DK1024829T3 - Tolerogene fragmenter af naturlige allergener - Google Patents
Tolerogene fragmenter af naturlige allergenerInfo
- Publication number
- DK1024829T3 DK1024829T3 DK97954496T DK97954496T DK1024829T3 DK 1024829 T3 DK1024829 T3 DK 1024829T3 DK 97954496 T DK97954496 T DK 97954496T DK 97954496 T DK97954496 T DK 97954496T DK 1024829 T3 DK1024829 T3 DK 1024829T3
- Authority
- DK
- Denmark
- Prior art keywords
- fragments
- relates
- allergens
- natural
- epitopes
- Prior art date
Links
- 239000013566 allergen Substances 0.000 title abstract 3
- 239000012634 fragment Substances 0.000 title abstract 3
- 230000003614 tolerogenic effect Effects 0.000 title 1
- 230000002009 allergenic effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 230000017274 T cell anergy Effects 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000000172 allergic effect Effects 0.000 abstract 1
- 208000010668 atopic eczema Diseases 0.000 abstract 1
- 210000003719 b-lymphocyte Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43527—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/35—Allergens
- A61K39/36—Allergens from pollen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Insects & Arthropods (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Water Supply & Treatment (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/NL1997/000598 WO1999022762A1 (fr) | 1997-10-30 | 1997-10-30 | Fragments tolerogenes d'allergenes naturels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1024829T3 true DK1024829T3 (da) | 2009-02-09 |
Family
ID=19866218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97954496T DK1024829T3 (da) | 1997-10-30 | 1997-10-30 | Tolerogene fragmenter af naturlige allergener |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US6350590B1 (fr) |
| EP (2) | EP2042192A3 (fr) |
| JP (1) | JP3790099B2 (fr) |
| AT (1) | ATE417626T1 (fr) |
| AU (1) | AU729589C (fr) |
| BR (1) | BR9714899A (fr) |
| CA (1) | CA2307655C (fr) |
| CZ (1) | CZ302352B6 (fr) |
| DE (1) | DE69739174D1 (fr) |
| DK (1) | DK1024829T3 (fr) |
| ES (1) | ES2319341T3 (fr) |
| HU (1) | HUP0004831A3 (fr) |
| IL (1) | IL135881A0 (fr) |
| PL (1) | PL187544B1 (fr) |
| PT (1) | PT1024829E (fr) |
| WO (1) | WO1999022762A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL187544B1 (pl) * | 1997-10-30 | 2004-07-30 | C B F Leti Sa | Wywołujące tolerancję fragmenty naturalnych alergenów |
| CA2471735A1 (fr) * | 2001-08-29 | 2003-03-13 | Kyogo Itoh | Desensibilisants |
| EP1872792A1 (fr) * | 2006-06-29 | 2008-01-02 | Biotech Tools S.A. | Méthode pour la production d'un allergène hydrolysé |
| EP2224953A1 (fr) * | 2008-01-02 | 2010-09-08 | Biotech Tools S.A. | Formulation pharmaceutique pour préparation d'allergènes |
| CN107320734A (zh) | 2011-04-29 | 2017-11-07 | 西莱克塔生物科技公司 | 从合成纳米载体中控制释放免疫抑制剂 |
| CN105307641A (zh) | 2013-05-03 | 2016-02-03 | 西莱克塔生物科技公司 | 用于降低不期望体液免疫应答的给药组合 |
| EA201790551A1 (ru) | 2014-09-07 | 2017-07-31 | Селекта Байосайенсиз, Инк. | Способы и композиции для ослабления иммунных ответов к пропускающему экзон вирусному трансферному вектору |
| ES2868631T3 (es) | 2016-10-05 | 2021-10-21 | Asit Biotech S A | Prevención de la alergia |
| EP4599848A3 (fr) | 2017-03-11 | 2025-12-03 | Cartesian Therapeutics, Inc. | Procédés et compositions associés à un traitement combiné avec anti-inflammatoires et nanovecteurs synthétiques comprenant un immunosuppresseur |
| US12553041B2 (en) | 2019-06-04 | 2026-02-17 | Cartesian Therapeutics Inc. | Formulations and doses of pegylated uricase |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US150389A (en) | 1874-05-05 | Improvement in combined paper-clips and letter-folders | ||
| GB1282163A (en) | 1969-08-06 | 1972-07-19 | Beecham Group Ltd | Modified allergens and a process for their preparation |
| GB1492973A (en) | 1974-02-16 | 1977-11-23 | Beecham Group Ltd | Process for preparing injectable compositions |
| GB1578348A (en) | 1976-08-17 | 1980-11-05 | Pharmacia Ab | Products and a method for the therapeutic suppression of reaginic antibodies responsible for common allergic |
