DK113585D0 - Nye peptider - Google Patents

Nye peptider

Info

Publication number
DK113585D0
DK113585D0 DK113585A DK113585A DK113585D0 DK 113585 D0 DK113585 D0 DK 113585D0 DK 113585 A DK113585 A DK 113585A DK 113585 A DK113585 A DK 113585A DK 113585 D0 DK113585 D0 DK 113585D0
Authority
DK
Denmark
Prior art keywords
insulin
charge
amino acid
neutral
new peptides
Prior art date
Application number
DK113585A
Other languages
Danish (da)
English (en)
Inventor
Jan Markussen
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK113585A priority Critical patent/DK113585D0/da
Publication of DK113585D0 publication Critical patent/DK113585D0/da
Priority to ZA861432A priority patent/ZA861432B/xx
Priority to PH33459A priority patent/PH24260A/en
Priority to DD86287734A priority patent/DD244345A5/de
Priority to DK107086A priority patent/DK158677C/da
Priority to YU34586A priority patent/YU46001B/sh
Priority to NZ215445A priority patent/NZ215445A/xx
Priority to AU54495/86A priority patent/AU612964B2/en
Priority to PT82173A priority patent/PT82173B/pt
Priority to HU861024A priority patent/HU201097B/hu
Priority to DE8686301755T priority patent/DE3685668T2/de
Priority to JP61051586A priority patent/JPS61212598A/ja
Priority to CN198686101489A priority patent/CN86101489A/zh
Priority to ES552879A priority patent/ES8800276A1/es
Priority to NO860920A priority patent/NO172441C/no
Priority to AT86301755T priority patent/ATE77391T1/de
Priority to IL78103A priority patent/IL78103A0/xx
Priority to FI861007A priority patent/FI861007A7/fi
Priority to CS861666A priority patent/CS259536B2/cs
Priority to KR1019860001737A priority patent/KR930007433B1/ko
Priority to EP86301755A priority patent/EP0194864B1/en
Priority to GR860687A priority patent/GR860687B/el
Priority to US07/075,387 priority patent/US4946828A/en
Priority to MYPI87002520A priority patent/MY102102A/en
Priority to US07/424,503 priority patent/US5008241A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK113585A 1985-03-12 1985-03-12 Nye peptider DK113585D0 (da)

Priority Applications (25)

Application Number Priority Date Filing Date Title
DK113585A DK113585D0 (da) 1985-03-12 1985-03-12 Nye peptider
ZA861432A ZA861432B (en) 1985-03-12 1986-02-26 Novel peptides
PH33459A PH24260A (en) 1985-03-12 1986-02-27 Novel peptides
DD86287734A DD244345A5 (de) 1985-03-12 1986-03-10 Neue peptide
DK107086A DK158677C (da) 1985-03-12 1986-03-10 Insulinderivater og anvendelsen deraf, injicerbar oploesning indeholdende insulinderivaterne samt fremgangsmaade til fremstilling af oploesningen.
YU34586A YU46001B (sh) 1985-03-12 1986-03-10 Postupak za dobijanje novih peptida
EP86301755A EP0194864B1 (en) 1985-03-12 1986-03-11 Novel peptides
DE8686301755T DE3685668T2 (de) 1985-03-12 1986-03-11 Peptide.
AT86301755T ATE77391T1 (de) 1985-03-12 1986-03-11 Peptide.
PT82173A PT82173B (pt) 1985-03-12 1986-03-11 Processo para a preparacao de novos peptidos
HU861024A HU201097B (en) 1985-03-12 1986-03-11 Process for producing human insulin derivatives and long-acting pharmaceutical compositions comprising same
NZ215445A NZ215445A (en) 1985-03-12 1986-03-11 Insulin derivatives and pharmaceutical composition
JP61051586A JPS61212598A (ja) 1985-03-12 1986-03-11 インシユリン化合物
CN198686101489A CN86101489A (zh) 1985-03-12 1986-03-11 制备新胰岛素肽及其长效注射液的方法
ES552879A ES8800276A1 (es) 1985-03-12 1986-03-11 Un procedimiento para preparar nuevos derivados de insulina
NO860920A NO172441C (no) 1985-03-12 1986-03-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive insulinforbindelser
AU54495/86A AU612964B2 (en) 1985-03-12 1986-03-11 Insulin derivatives having a charge which is positive compared with the charge of human insulin at neutral pH
IL78103A IL78103A0 (en) 1985-03-12 1986-03-11 Peptides,their preparation and pharmaceutical compositions containing them
FI861007A FI861007A7 (fi) 1985-03-12 1986-03-11 Uusia peptidejä.
CS861666A CS259536B2 (en) 1985-03-12 1986-03-11 Method of insulin's new derivatives production
KR1019860001737A KR930007433B1 (ko) 1985-03-12 1986-03-11 사람 인슈린 펩티드의 제조방법
GR860687A GR860687B (en) 1985-03-12 1986-03-12 Novel peptides
US07/075,387 US4946828A (en) 1985-03-12 1987-07-20 Novel insulin peptides
MYPI87002520A MY102102A (en) 1985-03-12 1987-09-30 Novel peptides
US07/424,503 US5008241A (en) 1985-03-12 1989-10-20 Novel insulin peptides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK113585A DK113585D0 (da) 1985-03-12 1985-03-12 Nye peptider

