DK0410207T3 - Stabilisering af højrensede proteiner. - Google Patents

Stabilisering af højrensede proteiner.

Info

Publication number: DK0410207T3
Authority: DK; Denmark
Prior art keywords: protein; stabilization; highly purified; purified proteins; carbohydrate
Prior art date: 1989-07-24

Application number

DK90113210.0T

Other languages

Danish (da)

English (en)

Inventor

Michael H Coan

Vivian W Lee

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-24

Filing date

1990-07-11

Publication date

1997-07-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23517903&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0410207(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-07-11 Application filed by Bayer Ag filed Critical Bayer Ag

1997-07-14 Application granted granted Critical

1997-07-14 Publication of DK0410207T3 publication Critical patent/DK0410207T3/da

Links

102000004169 proteins and genes Human genes 0.000 title abstract 5
108090000623 proteins and genes Proteins 0.000 title abstract 5
230000006641 stabilisation Effects 0.000 title 1
238000011105 stabilization Methods 0.000 title 1
150000001720 carbohydrates Chemical class 0.000 abstract 3
238000000746 purification Methods 0.000 abstract 2
FZWBNHMXJMCXLU-UHFFFAOYSA-N 2,3,4,5-tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal Chemical compound OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OCC(O)C(O)C(O)C(O)C=O)O1 FZWBNHMXJMCXLU-UHFFFAOYSA-N 0.000 abstract 1
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
102000001690 Factor VIII Human genes 0.000 abstract 1
108010054218 Factor VIII Proteins 0.000 abstract 1
229930195725 Mannitol Natural products 0.000 abstract 1
229940119743 dextran 70 Drugs 0.000 abstract 1
229960000301 factor viii Drugs 0.000 abstract 1
238000004108 freeze drying Methods 0.000 abstract 1
235000010355 mannitol Nutrition 0.000 abstract 1
239000000594 mannitol Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Hematology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK90113210.0T 1989-07-24 1990-07-11 Stabilisering af højrensede proteiner. DK0410207T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US38458489A	1989-07-24	1989-07-24

Publications (1)

Publication Number	Publication Date
DK0410207T3 true DK0410207T3 (da)	1997-07-14

Family

ID=23517903

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90113210.0T DK0410207T3 (da)	1989-07-24	1990-07-11	Stabilisering af højrensede proteiner.

Country Status (8)

Country	Link
EP (1)	EP0410207B1 (fr)
JP (1)	JPH0358998A (fr)
AT (1)	ATE148165T1 (fr)
CA (1)	CA2021452A1 (fr)
DE (1)	DE69029765T2 (fr)
DK (1)	DK0410207T3 (fr)
ES (1)	ES2097120T3 (fr)
GR (1)	GR3022614T3 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6165467A (en) *	1991-07-20	2000-12-26	Yoshihide Hagiwara	Stabilized human monoclonal antibody preparation
JP2966592B2 (ja) *	1991-07-20	1999-10-25	萩原義秀	安定化されたヒトモノクローナル抗体製剤
US6270723B1 (en) *	1998-06-15	2001-08-07	Bbi Bioseq, Inc.	Rapid cryobaric sterilization and vaccine preparation
CA2634663C (fr)	1999-02-22	2009-08-25	University Of Connecticut	Nouvelles formulations de facteur viii sans albumine
DE60041363D1 (de)	1999-07-14	2009-02-26	Spectral Diagnostics Inc	Präparierung von sphären für diagnostische tests
HU228583B1 (en)	2000-11-07	2013-04-29	Novartis Vaccines & Diagnostic	Stabilized interferon compositions
US6887462B2 (en)	2001-04-09	2005-05-03	Chiron Corporation	HSA-free formulations of interferon-beta
DE60215823T2 (de) *	2001-08-07	2007-09-06	Novozymes A/S	Kohlhydrate und polyole zum lösen der proteinkristalle
KR20030060660A (ko) *	2002-01-10	2003-07-16	손정일	앞/뒷면 구별 없는 양면 양말
WO2004007520A2 (fr) *	2002-07-12	2004-01-22	Medarex, Inc.	Procedes et compositions visant a prevenir la degradation oxydative de proteines
JP2008501639A (ja) *	2004-04-23	2008-01-24	ノベシンリミテッド	タンパク質を安定化、保護及び可溶化させるための方法及びキット
AU2005235800B2 (en) *	2004-04-23	2011-08-04	Expedeon Limited	Methods and kits for stabilising, protecting and solubilising proteins
CN101605532A (zh) *	2007-02-16	2009-12-16	惠氏公司	含有山梨糖醇的蛋白质调配物
WO2009140162A1 (fr) *	2008-05-15	2009-11-19	Baxter International Inc.	Formulations pharmaceutiques stables
EP2385825B1 (fr)	2008-11-07	2018-10-10	University of Connecticut	Formulation de facteur viii
CN103269716B (zh)	2010-12-02	2015-05-27	昂科利蒂克斯生物科技公司	冻干病毒制剂
WO2012075379A2 (fr)	2010-12-02	2012-06-07	Oncolytics Biotech Inc.	Formulations de virus liquides
MX337348B (es) *	2011-04-29	2016-02-29	Oncolytics Biotech Inc	Metodos para purificar virus utilizando cromatografia de permeacion en gel.
JP6516829B2 (ja)	2014-08-04	2019-05-22	シーエスエル、リミテッド	第ｖｉｉｉ因子製剤
KR20220029733A (ko)	2019-07-04	2022-03-08	체에스엘 베링 렝나우 아게	응고 인자 viii의 시험관내 안정성을 증가시키기 위한 절단된 폰 빌레브란트 인자 (vwf)
EP4240757A2 (fr)	2020-11-09	2023-09-13	Takeda Pharmaceutical Company Limited	Purification de fviii à partir du plasma au moyen d'une adsorption d'oxyde de silicium

