ATE141283T1 - Verfahren zur reinigung eines hochglykosylierten proteins - Google Patents

Verfahren zur reinigung eines hochglykosylierten proteins

Info

Publication number
ATE141283T1
ATE141283T1 AT92400381T AT92400381T ATE141283T1 AT E141283 T1 ATE141283 T1 AT E141283T1 AT 92400381 T AT92400381 T AT 92400381T AT 92400381 T AT92400381 T AT 92400381T AT E141283 T1 ATE141283 T1 AT E141283T1
Authority
AT
Austria
Prior art keywords
purifying
highly glycosylated
glycosylated protein
protein
mixture
Prior art date
Application number
AT92400381T
Other languages
English (en)
Inventor
Hanno Kolbe
Original Assignee
Transgene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene Sa filed Critical Transgene Sa
Application granted granted Critical
Publication of ATE141283T1 publication Critical patent/ATE141283T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/816—Enzyme separation or purification by solubility

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT92400381T 1991-02-15 1992-02-13 Verfahren zur reinigung eines hochglykosylierten proteins ATE141283T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9101830A FR2672895B1 (fr) 1991-02-15 1991-02-15 Procede de purification d'une proteine fortement glycosylee.

Publications (1)

Publication Number Publication Date
ATE141283T1 true ATE141283T1 (de) 1996-08-15

Family

ID=9409766

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92400381T ATE141283T1 (de) 1991-02-15 1992-02-13 Verfahren zur reinigung eines hochglykosylierten proteins

Country Status (9)

Country Link
US (1) US5276141A (de)
EP (1) EP0499541B1 (de)
JP (1) JP3376430B2 (de)
AT (1) ATE141283T1 (de)
CA (1) CA2061167C (de)
DE (1) DE69212660T2 (de)
DK (1) DK0499541T3 (de)
ES (1) ES2092067T3 (de)
FR (1) FR2672895B1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284874B1 (en) * 1994-06-17 2001-09-04 Alpha Therapeutic Corporation Process for separating α1-proteinase inhibitor from cohn fraction IV1 and IV4 paste
US5760189A (en) * 1995-06-02 1998-06-02 Genetics Institute, Inc. Protein recovery & purification methods
US5616693A (en) * 1996-07-01 1997-04-01 Alpha Therapeutic Corporation Process for seperating alpha-1-proteinase inhibitor from COHN IV1 +1V4 paste
DK1189935T3 (da) * 1999-06-25 2009-02-09 Wyeth Corp Ekstraktion af integrale membranproteiner
WO2001027275A1 (en) * 1999-10-13 2001-04-19 Lexicon Genetics Incorporated Novel human membrane proteins
US7777006B2 (en) 2002-12-31 2010-08-17 Csl Behring L.L.C. Method for purification of alpha-1-antitrypsin
JP2007535911A (ja) * 2003-12-30 2007-12-13 バハラ バイオテック インターナショナル リミテッド 組換えタンパク質の製造及び精製方法
EP2154149B1 (de) * 2007-05-29 2019-07-10 Xiamen University Verkürztes l1-protein des humanen papillomavirus 6
US20160130324A1 (en) 2014-10-31 2016-05-12 Shire Human Genetic Therapies, Inc. C1 Inhibitor Fusion Proteins and Uses Thereof
MA43270A (fr) 2015-11-19 2021-06-02 Takeda Pharmaceuticals Co Inhibiteur de la c1 estérase humaine recombinante et ses utilisations
BR112021012630A2 (pt) * 2018-12-28 2022-12-13 Transgene Sa Poxvírus modificado, método para produzir o poxvírus modificado e composição

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947324A (en) * 1975-04-21 1976-03-30 G. D. Searle And Co. Method for isolating high purity peroxidase
JPS6098988A (ja) * 1983-11-01 1985-06-01 Chemo Sero Therapeut Res Inst Ｌｐｆ−ｈａの精製法
EP0213099A3 (de) * 1985-08-23 1989-07-19 Cederroth Nordic Aktiebolag Mittel mit antiphlogistischer, immunstimulierender und zytoprotektiver Wirkung, ihre Herstellung und pharmazeutische Verwendungen
US4798886A (en) * 1986-03-24 1989-01-17 Takeda Chemical Industries, Ltd. Mutual separation of proteins
FR2597344B1 (fr) * 1986-04-16 1989-06-23 Merieux Inst Perfectionnement au procede de purification d'antigenes proteiques de bacteries appartenant au genre bordetella, en vue de l'obtention d'un vaccin acellulaire.
EP0277043A3 (de) * 1987-01-30 1989-08-23 IMCERA Group Inc. Verfahren zum Gewinnen von Somatotropinen aus verdünnten wässerigen Lösungen
EP0321606B1 (de) * 1987-12-23 1993-09-29 IMMUNO Aktiengesellschaft Zelluläre amphipatische Proteine in aggregierten Formen und Verfahren zur Herstellung und Reinigung diese Proteine
US4992372A (en) * 1989-02-02 1991-02-12 Pokora Alexander R Method for removing impurities from peroxidase solutions
US5101014A (en) * 1989-02-10 1992-03-31 United States Of America Process for the purification of a 69,000 da outer membrane protein of Bordetella pertussis

Also Published As

Publication number Publication date
JPH04312600A (ja) 1992-11-04
US5276141A (en) 1994-01-04
ES2092067T3 (es) 1996-11-16
EP0499541B1 (de) 1996-08-14
JP3376430B2 (ja) 2003-02-10
EP0499541A1 (de) 1992-08-19
CA2061167C (fr) 2002-06-11
DE69212660D1 (de) 1996-09-19
DE69212660T2 (de) 1997-03-13
CA2061167A1 (fr) 1992-08-16
FR2672895B1 (fr) 1995-05-12
FR2672895A1 (fr) 1992-08-21
DK0499541T3 (da) 1996-12-02

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee