DK147437C - Fremgangsmaade til fremstilling af humaninsulin eller threoninb30estere af humaninsulin eller et salt eller kompleks deraf - Google Patents

Fremgangsmaade til fremstilling af humaninsulin eller threoninb30estere af humaninsulin eller et salt eller kompleks deraf

Info

Publication number: DK147437C
Authority: DK; Denmark
Prior art keywords: human insulin; inbesters; threon; salt; complex
Prior art date: 1980-02-11

Application number

DK54081A

Other languages

English (en)

Other versions

DK54081A (da

DK147437B (da

Inventor

Jan Markussen

Original Assignee

Novo Industri As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-02-11

Filing date

1981-02-09

Publication date

1986-12-08

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8095095&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK147437(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1981-02-09 Application filed by Novo Industri As filed Critical Novo Industri As

1981-02-09 Priority to DK54081A priority Critical patent/DK147437C/da

1981-08-12 Publication of DK54081A publication Critical patent/DK54081A/da

1984-08-06 Publication of DK147437B publication Critical patent/DK147437B/da

1986-12-08 Application granted granted Critical

1986-12-08 Publication of DK147437C publication Critical patent/DK147437C/da

Links

101000976075 Homo sapiens Insulin Proteins 0.000 title 2
PBGKTOXHQIOBKM-FHFVDXKLSA-N insulin (human) Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H]1CSSC[C@H]2C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=3C=CC(O)=CC=3)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3C=CC(O)=CC=3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=3NC=NC=3)NC(=O)[C@H](CO)NC(=O)CNC1=O)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O)=O)CSSC[C@@H](C(N2)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)CN)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC=1C=CC=CC=1)C(C)C)C1=CN=CN1 PBGKTOXHQIOBKM-FHFVDXKLSA-N 0.000 title 2
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Toxicology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Diabetes (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Forklifts And Lifting Vehicles (AREA)

DK54081A 1980-02-11 1981-02-09 Fremgangsmaade til fremstilling af humaninsulin eller threoninb30estere af humaninsulin eller et salt eller kompleks deraf DK147437C (da)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK54081A DK147437C (da)	1980-02-11	1981-02-09	Fremgangsmaade til fremstilling af humaninsulin eller threoninb30estere af humaninsulin eller et salt eller kompleks deraf

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
DK57480A DK147109C (da)	1980-02-11	1980-02-11	Fremgangsmaade til fremstilling af humant insulin eller humane insulinestere eller et salt eller kompleks deraf
DK57480		1980-02-11
DK54081A DK147437C (da)	1980-02-11	1981-02-09	Fremgangsmaade til fremstilling af humaninsulin eller threoninb30estere af humaninsulin eller et salt eller kompleks deraf
DK54081		1981-02-09

Publications (3)

Publication Number	Publication Date
DK54081A DK54081A (da)	1981-08-12
DK147437B DK147437B (da)	1984-08-06
DK147437C true DK147437C (da)	1986-12-08

Family

ID=8095095

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK147437D DK147437A (en)	1980-02-11		Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK57480A DK147109C (da)	1980-02-11	1980-02-11	Fremgangsmaade til fremstilling af humant insulin eller humane insulinestere eller et salt eller kompleks deraf
DK54081A DK147437C (da)	1980-02-11	1981-02-09	Fremgangsmaade til fremstilling af humaninsulin eller threoninb30estere af humaninsulin eller et salt eller kompleks deraf

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DK147437D DK147437A (en)	1980-02-11		Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DK57480A DK147109C (da)	1980-02-11	1980-02-11	Fremgangsmaade til fremstilling af humant insulin eller humane insulinestere eller et salt eller kompleks deraf

Country Status (19)