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4743680A (en) *	1985-02-01	1988-05-10	New York University	Method for purifying antihemophilic factor
JPH0387173A (ja) *	1987-09-10	1991-04-11	Teijin Ltd	ヒト活性化天然型ファクター８ｃの製造方法及びそれに用いる形質転換体
CA1329760C (fr) *	1987-10-29	1994-05-24	Ted C. K. Lee	Formulation de plasma et de proteines recombinantes dans des milieux a grande force ionique

1990
- 1990-07-11 EP EP90113210A patent/EP0410207B1/fr not_active Revoked
- 1990-07-11 AT AT90113210T patent/ATE148165T1/de active
- 1990-07-11 ES ES90113210T patent/ES2097120T3/es not_active Expired - Lifetime
- 1990-07-11 DK DK90113210.0T patent/DK0410207T3/da active
- 1990-07-11 DE DE69029765T patent/DE69029765T2/de not_active Revoked
- 1990-07-18 CA CA002021452A patent/CA2021452A1/fr not_active Abandoned
- 1990-07-20 JP JP2190898A patent/JPH0358998A/ja active Pending
1997
- 1997-02-19 GR GR970400303T patent/GR3022614T3/el unknown

Also Published As

Publication number	Publication date
GR3022614T3 (en)	1997-05-31
JPH0358998A (ja)	1991-03-14
DE69029765T2 (de)	1997-05-15
EP0410207B1 (fr)	1997-01-22
CA2021452A1 (fr)	1991-01-25
ES2097120T3 (es)	1997-04-01
EP0410207A3 (en)	1992-01-15
ATE148165T1 (de)	1997-02-15
EP0410207A2 (fr)	1991-01-30
DE69029765D1 (de)	1997-03-06

Publication	Publication Date	Title
ES2097120T3 (es)	1997-04-01	Estabilizacion de proteinas altamente purificadas.
DE3874798D1 (de)	1992-10-29	Therapeutisches proteinagens in form von aerosol.
CA2085750A1 (fr)	1991-12-19	Formulations pharmaceutiques favorisant l'osteogenese
DK0511234T3 (da)	1995-08-21	Stabil injicerbar opløsning af faktor VIII
DE68929453D1 (de)	2003-02-27	Osteogene Vorrichtungen
HU9501276D0 (en)	1995-06-28	Stabile, liophylised composition containing proteins
ATE110704T1 (de)	1994-09-15	Verwendung von kohlenstoffmolekularsieben zur reinigung von chlorfluorkohlenwasserstoffen.
EP0422125A4 (en)	1992-07-08	Platelet blocking peptides
DE59308628D1 (de)	1998-07-09	Verfahren zur Herstellung von Faktor VIII
DE69219622D1 (de)	1997-06-12	Herstellung von optisch aktiven aliphatischen carbonsäuren
ATE73462T1 (de)	1992-03-15	Hirudin-variante, deren verwendung und herstellung.
ATE95564T1 (de)	1993-10-15	Aeusseres membranprotein f von pseudomonas aeruginosa.
ATE195877T1 (de)	2000-09-15	Herstellung von faktor-ix
ES2058479T3 (es)	1994-11-01	Compuestos peptidicos.
ATA152093A (de)	1995-07-15	Neue guanidin- und amidinsalze von 7-amino-3-hydroxymethyl-3-cephem-4-carbonsäure
DE69313099D1 (de)	1997-09-18	Herstellung von optisch aktiven aliphatischen carbonsäuren
ES2104686T3 (es)	1997-10-16	Uso de una mezcla de peptidos y aminoacidos en la profilaxis o el tratamiento de la demencia.
ES2062398T3 (es)	1994-12-16	Aroil-ureas.
DE59108261D1 (de)	1996-11-14	Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
DE3888543D1 (de)	1994-04-21	Zusammensetzungen zur herstellung von gasdurchlässigen kontaktlinsen.
DE59203960D1 (de)	1995-11-16	Verfahren zur Herstellung von reinem 3,3',4,4'-Tetraaminobiphenyl.
DE69209855D1 (de)	1996-05-23	Verfahren zur Herstellung von 4,4'-Bis(4-chlorobenzoyl)benzophenon
DK0741746T3 (da)	2006-05-29	Thymosin alpha 1-analoger
DE59307374D1 (de)	1997-10-23	Verfahren zur Herstellung von 5-Halogen-2-(1-anthrachinonylamino)benzoesäuren und 4'-Halogen-2,1(N)-anthrachinonyl-1',2'(N)-benzacridonen
ATE96153T1 (de)	1993-11-15	Gereinigtes protein mit angiogenischer wirkung und dessen herstellung.