DK0922040T3 - Fremgangsmåde til fremstilling af mellemprodukter til florfenicol - Google Patents

Fremgangsmåde til fremstilling af mellemprodukter til florfenicol

Info

Publication number: DK0922040T3
Authority: DK; Denmark
Prior art keywords: florfenicol; intermediates; preparation
Prior art date: 1996-08-19

Application number

DK97938263T

Other languages

Danish (da)

English (en)

Inventor

James C Towson

Dhiru B Vashi

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-19

Filing date

1997-08-18

Publication date

2005-04-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24808601&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0922040(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-08-18 Application filed by Schering Corp filed Critical Schering Corp

2005-04-04 Application granted granted Critical

2005-04-04 Publication of DK0922040T3 publication Critical patent/DK0922040T3/da

Links

AYIRNRDRBQJXIF-NXEZZACHSA-N (-)-Florfenicol Chemical compound CS(=O)(=O)C1=CC=C([C@@H](O)[C@@H](CF)NC(=O)C(Cl)Cl)C=C1 AYIRNRDRBQJXIF-NXEZZACHSA-N 0.000 title 1
229960003760 florfenicol Drugs 0.000 title 1
239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK97938263T 1996-08-19 1997-08-18 Fremgangsmåde til fremstilling af mellemprodukter til florfenicol DK0922040T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/699,271 US5663361A (en)	1996-08-19	1996-08-19	Process for preparing intermediates to florfenicol
EP97938263.7A EP0922040B2 (en)	1996-08-19	1997-08-18	Process for preparing intermediates to florfenicol

Publications (1)

Publication Number	Publication Date
DK0922040T3 true DK0922040T3 (da)	2005-04-04

Family

ID=24808601

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97938263T DK0922040T3 (da)	1996-08-19	1997-08-18	Fremgangsmåde til fremstilling af mellemprodukter til florfenicol

Country Status (30)

Country	Link
US (1)	US5663361A (cs)
EP (1)	EP0922040B2 (cs)
JP (1)	JP3274868B2 (cs)
KR (1)	KR100286851B1 (cs)
CN (1)	CN1097583C (cs)
AR (1)	AR008298A1 (cs)
AT (1)	ATE283847T1 (cs)
AU (1)	AU714495B2 (cs)
BR (1)	BR9711318B1 (cs)
CA (1)	CA2264116C (cs)
CO (1)	CO4560550A1 (cs)
CZ (1)	CZ297915B6 (cs)
DE (1)	DE69731835T3 (cs)
DK (1)	DK0922040T3 (cs)
ES (1)	ES2234026T5 (cs)
HU (1)	HU229610B1 (cs)
ID (1)	ID18047A (cs)
IL (1)	IL128574A (cs)
MY (1)	MY115679A (cs)
NO (1)	NO312962B1 (cs)
NZ (1)	NZ334111A (cs)
PE (1)	PE99798A1 (cs)
PL (2)	PL196454B1 (cs)
PT (1)	PT922040E (cs)
SI (1)	SI0922040T1 (cs)
SK (1)	SK286124B6 (cs)
TR (2)	TR199900354T2 (cs)
TW (1)	TW381075B (cs)
WO (1)	WO1998007709A1 (cs)
ZA (1)	ZA977406B (cs)

