DK0708093T3 - Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse - Google Patents

Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse

Info

Publication number: DK0708093T3
Authority: DK; Denmark
Prior art keywords: alkoxy; quinoxalins; preparation; formula; carbonyl
Prior art date: 1994-10-19

Application number

DK95116094T

Other languages

Danish (da)

English (en)

Inventor

Irvin Dr Winkler

Uta-Maria Billhardt-Troughton

Guenther Dr Riess

Joerg-Peter Dr Kleim

Manfred Dr Roesner

Reinhard Dr Kirsch

Christoph Dr Meichsner

Original Assignee

Aventis Pharma Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-19

Filing date

1995-10-12

Publication date

2001-04-30

1995-10-12 Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh

2001-04-30 Application granted granted Critical

2001-04-30 Publication of DK0708093T3 publication Critical patent/DK0708093T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Dental Preparations (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Compounds Of Unknown Constitution (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK95116094T 1994-10-19 1995-10-12 Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse DK0708093T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4437406A DE4437406A1 (de)	1994-10-19	1994-10-19	Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number	Publication Date
DK0708093T3 true DK0708093T3 (da)	2001-04-30

Family

ID=6531202

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95116094T DK0708093T3 (da)	1994-10-19	1995-10-12	Quinoxaliner, fremgangsmåde til fremstilling deraf og deres anvendelse

Country Status (27)

Country	Link
US (1)	US5723461A (fr)
EP (1)	EP0708093B1 (fr)
JP (1)	JPH08225544A (fr)
KR (1)	KR960014108A (fr)
CN (1)	CN1094930C (fr)
AT (1)	ATE198747T1 (fr)
AU (1)	AU708293B2 (fr)
BR (1)	BR9504456A (fr)
CA (1)	CA2160859A1 (fr)
CZ (1)	CZ271295A3 (fr)
DE (2)	DE4437406A1 (fr)
DK (1)	DK0708093T3 (fr)
ES (1)	ES2154311T3 (fr)
FI (1)	FI954946A7 (fr)
GR (1)	GR3035673T3 (fr)
HR (1)	HRP950524B1 (fr)
HU (1)	HUT73485A (fr)
IL (1)	IL115641A0 (fr)
MY (1)	MY132057A (fr)
NO (1)	NO306615B1 (fr)
NZ (1)	NZ280258A (fr)
PL (1)	PL184860B1 (fr)
PT (1)	PT708093E (fr)
SI (1)	SI9500329A (fr)
SK (1)	SK128495A3 (fr)
TW (1)	TW328954B (fr)
ZA (1)	ZA958783B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6369057B1 (en) *	1991-04-15	2002-04-09	Aventis Pharma Deutschland Gmbh	Quinoxalines, processes for their preparation and their use
US6015800A (en) *	1997-09-03	2000-01-18	Warner-Lambert Company	Substituted quinoxaline-2-ones as glutamate receptor antagonists
WO1999025327A2 (fr) *	1997-11-14	1999-05-27	Warner-Lambert Company	Intervention de petites molecules dans la replication du vih-1
GB9901795D0 (en) *	1999-01-28	1999-03-17	Glaxo Group Ltd	Chemical compounds
GB9911887D0 (en) *	1999-05-21	1999-07-21	Glaxo Group Ltd	Methods and medicaments for post exposure prophylaxis of an hiv infection
WO2002087500A2 (fr) *	2001-04-27	2002-11-07	Newbiotics, Inc.	Prototoxophores actives par une enzyme virale et leur utilisation dans le traitement des infections virales
WO2005018531A2 (fr) *	2003-08-26	2005-03-03	'chemical Diversity Research Institute', Ltd.	Compositions pharmaceutiques, composes azo-heterocycliques et procedes de fabrication et d'utilisation correspondants
US7351709B2 (en) *	2004-06-09	2008-04-01	Wyeth	Estrogen receptor ligands
SI3459942T1 (sl)	2012-04-24	2021-05-31	Vertex Pharmaceuticals Incorporated	Inhibitorji DNA-PK
HUE041544T2 (hu)	2013-03-12	2019-05-28	Vertex Pharma	DNS-PK inhibitorok
PT3424920T (pt)	2013-10-17	2020-07-07	Vertex Pharma	Co-cristais de (s)-n-metil-8-(1-((2'-metil-[4,5'-bipirimidin]-6-il)amino)propan-2-il)quinolina-4-carboxamida e derivados deuterados dos mesmos como inibidores de adn-pk
JP2019529475A (ja)	2016-09-27	2019-10-17	バーテックスファーマシューティカルズインコーポレイテッドＶｅｒｔｅｘＰｈａｒｍａｃｅｕｔｉｃａｌｓＩｎｃｏｒｐｏｒａｔｅｄ	Ｄｎａ損傷剤とｄｎａ−ｐｋ阻害剤との組合せ物を使用する、がんを処置するための方法
CN117580569A (zh) *	2021-07-02	2024-02-20	奥尔德拉医疗公司	杂环型醛捕获化合物和其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT509398E (pt) *	1991-04-15	2002-02-28	Aventis Pharma Gmbh	Quinoxalinas processo para a sua preparacao e sua utilizacao
DE4342024A1 (de) *	1993-12-09	1995-06-14	Hoechst Ag	Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid

