DK0437554T3 - Farmaceutisk præparat og fremgangsmåde til inhibering af virus - Google Patents
Farmaceutisk præparat og fremgangsmåde til inhibering af virusInfo
- Publication number
- DK0437554T3 DK0437554T3 DK90908811.4T DK90908811T DK0437554T3 DK 0437554 T3 DK0437554 T3 DK 0437554T3 DK 90908811 T DK90908811 T DK 90908811T DK 0437554 T3 DK0437554 T3 DK 0437554T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutical preparation
- inhibiting viruses
- inhibiting
- butyl
- viruses
- Prior art date
Links
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- UQRORFVVSGFNRO-UTINFBMNSA-N miglustat Chemical compound CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO UQRORFVVSGFNRO-UTINFBMNSA-N 0.000 abstract 1
- 229960001512 miglustat Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000011885 synergistic combination Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/360,439 US5011829A (en) | 1989-06-02 | 1989-06-02 | Pharmaceutical composition and method of inhibiting virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0437554T3 true DK0437554T3 (da) | 1992-12-07 |
Family
ID=23417957
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90908811.4T DK0437554T3 (da) | 1989-06-02 | 1990-05-09 | Farmaceutisk præparat og fremgangsmåde til inhibering af virus |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5011829A (de) |
| EP (2) | EP0437554B1 (de) |
| JP (1) | JPH04500220A (de) |
| AT (1) | ATE81979T1 (de) |
| CA (1) | CA2030803A1 (de) |
| DE (1) | DE69000434T2 (de) |
| DK (1) | DK0437554T3 (de) |
| IE (1) | IE64352B1 (de) |
| PT (1) | PT94247B (de) |
| WO (1) | WO1990014830A1 (de) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5536732A (en) * | 1990-04-27 | 1996-07-16 | Merrell Pharmaceuticals Inc. | N-derivatives of 1-deoxy nojirimycin |
| US5252587A (en) * | 1990-04-27 | 1993-10-12 | Merrell Dow Pharmaceuticals, Inc. | N-derivatives of 1-deoxy nojirimycin |
| EP0547140A4 (en) * | 1990-09-06 | 1993-10-13 | The Australian National University | Immunosuppressant composition |
| AU654152B2 (en) * | 1990-09-06 | 1994-10-27 | Australian National University, The | Immunosuppressant composition |
| WO1992020344A1 (en) * | 1991-05-16 | 1992-11-26 | Glaxo Group Limited | Antiviral combinations containing nucleoside analogs |
| US5258518A (en) * | 1992-04-01 | 1993-11-02 | G. D. Searle & Co. | 2-substituted tertiary carbinol derivatives of deoxynojirimycin |
| US5342951A (en) * | 1992-04-01 | 1994-08-30 | G.D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
| US5216168A (en) * | 1992-04-01 | 1993-06-01 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
| US5268482A (en) * | 1992-04-01 | 1993-12-07 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
| US5206251A (en) * | 1992-04-01 | 1993-04-27 | G. D. Searle & Co. | 2- and 3- amino and azido derivatives of 1,5-iminosugars |
| US5331096A (en) * | 1992-04-01 | 1994-07-19 | G. D. Searle & Co. | 2- and 3-sulfur derivatives of 1,5-iminosugars |
| WO1994004179A1 (en) * | 1992-08-19 | 1994-03-03 | Schering Corporation | Method for inhibiting hiv replication using il-4 |
| US6291657B1 (en) * | 1993-05-13 | 2001-09-18 | Monsanto Company | Deoxygalactonojirimycin derivatives |
| US5399567A (en) * | 1993-05-13 | 1995-03-21 | Monsanto Company | Method of treating cholera |
| US5798366A (en) * | 1993-05-13 | 1998-08-25 | Monsanto Company | Method for treatment of CNS-involved lysosomal storage diseases |
| US5639598A (en) * | 1994-05-19 | 1997-06-17 | The Trustees Of The University Of Pennsylvania | Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions |
| US5780220A (en) * | 1994-05-19 | 1998-07-14 | Trustees Of The University Of Pennsylvania | Methods and compositions for inhibiting HIV replication |
| US20030100532A1 (en) | 1997-02-14 | 2003-05-29 | Gary S. Jacob | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy for treating hepatitis virus infections |
| DK1030839T3 (da) | 1997-11-10 | 2004-05-03 | Searle & Co | Anvendelse af alkylerede iminosukkere til behandling af multidrugresistens |
| US6809083B1 (en) | 1998-02-12 | 2004-10-26 | Richard A. Mueller | Use of N-substituted-1, 5-dideoxy-1, 5-imino-D-glucitol compounds for treating hepatitis virus infections |
