DK1019420T3 - Fremgangsmåder til fremstilling af forbindelsesled på grundlag af platin mellem markører og bioorganiske molekyler til mærkning af bioorganiske molekyler til påvisning af interessante biologiske stoffer - Google Patents

Fremgangsmåder til fremstilling af forbindelsesled på grundlag af platin mellem markører og bioorganiske molekyler til mærkning af bioorganiske molekyler til påvisning af interessante biologiske stoffer

Info

Publication number
DK1019420T3
DK1019420T3 DK96915218T DK96915218T DK1019420T3 DK 1019420 T3 DK1019420 T3 DK 1019420T3 DK 96915218 T DK96915218 T DK 96915218T DK 96915218 T DK96915218 T DK 96915218T DK 1019420 T3 DK1019420 T3 DK 1019420T3
Authority
DK
Denmark
Prior art keywords
bioorganic molecules
platinum
methods
biologicals
labeling
Prior art date
Application number
DK96915218T
Other languages
English (en)
Inventor
Hendrik Jan Houthoff
Jan Reedijk
Tinka Jelsma
Es Remco Maria Van
Den Berg Franciscus Michie Van
Edwin Leo Mario Lempers
Marieke Johanna Bloemink
Original Assignee
Kreatech Biotech Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kreatech Biotech Bv filed Critical Kreatech Biotech Bv
Application granted granted Critical
Publication of DK1019420T3 publication Critical patent/DK1019420T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK96915218T 1995-05-09 1996-05-08 Fremgangsmåder til fremstilling af forbindelsesled på grundlag af platin mellem markører og bioorganiske molekyler til mærkning af bioorganiske molekyler til påvisning af interessante biologiske stoffer DK1019420T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95201197 1995-05-09
PCT/NL1996/000198 WO1996035696A1 (en) 1995-05-09 1996-05-08 Methods for the production of platinum-based linkers between labels and bio-organic molecules, for labelling bio-organic molecules, for detecting biological substances of interest and diagnostic test kits

Publications (1)

Publication Number Publication Date
DK1019420T3 true DK1019420T3 (da) 2003-11-24

Family

ID=8220276

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96915218T DK1019420T3 (da) 1995-05-09 1996-05-08 Fremgangsmåder til fremstilling af forbindelsesled på grundlag af platin mellem markører og bioorganiske molekyler til mærkning af bioorganiske molekyler til påvisning af interessante biologiske stoffer

Country Status (12)

Country Link
EP (1) EP1019420B1 (da)
JP (1) JPH11505533A (da)
AT (1) ATE246696T1 (da)
AU (1) AU724320B2 (da)
CA (1) CA2218815C (da)
DE (1) DE69629403T2 (da)
DK (1) DK1019420T3 (da)
ES (1) ES2205030T3 (da)
MX (1) MX9708590A (da)
NZ (1) NZ307633A (da)
PT (1) PT1019420E (da)
WO (1) WO1996035696A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ334803A (en) * 1996-10-08 2000-05-26 Kreatech Biotechnology Bv Method for labeling nucleotides by reacting a reactive platinum compound having two reactive moieties, a labeled moiety and another moiety of a spacer with a nucleotide
US6410724B1 (en) * 1997-04-07 2002-06-25 Institut Pasteur Diagnostic means useful for predictive assessment of human hepatocellular carcinoma disease (HCC), as well as diagnostic methods using the same
WO1998045304A1 (en) * 1997-04-10 1998-10-15 Kreatech Biotechnology B.V. Trans-platinum compound, and diagnostic kit
EP0870770A1 (en) * 1997-04-10 1998-10-14 Kreatech Biotechnology B.V. A trans-platinum based compound, a diagnostic kit comprising said compound and a method for labeling a bio-organic molecule wherein use is made of said compound
EP1006199A1 (en) 1998-12-03 2000-06-07 Kreatech Biotechnology B.V. Applications with and methods for producing selected interstrand crosslinks in nucleic acid
GB0016836D0 (en) 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (1)
EP1221465A1 (en) * 2001-01-03 2002-07-10 Innosense S.r.l. Symmetric, monofunctionalised polymethine dyes labelling reagents
ATE334230T1 (de) 2001-03-02 2006-08-15 Stratagene California Zusammensetzungen und verfahren mit platinverbindungen zur nukleinsäuremarkierung
DE60131070T2 (de) * 2001-05-28 2008-08-07 Kreatech Biotechnology B.V. Ein Verfahren zur differentiellen Markierung mittels Platin-Komplexen
US7138520B2 (en) 2003-01-13 2006-11-21 Massachusetts Institute Of Technology Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same
WO2005080331A1 (ja) * 2004-02-23 2005-09-01 Tetsuo Nagano 蛍光プローブ
EP1745802A1 (en) 2005-07-20 2007-01-24 Kreatech Biotechnology B.V. Method of conjugating therapeutic compounds to cell targeting moieties via metal complexes
CN101970451A (zh) 2007-07-26 2011-02-09 塞雷公司 高度可见的染色体特异性探针及相关方法
WO2011153354A1 (en) 2010-06-03 2011-12-08 Cellay, Inc. Methods and kits for in situ detection of nucleotide sequences
WO2013048243A1 (en) 2011-09-29 2013-04-04 Apo-T B.V. Multi-specific binding molecules targeting aberrant cells
US9145584B2 (en) 2011-12-12 2015-09-29 Cellay, Inc. Methods and kits for room temperature in situ detection of a target nucleic acid in a biological sample
US10668162B2 (en) 2012-01-06 2020-06-02 Linxis B.V. Method for preparing cell targeting conjugates, and the complexes obtained
CA2860914A1 (en) 2012-01-13 2013-07-18 Apo-T B.V. Aberrant cell-restricted immunoglobulins provided with a toxic moiety
EP2914737B1 (en) 2012-10-31 2017-12-06 Cellay, Inc. Methods and kits for performing in situ hybridization
BR112016010354B1 (pt) 2013-11-07 2019-09-17 Cellay, Inc. Métodos e kits para detectar um carcinoma de próstata e prever prognósticos de doença para cânceres de próstata

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207416A (en) * 1974-09-05 1980-06-10 Engelhard Minerals & Chemicals Corporation Ethylenediamineplatinum(II) 2,4-dioxopyrimidine complexes
JPS56103192A (en) * 1980-01-18 1981-08-18 Yoshinori Kitani Novel platinum complex
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
WO1989004317A1 (fr) * 1987-11-06 1989-05-18 Sagami Chemical Research Center Nouveaux complexes de platine (ii)
US4946954A (en) * 1989-01-17 1990-08-07 Georgetown University Platinum pharmaceutical agents
NL9001639A (nl) * 1990-07-19 1992-02-17 Amc Amsterdam Pt-houdende verbinding, werkwijze voor de bereiding ervan, alsmede toepassing van dergelijke verbindingen.

Also Published As

Publication number Publication date
JPH11505533A (ja) 1999-05-21
MX9708590A (es) 1998-06-30
NZ307633A (en) 2000-01-28
EP1019420B1 (en) 2003-08-06
CA2218815C (en) 2008-05-20
CA2218815A1 (en) 1996-11-14
AU724320B2 (en) 2000-09-14
DE69629403D1 (de) 2003-09-11
ATE246696T1 (de) 2003-08-15
EP1019420A1 (en) 2000-07-19
DE69629403T2 (de) 2004-06-24
ES2205030T3 (es) 2004-05-01
PT1019420E (pt) 2003-12-31
AU5704096A (en) 1996-11-29
WO1996035696A1 (en) 1996-11-14

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