DD252614A5 - Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen - Google Patents

Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen Download PDF

Info

Publication number: DD252614A5
Authority: DD; German Democratic Republic
Prior art keywords: dna; plasmid; dna fragment; fragment; hepatitis
Prior art date: 1985-11-26

Application number

DD29662586A

Other languages

German (de)

English (en)

Inventor

Juerg F Tschopp

Michael M Harpold

James M Cregg

Richard G Buckholz

Original Assignee

Phillips Petroleum Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-11-26

Filing date

1986-11-25

Publication date

1987-12-23

1986-11-25 Application filed by Phillips Petroleum Co filed Critical Phillips Petroleum Co

1987-12-23 Publication of DD252614A5 publication Critical patent/DD252614A5/de

Links

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235000015598 salt intake Nutrition 0.000 description 1
238000003345 scintillation counting Methods 0.000 description 1
238000012216 screening Methods 0.000 description 1
238000011218 seed culture Methods 0.000 description 1
239000013605 shuttle vector Substances 0.000 description 1
239000002002 slurry Substances 0.000 description 1
239000001509 sodium citrate Substances 0.000 description 1
NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
239000012064 sodium phosphate buffer Substances 0.000 description 1
NQWDJIVXKGLAAT-UHFFFAOYSA-M sodium;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetic acid;dodecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O.OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O NQWDJIVXKGLAAT-UHFFFAOYSA-M 0.000 description 1
239000002689 soil Substances 0.000 description 1
230000007928 solubilization Effects 0.000 description 1
238000005063 solubilization Methods 0.000 description 1
230000037351 starvation Effects 0.000 description 1
239000000758 substrate Substances 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
238000010998 test method Methods 0.000 description 1
238000009210 therapy by ultrasound Methods 0.000 description 1
238000000844 transformation Methods 0.000 description 1
238000011426 transformation method Methods 0.000 description 1
229960005486 vaccine Drugs 0.000 description 1
239000011534 wash buffer Substances 0.000 description 1
239000003643 water by type Substances 0.000 description 1
238000001262 western blot Methods 0.000 description 1
239000012138 yeast extract Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Mycology (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Virology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Beans For Foods Or Fodder (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DD29662586A 1985-11-26 1986-11-25 Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen DD252614A5 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/801,713 US4895800A (en)	1985-11-26	1985-11-26	Yeast production of hepatitis B surface antigen

Publications (1)

Publication Number	Publication Date
DD252614A5 true DD252614A5 (de)	1987-12-23

Family

ID=25181867

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DD29662586A DD252614A5 (de)	1985-11-26	1986-11-25	Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen

Country Status (28)

Country	Link
US (1)	US4895800A (fr)
EP (1)	EP0226846B1 (fr)
JP (1)	JPH0763372B2 (fr)
KR (1)	KR920004050B1 (fr)
CN (1)	CN86107885A (fr)
AT (1)	ATE92527T1 (fr)
AU (1)	AU583683B2 (fr)
CA (1)	CA1285895C (fr)
CS (1)	CS276453B6 (fr)
DD (1)	DD252614A5 (fr)
DE (1)	DE3688831T2 (fr)
DK (1)	DK565186A (fr)
EG (1)	EG17949A (fr)
ES (1)	ES2058055T3 (fr)
FI (1)	FI95929C (fr)
HU (1)	HUT43112A (fr)
IE (1)	IE64519B1 (fr)
IL (1)	IL80754A (fr)
IN (1)	IN166428B (fr)
MX (1)	MX4334A (fr)
NO (1)	NO176025C (fr)
NZ (1)	NZ218286A (fr)
PH (2)	PH25941A (fr)
PL (1)	PL152882B1 (fr)
PT (1)	PT83819B (fr)
TW (1)	TW215457B (fr)
YU (1)	YU46031B (fr)
ZA (1)	ZA868601B (fr)

