DK0499541T3 - Fremgangsmåde til oprensning af et kraftigt glycosylerert protein - Google Patents

Fremgangsmåde til oprensning af et kraftigt glycosylerert protein

Info

Publication number
DK0499541T3
DK0499541T3 DK92400381.7T DK92400381T DK0499541T3 DK 0499541 T3 DK0499541 T3 DK 0499541T3 DK 92400381 T DK92400381 T DK 92400381T DK 0499541 T3 DK0499541 T3 DK 0499541T3
Authority
DK
Denmark
Prior art keywords
purification
strong
glycosylated protein
protein
mixture
Prior art date
Application number
DK92400381.7T
Other languages
English (en)
Inventor
Hanno Kolbe
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Application granted granted Critical
Publication of DK0499541T3 publication Critical patent/DK0499541T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/816—Enzyme separation or purification by solubility

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK92400381.7T 1991-02-15 1992-02-13 Fremgangsmåde til oprensning af et kraftigt glycosylerert protein DK0499541T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9101830A FR2672895B1 (fr) 1991-02-15 1991-02-15 Procede de purification d'une proteine fortement glycosylee.

Publications (1)

Publication Number Publication Date
DK0499541T3 true DK0499541T3 (da) 1996-12-02

Family

ID=9409766

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92400381.7T DK0499541T3 (da) 1991-02-15 1992-02-13 Fremgangsmåde til oprensning af et kraftigt glycosylerert protein

Country Status (9)

Country Link
US (1) US5276141A (da)
EP (1) EP0499541B1 (da)
JP (1) JP3376430B2 (da)
AT (1) ATE141283T1 (da)
CA (1) CA2061167C (da)
DE (1) DE69212660T2 (da)
DK (1) DK0499541T3 (da)
ES (1) ES2092067T3 (da)
FR (1) FR2672895B1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284874B1 (en) * 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
US5760189A (en) * 1995-06-02 1998-06-02 Genetics Institute, Inc. Protein recovery & purification methods
US5616693A (en) * 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
WO2001000668A1 (en) * 1999-06-25 2001-01-04 American Cyanamid Company Extraction of integral membrane proteins
AU1198701A (en) * 1999-10-13 2001-04-23 Lexicon Genetics Incorporated Novel human membrane proteins
US7777006B2 (en) 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
JP2007535911A (ja) * 2003-12-30 2007-12-13 バハラ バイオテック インターナショナル リミテッド 組換えタンパク質の製造及び精製方法
EP2154149B1 (en) * 2007-05-29 2019-07-10 Xiamen University A truncated l1 protein of human papillomavirus 6
US20160130324A1 (en) 2014-10-31 2016-05-12 Shire Human Genetic Therapies, Inc. C1 Inhibitor Fusion Proteins and Uses Thereof
CN108463243B (zh) 2015-11-19 2022-06-14 夏尔人类遗传性治疗公司 重组人c1酯酶抑制剂及其用途
CA3124773A1 (en) * 2018-12-28 2020-07-02 Transgene M2-defective poxvirus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947324A (en) * 1975-04-21 1976-03-30 G. D. Searle And Co. Method for isolating high purity peroxidase
JPS6098988A (ja) * 1983-11-01 1985-06-01 Chemo Sero Therapeut Res Inst Ｌｐｆ−ｈａの精製法
EP0213099A3 (de) * 1985-08-23 1989-07-19 Cederroth Nordic Aktiebolag Mittel mit antiphlogistischer, immunstimulierender und zytoprotektiver Wirkung, ihre Herstellung und pharmazeutische Verwendungen
US4798886A (en) * 1986-03-24 1989-01-17 Takeda Chemical Industries, Ltd. Mutual separation of proteins
FR2597344B1 (fr) * 1986-04-16 1989-06-23 Merieux Inst Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire.
EP0277043A3 (en) * 1987-01-30 1989-08-23 IMCERA Group Inc. Method for recovering somatotropins from dilute aqueous solution
DE3787654D1 (de) * 1987-12-23 1993-11-04 Immuno Ag Zellulaere amphipatische proteine in aggregierten formen und verfahren zur herstellung und reinigung diese proteine.
US4992372A (en) * 1989-02-02 1991-02-12 Pokora Alexander R Method for removing impurities from peroxidase solutions
US5101014A (en) * 1989-02-10 1992-03-31 United States Of America Process for the purification of a 69,000 da outer membrane protein of Bordetella pertussis

Also Published As

Publication number Publication date
ES2092067T3 (es) 1996-11-16
JPH04312600A (ja) 1992-11-04
US5276141A (en) 1994-01-04
JP3376430B2 (ja) 2003-02-10
DE69212660T2 (de) 1997-03-13
FR2672895A1 (fr) 1992-08-21
CA2061167C (fr) 2002-06-11
FR2672895B1 (fr) 1995-05-12
DE69212660D1 (de) 1996-09-19
EP0499541A1 (fr) 1992-08-19
CA2061167A1 (fr) 1992-08-16
ATE141283T1 (de) 1996-08-15
EP0499541B1 (fr) 1996-08-14

Similar Documents

Publication Publication Date Title
FR2666996B1 (fr) Methode de purification d'un aminoacide utilisant une resine echangeuse d'ions.
DK0824588T3 (da) Inhibitor af IL-6 aktivitet
DK0839196T3 (da) Humant CTLA-8 og anvendelser af CTLA-8-relaterede proteiner
DK0707594T3 (da) Adskillelse af proteiner
DK332684D0 (da) Modificerede protease-inhibitorer samt deres fremstilling og anvendelse
ATE148130T1 (de) Typ-iv-dipeptidyl-aminopeptidase-inhibitoren
MX9304638A (es) Composicion para tratar e inhibir las ulceras gastricas y duodenales.
NO20016007D0 (no) Rekombinant anti-CD40-antistoff og anvendelser derav
DK496489A (da) Fremgangsmaade til stabilisering af proteiner ved tilrettelaeggelse af indbyrdes elektrostatiske paavirkninger ved metalionbindingssteder
DE69830751D1 (de) Polyaromatische Verbindungen zur Behandlung von Herpes-Infektionen
DE69226877D1 (de) Behandlung der hiv-assoziierten immun-thrombopenie purpura
CA2061167A1 (fr) Procede de purification d'une proteine fortement glycosylee
WO2003035679A3 (en) Molecules
DK1908772T3 (da) Polypeptider og polynucleinsyrer af phorphorymonas gingivalis
EP0680316A4 (en) NEW HELMINTHIC PARASITIC PROTEINS.
DK482185D0 (da) Peptider, deres fremstilling og anvendelse som laegemidler
DK0672192T3 (da) Fremgangsmåde til inhibering af virusmorfogenese
DK0546087T3 (da) Proteinstruktur af plantetoksinet gelonin
DK0504307T3 (da) Fremgangsmåde til behandling af septisk shock
DE69133172D1 (de) Bacterin zur Behandlung von Lebernekrose verursacht durch F. Necrophorum
ATE175975T1 (de) Verdrängungschromatographisches verfahren und gereinigtes hämoglobin
DE69526087D1 (de) Or-1, ein wais-rezeptor der nuklearen rezeptoren familie
PT80152A (de) Methode zur behandlung des glaukoms vok
DE3762409D1 (de) Verfahren zur aufarbeitung von abwaessern aus rauchgasreinigungsanlagen.
DE3781368D1 (de) Granulierte trikalziumphosphat-zusammensetzungen, geeignet zur tablettierung durch direkte kompression.