DK0699755T3 - Fremgangsmåde til opnåelse af modificerede immunglobuliner med reduceret immunogenicitet af variable domæner i et murint antistof, præparater der indeholder disse - Google Patents

Fremgangsmåde til opnåelse af modificerede immunglobuliner med reduceret immunogenicitet af variable domæner i et murint antistof, præparater der indeholder disse

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Publication number
DK0699755T3
DK0699755T3 DK95201752T DK95201752T DK0699755T3 DK 0699755 T3 DK0699755 T3 DK 0699755T3 DK 95201752 T DK95201752 T DK 95201752T DK 95201752 T DK95201752 T DK 95201752T DK 0699755 T3 DK0699755 T3 DK 0699755T3
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DK
Denmark
Prior art keywords
mammalian species
variable domains
compositions containing
chimaeric antibodies
murine antibody
Prior art date
Application number
DK95201752T
Other languages
English (en)
Inventor
Rolando Perez Rodriquez
Josefa Lombardero Valladares
De Acosta Del Rio Cristi Mateo
Original Assignee
Centro Inmunologia Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of DK0699755T3 publication Critical patent/DK0699755T3/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
DK95201752T 1994-06-30 1995-06-27 Fremgangsmåde til opnåelse af modificerede immunglobuliner med reduceret immunogenicitet af variable domæner i et murint antistof, præparater der indeholder disse DK0699755T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU1994080A CU22615A1 (es) 1994-06-30 1994-06-30 Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos

Publications (1)

Publication Number Publication Date
DK0699755T3 true DK0699755T3 (da) 2004-08-30

Family

ID=5459314

Family Applications (1)

Application Number Title Priority Date Filing Date
DK95201752T DK0699755T3 (da) 1994-06-30 1995-06-27 Fremgangsmåde til opnåelse af modificerede immunglobuliner med reduceret immunogenicitet af variable domæner i et murint antistof, præparater der indeholder disse

Country Status (11)

Country Link
US (1) US5712120A (da)
EP (1) EP0699755B1 (da)
JP (1) JP3238049B2 (da)
CN (1) CN1279168C (da)
AT (1) ATE265531T1 (da)
CA (1) CA2153135C (da)
CU (1) CU22615A1 (da)
DE (1) DE69532940T2 (da)
DK (1) DK0699755T3 (da)
ES (1) ES2220918T3 (da)
PT (1) PT699755E (da)

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PT699755E (pt) 2004-09-30
CU22615A1 (es) 2000-02-10
DE69532940D1 (de) 2004-06-03
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CN1133886A (zh) 1996-10-23
CA2153135C (en) 2005-06-07
ES2220918T3 (es) 2004-12-16
ATE265531T1 (de) 2004-05-15
US5712120A (en) 1998-01-27
EP0699755B1 (en) 2004-04-28
CA2153135A1 (en) 1995-12-31
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