1994
- 1994-10-19 DE DE4437406A patent/DE4437406A1/de not_active Withdrawn
1995
- 1995-10-12 AT AT95116094T patent/ATE198747T1/de not_active IP Right Cessation
- 1995-10-12 ES ES95116094T patent/ES2154311T3/es not_active Expired - Lifetime
- 1995-10-12 DK DK95116094T patent/DK0708093T3/da active
- 1995-10-12 DE DE59508969T patent/DE59508969D1/de not_active Expired - Fee Related
- 1995-10-12 EP EP95116094A patent/EP0708093B1/fr not_active Expired - Lifetime
- 1995-10-12 PT PT95116094T patent/PT708093E/pt unknown
- 1995-10-15 IL IL11564195A patent/IL115641A0/xx unknown
- 1995-10-16 TW TW084110841A patent/TW328954B/zh active
- 1995-10-17 SK SK1284-95A patent/SK128495A3/sk unknown
- 1995-10-17 AU AU34316/95A patent/AU708293B2/en not_active Ceased
- 1995-10-17 US US08/544,290 patent/US5723461A/en not_active Expired - Fee Related
- 1995-10-17 MY MYPI95003112A patent/MY132057A/en unknown
- 1995-10-17 NZ NZ280258A patent/NZ280258A/en unknown
- 1995-10-17 FI FI954946A patent/FI954946A7/fi unknown
- 1995-10-17 CZ CZ952712A patent/CZ271295A3/cs unknown
- 1995-10-18 HR HR950524A patent/HRP950524B1/xx not_active IP Right Cessation
- 1995-10-18 NO NO954139A patent/NO306615B1/no not_active IP Right Cessation
- 1995-10-18 CA CA002160859A patent/CA2160859A1/fr not_active Abandoned
- 1995-10-18 KR KR1019950035876A patent/KR960014108A/ko not_active Abandoned
- 1995-10-18 CN CN95120372A patent/CN1094930C/zh not_active Expired - Fee Related
- 1995-10-18 PL PL95311016A patent/PL184860B1/pl unknown
- 1995-10-18 ZA ZA958783A patent/ZA958783B/xx unknown
- 1995-10-18 HU HU9503005A patent/HUT73485A/hu unknown
- 1995-10-19 JP JP7271019A patent/JPH08225544A/ja active Pending
- 1995-10-19 SI SI9500329A patent/SI9500329A/sl unknown
- 1995-10-19 BR BR9504456A patent/BR9504456A/pt not_active IP Right Cessation
2001
- 2001-03-30 GR GR20010400523T patent/GR3035673T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
CZ271295A3 (en)	1996-08-14
NO306615B1 (no)	1999-11-29
PT708093E (pt)	2001-06-29
SI9500329A (en)	1996-04-30
CN1094930C (zh)	2002-11-27
MY132057A (en)	2007-09-28
GR3035673T3 (en)	2001-06-29
CA2160859A1 (fr)	1996-04-20
PL184860B1 (pl)	2003-01-31
AU708293B2 (en)	1999-07-29
HRP950524B1 (en)	2002-06-30
IL115641A0 (en)	1996-01-19
PL311016A1 (en)	1996-04-29
TW328954B (en)	1998-04-01
JPH08225544A (ja)	1996-09-03
FI954946L (fi)	1996-04-20
NO954139L (no)	1996-04-22
EP0708093A1 (fr)	1996-04-24
BR9504456A (pt)	1997-05-20
KR960014108A (ko)	1996-05-22
EP0708093B1 (fr)	2001-01-17
US5723461A (en)	1998-03-03
FI954946A0 (fi)	1995-10-17
HU9503005D0 (en)	1995-12-28
AU3431695A (en)	1996-05-02
CN1135483A (zh)	1996-11-13
HRP950524A2 (en)	1997-10-31
DE4437406A1 (de)	1996-04-25
HUT73485A (en)	1996-08-28
SK128495A3 (en)	1996-06-05
NO954139D0 (no)	1995-10-18
HK1011988A1 (en)	1999-07-23
ES2154311T3 (es)	2001-04-01
ATE198747T1 (de)	2001-02-15
FI954946A7 (fi)	1996-04-20
ZA958783B (en)	1996-05-09
DE59508969D1 (de)	2001-02-22
NZ280258A (en)	1997-09-22

