DK1678129T3 - Forbedret fremgangsmåde til fremstilling af benzhydrylthioacetamid - Google Patents
Forbedret fremgangsmåde til fremstilling af benzhydrylthioacetamidInfo
- Publication number
- DK1678129T3 DK1678129T3 DK04796038T DK04796038T DK1678129T3 DK 1678129 T3 DK1678129 T3 DK 1678129T3 DK 04796038 T DK04796038 T DK 04796038T DK 04796038 T DK04796038 T DK 04796038T DK 1678129 T3 DK1678129 T3 DK 1678129T3
- Authority
- DK
- Denmark
- Prior art keywords
- improved process
- reaction
- benzhydrylthioacetate
- haloacetate
- purity
- Prior art date
Links
- HVWYTOBXSCCZOP-UHFFFAOYSA-N 3,3-diphenylpropanethioamide Chemical compound C=1C=CC=CC=1C(CC(=S)N)C1=CC=CC=C1 HVWYTOBXSCCZOP-UHFFFAOYSA-N 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 abstract 2
- BIASHYVHAQBNGV-UHFFFAOYSA-N 3,3-diphenylpropanethioic s-acid Chemical compound C=1C=CC=CC=1C(CC(=S)O)C1=CC=CC=C1 BIASHYVHAQBNGV-UHFFFAOYSA-N 0.000 abstract 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
- 229960001165 modafinil Drugs 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 150000001447 alkali salts Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- QILSFLSDHQAZET-UHFFFAOYSA-N diphenylmethanol Chemical compound C=1C=CC=CC=1C(O)C1=CC=CC=C1 QILSFLSDHQAZET-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
- 235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51377903P | 2003-10-23 | 2003-10-23 | |
| US55733104P | 2004-03-29 | 2004-03-29 | |
| PCT/US2004/034975 WO2005042479A1 (en) | 2003-10-23 | 2004-10-22 | Improved process for preparing benzhydrylthioacetamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1678129T3 true DK1678129T3 (da) | 2009-02-09 |
Family
ID=34555914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04796038T DK1678129T3 (da) | 2003-10-23 | 2004-10-22 | Forbedret fremgangsmåde til fremstilling af benzhydrylthioacetamid |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7345188B2 (da) |
| EP (1) | EP1678129B1 (da) |
| JP (1) | JP2007509161A (da) |
| AT (1) | ATE410410T1 (da) |
| AU (1) | AU2004285925A1 (da) |
| CA (1) | CA2543326A1 (da) |
| DE (1) | DE602004017036D1 (da) |
| DK (1) | DK1678129T3 (da) |
| ES (1) | ES2314464T3 (da) |
| MX (1) | MXPA06004403A (da) |
| PT (1) | PT1678129E (da) |
| SI (1) | SI1678129T1 (da) |
| WO (1) | WO2005042479A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101326159A (zh) * | 2005-12-09 | 2008-12-17 | 马林克罗特公司 | 制备莫达非尼及其类似物的方法 |
| US7960586B2 (en) | 2007-08-16 | 2011-06-14 | Teva Pharmaceutical Industries Ltd. | Purification of armodafinil |
| PL2985279T3 (pl) | 2014-08-13 | 2018-03-30 | Red Bull Gmbh | Związki heterocykliczne mające działanie poprawiające pamięć roboczą |
| CA2989243C (en) | 2014-08-13 | 2023-03-14 | Red Bull Gmbh | Heterocyclic compounds with working memory enhancing activity |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4098824A (en) * | 1975-10-02 | 1978-07-04 | Laboratoire L. Lafon | Benzhydrylsulphinyl derivatives |
| GB1584462A (en) * | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
| US6875893B2 (en) * | 2002-05-23 | 2005-04-05 | Cephalon, Inc. | Preparations of a sulfinyl acetamide |
| CA2511992A1 (en) * | 2003-02-24 | 2004-09-10 | Mallinckrodt Inc. | Process for preparing benzhydrylthioacetamide |
-
2004
- 2004-10-22 DK DK04796038T patent/DK1678129T3/da active
- 2004-10-22 US US10/570,243 patent/US7345188B2/en not_active Expired - Fee Related
- 2004-10-22 CA CA002543326A patent/CA2543326A1/en not_active Abandoned
- 2004-10-22 AT AT04796038T patent/ATE410410T1/de not_active IP Right Cessation
- 2004-10-22 JP JP2006536808A patent/JP2007509161A/ja not_active Withdrawn
- 2004-10-22 ES ES04796038T patent/ES2314464T3/es not_active Expired - Lifetime
- 2004-10-22 EP EP04796038A patent/EP1678129B1/en not_active Expired - Lifetime
- 2004-10-22 MX MXPA06004403A patent/MXPA06004403A/es active IP Right Grant
- 2004-10-22 DE DE602004017036T patent/DE602004017036D1/de not_active Expired - Fee Related
- 2004-10-22 SI SI200430988T patent/SI1678129T1/sl unknown
- 2004-10-22 PT PT04796038T patent/PT1678129E/pt unknown
- 2004-10-22 AU AU2004285925A patent/AU2004285925A1/en not_active Abandoned
- 2004-10-22 WO PCT/US2004/034975 patent/WO2005042479A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATE410410T1 (de) | 2008-10-15 |
| DE602004017036D1 (de) | 2008-11-20 |
| MXPA06004403A (es) | 2006-07-06 |
| CA2543326A1 (en) | 2005-05-12 |
| WO2005042479A1 (en) | 2005-05-12 |
| AU2004285925A1 (en) | 2005-05-12 |
| US7345188B2 (en) | 2008-03-18 |
| SI1678129T1 (sl) | 2009-10-31 |
| EP1678129B1 (en) | 2008-10-08 |
| US20080027240A1 (en) | 2008-01-31 |
| PT1678129E (pt) | 2008-11-26 |
| ES2314464T3 (es) | 2009-03-16 |
| JP2007509161A (ja) | 2007-04-12 |
| EP1678129A1 (en) | 2006-07-12 |
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