DD201889A5 - Verfahren zur herstellung von neuen indolinonen - Google Patents

Verfahren zur herstellung von neuen indolinonen Download PDF

Info

Publication number
DD201889A5
DD201889A5 DD81234742A DD23474281A DD201889A5 DD 201889 A5 DD201889 A5 DD 201889A5 DD 81234742 A DD81234742 A DD 81234742A DD 23474281 A DD23474281 A DD 23474281A DD 201889 A5 DD201889 A5 DD 201889A5
Authority
DD
German Democratic Republic
Prior art keywords
indolinone
dimethyl
general formula
group
theory
Prior art date
Application number
DD81234742A
Other languages
German (de)
English (en)
Inventor
Erich Mueller
Josef Nickl
Josef Roch
Berthold Narr
Walter Haarmann
Johannes M Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of DD201889A5 publication Critical patent/DD201889A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD81234742A 1980-11-12 1981-11-10 Verfahren zur herstellung von neuen indolinonen DD201889A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3042632 1980-11-12

Publications (1)

Publication Number Publication Date
DD201889A5 true DD201889A5 (de) 1983-08-17

Family

ID=6116579

Family Applications (1)

Application Number Title Priority Date Filing Date
DD81234742A DD201889A5 (de) 1980-11-12 1981-11-10 Verfahren zur herstellung von neuen indolinonen

Country Status (29)

Country Link
US (1) US4629733A (fr)
JP (1) JPS57114569A (fr)
KR (1) KR880002227B1 (fr)
AT (1) AT375923B (fr)
AU (1) AU547929B2 (fr)
BE (1) BE891103A (fr)
CA (1) CA1183848A (fr)
CH (1) CH652120A5 (fr)
DD (1) DD201889A5 (fr)
DK (1) DK154138C (fr)
ES (2) ES8206470A1 (fr)
FI (1) FI75806C (fr)
FR (1) FR2493841A1 (fr)
GB (1) GB2098595B (fr)
GR (1) GR81330B (fr)
HU (1) HU183680B (fr)
IE (1) IE52107B1 (fr)
IL (1) IL64252A (fr)
IT (1) IT1171624B (fr)
LU (1) LU83744A1 (fr)
NL (1) NL8105100A (fr)
NO (1) NO156167C (fr)
NZ (1) NZ198941A (fr)
PL (1) PL134525B1 (fr)
PT (1) PT73969B (fr)
SE (1) SE452156B (fr)
SU (1) SU1107759A3 (fr)
YU (1) YU41995B (fr)
ZA (1) ZA817787B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0089394A1 (fr) * 1982-03-23 1983-09-28 Sterling Drug Inc. Dérivés de l'indole 1-H,2,3-dione et leur préparation
US5204344A (en) * 1989-08-22 1993-04-20 Merck Frosst Canada, Inc. (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes
US5272145A (en) * 1989-08-22 1993-12-21 Merck Frosst Canada, Inc. (Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes
GB9008605D0 (en) * 1990-04-17 1990-06-13 Smith Kline French Lab Process
US5190968A (en) * 1991-09-30 1993-03-02 Merck Frosst Canada, Inc. (Polycyclic-arylmethoxy) indoles as inhibitors of leukotriene biosynthesis
US5308850A (en) * 1991-09-30 1994-05-03 Merck Frosst Canada, Inc. (Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5389650A (en) * 1991-09-30 1995-02-14 Merck Frosst Canada, Inc. (Azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5290798A (en) * 1991-09-30 1994-03-01 Merck Frosst Canada, Inc. (hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5374635A (en) * 1993-03-29 1994-12-20 Merck Frosst Canada, Inc. Furo[3,2-b]pyridines and thieno[3,2-b]pyridines as inhibitors of leukotriene biosynthesis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT330169B (de) * 1971-06-24 1976-06-25 Sandoz Ag Verfahren zur herstellung neuer oxindole und ihrer salze
SU843739A3 (ru) * 1978-02-17 1981-06-30 Карл Томэ Гмбх (Фирма) Способ получени карбостириловыхили ОКСиНдОлОВыХ пРОизВОдНыХ
DE2853314A1 (de) * 1978-12-09 1980-06-26 Thomae Gmbh Dr K Neue carbostyril- und oxindolderivate, ihre herstellung und ihre verwendung als arzneimittel
US4329347A (en) * 1978-02-17 1982-05-11 Boehringer Ingelheim Gmbh Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril
US4442111A (en) * 1981-07-25 1984-04-10 Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung Antithrombotic sulfimino and sulfoximino indolinones-2

Also Published As

Publication number Publication date
AT375923B (de) 1984-09-25
SE452156B (sv) 1987-11-16
ES511834A0 (es) 1983-02-16
FI75806C (fi) 1988-08-08
ZA817787B (en) 1983-07-27
PT73969B (de) 1983-11-23
SE8106704L (sv) 1982-05-13
US4629733A (en) 1986-12-16
ES507015A0 (es) 1982-08-16
NO156167B (no) 1987-04-27
IL64252A0 (en) 1982-02-28
PL233774A1 (fr) 1982-12-20
KR880002227B1 (ko) 1988-10-20
YU41995B (en) 1988-04-30
FI75806B (fi) 1988-04-29
GB2098595A (en) 1982-11-24
PL134525B1 (en) 1985-08-31
PT73969A (de) 1981-12-01
SU1107759A3 (ru) 1984-08-07
BE891103A (fr) 1982-05-12
AU7739081A (en) 1982-05-20
NO813821L (no) 1982-05-13
YU266681A (en) 1983-10-31
DK154138B (da) 1988-10-17
IL64252A (en) 1985-02-28
AU547929B2 (en) 1985-11-14
IT1171624B (it) 1987-06-10
DK496781A (da) 1982-05-13
HU183680B (en) 1984-05-28
IE52107B1 (en) 1987-06-24
IT8149602A1 (it) 1983-04-30
KR830007554A (ko) 1983-10-21
ES8304081A1 (es) 1983-02-16
ES8206470A1 (es) 1982-08-16
GB2098595B (en) 1984-09-05
FR2493841B1 (fr) 1984-03-30
FI813561L (fi) 1982-05-13
IE812640L (en) 1982-05-12
NZ198941A (en) 1984-10-19
JPS57114569A (en) 1982-07-16
CH652120A5 (de) 1985-10-31
DK154138C (da) 1989-04-17
ATA478981A (de) 1984-02-15
NL8105100A (nl) 1982-06-01
IT8149602A0 (it) 1981-10-30
GR81330B (fr) 1984-12-11
LU83744A1 (de) 1983-04-13
FR2493841A1 (fr) 1982-05-14
CA1183848A (fr) 1985-03-12
NO156167C (no) 1987-08-05

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