DK0708093T3 - Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse - Google Patents

Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse

Info

Publication number: DK0708093T3
Authority: DK; Denmark
Prior art keywords: alkoxy; quinoxalins; preparation; formula; carbonyl
Prior art date: 1994-10-19

Application number

DK95116094T

Other languages

Danish (da)

English (en)

Inventor

Irvin Dr Winkler

Uta-Maria Billhardt-Troughton

Guenther Dr Riess

Joerg-Peter Dr Kleim

Manfred Dr Roesner

Reinhard Dr Kirsch

Christoph Dr Meichsner

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-19

Filing date

1995-10-12

Publication date

2001-04-30

1995-10-12 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2001-04-30 Application granted granted Critical

2001-04-30 Publication of DK0708093T3 publication Critical patent/DK0708093T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Dental Preparations (AREA)
Plural Heterocyclic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Compounds Of Unknown Constitution (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK95116094T 1994-10-19 1995-10-12 Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse DK0708093T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4437406A DE4437406A1 (de)	1994-10-19	1994-10-19	Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number	Publication Date
DK0708093T3 true DK0708093T3 (da)	2001-04-30

Family

ID=6531202

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95116094T DK0708093T3 (da)	1994-10-19	1995-10-12	Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse

Country Status (27)

Country	Link
US (1)	US5723461A (cs)
EP (1)	EP0708093B1 (cs)
JP (1)	JPH08225544A (cs)
KR (1)	KR960014108A (cs)
CN (1)	CN1094930C (cs)
AT (1)	ATE198747T1 (cs)
AU (1)	AU708293B2 (cs)
BR (1)	BR9504456A (cs)
CA (1)	CA2160859A1 (cs)
CZ (1)	CZ271295A3 (cs)
DE (2)	DE4437406A1 (cs)
DK (1)	DK0708093T3 (cs)
ES (1)	ES2154311T3 (cs)
FI (1)	FI954946L (cs)
GR (1)	GR3035673T3 (cs)
HR (1)	HRP950524B1 (cs)
HU (1)	HUT73485A (cs)
IL (1)	IL115641A0 (cs)
MY (1)	MY132057A (cs)
NO (1)	NO306615B1 (cs)
NZ (1)	NZ280258A (cs)
PL (1)	PL184860B1 (cs)
PT (1)	PT708093E (cs)
SI (1)	SI9500329A (cs)
SK (1)	SK128495A3 (cs)
TW (1)	TW328954B (cs)
ZA (1)	ZA958783B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6369057B1 (en) *	1991-04-15	2002-04-09	Aventis Pharma Deutschland Gmbh	Quinoxalines, processes for their preparation and their use
US6015800A (en) *	1997-09-03	2000-01-18	Warner-Lambert Company	Substituted quinoxaline-2-ones as glutamate receptor antagonists
AU9318298A (en) *	1997-11-14	1999-06-07	Warner-Lambert Company	Small molecule intervention in hiv-1 replication
GB9901795D0 (en) *	1999-01-28	1999-03-17	Glaxo Group Ltd	Chemical compounds
GB9911887D0 (en) *	1999-05-21	1999-07-21	Glaxo Group Ltd	Methods and medicaments for post exposure prophylaxis of an hiv infection
US20030114385A1 (en) *	2001-04-27	2003-06-19	Cathers Brian E.	Viral enzyme activated prototoxophores and use of same to treat viral infections
WO2005018531A2 (en) *	2003-08-26	2005-03-03	'chemical Diversity Research Institute', Ltd.	Pharmaceutical compositions, azo-heterocyclic compounds and method for the production and use thereof
US7351709B2 (en) *	2004-06-09	2008-04-01	Wyeth	Estrogen receptor ligands
JP6378171B2 (ja)	2012-04-24	2018-08-22	バーテックスファーマシューティカルズインコーポレイテッドＶｅｒｔｅｘＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃｏｒｐｏｒａｔｅｄ	Ｄｎａ−ｐｋ阻害剤
SI3527563T1 (sl)	2013-03-12	2022-01-31	Vertex Pharmaceuticals Incorporated	Inhibitorji DNA-PK
RU2675270C2 (ru)	2013-10-17	2018-12-18	Вертекс Фармасьютикалз Инкорпорейтед	Сокристаллы и содержащие их фармацевтические композиции
RU2758669C2 (ru)	2016-09-27	2021-11-01	Вертекс Фармасьютикалз Инкорпорейтед	Способ лечения рака с применением сочетания днк-поражающих агентов и ингибиторов днк-пк
AU2022303386A1 (en) *	2021-07-02	2023-12-14	Aldeyra Therapeutics, Inc.	Heterocyclic aldehyde trapping compounds and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT509398E (pt) *	1991-04-15	2002-02-28	Aventis Pharma Gmbh	Quinoxalinas processo para a sua preparacao e sua utilizacao
DE4342024A1 (de) *	1993-12-09	1995-06-14	Hoechst Ag	Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid

