DK0445781T3 - Anti-glaucomapræparater indeholdende 3-arylcarbonyl-1-aminoalkyl-1H-indol - Google Patents

Anti-glaucomapræparater indeholdende 3-arylcarbonyl-1-aminoalkyl-1H-indol

Info

Publication number: DK0445781T3
Authority: DK; Denmark
Prior art keywords: arylcarbonyl; aminoalkyl; indole; preparations containing; glaucoma
Prior art date: 1990-03-08

Application number

DK91103425.4T

Other languages

Danish (da)

English (en)

Inventor

Susan Jean Ward

Malcolm Rice Bell

Original Assignee

Sterling Winthrop Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-08

Filing date

1991-03-06

Publication date

1996-02-19

1991-03-06 Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc

1996-02-19 Application granted granted Critical

1996-02-19 Publication of DK0445781T3 publication Critical patent/DK0445781T3/da

Links

230000001384 anti-glaucoma Effects 0.000 title abstract 2
238000002360 preparation method Methods 0.000 title 1
208000010412 Glaucoma Diseases 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Ophthalmology & Optometry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cosmetics (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK91103425.4T 1990-03-08 1991-03-06 Anti-glaucomapræparater indeholdende 3-arylcarbonyl-1-aminoalkyl-1H-indol DK0445781T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US49020190A	1990-03-08	1990-03-08

Publications (1)

Publication Number	Publication Date
DK0445781T3 true DK0445781T3 (da)	1996-02-19

Family

ID=23947024

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK91103425.4T DK0445781T3 (da)	1990-03-08	1991-03-06	Anti-glaucomapræparater indeholdende 3-arylcarbonyl-1-aminoalkyl-1H-indol

Country Status (21)

