DK1504098T4 - Fremgangsmåde til molekyulær udvikling in vitro af proteinfunktion - Google Patents

Fremgangsmåde til molekyulær udvikling in vitro af proteinfunktion

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Publication number
DK1504098T4
DK1504098T4 DK03722867.3T DK03722867T DK1504098T4 DK 1504098 T4 DK1504098 T4 DK 1504098T4 DK 03722867 T DK03722867 T DK 03722867T DK 1504098 T4 DK1504098 T4 DK 1504098T4
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Denmark
Prior art keywords
stranded polynucleotide
reaction
population
parent
polynucleotide molecules
Prior art date
Application number
DK03722867.3T
Other languages
English (en)
Other versions
DK1504098T3 (da
Inventor
Christina Furebring
Roland Carlsson
Carl Arne Krister Borrebaeck
Hager Ann-Christin Malmborg
Original Assignee
Alligator Bioscience Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29551433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1504098(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0211369A external-priority patent/GB2388604B/en
Priority claimed from US10/321,195 external-priority patent/US7153655B2/en
Application filed by Alligator Bioscience Ab filed Critical Alligator Bioscience Ab
Application granted granted Critical
Publication of DK1504098T3 publication Critical patent/DK1504098T3/da
Publication of DK1504098T4 publication Critical patent/DK1504098T4/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Ecology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK03722867.3T 2002-05-17 2003-05-16 Fremgangsmåde til molekyulær udvikling in vitro af proteinfunktion DK1504098T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0211369A GB2388604B (en) 2002-05-17 2002-05-17 A method for in vitro molecular evolution of protein function
US10/321,195 US7153655B2 (en) 1998-06-16 2002-12-17 Method for in vitro molecular evolution of protein function involving the use of exonuclease enzyme and two populations of parent polynucleotide sequence
PCT/GB2003/002102 WO2003097834A2 (en) 2002-05-17 2003-05-16 A method for in vitro molecular evolution of protein function

Publications (2)

Publication Number Publication Date
DK1504098T3 DK1504098T3 (da) 2007-06-11
DK1504098T4 true DK1504098T4 (da) 2011-05-23

Family

ID=29551433

Family Applications (2)

Application Number Title Priority Date Filing Date
DK03722867.3T DK1504098T4 (da) 2002-05-17 2003-05-16 Fremgangsmåde til molekyulær udvikling in vitro af proteinfunktion
DK200401821A DK200401821A (da) 2002-05-17 2004-11-23 Fremgangsmåde til in vitro molekylær udvikling af proteinfunktion

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK200401821A DK200401821A (da) 2002-05-17 2004-11-23 Fremgangsmåde til in vitro molekylær udvikling af proteinfunktion

Country Status (10)

Country Link
US (1) US7262012B2 (da)
EP (1) EP1504098B2 (da)
JP (1) JP4372679B2 (da)
AT (1) ATE356871T1 (da)
AU (1) AU2003230027A1 (da)
CA (1) CA2485506C (da)
DE (1) DE60312507T3 (da)
DK (2) DK1504098T4 (da)
ES (1) ES2285118T5 (da)
WO (1) WO2003097834A2 (da)

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CN1309662A (zh) * 1998-07-10 2001-08-22 亚利制药有限公司 葡萄球菌属的趋化性抑制蛋白(chips)及其应用
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EP1586583A3 (en) * 2004-04-16 2005-11-16 Alligator Bioscience AB (publ) Compounds that block C5a complement receptor and their use in therapy
GB2432366B (en) * 2005-11-19 2007-11-21 Alligator Bioscience Ab A method for in vitro molecular evolution of protein function
GB0607798D0 (en) 2006-04-20 2006-05-31 Alligator Bioscience Ab Novel polypeptides and use thereof
GB0708376D0 (en) 2007-05-01 2007-06-06 Alligator Bioscience Ab Novel polypeptides and uses thereof
GB0905790D0 (en) 2009-04-03 2009-05-20 Alligator Bioscience Ab Novel polypeptides and use thereof
GB0905503D0 (en) * 2009-03-31 2009-05-13 Alligator Bioscience Ab A method for in vitro molecular evolution of protein function
GB0920258D0 (en) 2009-11-19 2010-01-06 Alligator Bioscience Ab New medical agents and use thereof
GB201019086D0 (en) 2010-11-11 2010-12-29 Imp Innovations Ltd Bacterial methods
WO2012122135A2 (en) 2011-03-04 2012-09-13 Evolvemol, Inc. Apparatus and process for isolating specific physical items within a set of physical items
GB201115280D0 (en) 2011-09-05 2011-10-19 Alligator Bioscience Ab Antibodies, uses and methods
GB201311475D0 (en) 2013-06-27 2013-08-14 Alligator Bioscience Ab Polypeptides
KR102443258B1 (ko) 2014-08-12 2022-09-14 엘리게이터 바이오사이언스 에이비 항 cd40 항체에 의한 병용 치료제
BR112018006360A2 (pt) 2015-09-30 2018-10-09 Janssen Biotech Inc anticorpos agonísticos que se ligam especificamente ao cd40 humano e métodos de uso
CN113892654A (zh) * 2021-10-21 2022-01-07 长春大学 一种以绿豆蛋白粉为原料制备免消化绿豆蛋白质的方法

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WO2003097834A2 (en) 2003-11-27
JP4372679B2 (ja) 2009-11-25
DK200401821A (da) 2004-11-23
JP2005525820A (ja) 2005-09-02
EP1504098A2 (en) 2005-02-09
ES2285118T5 (es) 2012-09-21
ES2285118T3 (es) 2007-11-16
CA2485506C (en) 2012-02-28
DE60312507T2 (de) 2007-12-06
ATE356871T1 (de) 2007-04-15
CA2485506A1 (en) 2003-11-27
EP1504098B1 (en) 2007-03-14
US20060166198A1 (en) 2006-07-27
AU2003230027A1 (en) 2003-12-02
DK1504098T3 (da) 2007-06-11
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DE60312507D1 (de) 2007-04-26
DE60312507T3 (de) 2011-08-18

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