Publications (1)

Publication Number Publication Date
DK113585D0 true DK113585D0 (da) 1985-03-12

Family

ID=8101410

Family Applications (2)

Application Number Title Priority Date Filing Date
DK113585A DK113585D0 (da) 1985-03-12 1985-03-12 Nye peptider
DK107086A DK158677C (da) 1985-03-12 1986-03-10 Insulinderivater og anvendelsen deraf, injicerbar oploesning indeholdende insulinderivaterne samt fremgangsmaade til fremstilling af oploesningen.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK107086A DK158677C (da) 1985-03-12 1986-03-10 Insulinderivater og anvendelsen deraf, injicerbar oploesning indeholdende insulinderivaterne samt fremgangsmaade til fremstilling af oploesningen.

Country Status (22)

Country Link
EP (1) EP0194864B1 (cs)
JP (1) JPS61212598A (cs)
KR (1) KR930007433B1 (cs)
CN (1) CN86101489A (cs)
AT (1) ATE77391T1 (cs)
AU (1) AU612964B2 (cs)
CS (1) CS259536B2 (cs)
DD (1) DD244345A5 (cs)
DE (1) DE3685668T2 (cs)
DK (2) DK113585D0 (cs)
ES (1) ES8800276A1 (cs)
FI (1) FI861007A7 (cs)
GR (1) GR860687B (cs)
HU (1) HU201097B (cs)
IL (1) IL78103A0 (cs)
MY (1) MY102102A (cs)
NO (1) NO172441C (cs)
NZ (1) NZ215445A (cs)
PH (1) PH24260A (cs)
PT (1) PT82173B (cs)
YU (1) YU46001B (cs)
ZA (1) ZA861432B (cs)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
KR900701842A (ko) * 1988-07-20 1990-12-04 헨리 브뢰늄 인간 인슐린 동족체와 그를 포함하는 제제
DE3827533A1 (de) * 1988-08-13 1990-02-15 Hoechst Ag Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
US5130298A (en) * 1989-05-16 1992-07-14 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
AUPP609198A0 (en) * 1998-09-22 1998-10-15 Curtin University Of Technology Use of non-peptidyl compounds for the treatment of insulin related ailments
US6933272B1 (en) 1998-09-22 2005-08-23 Erik Helmerhorst Use of non-peptidyl compounds for the treatment of insulin related ailments
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
ES2642214T3 (es) 2004-01-21 2017-11-15 Novo Nordisk Health Care Ag Conjugación de péptidos mediante transglutaminasa
US20090074882A1 (en) 2005-12-28 2009-03-19 Novo Nordisk A/S Insulin compositions and method of making a composition
DE102006031955A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
BRPI0907119A2 (pt) * 2008-01-09 2015-07-14 Sanofi Aventis Deutschland Derivados de insulina tendo um perfil de ação de tempo extremamente retardado
DE102008003566A1 (de) * 2008-01-09 2009-07-16 Sanofi-Aventis Deutschland Gmbh Neue Insulinderivate mit extrem verzögertem Zeit-/ Wirkungsprofil
AU2009203809B2 (en) * 2008-01-09 2013-07-25 Sanofi-Aventis Deutschland Gmbh Novel insulin derivatives having an extremely delayed time-action profile