Publication	Publication Date	Title
DE68920773D1 (de)	1995-03-09	Chinoloncarbonsäure-Derivate.
ES8301962A1 (es)	1982-11-01	Un procedimiento para la produccion de un derivado de carboslivilo.
EP0493608A4 (en)	1992-08-12	Quinolonecarboxylic acid derivative
KR960014108A (ko)	1996-05-22	퀴녹살린, 이의 제조방법 및 이의 용도
DE50005437D1 (en)	2004-04-01	Substituierte thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)one
ZA888186B (en)	1989-07-26	Quinolinecarboxylic acid derivatives
ES8504741A1 (es)	1985-05-01	Procedimiento para la preparacion de nuevos derivados de pirimidina o s-triacina.
ATE133938T1 (de)	1996-02-15	Indan-1,3-dion und indan-1,2,3-trionderivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung
ES8604717A1 (es)	1986-02-16	Procedimiento para la preparacion de nuevos derivados de 3-fenil-4-cianopirrol.
NO20022123L (no)	2002-05-03	Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
NZ324693A (en)	2000-01-28	2-(O-[pyrimidin-4-yl]methylenoxy)phenyl acetic acid derivatives and fungicidal composition
NZ336091A (en)	2000-12-22	Aqueous disinfecting cleaning composition
DE69008466D1 (de)	1994-06-01	Verwendung des 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-Dimethyluracils zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung von Harnwegsverstopfungen.
DE3864193D1 (de)	1991-09-19	Substituierte 5-amino-pyrazole und diese enthaltende fungizide.
IL141009A0 (en)	2002-02-10	N-substituted azabicycloheptane derivatives, production and use thereof
DE69403896D1 (de)	1997-07-24	4-amino-2-(hetero)aryl-butanamide verwenbar als 5-ht1a-antagonisten
AU606701B2 (en)	1991-02-14	Antipsychotic compositions containing dioxopiperidine derivatives
MX9705379A (es)	1997-10-31	Uso de los 3,4-difenil-cromanos para la fabricacion de una composicion farmaceutica para el tratamiento o profilaxis vasodilatadora.
DK0423870T3 (da)	1993-10-11	Dibenzodioxazecin- dibenzodioxaazacycloundecinderivater
ES459473A1 (es)	1978-04-16	Procedimiento para la preparacion de nuevas 9-alcohilamino- eritromicinas.
JO1825B1 (en)	1995-07-05	Therapeutic agents