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CN1173933C (zh) *	2001-06-01	2004-11-03	中国科学院上海有机化学研究所	一种从l型取代苯丝氨酸酯制备d－（－）－苏式1－r－取代苯基－2－二氯乙酰氨基－3－氟－1－丙醇的方法
JP2005538937A (ja) *	2002-03-08	2005-12-22	シェーリング−プラウ，リミテッド	新規なフロルフェニコール型抗生物質
PE20050386A1 (es) *	2003-05-29	2005-06-23	Schering Plough Ltd	Composiciones farmaceuticas de florfenicol
US7439268B2 (en) *	2003-07-18	2008-10-21	Idexx Laboratories	Compositions containing prodrugs of florfenicol and methods of use
US20050049210A1 (en) *	2003-08-27	2005-03-03	Idexx Laboratories, Inc.	Methods for the controlled delivery of pharmacologically active compounds
US7126005B2 (en) *	2003-10-06	2006-10-24	Aurobindo Pharma Limited	Process for preparing florfenicol
PL1776109T3 (pl)	2004-08-13	2009-06-30	Schering Plough Ltd	Farmaceutyczna formulacja zawierająca antybiotyk, triazol i kortykosteroid
MX2007003378A (es)	2004-09-23	2007-05-10	Schering Plough Ltd	Control de parasitos en animales mediante el uso de nuevos derivados de trifluorometansulfonanilida oxima eter.
EP1811841B1 (en) *	2004-11-19	2009-10-28	Schering-Plough Ltd.	Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1h-pyrrol-2-yl) acrylonitrile derivatives
DK1830885T3 (da) *	2004-12-21	2009-01-05	Intervet Int Bv	Injicerbar veterinærmedicinsk sammensætning omfattende florfenicol
MX2007015729A (es) *	2005-06-09	2008-02-21	Schering Plough Ltd	Control de parasitos en animales con derivados de n-[(feniloxi)fenil]-1,1,1-trifluorometansulfonamida y de n[(fenilsulfanil)fenil]-1,1,1-trifluorometansulfonamida.
KR101408596B1 (ko) *	2005-09-07	2014-06-17	엠에스디 인터내셔널 홀딩즈 게엠베하	에스테르 옥사졸린 화합물의 제조 방법 및플로르페니콜로의 이의 전환
US8119667B2 (en) *	2005-12-29	2012-02-21	Schering-Plough Animal Health Corporation	Carbonates of fenicol antibiotics
US7518017B2 (en)	2006-02-17	2009-04-14	Idexx Laboratories	Fenicol compounds and methods synthesizing 2-trifluoroacetamido-3-substituted propiophenone compounds
US20070238700A1 (en) *	2006-04-10	2007-10-11	Winzenberg Kevin N	N-phenyl-1,1,1-trifluoromethanesulfonamide hydrazone derivative compounds and their usage in controlling parasites
EP2091909A1 (en) *	2006-12-13	2009-08-26	Schering-Plough Ltd.	Water-soluble prodrugs of florfenicol and its analogs
CN101600686A (zh) *	2006-12-13	2009-12-09	先灵-普劳有限公司	氯霉素、甲砜霉素及其类似物的水溶性前药
US20090062397A1 (en) *	2007-04-27	2009-03-05	Schering-Plough Animal Health Corporation	Compounds and methods for enhancing solubility of florfenicol and structurally-related antibiotics using cyclodextrins
AU2008260595A1 (en) *	2007-05-30	2008-12-11	Schering-Plough Ltd.	A process for preparing oxazoline-protected aminodiol compounds useful as intermediates to Florfenicol
TWI430995B (zh)	2007-06-26	2014-03-21	Du Pont	萘異唑啉無脊椎有害動物控制劑
HUE037127T2 (hu)	2007-06-27	2018-08-28	Du Pont	Állati károkozó irtására szolgáló eljárás
RU2010106607A (ru) *	2007-07-25	2011-08-27	Интервет Интернэшнл Б.В. (Nl)	Способ получения оксазолидин- и оксазолидинонаминодиолов
US7550625B2 (en) *	2007-10-19	2009-06-23	Idexx Laboratories	Esters of florfenicol
NZ585219A (en) *	2007-11-09	2012-11-30	Intervet Int Bv	Fast release solid formulation, preparation and use thereof
TWI468407B (zh)	2008-02-06	2015-01-11	Du Pont	中離子農藥
JP2011529895A (ja) *	2008-07-30	2011-12-15	インターベツト・インターナシヨナル・ベー・ベー	フロルフェニコール中間体として有用なオキサゾリン保護アミノジオール化合物を調製する方法
KR20120047996A (ko)	2009-08-05	2012-05-14	이 아이 듀폰 디 네모아 앤드 캄파니	메소이온성 살충제
UA110924C2 (uk)	2009-08-05	2016-03-10	Е. І. Дю Пон Де Немур Енд Компані	Мезоіонні пестициди
MX2012001651A (es)	2009-08-05	2012-03-16	Du Pont	Pesticidas mesoionicos.
UA107804C2 (xx)	2009-08-05	2015-02-25	Du Pont	Суміші мезоіонних пестицидів
BRPI1002023A2 (pt)	2010-03-01	2011-10-25	Nanocore Biotecnologia S A	forma farmacêutica sólida de dissolução rápida para tratamento de infecções bacterianas
MA34247B1 (fr)	2010-05-27	2013-05-02	Du Pont	Forme cristalline du 4-[5-[3-chloro-5-(trifluorométhyl) phényl] -4,5-dihydro-5-(trifluorométhyl)-3-isoxazolyl]-n-[2-oxo-2-[(2, 2,2-trifluoroéthyl) amino] éthyl]-1-naphtalènecarboxamide
WO2012087630A1 (en)	2010-12-20	2012-06-28	E.I. Du Pont De Nemours And Company	Pyridine and pyrimidine compounds for controlling invertebrate
WO2013158422A1 (en)	2012-04-17	2013-10-24	E. I. Du Pont De Nemours And Company	Heterocyclic compounds for controlling invertebrate pests
CN102911133B (zh) *	2012-10-31	2014-07-02	绍兴民生医药有限公司	(4r,5r)-2-二氯甲基-4,5-二氢-5-(4-甲砜基苯基)-4-恶唑甲醇的纯化方法
CN103254147B (zh) *	2013-04-19	2016-04-06	浙江科技学院	一种d-苏式-2-(二氯甲基)-4,5-二氢-5-[对-（甲砜基）苯基]-4-噁唑甲醇的制备方法
CN106278964B (zh) *	2016-07-31	2018-01-16	浙江润康药业有限公司	氟苯尼考的制备方法
CN106631872A (zh) *	2016-12-13	2017-05-10	浙江普洛家园药业有限公司	一种氟苯尼考类似物中间体的合成方法
CN110272856B (zh) *	2019-05-08	2022-05-03	江南大学	一种表达d-苏氨酸醛缩酶的重组菌及其构建方法与应用
CN117466787B (zh) *	2023-12-28	2024-03-22	山东国邦药业有限公司	一种氟苯尼考中间体的制备方法

