CY1833A - Therapeutic nucleosides - Google Patents

Therapeutic nucleosides

Info

Publication number: CY1833A
Authority: CY; Cyprus
Prior art keywords: therapeutic nucleosides; nucleosides; therapeutic
Prior art date: 1987-08-15

Application number

CY183395A

Other languages

English (en)

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-08-15

Filing date

1995-12-01

Publication date

1995-12-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26292613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1833(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1987-08-15 Priority claimed from GB878719367A external-priority patent/GB8719367D0/en

1987-11-05 Priority claimed from GB878725939A external-priority patent/GB8725939D0/en

1995-12-01 Application filed by Wellcome Found filed Critical Wellcome Found

1995-12-01 Publication of CY1833A publication Critical patent/CY1833A/xx

Links

239000002777 nucleoside Substances 0.000 title 1
125000003835 nucleoside group Chemical group 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)

CY183395A 1987-08-15 1995-12-01 Therapeutic nucleosides CY1833A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB878719367A GB8719367D0 (en)	1987-08-15	1987-08-15	Therapeutic compounds
GB878725939A GB8725939D0 (en)	1987-11-05	1987-11-05	Therapeutic compounds

Publications (1)

Publication Number	Publication Date
CY1833A true CY1833A (en)	1995-12-01

Family

ID=26292613

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CY183395A CY1833A (en)	1987-08-15	1995-12-01	Therapeutic nucleosides

Country Status (30)