Country	Link
EP (1)	EP0445781B1 (fr)
JP (1)	JP3157179B2 (fr)
KR (1)	KR0183396B1 (fr)
AT (1)	ATE133663T1 (fr)
AU (1)	AU643757B2 (fr)
CA (1)	CA2036307C (fr)
DE (1)	DE69116705T2 (fr)
DK (1)	DK0445781T3 (fr)
ES (1)	ES2082872T3 (fr)
FI (1)	FI95369C (fr)
GR (1)	GR3019058T3 (fr)
HU (1)	HU215125B (fr)
IE (1)	IE72953B1 (fr)
IL (1)	IL97426A (fr)
MX (1)	MX174433B (fr)
MY (1)	MY106109A (fr)
NO (1)	NO179612C (fr)
NZ (1)	NZ237309A (fr)
PH (1)	PH27022A (fr)
PT (1)	PT96938B (fr)
RU (1)	RU2073670C1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5068234A (en) *	1990-02-26	1991-11-26	Sterling Drug Inc.	3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
GB9204365D0 (en) *	1992-02-28	1992-04-08	Pfizer Ltd	Indoles
FR2713224B1 (fr) *	1993-12-02	1996-03-01	Sanofi Sa	N-pipéridino-3-pyrazolecarboxamide substitué.
FR2692575B1 (fr) *	1992-06-23	1995-06-30	Sanofi Elf	Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
FR2713225B1 (fr) *	1993-12-02	1996-03-01	Sanofi Sa	N-pipéridino-3-pyrazolecarboxamide substitué.
ES2099007B1 (es) *	1993-07-16	1997-12-01	Pfizer Res & Dev	Derivados de indol.
FR2714057B1 (fr) *	1993-12-17	1996-03-08	Sanofi Elf	Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
ID27812A (id) *	1998-05-01	2001-04-26	Lilly Co Eli	ESTER PENGHAMBAT sPLA2
ATE247963T1 (de) *	1998-05-26	2003-09-15	Pfizer Prod Inc	Medikament zur behandlung von glaukoma und ischämischer retinopathie
WO2001040183A1 (fr) *	1999-12-03	2001-06-07	Alcon Universal Ltd.	1-aminoalkyl-1 h-indoles pour traiter le glaucome
AU771130B2 (en) *	2000-01-18	2004-03-11	Merck & Co., Inc.	Ophthalmic compositions for treating ocular hypertension
WO2001058869A2 (fr) *	2000-02-11	2001-08-16	Bristol-Myers Squibb Company	Modulateurs de recepteurs aux cannabinoides, leurs procedes de preparation et utilisations de modulateurs de recepteurs aux cannabinoides pour le traitement de maladies respiratoires et non respiratoires
TWI231757B (en) *	2001-09-21	2005-05-01	Solvay Pharm Bv	1H-Imidazole derivatives having CB1 agonistic, CB1 partial agonistic or CB1-antagonistic activity
AR038966A1 (es) *	2002-03-18	2005-02-02	Solvay Pharm Bv	Derivados de tiazol que tienen actividad antagonista, agonista o agonista parcial de cb1
SE0203070D0 (en) *	2002-10-16	2002-10-16	Astrazeneca Ab	Novel compounds
TW200508197A (en)	2003-03-31	2005-03-01	Ucb Sa	Indolone-acetamide derivatives, processes for preparing them and their uses
KR20070012389A (ko) *	2004-03-05	2007-01-25	악조 노벨 엔.브이.	칸나비노이드 ｃｂ1 수용체의 아고니스트로서의(인돌-3-일)-헤테로시클 유도체
MX2007011142A (es) *	2005-03-12	2007-11-06	Unilever Nv	Composiciones para el cuidado del cabello y/o cuero cabelludo que incorporan compuestos de amino-oxo-indol-ilideno.
FR2893615B1 (fr) *	2005-11-18	2008-03-07	Sanofi Aventis Sa	Derives de 3-acylindole, leur preparation et leur application en therapeutique
RU2404185C1 (ru) *	2009-04-16	2010-11-20	Учреждение Российской академии наук Институт молекулярной генетики РАН (ИМГ РАН)	РАВНОМЕРНО МЕЧЕННЫЙ ТРИТИЕМ (R)-(+)-[5-МЕТИЛ-3-(4-МОРФОЛИНИЛМЕТИЛ)-2,3-ДИГИДРО-[1,4]ОКСАЗИНО [2,3,4-hi]-6-ИНДОЛИЛ]-1-НАФТАЛИНИЛМЕТАНОН АЦЕТАТ
JP6025234B1 (ja) *	2016-03-10	2016-11-16	株式会社サンライフ	箸における箸置き形成方法及び箸置き機能を有する箸
CN107628981B (zh) *	2017-10-31	2019-07-30	威海市妇女儿童医院	一种肉桂酰基吲哚啉化合物及其制备青光眼药物的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1436771A (en) *	1973-02-16	1976-05-26	Labaz	Indole derivatives and process for preparing the same
US4581354A (en) *	1984-08-06	1986-04-08	Sterling Drug Inc.	3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
US4634776A (en) *	1984-08-06	1987-01-06	Sterling Drug, Inc.	3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles
US4634698A (en) *	1984-09-24	1987-01-06	Schering Corporation	Antiglaucoma agents
DE3821148A1 (de) *	1988-06-23	1989-12-28	Erwin Von Dr Angerer	Aminoalkylindole, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate

1991
- 1991-02-13 CA CA002036307A patent/CA2036307C/fr not_active Expired - Lifetime
- 1991-03-01 IE IE70091A patent/IE72953B1/en not_active IP Right Cessation
- 1991-03-04 IL IL9742691A patent/IL97426A/en not_active IP Right Cessation
- 1991-03-04 PH PH42084A patent/PH27022A/en unknown
- 1991-03-05 HU HU91711A patent/HU215125B/hu unknown
- 1991-03-05 NO NO910868A patent/NO179612C/no not_active IP Right Cessation
- 1991-03-05 NZ NZ237309A patent/NZ237309A/xx unknown
- 1991-03-05 PT PT96938A patent/PT96938B/pt not_active IP Right Cessation
- 1991-03-06 AT AT91103425T patent/ATE133663T1/de not_active IP Right Cessation
- 1991-03-06 FI FI911131A patent/FI95369C/fi active
- 1991-03-06 AU AU72669/91A patent/AU643757B2/en not_active Expired
- 1991-03-06 DK DK91103425.4T patent/DK0445781T3/da active
- 1991-03-06 EP EP91103425A patent/EP0445781B1/fr not_active Expired - Lifetime
- 1991-03-06 ES ES91103425T patent/ES2082872T3/es not_active Expired - Lifetime
- 1991-03-06 DE DE69116705T patent/DE69116705T2/de not_active Expired - Lifetime
- 1991-03-07 MY MYPI91000354A patent/MY106109A/en unknown
- 1991-03-07 KR KR1019910003817A patent/KR0183396B1/ko not_active Expired - Lifetime
- 1991-03-08 JP JP04383191A patent/JP3157179B2/ja not_active Expired - Lifetime
- 1991-03-08 MX MX024839A patent/MX174433B/es unknown
1992
- 1992-05-27 RU SU925011872A patent/RU2073670C1/ru active
1996
- 1996-02-22 GR GR950402831T patent/GR3019058T3/el unknown

