1990-02-22 DE DE4005650A patent/DE4005650C2/de not_active Expired - Lifetime
- 1990-02-22 IE IE65190A patent/IE63179B1/en not_active IP Right Cessation
- 1990-02-22 FR FR909002187A patent/FR2643263B1/fr not_active Expired - Lifetime
- 1990-02-22 PH PH40086A patent/PH26972A/en unknown
- 1990-02-22 US US07/482,903 patent/US5028432A/en not_active Expired - Lifetime
- 1990-02-22 AU AU50073/90A patent/AU629303B2/en not_active Expired
- 1990-02-22 NL NL9000428A patent/NL193267C/nl not_active IP Right Cessation
- 1990-02-22 GB GB9004016A patent/GB2229094B/en not_active Expired - Lifetime
- 1990-02-22 IL IL9349090A patent/IL93490A/en not_active IP Right Cessation
- 1990-02-22 KR KR1019900002250A patent/KR940006271B1/ko not_active Expired - Lifetime
- 1990-02-22 ZA ZA901348A patent/ZA901348B/xx unknown
- 1990-02-22 JP JP2042288A patent/JP2856817B2/ja not_active Expired - Lifetime
- 1990-02-22 IT IT47659A patent/IT1240768B/it active IP Right Grant
- 1990-02-22 CH CH569/90A patent/CH680567A5/fr not_active IP Right Cessation
- 1990-02-22 NZ NZ232642A patent/NZ232642A/en unknown
- 1990-02-22 SE SE9000625A patent/SE512412C2/sv unknown
- 1990-02-22 BE BE9000197A patent/BE1003123A3/fr not_active IP Right Cessation
- 1990-02-22 DK DK048090A patent/DK170209B1/da not_active IP Right Cessation
- 1990-02-22 CA CA002010692A patent/CA2010692C/fr not_active Expired - Lifetime
- 1990-06-23 SA SA90100287A patent/SA90100287B1/ar unknown
1993
- 1993-08-26 HK HK894/93A patent/HK89493A/xx not_active IP Right Cessation
1994
- 1994-05-06 CY CY173494A patent/CY1734A/en unknown
1995
- 1995-06-29 HU HU95P/P00543P patent/HU211930A9/hu unknown

Also Published As

Publication number	Publication date
US5028432A (en)	1991-07-02
BE1003123A3 (fr)	1991-12-03
SA90100287B1 (ar)	1999-08-15
IL93490A (en)	1994-07-31
CA2010692A1 (fr)	1990-08-23
JP2856817B2 (ja)	1999-02-10
IT9047659A0 (it)	1990-02-22
IE63179B1 (en)	1995-03-22
HU211930A9 (en)	1996-01-29
FR2643263B1 (fr)	1994-09-16
NL9000428A (nl)	1990-09-17
ZW1790A1 (en)	1991-10-16
GB9004016D0 (en)	1990-04-18
IE900651L (en)	1990-08-23
HK89493A (en)	1993-09-03
KR940006271B1 (ko)	1994-07-14
PH26972A (en)	1992-12-28
DK48090A (da)	1990-08-24
DE4005650A1 (de)	1990-09-06
NZ232642A (en)	1992-07-28
SE9000625D0 (sv)	1990-02-22
LU87681A1 (fr)	1991-10-08
CA2010692C (fr)	1995-12-12
GB2229094A (en)	1990-09-19
DE4005650C2 (de)	1999-03-25
SE512412C2 (sv)	2000-03-13
GB8904182D0 (en)	1989-04-05
IT1240768B (it)	1993-12-17
ATA42190A (de)	1996-04-15
GB2229094B (en)	1993-01-06
IL93490A0 (en)	1990-11-29
NL193267C (nl)	1999-05-06
IT9047659A1 (it)	1991-08-22
JPH03200728A (ja)	1991-09-02
SE9000625L (sv)	1990-08-24
DK170209B1 (da)	1995-06-19
AU629303B2 (en)	1992-10-01
ZA901348B (en)	1991-03-27
DK48090D0 (da)	1990-02-22
NL193267B (nl)	1999-01-04
KR900012612A (ko)	1990-09-01
AU5007390A (en)	1990-08-30
CH680567A5 (fr)	1992-09-30
FR2643263A1 (fr)	1990-08-24
AT401727B (de)	1996-11-25

Publication	Publication Date	Title
US5028432A (en)	1991-07-02	Pharmaceutical capsules containing panetidine
KR910000655B1 (ko)	1991-01-31	신규 형태의 연질캡슐 제조방법
KR930008955B1 (ko)	1993-09-17	비타민류, 식이요법용 보충물등을 함유하는 연질젤용 에탄올 충전제제
WO1986004503A1 (fr)	1986-08-14	Composition pharmaceutique contenant de l'ubidecarenone
EP0734253A1 (fr)	1996-10-02	Formulations de gelule a liberation biphasee
EP0173293B1 (fr)	1991-10-30	Formulations antihistaminiques préparées par fusion chaude
JPH0816051B2 (ja)	1996-02-21	徐放性坐剤
JPS6024767B2 (ja)	1985-06-14	腸溶性硬カプセル剤
EP1033986A1 (fr)	2000-09-13	Formulations contenant de la paroxetine dissoute
US20020032220A1 (en)	2002-03-14	Formulations comprising dissolved paroxetine
WO1997021440A1 (fr)	1997-06-19	Solution contenant de l'ici 182,780 destinee a l'administration par voie orale
EP0431659B1 (fr)	1994-04-20	Compositions pharmaceutiques à base de tébufélone
CA2179041C (fr)	2007-04-10	Formulations de gelule a liberation biphasee
KR20020039354A (ko)	2002-05-25	바소프레신 길항제 제형 및 방법
JPS61200909A (ja)	1986-09-05	経口投与持続性カプセル剤
CA2310407A1 (fr)	1999-06-03	Formulations contenant de la paroxetine dissoute
JPS59106418A (ja)	1984-06-20	ニフエジピン製剤
CZ20001876A3 (cs)	2001-01-17	Prostředky obsahující rozpuštěný paroxetin
MXPA06005247A (es)	2006-10-17	Composicion farmaceutica destinada a la administracion oral de un derivado de pirazol-3-carboxamida
MXPA00005030A (en)	2001-05-07	Formulations comprising dissolved paroxetine