Country	Link
EP (2)	EP0596542B1 (cs)
JP (2)	JPH0662623B2 (cs)
KR (2)	KR960002849B1 (cs)
CN (1)	CN1033701C (cs)
AP (2)	AP160A (cs)
AT (1)	ATE138660T1 (cs)
AU (1)	AU612393C (cs)
CS (1)	CS276903B6 (cs)
CY (1)	CY1833A (cs)
DE (1)	DE3855333T2 (cs)
DK (2)	DK170045B1 (cs)
ES (1)	ES2087639T3 (cs)
FI (1)	FI89713C (cs)
GR (1)	GR3020372T3 (cs)
HU (1)	HU201071B (cs)
IE (1)	IE65551B1 (cs)
IL (1)	IL87434A (cs)
LU (1)	LU88746I2 (cs)
LV (1)	LV5264A3 (cs)
MC (1)	MC1968A1 (cs)
MX (1)	MX9203418A (cs)
MY (1)	MY103760A (cs)
NL (1)	NL960001I2 (cs)
NO (2)	NO167805C (cs)
NZ (1)	NZ225809A (cs)
PL (1)	PL158285B1 (cs)
PT (1)	PT88261B (cs)
SA (1)	SA95160244B1 (cs)
SG (1)	SG26346G (cs)
SU (1)	SU1634138A3 (cs)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AP160A (en) *	1987-08-15	1991-11-18	The Wellcome Foundation Ltd	Therapeutic acyclic nucleosides.
GB8816760D0 (en) *	1988-07-14	1988-08-17	Wellcome Found	Therapeutic compounds
GB8829571D0 (en) *	1988-12-19	1989-02-08	Wellcome Found	Antiviral compounds
DE68922903T2 (de) *	1988-12-19	1995-11-23	Wellcome Found	Antivirale Pyrimidin- und Purinverbindungen, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate.
DE4008858A1 (de) *	1990-03-20	1991-09-26	Hoechst Ag	Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel
HU217779B (hu) *	1993-06-08	2000-04-28	Cancer Research Campaign Technology Limited	O6-Helyettesített guaninszármazékok, ezeket tartalmazó gyógyászati készítmények, valamint eljárás e vegyületek előállítására
DE69426880T2 (de) *	1993-06-10	2001-10-31	Rolabo S.L., Zaragoza	Verfahren zur herstellung von aminosäureester von nukleosid analogen
GB9317146D0 (en) *	1993-08-18	1993-10-06	Wellcome Found	Therapeutic combinations
GB9320316D0 (en) *	1993-10-01	1993-11-17	Smithkline Beecham Plc	Pharmaceuticals
TW282470B (cs) *	1993-11-18	1996-08-01	Ajinomoto Kk
DE69513313T2 (de) *	1994-02-01	2000-07-13	Ajinomoto Co., Inc.	Verfahren zur Herstellung von Nukleinsäurebasenderivaten
US5840891A (en) *	1994-07-28	1998-11-24	Syntex (U.S.A.) Inc.	2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5543414A (en) *	1994-07-28	1996-08-06	Syntex (Usa) Inc.	Achiral amino acid acyl esters of ganciclovir and its derivatives
PE32296A1 (es) *	1994-07-28	1996-08-07	Hoffmann La Roche	Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables
GB9501127D0 (en) *	1995-01-20	1995-03-08	Wellcome Found	Tablet
GB9501142D0 (en) *	1995-01-20	1995-03-08	Wellcome Found	Compounds for use in medicine
GB9501178D0 (en) *	1995-01-20	1995-03-08	Wellcome Found	Guanine derivative
DE19536164A1 (de) *	1995-09-28	1997-04-03	Boehringer Ingelheim Kg	Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
CA2243237C (en) *	1996-01-19	2008-09-02	Glaxo Group Limited	Use of valaciclovir for the manufacture of a medicament for the treatment of genital herpes by a single daily application
US5700936A (en) *	1996-01-26	1997-12-23	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5840890A (en) *	1996-01-26	1998-11-24	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6040446A (en)	1996-01-26	2000-03-21	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
DE69714971T3 (de) *	1996-01-26	2005-12-15	F. Hoffmann-La Roche Ag	Verfahren zur herstellung von purin-derivaten
US5756736A (en) *	1996-01-26	1998-05-26	Syntex (U.S.A.) Inc.	Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US6703394B2 (en)	1996-02-16	2004-03-09	Medivir Ab	Acyclic nucleoside derivatives
US5869493A (en) *	1996-02-16	1999-02-09	Medivir Ab	Acyclic nucleoside derivatives
IT1283447B1 (it) *	1996-07-18	1998-04-21	Ind Chimica Srl	Processo di preparazione del valaciclovir e relativi intermedi
WO1998031683A1 (en) *	1997-01-17	1998-07-23	Ajinomoto Co., Inc.	Novel z-valacyclovir crystals
CA2332961A1 (en) *	1998-05-21	1999-11-25	Michael Zasloff	A method for stimulation of defensin production by exposure to isoleucine
HUP0500753A3 (en) *	2001-09-07	2006-05-29	Teva Pharma	Crystalline forms of valacyclovir hydrochloride
WO2004000265A2 (en)	2002-06-24	2003-12-31	Ranbaxy Laboratories Limited	Process for the preparation of robust formulations of valacyclovir hydrochloride tablets
US20050043329A1 (en) *	2002-09-06	2005-02-24	Shlomit Wizel	Crystalline forms of valacyclovir hydrochloride
CN1309732C (zh) *	2002-10-28	2007-04-11	南京长澳医药科技有限公司	6－烷氧基－2’，3’－双脱氧鸟嘌呤核苷的制备方法
KR100871621B1 (ko) *	2003-06-02	2008-12-02	테바 파마슈티컬 인더스트리즈 리미티드	발라시클로비르 히드로클로라이드의 신규한 결정질 형태
CN1331471C (zh) *	2003-09-22	2007-08-15	陈云芳	盐酸万乃洛韦软胶囊组合物
JP2007522130A (ja) *	2004-01-21	2007-08-09	テバファーマシューティカルインダストリーズリミティド	塩酸バラシクロビルの調製方法
GB2413017A (en) *	2004-04-06	2005-10-12	Ford Global Tech Llc	An electrical connector for a vehicle
WO2006035452A1 (en) *	2004-09-27	2006-04-06	Matrix Laboratories Ltd	Novel pseudomorph of valaciclovir hydrochloride
ATE546451T1 (de)	2005-05-25	2012-03-15	Lilly Co Eli	Cyclopropancarbonsäureester von acyclovir
EP1746098A1 (en)	2005-07-21	2007-01-24	SOLMAG S.p.A.	Valacyclovir polymorphs and a process for the preparation thereof
CN101456859B (zh) *	2009-01-06	2011-07-20	华南理工大学	抗病毒药物缬昔洛韦的制备方法
WO2011158252A1 (en)	2010-06-15	2011-12-22	Matrix Laboratories Ltd	Process for the preparation of valacyclovir hydrochloride polymorphic form ii
CN102850354B (zh) *	2012-10-10	2014-07-23	山东金城医药化工股份有限公司	高纯度cbz-万乃洛韦的制备方法
CN106632335A (zh) *	2016-12-27	2017-05-10	河南康达制药有限公司	一种盐酸伐昔洛韦的制备方法
RU2750867C1 (ru) *	2020-05-18	2021-07-05	Александр Сергеевич Самойлов	Производные гуанина