Country	Link
JP (1)	JPS56135452A (da)
AR (1)	AR231277A1 (da)
AU (1)	AU541528B2 (da)
BE (1)	BE887480A (da)
CA (1)	CA1162868A (da)
CH (1)	CH655949A5 (da)
DE (1)	DE3104949C2 (da)
DK (3)	DK147109C (da)
ES (1)	ES499238A0 (da)
FI (1)	FI77876C (da)
GB (1)	GB2069502B (da)
GR (1)	GR73844B (da)
IT (1)	IT1195038B (da)
NL (1)	NL178797C (da)
NO (1)	NO156247C (da)
NZ (1)	NZ196224A (da)
PT (1)	PT72485B (da)
SE (2)	SE427025B (da)
ZA (1)	ZA81898B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK147437A (en)	1980-02-11	1900-01-01		Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3101382A1 (de) *	1981-01-17	1982-09-02	Hoechst Ag, 6000 Frankfurt	"verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"
US4601979A (en) *	1981-09-15	1986-07-22	Nordisk Insulinlaboratorium	Process for preparing human insulin or B-30 esters thereof
DK149824C (da) *	1982-01-22	1987-03-16	Carlsberg Biotechnology Ltd	Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyrer i insuliner
EP0087238A1 (en) *	1982-02-08	1983-08-31	Biogen N.V.	Am improved method for preparing human insulin from non-human insulin
DE3209184A1 (de) *	1982-03-13	1983-09-15	Hoechst Ag, 6230 Frankfurt	Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen
NL8201650A (nl) *	1982-04-21	1983-11-16	Akzo Nv	Semisynthetische bereiding van humane insuline.
EP0367302A3 (en) *	1982-04-23	1991-06-19	Wako Pure Chemical Industries, Ltd.	Process for semi-synthesis of human insulin, water-soluble cross-linked achromobacter protease i for use therein and a process for preparing the same
DK55183D0 (da) *	1983-02-09	1983-02-09	Nordisk Insulinlab	Fremgangsmade til fremstilling af human insulin
DE3334407A1 (de) *	1983-09-23	1985-04-04	Hoechst Ag, 6230 Frankfurt	In position b 30 modifizierte insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DK119785D0 (da) *	1985-03-15	1985-03-15	Nordisk Gentofte	Insulinpraeparat
US5157021A (en) *	1985-03-15	1992-10-20	Novo Nordisk A/S	Insulin derivatives and pharmaceutical preparations containing these derivatives
SE449472B (sv) *	1985-10-15	1987-05-04	Mth Gruppen Ab	Utrustning vid facklager
FI884914A0 (fi) *	1987-02-25	1988-10-24	Novo Industri As	Nya insulinderivat.
DK134189D0 (da) *	1989-03-20	1989-03-20	Nordisk Gentofte	Insulinforbindelser
FI96503C (fi) *	1994-08-26	1996-07-10	Hymatic Ltd Oy	Menetelmä ja laitteisto maston ohjaamiseksi
AU2005209199B2 (en)	2004-01-16	2008-09-11	Biodel Inc.	Sublingual drug delivery device
US20080090753A1 (en)	2004-03-12	2008-04-17	Biodel, Inc.	Rapid Acting Injectable Insulin Compositions
US7713929B2 (en)	2006-04-12	2010-05-11	Biodel Inc.	Rapid acting and long acting insulin combination formulations
US8084420B2 (en)	2005-09-29	2011-12-27	Biodel Inc.	Rapid acting and long acting insulin combination formulations
WO2007121256A2 (en)	2006-04-12	2007-10-25	Biodel, Inc.	Rapid acting and long acting insulin combination formulations
US9060927B2 (en)	2009-03-03	2015-06-23	Biodel Inc.	Insulin formulations for rapid uptake

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK146482C (da) *	1979-04-13	1986-10-06	Shionogi & Co	Fremgangsmaade til fremstilling af et b30-threonin-insulin
DK147437A (en)	1980-02-11	1900-01-01		Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3101382A1 (de) *	1981-01-17	1982-09-02	Hoechst Ag, 6000 Frankfurt	"verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"

0
- DK DK147437D patent/DK147437A/da unknown
1980
- 1980-02-11 DK DK57480A patent/DK147109C/da not_active IP Right Cessation
1981
- 1981-02-09 ES ES499238A patent/ES499238A0/es active Granted
- 1981-02-09 DK DK54081A patent/DK147437C/da not_active IP Right Cessation
- 1981-02-10 GB GB8104114A patent/GB2069502B/en not_active Expired
- 1981-02-10 NO NO810443A patent/NO156247C/no unknown
- 1981-02-10 PT PT72485A patent/PT72485B/pt not_active IP Right Cessation
- 1981-02-10 NZ NZ196224A patent/NZ196224A/en unknown
- 1981-02-10 SE SE8100926A patent/SE427025B/sv not_active IP Right Cessation
- 1981-02-10 FI FI810385A patent/FI77876C/fi not_active IP Right Cessation
- 1981-02-10 JP JP1758081A patent/JPS56135452A/ja active Granted
- 1981-02-10 NL NLAANVRAGE8100624,A patent/NL178797C/xx not_active IP Right Cessation
- 1981-02-10 AR AR284258A patent/AR231277A1/es active
- 1981-02-10 CA CA000370483A patent/CA1162868A/en not_active Expired
- 1981-02-10 IT IT19620/81A patent/IT1195038B/it active
- 1981-02-10 SE SE8100928A patent/SE451143B/sv not_active IP Right Cessation
- 1981-02-11 ZA ZA00810898A patent/ZA81898B/xx unknown
- 1981-02-11 GR GR64097A patent/GR73844B/el unknown
- 1981-02-11 AU AU67180/81A patent/AU541528B2/en not_active Ceased
- 1981-02-11 BE BE6/47396A patent/BE887480A/fr not_active IP Right Cessation
- 1981-02-11 CH CH910/81A patent/CH655949A5/de not_active IP Right Cessation
- 1981-02-11 DE DE3104949A patent/DE3104949C2/de not_active Expired