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US2759001A (en) *	1952-03-01	1956-08-14	Parke Davis & Co	Process for the production of delta2-oxazolines
US4361557A (en) *	1980-01-28	1982-11-30	Schering Corporation	1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor
EP0677511A3 (en) *	1983-06-02	1996-07-24	Zambon Spa	Intermediates for the production of 1-phenyl-1-hydroxy-2-amino-3-fluoropropane derivatives.
US4876352A (en) *	1988-09-14	1989-10-24	Schering Corporation	Pressurized fluorination of hydroxy alkyl groups
AU5674690A (en) †	1989-05-15	1990-12-18	Schering Corporation	Process for preparing antibacterial compounds and intermediates thereto
ATE115123T1 (de) *	1990-10-25	1994-12-15	Schering Corp	Verfahren zur herstellung von florfenicol, seine analoga und oxazolinzwischenprodukte.

1996
- 1996-08-19 US US08/699,271 patent/US5663361A/en not_active Expired - Lifetime
1997
- 1997-08-15 CO CO97047276A patent/CO4560550A1/es unknown
- 1997-08-15 AR ARP970103736A patent/AR008298A1/es not_active Application Discontinuation
- 1997-08-18 ES ES97938263T patent/ES2234026T5/es not_active Expired - Lifetime
- 1997-08-18 MY MYPI97003778A patent/MY115679A/en unknown
- 1997-08-18 PE PE1997000728A patent/PE99798A1/es not_active Application Discontinuation
- 1997-08-18 JP JP51080598A patent/JP3274868B2/ja not_active Expired - Lifetime
- 1997-08-18 PT PT97938263T patent/PT922040E/pt unknown
- 1997-08-18 BR BRPI9711318-2A patent/BR9711318B1/pt not_active IP Right Cessation
- 1997-08-18 WO PCT/US1997/014205 patent/WO1998007709A1/en not_active Ceased
- 1997-08-18 EP EP97938263.7A patent/EP0922040B2/en not_active Expired - Lifetime
- 1997-08-18 IL IL12857497A patent/IL128574A/en not_active IP Right Cessation
- 1997-08-18 DK DK97938263T patent/DK0922040T3/da active
- 1997-08-18 TR TR1999/00354T patent/TR199900354T2/xx unknown
- 1997-08-18 NZ NZ334111A patent/NZ334111A/en not_active IP Right Cessation
- 1997-08-18 SK SK199-99A patent/SK286124B6/sk not_active IP Right Cessation
- 1997-08-18 AT AT97938263T patent/ATE283847T1/de active
- 1997-08-18 ID IDP972887A patent/ID18047A/id unknown
- 1997-08-18 DE DE69731835T patent/DE69731835T3/de not_active Expired - Lifetime
- 1997-08-18 AU AU40638/97A patent/AU714495B2/en not_active Expired
- 1997-08-18 CN CN97198768A patent/CN1097583C/zh not_active Expired - Lifetime
- 1997-08-18 ZA ZA9707406A patent/ZA977406B/xx unknown
- 1997-08-18 CA CA002264116A patent/CA2264116C/en not_active Expired - Lifetime
- 1997-08-18 PL PL331644A patent/PL196454B1/pl not_active IP Right Cessation
- 1997-08-18 SI SI9730688T patent/SI0922040T1/xx unknown
- 1997-08-18 CZ CZ0054099A patent/CZ297915B6/cs not_active IP Right Cessation
- 1997-08-18 HU HU9904166A patent/HU229610B1/hu unknown
- 1997-08-18 PL PL378741A patent/PL198553B1/pl not_active IP Right Cessation