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8202626A (nl) *	1982-06-29	1984-01-16	Stichting Rega V Z W	Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
DE3627024A1 (de) *	1985-09-24	1987-04-02	Hoechst Ag	In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
DE3534774A1 (de) *	1985-09-30	1987-04-02	Robugen Gmbh	Nucleosid-analoge verbindungen mit antiviraler aktivitaet, verfahren zu deren herstellung sowie arzneimittel mit antiviraler wirkung
AP160A (en) *	1987-08-15	1991-11-18	The Wellcome Foundation Ltd	Therapeutic acyclic nucleosides.

1988
- 1988-08-10 AP APAP/P/1991/000238A patent/AP160A/en active
- 1988-08-10 AP APAP/P/1988/000099A patent/AP55A/en active
- 1988-08-11 MC MC881999A patent/MC1968A1/fr unknown
- 1988-08-12 IE IE246388A patent/IE65551B1/en not_active IP Right Cessation
- 1988-08-12 KR KR1019880010298A patent/KR960002849B1/ko not_active Expired - Lifetime
- 1988-08-12 MY MYPI88000934A patent/MY103760A/en unknown
- 1988-08-12 DE DE3855333T patent/DE3855333T2/de not_active Expired - Lifetime
- 1988-08-12 IL IL87434A patent/IL87434A/xx not_active IP Right Cessation
- 1988-08-12 LU LU88746C patent/LU88746I2/fr unknown
- 1988-08-12 HU HU884332A patent/HU201071B/hu unknown
- 1988-08-12 AU AU20978/88A patent/AU612393C/en not_active Expired
- 1988-08-12 EP EP93120604A patent/EP0596542B1/en not_active Expired - Lifetime
- 1988-08-12 SU SU884356404A patent/SU1634138A3/ru active
- 1988-08-12 PL PL1988274215A patent/PL158285B1/pl unknown
- 1988-08-12 NZ NZ225809A patent/NZ225809A/en unknown
- 1988-08-12 FI FI883757A patent/FI89713C/fi not_active IP Right Cessation
- 1988-08-12 CS CS885594A patent/CS276903B6/cs not_active IP Right Cessation
- 1988-08-12 CN CN88106535A patent/CN1033701C/zh not_active Expired - Lifetime
- 1988-08-12 JP JP63200320A patent/JPH0662623B2/ja not_active Expired - Lifetime
- 1988-08-12 DK DK451388A patent/DK170045B1/da not_active IP Right Cessation
- 1988-08-12 AT AT93120604T patent/ATE138660T1/de not_active IP Right Cessation
- 1988-08-12 ES ES93120604T patent/ES2087639T3/es not_active Expired - Lifetime
- 1988-08-12 EP EP88307512A patent/EP0308065B1/en not_active Expired - Lifetime
- 1988-08-12 PT PT88261A patent/PT88261B/pt not_active IP Right Cessation
- 1988-08-12 NO NO883612A patent/NO167805C/no not_active IP Right Cessation
1990
- 1990-08-28 JP JP2226434A patent/JPH07113025B2/ja not_active Expired - Lifetime
1992
- 1992-06-25 MX MX9203418A patent/MX9203418A/es unknown
- 1992-12-18 LV LV920335A patent/LV5264A3/xx unknown
1994
- 1994-07-08 DK DK082694A patent/DK170803B1/da not_active IP Right Cessation
1995
- 1995-02-24 SG SG1995903373A patent/SG26346G/en unknown
- 1995-09-20 SA SA95160244A patent/SA95160244B1/ar unknown
- 1995-12-01 CY CY183395A patent/CY1833A/xx unknown
1996
- 1996-01-17 KR KR1019960000775A patent/KR960004940B1/ko not_active Expired - Lifetime
- 1996-01-18 NL NL960001C patent/NL960001I2/nl unknown
- 1996-06-27 GR GR960401743T patent/GR3020372T3/el unknown
- 1996-12-17 NO NO1996015C patent/NO1996015I1/no unknown

