DK0402152T3 - Fremgangsmåde til fremstilling af 4-amino-1-hydroxybutyliden-1,1-bisphosphonsyre eller salte deraf - Google Patents

Fremgangsmåde til fremstilling af 4-amino-1-hydroxybutyliden-1,1-bisphosphonsyre eller salte deraf

Info

Publication number
DK0402152T3
DK0402152T3 DK90306238.8T DK90306238T DK0402152T3 DK 0402152 T3 DK0402152 T3 DK 0402152T3 DK 90306238 T DK90306238 T DK 90306238T DK 0402152 T3 DK0402152 T3 DK 0402152T3
Authority
DK
Denmark
Prior art keywords
salts
amino
hydroxybutylidene
preparation
bisphosphonic acid
Prior art date
Application number
DK90306238.8T
Other languages
English (en)
Inventor
Gerald R Kieczykowski
David G Melillo
Ronald B Jobson
Gerald S Brenner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23431886&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0402152(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK0402152T3 publication Critical patent/DK0402152T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Seasonings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK90306238.8T 1989-06-09 1990-06-08 Fremgangsmåde til fremstilling af 4-amino-1-hydroxybutyliden-1,1-bisphosphonsyre eller salte deraf DK0402152T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/363,820 US4922007A (en) 1989-06-09 1989-06-09 Process for preparing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof

Publications (1)

Publication Number Publication Date
DK0402152T3 true DK0402152T3 (da) 1995-12-04

Family

ID=23431886

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90306238.8T DK0402152T3 (da) 1989-06-09 1990-06-08 Fremgangsmåde til fremstilling af 4-amino-1-hydroxybutyliden-1,1-bisphosphonsyre eller salte deraf

Country Status (23)

Country Link
US (1) US4922007A (da)
EP (1) EP0402152B1 (da)
JP (2) JPH0662651B2 (da)
KR (1) KR0137455B1 (da)
AT (1) ATE129713T1 (da)
AU (1) AU625704C (da)
CA (1) CA2018477C (da)
CH (1) CH0402152H1 (da)
CY (1) CY1894A (da)
DE (1) DE69023280T2 (da)
DK (1) DK0402152T3 (da)
ES (1) ES2080116T3 (da)
FI (1) FI93219C (da)
GR (1) GR3018379T3 (da)
HK (1) HK69596A (da)
HU (1) HU211908A9 (da)
IE (1) IE69564B1 (da)
IL (1) IL94612A (da)
LV (1) LV11472B (da)
NO (2) NO177997C (da)
NZ (1) NZ233972A (da)
PT (1) PT94306B (da)
ZA (1) ZA904446B (da)

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IT1196315B (it) * 1984-10-29 1988-11-16 Gentili Ist Spa Procedimento per la preparazione di acidi difosfonici

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HK69596A (en) 1996-04-26
PT94306A (pt) 1991-02-08
EP0402152A3 (en) 1991-07-03
IL94612A0 (en) 1991-04-15
AU5701990A (en) 1990-12-13
NO177997B (no) 1995-09-25
FI93219B (fi) 1994-11-30
EP0402152A2 (en) 1990-12-12
FI902845A0 (fi) 1990-06-07
AU625704B2 (en) 1992-07-16
CY1894A (en) 1990-06-08
PT94306B (pt) 1997-05-28
NO178228B (no) 1995-11-06
GR3018379T3 (en) 1996-03-31
LV11472A (lv) 1996-08-20
NO178228C (no) 1996-02-14
JPH0662651B2 (ja) 1994-08-17
DE69023280T2 (de) 1996-06-20
KR910000768A (ko) 1991-01-30
IE902073L (en) 1990-12-09
NO902559D0 (no) 1990-06-08
NO902559L (no) 1990-12-10
LV11472B (en) 1996-12-20
IE69564B1 (en) 1996-10-02
KR0137455B1 (ko) 1998-05-01
CA2018477A1 (en) 1990-12-09
NO177997C (no) 1996-01-03
CH0402152H1 (fr) 2006-02-28
IL94612A (en) 1995-03-30
JPH0748391A (ja) 1995-02-21
NO941726L (no) 1990-12-10
JPH03101684A (ja) 1991-04-26
NO941726D0 (no) 1994-05-09
CA2018477C (en) 1995-08-01
HU211908A9 (en) 1996-01-29
AU625704C (en) 2001-07-26
ZA904446B (en) 1992-06-24
NZ233972A (en) 1992-05-26
FI93219C (fi) 1995-03-10
US4922007A (en) 1990-05-01
DE69023280D1 (de) 1995-12-07
ES2080116T3 (es) 1996-02-01
EP0402152B1 (en) 1995-11-02
ATE129713T1 (de) 1995-11-15

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