- 1997-08-18 TR TR2008/00474T patent/TR200800474T2/xx unknown
- 1997-08-19 TW TW086111823A patent/TW381075B/zh not_active IP Right Cessation
1999
- 1999-02-18 KR KR1019997001290A patent/KR100286851B1/ko not_active Expired - Lifetime
- 1999-02-18 NO NO19990756A patent/NO312962B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
HUP9904166A3 (en)	2001-11-28
ATE283847T1 (de)	2004-12-15
EP0922040A1 (en)	1999-06-16
BR9711318A (pt)	1999-08-17
PL196454B1 (pl)	2008-01-31
AR008298A1 (es)	1999-12-29
CA2264116A1 (en)	1998-02-26
NZ334111A (en)	1999-10-28
TR200800474T2 (tr)	2008-04-21
CN1233244A (zh)	1999-10-27
US5663361A (en)	1997-09-02
JP2000501424A (ja)	2000-02-08
NO990756D0 (no)	1999-02-18
EP0922040B1 (en)	2004-12-01
MY115679A (en)	2003-08-30
BR9711318B1 (pt)	2009-01-13
PL198553B1 (pl)	2008-06-30
EP0922040B2 (en)	2013-07-17
SK19999A3 (en)	2000-02-14
CZ297915B6 (cs)	2007-04-25
SI0922040T1 (en)	2005-02-28
PE99798A1 (es)	1998-12-28
IL128574A (en)	2002-04-21
DE69731835D1 (de)	2005-01-05
NO312962B1 (no)	2002-07-22
NO990756L (no)	1999-02-18
ES2234026T3 (es)	2005-06-16
ES2234026T5 (es)	2013-11-12
HUP9904166A2 (hu)	2000-05-28
CA2264116C (en)	2002-07-02
HU229610B1 (en)	2014-03-28
AU714495B2 (en)	2000-01-06
CN1097583C (zh)	2003-01-01
PT922040E (pt)	2005-02-28
ID18047A (id)	1998-02-19
HK1017890A1 (en)	1999-12-03
CZ54099A3 (cs)	1999-07-14
JP3274868B2 (ja)	2002-04-15
TW381075B (en)	2000-02-01
KR20000068178A (ko)	2000-11-25
PL331644A1 (en)	1999-08-02
DE69731835T2 (de)	2005-07-21
WO1998007709A1 (en)	1998-02-26
AU4063897A (en)	1998-03-06
CO4560550A1 (es)	1998-02-10
DE69731835T3 (de)	2013-12-05
SK286124B6 (sk)	2008-04-07
KR100286851B1 (ko)	2001-04-16
ZA977406B (en)	1998-02-18
TR199900354T2 (xx)	1999-05-21
IL128574A0 (en)	2000-01-31

Publication	Publication Date	Title
NO990756L (no)	1999-02-18	FremgangsmÕte for fremstilling av mellomprodukter for florfenikol
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DK0773940T3 (da)	2003-09-15	Fremgangsmåde til syntese af substituerede sulfoxider
DK0770615T3 (da)	2003-07-14	Fremgangsmåde til fremstilling af dihalogenazolopyrimidiner
DK0811682T3 (da)	2004-05-17	Fremgangsmåde til fremstilling af L-lysin
DK0857784T3 (da)	2007-01-15	Fremgangsmåde til fremstilling af L-lysin
DK0854189T3 (da)	2007-01-15	Fremgangsmåde til fremstilling af L-lysin
DK1123284T3 (da)	2003-04-28	Fremgangsmåde til fremstilling af citalopram
DK0754756T3 (da)	2006-03-13	Fremgangsmåde til fremstilling af L-lysin
DK0812845T3 (da)	1999-11-29	Fremgangsmåde til fremstilling af sildenafil
DK1038008T3 (da)	2007-03-12	Fremgangsmåde til fremstilling af EGIII-lignende enzymer
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DK0970939T3 (da)	2003-04-07	Fremgangsmåde til fremstilling af methanol
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