Also Published As

Publication number	Publication date
PL274215A1 (en)	1990-02-19
SU1634138A3 (ru)	1991-03-07
AP160A (en)	1991-11-18
CN1033701C (zh)	1997-01-01
CS8805594A2 (en)	1990-06-13
NZ225809A (en)	1991-07-26
IE882463L (en)	1989-02-15
IL87434A (en)	1993-06-10
GR3020372T3 (en)	1996-09-30
CN1032538A (zh)	1989-04-26
PL158285B1 (en)	1992-08-31
AP8800099A0 (en)	1988-08-01
EP0596542B1 (en)	1996-05-29
MY103760A (en)	1993-09-30
DK170045B1 (da)	1995-05-08
EP0308065A3 (en)	1989-09-27
MX9203418A (es)	1992-07-01
FI89713C (fi)	1993-11-10
DK451388A (da)	1989-02-16
AU612393B2 (en)	1991-07-11
PT88261A (pt)	1989-06-30
DE3855333D1 (de)	1996-07-04
IE65551B1 (en)	1995-11-01
DK170803B1 (da)	1996-01-22
IL87434A0 (en)	1989-01-31
JPH07113025B2 (ja)	1995-12-06
CS276903B6 (en)	1992-09-16
SA95160244B1 (ar)	2006-10-02
ATE138660T1 (de)	1996-06-15
FI883757L (fi)	1989-02-16
MC1968A1 (fr)	1989-09-29
DK451388D0 (da)	1988-08-12
NL960001I2 (nl)	1996-11-01
ES2087639T3 (es)	1996-07-16
PT88261B (pt)	1995-03-01
AU2097888A (en)	1989-02-16
EP0596542A1 (en)	1994-05-11
EP0308065B1 (en)	1995-01-04
HU201071B (en)	1990-09-28
JPS6468373A (en)	1989-03-14
HUT47935A (en)	1989-04-28
DE3855333T2 (de)	1996-12-05
KR960002849B1 (ko)	1996-02-27
FI89713B (fi)	1993-07-30
FI883757A0 (fi)	1988-08-12
LU88746I2 (fr)	1996-10-04
NO167805C (no)	1991-12-11
SG26346G (en)	1995-09-01
JPH03115284A (ja)	1991-05-16
JPH0662623B2 (ja)	1994-08-17
NO883612L (no)	1989-02-16
LV5264A3 (lv)	1993-10-10
AU612393C (en)	2006-08-17
KR890003761A (ko)	1989-04-17
EP0308065A2 (en)	1989-03-22
KR960004940B1 (ko)	1996-04-18
NO1996015I1 (no)	1996-12-17
NL960001I1 (nl)	1996-03-01
DK82694A (da)	1994-07-08
AP55A (en)	1989-09-26
NO167805B (no)	1991-09-02
NO883612D0 (no)	1988-08-12

Publication	Publication Date	Title
PH29942A (en)	1996-09-16	Therapeutic nucleosides
CY1833A (en)	1995-12-01	Therapeutic nucleosides
GB8815265D0 (en)	1988-08-03	Therapeutic nucleosides
EP0434450A3 (en)	1992-07-08	Therapeutic nucleosides
AP8800086A0 (en)	1988-02-01	Therapeutic nucleosides
EP0356166A3 (en)	1990-09-12	Therapeutic nucleosides
PH24812A (en)	1990-10-30	Therapeutic nucleosides
ZA881842B (en)	1989-11-29	Therapeutic nucleosides
GB8712691D0 (en)	1987-07-01	Therapeutic nucleosides
GB8823353D0 (en)	1988-11-09	Therapeutic nucleosides
GB8912972D0 (en)	1989-07-26	Therapeutic nucleosides
GB8723013D0 (en)	1987-11-04	Therapeutic nucleosides
GB8723746D0 (en)	1987-11-11	Therapeutic nucleosides
GB8723747D0 (en)	1987-11-11	Therapeutic nucleosides
GB8723793D0 (en)	1987-11-11	Therapeutic nucleosides
ZA882477B (en)	1989-12-27	Therapeutic nucleosides
PH29941A (en)	1996-09-16	Therapeutic nucleosides
IE861273L (en)	1986-11-15	Therapeutic nucleosides
IE862454L (en)	1987-03-17	therapeutic nucleosides
ZA896328B (en)	1991-04-24	Therapeutic nucleosides
IE883328L (en)	1989-05-07	Therapeutic nucleosides
IE881047L (en)	1988-10-09	Therapeutic nucleosides
GB8816284D0 (en)	1988-08-10	Therapeutic nucleosides
IE880748L (en)	1988-09-16	Therapeutic nucleosides
GB8824899D0 (en)	1988-11-30	Therapeutic nucleosides