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CA2202351A1 (fr) *	1994-10-18	1996-04-25	George Phillip Vlasuk	Proteines anticoagulantes et inhibiteurs de la serine-protease extraits de nematodes
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1985
- 1985-11-26 US US06/801,713 patent/US4895800A/en not_active Expired - Lifetime
1986
- 1986-07-10 CA CA000513467A patent/CA1285895C/fr not_active Expired - Lifetime
- 1986-11-12 IN IN819/CAL/86A patent/IN166428B/en unknown
- 1986-11-12 ZA ZA868601A patent/ZA868601B/xx unknown
- 1986-11-12 MX MX433486A patent/MX4334A/es unknown
- 1986-11-13 NZ NZ218286A patent/NZ218286A/en unknown
- 1986-11-14 IE IE302186A patent/IE64519B1/en not_active IP Right Cessation
- 1986-11-19 AU AU65384/86A patent/AU583683B2/en not_active Expired
- 1986-11-24 PH PH34520A patent/PH25941A/en unknown
- 1986-11-24 EG EG733/86A patent/EG17949A/xx active
- 1986-11-24 CN CN198686107885A patent/CN86107885A/zh active Pending
- 1986-11-25 HU HU864873A patent/HUT43112A/hu unknown
- 1986-11-25 DK DK565186A patent/DK565186A/da not_active Application Discontinuation
- 1986-11-25 AT AT86116302T patent/ATE92527T1/de active
- 1986-11-25 IL IL80754A patent/IL80754A/xx unknown
- 1986-11-25 DD DD29662586A patent/DD252614A5/de unknown
- 1986-11-25 DE DE86116302T patent/DE3688831T2/de not_active Expired - Lifetime
- 1986-11-25 ES ES86116302T patent/ES2058055T3/es not_active Expired - Lifetime
- 1986-11-25 NO NO864704A patent/NO176025C/no not_active IP Right Cessation
- 1986-11-25 FI FI864791A patent/FI95929C/fi not_active IP Right Cessation
- 1986-11-25 EP EP86116302A patent/EP0226846B1/fr not_active Expired - Lifetime
- 1986-11-25 YU YU201386A patent/YU46031B/sh unknown
- 1986-11-25 KR KR1019860010018A patent/KR920004050B1/ko not_active Expired
- 1986-11-25 JP JP61280567A patent/JPH0763372B2/ja not_active Expired - Fee Related
- 1986-11-26 CS CS868641A patent/CS276453B6/cs unknown
- 1986-11-26 PL PL1986262598A patent/PL152882B1/pl unknown
- 1986-11-26 PT PT83819A patent/PT83819B/pt not_active IP Right Cessation
- 1986-12-01 TW TW075105699A patent/TW215457B/zh active
1987
- 1987-11-06 PH PH36040A patent/PH25539A/en unknown

Also Published As

Publication number	Publication date
ATE92527T1 (de)	1993-08-15
IL80754A0 (en)	1987-02-27
DE3688831T2 (de)	1993-11-25
DK565186A (da)	1987-05-27
FI95929B (fi)	1995-12-29
FI95929C (fi)	1996-04-10
PL152882B1 (en)	1991-02-28
YU201386A (en)	1988-10-31
EP0226846B1 (fr)	1993-08-04
KR920004050B1 (ko)	1992-05-23
US4895800A (en)	1990-01-23
NO864704D0 (no)	1986-11-25
DK565186D0 (da)	1986-11-25
PT83819B (pt)	1988-10-14
AU583683B2 (en)	1989-05-04
FI864791L (fi)	1987-05-27
IN166428B (fr)	1990-05-05
JPS62190085A (ja)	1987-08-20
ZA868601B (en)	1987-06-24
IE64519B1 (en)	1995-08-09
AU6538486A (en)	1987-05-28
PT83819A (en)	1986-12-01
PH25539A (en)	1991-07-24
NO176025B (no)	1994-10-10
KR870005099A (ko)	1987-06-04
EG17949A (en)	1991-03-30
JPH0763372B2 (ja)	1995-07-12
CS276453B6 (en)	1992-06-17
TW215457B (fr)	1993-11-01
CS864186A3 (en)	1992-01-15
HUT43112A (en)	1987-09-28
IE863021L (en)	1987-05-26
IL80754A (en)	1993-03-15
NO176025C (no)	1995-01-18
NZ218286A (en)	1991-07-26
PL262598A1 (en)	1987-09-21
ES2058055T3 (es)	1994-11-01
EP0226846A1 (fr)	1987-07-01
YU46031B (sh)	1992-12-21
PH25941A (en)	1991-12-19
CA1285895C (fr)	1991-07-09
CN86107885A (zh)	1987-09-23
DE3688831D1 (de)	1993-09-09
MX4334A (es)	1993-12-01
FI864791A0 (fi)	1986-11-25