PT3228320T (pt) 2008-10-17 2020-03-26 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
TW201105346A (en) * 2009-07-06 2011-02-16 Sanofi Aventis Deutschland Heat-stable and vibration-stable insulin preparations
KR101853606B1 (ko) 2009-07-06 2018-05-03 사노피-아벤티스 도이칠란트 게엠베하 메티오닌을 함유하는 수성 인슐린 제제
KR101337322B1 (ko) 2009-11-13 2013-12-06 사노피-아벤티스 도이칠란트 게엠베하 Glp-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
DK2498802T3 (en) 2009-11-13 2015-04-13 Sanofi Aventis Deutschland Pharmaceutical composition comprising a GLP-1 agonist, insulin and a methionine
JP6249773B2 (ja) * 2010-05-10 2017-12-20 ノヴォ ノルディスク アー/エス インスリン−亜鉛錯体の調製方法
ES2606554T3 (es) 2010-08-30 2017-03-24 Sanofi-Aventis Deutschland Gmbh Uso de AVE0010 para la fabricación de un medicamento para el tratamiento de la diabetes mellitus de tipo 2
CN102174495A (zh) * 2011-01-20 2011-09-07 马忠仁 一种提取糜胰蛋白酶的方法
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
PL2750699T3 (pl) 2011-08-29 2015-12-31 Sanofi Aventis Deutschland Kombinacja farmaceutyczna do stosowania w kontroli glikemii u pacjentów z cukrzycą typu 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
AU2015359376B2 (en) 2014-12-12 2021-09-09 Sanofi-Aventis Deutschland Gmbh Insulin glargine/lixisenatide fixed ratio formulation
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
DE3326472A1 (de) * 1983-07-22 1985-02-14 Hoechst Ag, 6230 Frankfurt Neue insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat

Also Published As

Publication number Publication date
CN86101489A (zh) 1987-01-21
IL78103A0 (en) 1986-07-31
PT82173B (pt) 1988-07-29
ES8800276A1 (es) 1987-11-01
DE3685668T2 (de) 1993-01-14
DE3685668D1 (en) 1992-07-23
DK107086D0 (da) 1986-03-10
NO172441B (no) 1993-04-13
PH24260A (en) 1990-05-04
NO860920L (no) 1986-09-15
DD244345A5 (de) 1987-04-01
PT82173A (en) 1986-04-01
MY102102A (en) 1992-03-31
FI861007L (fi) 1986-09-13
DK158677C (da) 1990-12-31
NZ215445A (en) 1989-07-27
CS259536B2 (en) 1988-10-14
EP0194864B1 (en) 1992-06-17
CS166686A2 (en) 1987-12-17
YU46001B (sh) 1992-12-21
AU612964B2 (en) 1991-07-25
EP0194864A2 (en) 1986-09-17
ZA861432B (en) 1986-11-26
KR930007433B1 (ko) 1993-08-10
ES552879A0 (es) 1987-11-01
FI861007A7 (fi) 1986-09-13
KR860007288A (ko) 1986-10-10
JPS61212598A (ja) 1986-09-20
YU34586A (en) 1988-10-31
GR860687B (en) 1986-07-11
HUT41052A (en) 1987-03-30
EP0194864A3 (en) 1989-01-11
HU201097B (en) 1990-09-28
FI861007A0 (fi) 1986-03-11
DK158677B (da) 1990-07-02
NO172441C (no) 1993-07-21
AU5449586A (en) 1986-09-18
DK107086A (da) 1986-11-07
ATE77391T1 (de) 1992-07-15

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