ATE410410T1 - Verbessertes verfahren zur herstellung von benzhydrylthioacetamid. - Google Patents

Verbessertes verfahren zur herstellung von benzhydrylthioacetamid.

Info

Publication number: ATE410410T1
Authority: AT; Austria
Prior art keywords: benzhydrylthioacetamide; producing; reaction; improved method; benzhydrylthioacetate
Prior art date: 2003-10-23

Application number

AT04796038T

Other languages

English (en)

Inventor

Sidney Liang

Original Assignee

Mallinckrodt Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-10-23

Filing date

2004-10-22

Publication date

2008-10-15

2004-10-22 Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc

2008-10-15 Application granted granted Critical

2008-10-15 Publication of ATE410410T1 publication Critical patent/ATE410410T1/de

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
HVWYTOBXSCCZOP-UHFFFAOYSA-N 3,3-diphenylpropanethioamide Chemical compound C=1C=CC=CC=1C(CC(=S)N)C1=CC=CC=C1 HVWYTOBXSCCZOP-UHFFFAOYSA-N 0.000 title 1
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 abstract 2
BIASHYVHAQBNGV-UHFFFAOYSA-N 3,3-diphenylpropanethioic s-acid Chemical compound C=1C=CC=CC=1C(CC(=S)O)C1=CC=CC=C1 BIASHYVHAQBNGV-UHFFFAOYSA-N 0.000 abstract 2
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
229960001165 modafinil Drugs 0.000 abstract 2
UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
150000001447 alkali salts Chemical class 0.000 abstract 1
239000007795 chemical reaction product Substances 0.000 abstract 1
QILSFLSDHQAZET-UHFFFAOYSA-N diphenylmethanol Chemical compound C=1C=CC=CC=1C(O)C1=CC=CC=C1 QILSFLSDHQAZET-UHFFFAOYSA-N 0.000 abstract 1
150000007530 organic bases Chemical class 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cephalosporin Compounds (AREA)

AT04796038T 2003-10-23 2004-10-22 Verbessertes verfahren zur herstellung von benzhydrylthioacetamid. ATE410410T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US51377903P	2003-10-23	2003-10-23
US55733104P	2004-03-29	2004-03-29

Publications (1)

Publication Number	Publication Date
ATE410410T1 true ATE410410T1 (de)	2008-10-15

Family

ID=34555914

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04796038T ATE410410T1 (de)	2003-10-23	2004-10-22	Verbessertes verfahren zur herstellung von benzhydrylthioacetamid.

Country Status (13)

Country	Link
US (1)	US7345188B2 (de)
EP (1)	EP1678129B1 (de)
JP (1)	JP2007509161A (de)
AT (1)	ATE410410T1 (de)
AU (1)	AU2004285925A1 (de)
CA (1)	CA2543326A1 (de)
DE (1)	DE602004017036D1 (de)
DK (1)	DK1678129T3 (de)
ES (1)	ES2314464T3 (de)
MX (1)	MXPA06004403A (de)
PT (1)	PT1678129E (de)
SI (1)	SI1678129T1 (de)
WO (1)	WO2005042479A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1973873A2 (de) *	2005-12-09	2008-10-01	Mallinckrodt Inc.	Verfahren zur herstellung von modafinil und analoga davon
US7960586B2 (en)	2007-08-16	2011-06-14	Teva Pharmaceutical Industries Ltd.	Purification of armodafinil
EP2985279B1 (de)	2014-08-13	2017-08-02	Red Bull GmbH	Heterocyclische Verbindungen mit Aktivität zur Arbeitsspeicherverbesserung
WO2016023997A1 (en)	2014-08-13	2016-02-18	Red Bull Gmbh	Heterocyclic compounds with working memory enhancing activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4098824A (en) *	1975-10-02	1978-07-04	Laboratoire L. Lafon	Benzhydrylsulphinyl derivatives
GB1584462A (en) *	1977-03-31	1981-02-11	Lafon Labor	N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
US6875893B2 (en) *	2002-05-23	2005-04-05	Cephalon, Inc.	Preparations of a sulfinyl acetamide
WO2004075841A2 (en) *	2003-02-24	2004-09-10	Mallinckrodt Inc.	Process for preparing benzhydrylthioacetamide

2004
- 2004-10-22 EP EP04796038A patent/EP1678129B1/de not_active Expired - Lifetime
- 2004-10-22 CA CA002543326A patent/CA2543326A1/en not_active Abandoned
- 2004-10-22 DK DK04796038T patent/DK1678129T3/da active
- 2004-10-22 AU AU2004285925A patent/AU2004285925A1/en not_active Abandoned
- 2004-10-22 MX MXPA06004403A patent/MXPA06004403A/es active IP Right Grant
- 2004-10-22 ES ES04796038T patent/ES2314464T3/es not_active Expired - Lifetime
- 2004-10-22 WO PCT/US2004/034975 patent/WO2005042479A1/en not_active Ceased
- 2004-10-22 DE DE602004017036T patent/DE602004017036D1/de not_active Expired - Fee Related
- 2004-10-22 US US10/570,243 patent/US7345188B2/en not_active Expired - Fee Related
- 2004-10-22 JP JP2006536808A patent/JP2007509161A/ja not_active Withdrawn
- 2004-10-22 SI SI200430988T patent/SI1678129T1/sl unknown
- 2004-10-22 PT PT04796038T patent/PT1678129E/pt unknown
- 2004-10-22 AT AT04796038T patent/ATE410410T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
SI1678129T1 (sl)	2009-10-31
US7345188B2 (en)	2008-03-18
PT1678129E (pt)	2008-11-26
US20080027240A1 (en)	2008-01-31
EP1678129A1 (de)	2006-07-12
DK1678129T3 (da)	2009-02-09
WO2005042479A1 (en)	2005-05-12
CA2543326A1 (en)	2005-05-12
JP2007509161A (ja)	2007-04-12
DE602004017036D1 (de)	2008-11-20
ES2314464T3 (es)	2009-03-16
AU2004285925A1 (en)	2005-05-12
MXPA06004403A (es)	2006-07-06
EP1678129B1 (de)	2008-10-08

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Legal Events

Date

Code

Title

Description

2009-05-15

UEP

Publication of translation of european patent specification

Ref document number: 1678129

Country of ref document: EP

2010-07-15

REN

Ceased due to non-payment of the annual fee