Legal Events

Date	Code	Title	Description
1994-07-21	RPI	Change in the person, name or address of the patentee (searches according to art. 11 and 12 extension act)
1994-07-21	RPV	Change in the person, the name or the address of the representative (searches according to art. 11 and 12 extension act)
2004-04-28	ASS	Change of applicant or owner	Owner name: RESEARCH CORPORATION TECHNOLOGIES, INC Effective date: 19940503
2004-04-28	IF04	In force in the year 2004	Expiry date: 20061126

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DD252614A5 (de)	1987-12-23	Verfahren zur Herstellung von Hepatitis B-Oberflächenantigenen
DE69031556T2 (de)	1998-05-14	Antigene sowie Verfahren zu deren Herstellung
DE69228497T2 (de)	1999-07-15	Expression von menschlichen Serum-Albuminen in Pichia Pastoris
DE3689411T2 (de)	1994-07-21	Methode zur erhöten Expression von Polypeptiden in Hefe des Gattung Pichia.
DE3586889T2 (de)	1993-04-15	Regulatorregion fuer die expression von heterologen genen in hefe.
DE69132812T2 (de)	2002-06-20	Pichia pastoris Säure-Phosphatase-Gen
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DE68912777T2 (de)	1994-05-11	Insulin-analoge.
DE3280468T2 (de)	1995-12-07	Synthese von menschlichen Virusantigenen durch Hefe.
DE68927921T2 (de)	1997-07-17	Expression von Hepatitis B S und preS2 Proteinen in methylotrophen Hefen
DE68928380T2 (de)	1998-02-26	Expression von menschlichen Serumalbumin in methylotrophischen Hefen
DD284899A5 (de)	1990-11-28	Verfahren zur herstellung eines plasmodium-impfstoffes
DE69233031T2 (de)	2003-12-24	Hefepromotor und seine verwendung
DE3689899T2 (de)	1994-09-15	Verfahren und hybridpromotor zur steuerung der exogenen gentranskription.
DE69034051T2 (de)	2003-11-27	Stabil transformierte Hefezellen und ihre Verwendung zur Herstellung von Albumin
DE69133525T2 (de)	2006-11-23	Verfahren zur Herstellung von recombinantem Hepatitis B Oberflächenantigen mit erhöhter Immunogen-Kapazität und Verwendung in einer Impfstoffzubereitung
DE3588117T2 (de)	1997-03-20	Zubereitung für die Herstellung von Hepatitis B Virus-Oberflächenantigen und polymerisierten Humanserumalbuminrezeptor tragende Partikel enthaltenden Vakzinen, tierische Zellen für die Herstellung von diesen Partikeln und Verfahren für ihre Erhaltung
DE69321235T2 (de)	1999-04-01	Promoter vom k. lactis pyruvat-decarboxylase gen und anwendung davon
DD283836A5 (de)	1990-10-24	Verfahren zur bildung von antigenen hbv-teilchen
DE3887425T2 (de)	1994-06-23	BAR1-Sekretions-Signal-Sequenz.
DE69433222T2 (de)	2004-08-19	Mutanter AOX2-Promotor
DE3588244T2 (de)	2003-09-11	Rekombinanter Herpes Simplex gB-gD-Impfstoff
DE69121159T2 (de)	1997-03-13	Wirt-Vektor-System
DD257646A5 (de)	1988-06-22	Verfahren zur Herstellung von Streptokinase