Also Published As

Publication number	Publication date
HUT56492A (en)	1991-09-30
FI911131A0 (fi)	1991-03-06
IL97426A (en)	1996-03-31
NO179612C (no)	1996-11-13
NZ237309A (en)	1993-02-25
KR0183396B1 (ko)	1999-05-01
NO910868D0 (no)	1991-03-05
FI911131L (fi)	1991-09-09
PT96938B (pt)	1998-07-31
FI95369B (fi)	1995-10-13
MX24839A (es)	1993-10-01
EP0445781A1 (fr)	1991-09-11
DE69116705D1 (de)	1996-03-14
IL97426A0 (en)	1992-06-21
JPH04235164A (ja)	1992-08-24
GR3019058T3 (en)	1996-05-31
IE910700A1 (en)	1991-09-11
MX174433B (es)	1994-05-16
NO910868L (no)	1991-09-09
HU215125B (hu)	1998-09-28
EP0445781B1 (fr)	1996-01-31
ATE133663T1 (de)	1996-02-15
RU2073670C1 (ru)	1997-02-20
JP3157179B2 (ja)	2001-04-16
CA2036307C (fr)	2002-07-09
CA2036307A1 (fr)	1991-09-09
AU643757B2 (en)	1993-11-25
NO179612B (no)	1996-08-05
FI95369C (fi)	1996-01-25
IE72953B1 (en)	1997-05-07
ES2082872T3 (es)	1996-04-01
KR910016745A (ko)	1991-11-05
DE69116705T2 (de)	1996-09-26
AU7266991A (en)	1991-09-12
MY106109A (en)	1995-03-31
PT96938A (pt)	1991-10-31
PH27022A (en)	1993-02-01

Publication	Publication Date	Title
DK0445781T3 (da)	1996-02-19	Anti-glaucomapræparater indeholdende 3-arylcarbonyl-1-aminoalkyl-1H-indol
ZA907338B (en)	1992-08-26	Thienylcarboxylates of amino alcohols
DE69010139D1 (de)	1994-07-28	Haarkräftigungsmittel.
DK0472327T3 (da)	1995-05-08	Præparat på form af øjendråber
ATE96671T1 (de)	1993-11-15	Verwendung von tetrahydrocortisol in der therapie von glaukom.
DE69106777D1 (de)	1995-03-02	Behandlung von intraokularem Druck mit einer ophthalmischen synergistischen Kombination.
ATE109465T1 (de)	1994-08-15	4-aryl-4-piperidine (oder -pyrrolidin- oder - hexahydroazepin-) carbinole und heterocyclische analoga davon.
IT1240683B (it)	1993-12-17	Composizione farmaceutica contenente egf
DK0437225T3 (da)	1994-06-27	Topiske præparater
ATE98647T1 (de)	1994-01-15	Substituierte thieno(2,3-b) thiophen-2sulfonamide als mittel gegen glaukoma.
FR2483234B2 (fr)	1983-12-23
DK0579939T3 (da)	1999-09-20	Phospholipidderivater
DK0458537T3 (da)	1999-10-18	Anvendelse af en terapeutisk forbindelse til behandling af bronkitis
ATE174911T1 (de)	1999-01-15	1-dimethylcarbamoyl-1h-1,2,4-triazole- substituiert in stellungen 3 und 5
ATE60765T1 (de)	1991-02-15	Pyranderivate.
DE3066521D1 (en)	1984-03-15	Drug for the local treatment of glaucoma
DE69000877D1 (de)	1993-03-18	Augenpraeparate enthaltend timolol maleate.