1994
- 1994-10-19 DE DE4437406A patent/DE4437406A1/de not_active Withdrawn
1995
- 1995-10-12 DK DK95116094T patent/DK0708093T3/da active
- 1995-10-12 DE DE59508969T patent/DE59508969D1/de not_active Expired - Fee Related
- 1995-10-12 PT PT95116094T patent/PT708093E/pt unknown
- 1995-10-12 AT AT95116094T patent/ATE198747T1/de not_active IP Right Cessation
- 1995-10-12 ES ES95116094T patent/ES2154311T3/es not_active Expired - Lifetime
- 1995-10-12 EP EP95116094A patent/EP0708093B1/de not_active Expired - Lifetime
- 1995-10-15 IL IL11564195A patent/IL115641A0/xx unknown
- 1995-10-16 TW TW084110841A patent/TW328954B/zh active
- 1995-10-17 US US08/544,290 patent/US5723461A/en not_active Expired - Fee Related
- 1995-10-17 FI FI954946A patent/FI954946L/fi unknown
- 1995-10-17 NZ NZ280258A patent/NZ280258A/en unknown
- 1995-10-17 MY MYPI95003112A patent/MY132057A/en unknown
- 1995-10-17 CZ CZ952712A patent/CZ271295A3/cs unknown
- 1995-10-17 AU AU34316/95A patent/AU708293B2/en not_active Ceased
- 1995-10-17 SK SK1284-95A patent/SK128495A3/sk unknown
- 1995-10-18 HU HU9503005A patent/HUT73485A/hu unknown
- 1995-10-18 ZA ZA958783A patent/ZA958783B/xx unknown
- 1995-10-18 CA CA002160859A patent/CA2160859A1/en not_active Abandoned
- 1995-10-18 PL PL95311016A patent/PL184860B1/pl unknown
- 1995-10-18 NO NO954139A patent/NO306615B1/no not_active IP Right Cessation
- 1995-10-18 HR HR950524A patent/HRP950524B1/xx not_active IP Right Cessation
- 1995-10-18 KR KR1019950035876A patent/KR960014108A/ko not_active Abandoned
- 1995-10-18 CN CN95120372A patent/CN1094930C/zh not_active Expired - Fee Related
- 1995-10-19 JP JP7271019A patent/JPH08225544A/ja active Pending
- 1995-10-19 BR BR9504456A patent/BR9504456A/pt not_active IP Right Cessation
- 1995-10-19 SI SI9500329A patent/SI9500329A/sl unknown
2001
- 2001-03-30 GR GR20010400523T patent/GR3035673T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1135483A (zh)	1996-11-13
HUT73485A (en)	1996-08-28
HRP950524A2 (en)	1997-10-31
CN1094930C (zh)	2002-11-27
EP0708093B1 (de)	2001-01-17
EP0708093A1 (de)	1996-04-24
FI954946A7 (fi)	1996-04-20
DE4437406A1 (de)	1996-04-25
SK128495A3 (en)	1996-06-05
DE59508969D1 (de)	2001-02-22
ATE198747T1 (de)	2001-02-15
AU3431695A (en)	1996-05-02
PL311016A1 (en)	1996-04-29
NO306615B1 (no)	1999-11-29
TW328954B (en)	1998-04-01
NO954139D0 (no)	1995-10-18
ES2154311T3 (es)	2001-04-01
AU708293B2 (en)	1999-07-29
HRP950524B1 (en)	2002-06-30
JPH08225544A (ja)	1996-09-03
PL184860B1 (pl)	2003-01-31
ZA958783B (en)	1996-05-09
HK1011988A1 (en)	1999-07-23
BR9504456A (pt)	1997-05-20
US5723461A (en)	1998-03-03
CA2160859A1 (en)	1996-04-20
PT708093E (pt)	2001-06-29
MY132057A (en)	2007-09-28
SI9500329A (en)	1996-04-30
FI954946A0 (fi)	1995-10-17
HU9503005D0 (en)	1995-12-28
GR3035673T3 (en)	2001-06-29
KR960014108A (ko)	1996-05-22
NZ280258A (en)	1997-09-22
NO954139L (no)	1996-04-22
IL115641A0 (en)	1996-01-19
FI954946L (fi)	1996-04-20
CZ271295A3 (en)	1996-08-14

Publication	Publication Date	Title
DK0708093T3 (da)	2001-04-30	Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse
DE68920773D1 (de)	1995-03-09	Chinoloncarbonsäure-Derivate.
ES8301962A1 (es)	1982-11-01	Un procedimiento para la produccion de un derivado de carboslivilo.
EP0493608A4 (en)	1992-08-12	Quinolonecarboxylic acid derivative
ZA888186B (en)	1989-07-26	Quinolinecarboxylic acid derivatives
ES8504741A1 (es)	1985-05-01	Procedimiento para la preparacion de nuevos derivados de pirimidina o s-triacina.
ATE133938T1 (de)	1996-02-15	Indan-1,3-dion und indan-1,2,3-trionderivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung
MX9702203A (es)	1997-06-28	Derivados de pirazolil-pirazol substituidos, procedimientos para su preparacion y su uso como agentes con accion herbicida.
NO20022123L (no)	2002-05-03	Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
NZ324693A (en)	2000-01-28	2-(O-[pyrimidin-4-yl]methylenoxy)phenyl acetic acid derivatives and fungicidal composition
DE3864193D1 (de)	1991-09-19	Substituierte 5-amino-pyrazole und diese enthaltende fungizide.
DE3867563D1 (en)	1992-02-20	2-amino-5-hydroxy-4-pyrimidone.
PL345966A1 (en)	2002-01-14	N-substituted azabicycloheptane derivatives, production and use thereof
GR3024587T3 (en)	1997-12-31	4-amino-2-(hetero)aryl-butanamides useful as 5-ht1a-antagonists
MX9705379A (es)	1997-10-31	Uso de los 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis vasodilatadora.
DK382588A (da)	1989-01-11	Anti-psykotiske sammensaetninger indeholdende dioxopiperidin derivater
ATE91487T1 (de)	1993-07-15	Dibenzodioxazecin- und dibenzodioxaazacycloundecin-derivate.
MX9705390A (es)	1997-10-31	Uso de los 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis de desordenes degenerativos cerebrales.