| US4338297A (en) | 1980-02-19 | 1982-07-06 | Michael Jacob G | Polypeptide active pollen immunosuppressant fraction |
| EP0038154B1 (fr) | 1980-04-15 | 1983-09-21 | Beecham Group Plc | Allergènes modifiés à l'aide de polysarcosines |
| JPS58115120A (ja) | 1981-12-28 | 1983-07-08 | Nippon Oil Co Ltd | ピツチ系炭素繊維の製造方法 |
| ES2013359A6 (es) | 1988-11-04 | 1990-05-01 | Corporacion Biolog Farmaceutic | Procedimiento para la fabricacion de alergenos inmunogenicos polimerizados. |
| NL8900652A (nl) | 1989-03-16 | 1990-10-16 | Leti Lab | Primair-toxische stoffen of allergenen, isoleerbaar uit plantaardig materiaal, alsmede werkwijzen ter bereiding ervan en de toepassing ervan. |
| US5792506A (en) * | 1991-10-12 | 1998-08-11 | The Regents Of The University Of California | Neutralization of food allergens by thioredoxin |
| WO1994006821A1 (fr) * | 1992-09-21 | 1994-03-31 | Laboratorios Leti S.A. | Procede pour la purification d'extraits aqueux contenant des proteines allergenes, extraits que l'on peut obtenir par ce procede et leur utilisation |
| ES2098543T3 (es) * | 1992-09-21 | 1997-05-01 | Leti Lab | Un proceso para la purificacion de extractos acuosos que contienen proteinas alergenicamente activas, extractos obtenibles de acuerdo con este proceso, asi como su uso. |
| JPH10510516A (ja) * | 1994-12-07 | 1998-10-13 | ノボ ノルディスク アクティーゼルスカブ | アレルゲン性を減らしたポリペプチド |
| CZ283615B6 (cs) * | 1996-05-31 | 1998-05-13 | Bioveta, A.S. | Způsob výroby vakcín proti dermatofytózám zvířat a dermatofytických alergenů |
| PL187544B1 (pl) * | 1997-10-30 | 2004-07-30 | C B F Leti Sa | Wywołujące tolerancję fragmenty naturalnych alergenów |
| WO2004031961A1 (fr) | 2002-09-30 | 2004-04-15 | Insignia Solutions Plc | Systeme efficace et procede de mise a jour d'un dispositif de memoire |
-
1997
- 1997-10-30 PL PL97340293A patent/PL187544B1/pl not_active IP Right Cessation
- 1997-10-30 IL IL13588197A patent/IL135881A0/xx unknown
- 1997-10-30 AU AU58833/98A patent/AU729589C/en not_active Ceased
- 1997-10-30 DK DK97954496T patent/DK1024829T3/da active
- 1997-10-30 CZ CZ20001529A patent/CZ302352B6/cs not_active IP Right Cessation
- 1997-10-30 EP EP08171363A patent/EP2042192A3/fr not_active Withdrawn
- 1997-10-30 US US09/530,277 patent/US6350590B1/en not_active Expired - Lifetime
- 1997-10-30 HU HU0004831A patent/HUP0004831A3/hu unknown
- 1997-10-30 JP JP2000518693A patent/JP3790099B2/ja not_active Expired - Fee Related
- 1997-10-30 DE DE69739174T patent/DE69739174D1/de not_active Expired - Lifetime
- 1997-10-30 AT AT97954496T patent/ATE417626T1/de not_active IP Right Cessation
- 1997-10-30 ES ES97954496T patent/ES2319341T3/es not_active Expired - Lifetime
- 1997-10-30 PT PT97954496T patent/PT1024829E/pt unknown
- 1997-10-30 EP EP97954496A patent/EP1024829B1/fr not_active Expired - Lifetime
- 1997-10-30 WO PCT/NL1997/000598 patent/WO1999022762A1/fr not_active Ceased
- 1997-10-30 BR BR9714899-7A patent/BR9714899A/pt not_active Application Discontinuation
- 1997-10-30 CA CA002307655A patent/CA2307655C/fr not_active Expired - Fee Related
-
2001
- 2001-12-04 US US10/000,453 patent/US6660495B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6350590B1 (en) | 2002-02-26 |
| US6660495B2 (en) | 2003-12-09 |
| PT1024829E (pt) | 2009-03-18 |
| ATE417626T1 (de) | 2009-01-15 |
| WO1999022762A1 (fr) | 1999-05-14 |
| EP1024829B1 (fr) | 2008-12-17 |
| PL187544B1 (pl) | 2004-07-30 |
| AU729589B2 (en) | 2001-02-08 |
| AU5883398A (en) | 1999-05-24 |
| EP2042192A3 (fr) | 2009-05-27 |
| EP1024829A1 (fr) | 2000-08-09 |
| CZ302352B6 (cs) | 2011-03-30 |
| IL135881A0 (en) | 2001-05-20 |
| JP3790099B2 (ja) | 2006-06-28 |
| PL340293A1 (en) | 2001-01-29 |
| CZ20001529A3 (cs) | 2000-10-11 |
| US20020086348A1 (en) | 2002-07-04 |
| EP2042192A2 (fr) | 2009-04-01 |
| CA2307655A1 (fr) | 1999-05-14 |
| JP2001521907A (ja) | 2001-11-13 |
| AU729589C (en) | 2001-08-30 |
| BR9714899A (pt) | 2000-08-22 |
| CA2307655C (fr) | 2005-05-24 |
| ES2319341T3 (es) | 2009-05-06 |
| HUP0004831A3 (en) | 2001-09-28 |
| DE69739174D1 (de) | 2009-01-29 |
| HUP0004831A2 (hu) | 2001-05-28 |
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