| US6689759B1 (en) | 1998-02-12 | 2004-02-10 | G. D. Searle & Co. | Methods of Treating hepatitis virus infections with N-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds in combination therapy |
| WO2001008672A2 (en) | 1999-02-12 | 2001-02-08 | G.D. Searle & Co. | Glucamine compounds for treating hepatitis virus infections |
| JP2002536407A (ja) * | 1999-02-12 | 2002-10-29 | ジー・ディー・サール・アンド・カンパニー | 肝炎ウィルス感染の治療のための置換−1,5−ジデオキシ−1,5−イミノ−d−グルシトール化合物の使用 |
| US6569616B1 (en) * | 1999-07-29 | 2003-05-27 | Wisconsin Alumni Research Foundation | Human cytomegalovirus glycoprotein O as a new drug target and subunit vaccine candidate |
| WO2001060366A1 (en) * | 2000-02-14 | 2001-08-23 | Pharmacia Corporation | Use of n-substituted-1,5-dideoxy-1,5-imino-d-glucitol compounds for treating hepatitis virus infections |
| US7884115B2 (en) * | 2004-09-28 | 2011-02-08 | Allergan, Inc. | Methods and compositions for the treatment of pain and other neurological conditions |
| EP2932982B1 (de) * | 2005-05-17 | 2018-10-03 | Amicus Therapeutics, Inc. | Verfahren zur Behandlung der Pompe-Krankheit mit 1-desoxynojirimycin und Derivaten |
| US8097728B2 (en) * | 2007-04-30 | 2012-01-17 | Philadelphia Health & Education Corporation | Iminosugar compounds with antiflavirus activity |
| KR20200032244A (ko) | 2012-03-07 | 2020-03-25 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 폼페병의 치료를 위한 고농도 알파-글루코시다제 조성물 |
| WO2016054231A1 (en) | 2014-09-30 | 2016-04-07 | Amicus Therapeutics, Inc. | Highly potent acid alpha-glucosidase with enhanced carbohydrates |
| KR102510941B1 (ko) | 2015-12-30 | 2023-03-20 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 폼페병 치료용의 강화된 산 알파-글루코시다제 |
| US10227577B2 (en) | 2016-03-30 | 2019-03-12 | Amicus Therapeutics, Inc. | Method for selection of high M6P recombinant proteins |
| IL325155A (en) | 2016-03-30 | 2026-02-01 | Amicus Therapeutics Inc | Formulations containing recombinant acid alpha-glucosidase |
| EP3624831B1 (de) | 2017-05-15 | 2023-03-29 | Amicus Therapeutics, Inc. | Rekombinante menschliche saure alpha-glucosidase |
| CN109456254B (zh) * | 2018-12-06 | 2020-06-30 | 江西农业大学 | 1-脱氧野尻霉素-羟基查尔酮杂合体衍生物及其制备方法和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4724232A (en) * | 1985-03-16 | 1988-02-09 | Burroughs Wellcome Co. | Treatment of human viral infections |
| US4857511A (en) * | 1985-09-17 | 1989-08-15 | Burroughs Wellcome Co. | Treatment of human viral infections |
| JPS63175354A (ja) * | 1987-01-16 | 1988-07-19 | Shin Kobe Electric Mach Co Ltd | 電池用渦巻電極体の製造装置 |
| EP0282618A1 (de) * | 1987-03-18 | 1988-09-21 | Vereniging Het Nederlands Kanker Instituut | 1-Deoxynojirimycin als Anti-HIV-Therapeutikum |
| US4849430A (en) * | 1988-03-09 | 1989-07-18 | Monsanto Company | Method of inhibiting virus |
-
1989
- 1989-06-02 US US07/360,439 patent/US5011829A/en not_active Expired - Lifetime
-
1990
- 1990-05-09 CA CA002030803A patent/CA2030803A1/en not_active Abandoned
- 1990-05-09 DE DE9090908811T patent/DE69000434T2/de not_active Expired - Fee Related
- 1990-05-09 JP JP2508481A patent/JPH04500220A/ja active Pending
- 1990-05-09 EP EP90908811A patent/EP0437554B1/de not_active Expired - Lifetime
- 1990-05-09 DK DK90908811.4T patent/DK0437554T3/da active
- 1990-05-09 AT AT90908811T patent/ATE81979T1/de active
- 1990-05-09 WO PCT/US1990/002587 patent/WO1990014830A1/en not_active Ceased
- 1990-06-01 IE IE197390A patent/IE64352B1/en not_active IP Right Cessation
- 1990-06-01 PT PT94247A patent/PT94247B/pt not_active IP Right Cessation
- 1990-06-01 EP EP90870085A patent/EP0401194A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IE64352B1 (en) | 1995-07-26 |
| DE69000434T2 (de) | 1993-05-27 |
| PT94247A (pt) | 1991-02-08 |
| DE69000434D1 (de) | 1992-12-10 |
| IE901973L (en) | 1990-12-02 |
| EP0401194A1 (de) | 1990-12-05 |
| US5011829A (en) | 1991-04-30 |
| EP0437554A1 (de) | 1991-07-24 |
| ATE81979T1 (de) | 1992-11-15 |
| JPH04500220A (ja) | 1992-01-16 |
| CA2030803A1 (en) | 1990-12-03 |
| PT94247B (pt) | 1997-05-28 |
| WO1990014830A1 (en) | 1990-12-13 |
| EP0437554B1 (de) | 1992-11-04 |
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