Also Published As

Publication number	Publication date
AR231277A1 (es)	1984-10-31
AU541528B2 (en)	1985-01-10
ZA81898B (en)	1982-03-31
IT8119620A0 (it)	1981-02-10
SE8100926L (sv)	1982-08-11
DK57480A (da)	1981-08-12
ES8205858A1 (es)	1982-08-01
DK147437A (en)	1900-01-01
ES499238A0 (es)	1982-08-01
IT8119620A1 (it)	1982-08-10
DK54081A (da)	1981-08-12
AU6718081A (en)	1981-08-20
NO810443L (no)	1981-08-12
DE3104949C2 (de)	1984-04-26
NO156247B (no)	1987-05-11
SE8100928L (sv)	1981-08-12
FI810385L (fi)	1981-08-12
CA1162868A (en)	1984-02-28
SE451143B (sv)	1987-09-07
FI77876C (fi)	1989-05-10
DK147109B (da)	1984-04-09
BE887480A (fr)	1981-08-11
SE427025B (sv)	1983-02-28
IT1195038B (it)	1988-09-28
GB2069502B (en)	1984-08-08
FI77876B (fi)	1989-01-31
JPS56135452A (en)	1981-10-22
NO156247C (no)	1987-08-19
NL178797B (nl)	1985-12-16
CH655949A5 (de)	1986-05-30
PT72485B (en)	1982-10-14
PT72485A (en)	1981-03-01
JPH0211240B2 (da)	1990-03-13
NL8100624A (nl)	1981-09-01
GR73844B (da)	1984-05-07
NL178797C (nl)	1986-05-16
GB2069502A (en)	1981-08-26
DK147437B (da)	1984-08-06
NZ196224A (en)	1984-08-24
DE3104949A1 (de)	1981-11-26
DK147109C (da)	1986-12-08

Legal Events

Date	Code	Title	Description
1999-09-27	PBP	Patent lapsed

Publication	Publication Date	Title
DK147437C (da)	1986-12-08	Fremgangsmaade til fremstilling af humaninsulin eller threoninb30estere af humaninsulin eller et salt eller kompleks deraf
DK434381A (da)	1982-04-03	Fremgangsmaade til fremstilling af substituerede imonodicarboxylsyrer
DK417981A (da)	1982-03-23	Fremgangsmaade til fremstilling af 3-aryl-5-isothiazol-derivater
DK149754C (da)	1987-03-23	Analogifremgangsmaade til fremstilling af et dermorphinanalogt tetra-, penta-, hexa- eller heptapeptidderivat eller et farmaceutisk acceptabelt salt deraf
JPS5454422A (en)	1979-04-28	Method of fixing element and cartridge for executing said method
DK343682A (da)	1983-02-04	Fremgangsmaade til fremstilling af thiazolidinylalkylen-piperazin-derivater
DK145033C (da)	1986-08-11	Fremgangsmaade til fremstilling af bloed iscreme
DK155680A (da)	1980-10-14	Fremgangsmaade til fremstilling af human insulin
DK302880A (da)	1981-01-14	Fremgangsmaade til fremstilling af et farmaceutisk praeparat indeholdende en 3-amino1-aryl-2-pyrazolin
DK385980A (da)	1981-03-13	Fremgangsmaade til fremstilling af dna med en basesekvens som koder for humant praeproinsulin
DK212381A (da)	1981-11-15	Fremgangsmaade til fremstilling af polynucleotider
DK158443C (da)	1990-10-08	Fremgangsmaade til stabilisering af et lyophiliseret praeparat indeholdende et alkalimetalsalt af en 7beta-(alfa-carboxy-alfa-arylacetamido)-7alfa-methoxy-3-heterocyklisk thiomethyl-1-dethia-1-oxa-3-cephem-4-carboxylsyre
DK152677C (da)	1988-10-24	Analogifremgangsmaade til fremstilling af 4'-0-tetra-hydropyranyladriamycin eller et ugiftigt syreadditionssalt deraf
DK479981A (da)	1982-05-01	Fremgangsmaade til fremstilling af 3-aryl-3-hydroxyphthalimidiner
DK152752C (da)	1988-09-26	Fremgangsmaade til fremstilling af l-sulpirid
DK546879A (da)	1980-06-27	Fremgangsmaade til rensning af insulin
DK136481A (da)	1981-09-28	Fremgangsmaade til fremstilling af et insulinforstadium
DK231481A (da)	1981-11-28	Fremgangsmaade til fremstilling af diacetonektetogulonsyre
DK331381A (da)	1982-01-25	Fremgangsmaade til fremstilling af 1-klor-1-pmetoxybenzoylformaldoxim-n-metylkarbamat
DK501582A (da)	1983-05-12	Fremgangsmaade til fremstilling af acylcyanider
DK94381A (da)	1981-09-26	Fremgangsmaade til fremstilling af sulfonamidpraeparater
NO151897C (no)	1985-06-26	Fremgangsmaate for fremstilling av et insulin eller en insulinanalog
DK548081A (da)	1982-06-12	Fremgangsmaade til fremstilling af buspiron
DK238081A (da)	1981-12-01	Fremgangsmaade til fremstilling af tetramisolanaloge
DK396582A (da)	1983-03-05	Fremgangsmaade til fremstilling af farmaceutisk praeparat