DK175196B1 - Transformeret filamentös fungusvært med en ekspressionskassette, DNA-konstruktion med en sådan ekspressionskassette og fremgangsmåde til fremstilling af et protein under anvendelse af en sådan transformert filamentös fungusvært - Google Patents
Transformeret filamentös fungusvært med en ekspressionskassette, DNA-konstruktion med en sådan ekspressionskassette og fremgangsmåde til fremstilling af et protein under anvendelse af en sådan transformert filamentös fungusvært Download PDFInfo
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- DK175196B1 DK175196B1 DK198903998A DK399889A DK175196B1 DK 175196 B1 DK175196 B1 DK 175196B1 DK 198903998 A DK198903998 A DK 198903998A DK 399889 A DK399889 A DK 399889A DK 175196 B1 DK175196 B1 DK 175196B1
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- 235000020183 skimmed milk Nutrition 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
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- 239000007787 solid Substances 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/905—Stable introduction of foreign DNA into chromosome using homologous recombination in yeast
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP88201743 | 1988-08-16 | ||
| EP88201743 | 1988-08-16 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK399889D0 DK399889D0 (da) | 1989-08-15 |
| DK399889A DK399889A (da) | 1990-02-17 |
| DK175196B1 true DK175196B1 (da) | 2004-07-05 |
Family
ID=8199839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK198903998A DK175196B1 (da) | 1988-08-16 | 1989-08-15 | Transformeret filamentös fungusvært med en ekspressionskassette, DNA-konstruktion med en sådan ekspressionskassette og fremgangsmåde til fremstilling af et protein under anvendelse af en sådan transformert filamentös fungusvært |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0357127B1 (fr) |
| JP (1) | JP2752714B2 (fr) |
| KR (1) | KR900003366A (fr) |
| AT (1) | ATE181111T1 (fr) |
| AU (1) | AU636572B2 (fr) |
| CA (1) | CA1341226C (fr) |
| DE (1) | DE68929013T2 (fr) |
| DK (1) | DK175196B1 (fr) |
| ES (1) | ES2134754T3 (fr) |
| FI (1) | FI110693B (fr) |
| GR (1) | GR3030901T3 (fr) |
| HU (1) | HUT51336A (fr) |
| IL (1) | IL91309A (fr) |
| PT (1) | PT91453B (fr) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69032616T2 (de) * | 1989-06-16 | 1999-03-11 | Genencor International, Inc., Rochester, N.Y. | Dna-sequenzen, vektoren und fusionspolypeptide zur erhöhung der sekretion gewünschter polypeptide von filamentösen fungi |
| NL9001388A (nl) | 1990-06-19 | 1992-01-16 | Unilever Nv | Recombinant dna, cel die daarvan afgeleid dna bevat, enzym waarvoor het recombinant dna codeert en toepassingen daarvan. |
| PT98419B (pt) * | 1990-07-24 | 1999-01-29 | Gist Brocades Nv | Processo para a preparacao de sequencias de adn que codificam para xilanases, de construcoes de adn que contem essas sequencias, paraa transformacao de hospedeiros microbianos com essas construcoes, para a preparacao de xilanases por expressao nesses hospedeiros e para a degradacao de xilano por accao dessas xilanases |
| AU664223B2 (en) * | 1991-12-09 | 1995-11-09 | Unilever Plc | Process for producing/secreting a protein by a transformed mould using expression/secretion regulating regions derived from an (aspergillus) endoxylanase II gene |
| AU4383293A (en) * | 1992-05-19 | 1993-12-13 | Tsi Corporation | Production of transgenics by joining regulatory and coding regions in vivo |
| WO1995017513A1 (fr) * | 1993-12-23 | 1995-06-29 | Novo Nordisk A/S | Retransformation de champignons filamenteux |
| BE1009488A4 (fr) * | 1994-06-17 | 1997-04-01 | Solvay | Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration. |
| BE1008737A3 (fr) * | 1994-01-28 | 1996-07-02 | Solvay | Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration. |
| BE1008267A3 (fr) * | 1994-01-28 | 1996-03-05 | Solvay | Systeme d'expression, vecteur d'integration et cellule transformee par ce vecteur d'integration. |
| JP5303084B2 (ja) | 1997-04-11 | 2013-10-02 | コニンクリーケ デーエスエム ナムローゼ フェンノートシャップ | 工業的組み換え生物を溝築するための手段としての遺伝子変換 |
| TW409035B (en) | 1997-06-04 | 2000-10-21 | Gist Brocades Bv | Starch-based enzyme granulates |
| EP3351637B1 (fr) | 2004-04-02 | 2020-06-10 | DSM IP Assets B.V. | Mutants fongiques filamenteux avec une efficacité améliorée de recombinaison homologue |
| EP1776461A2 (fr) | 2004-04-16 | 2007-04-25 | DSMIP Assets B.V. | Promoteurs fongiques destines a l'expression d'un gene dans une cellule fongique |
| CA2583460A1 (fr) | 2004-10-15 | 2006-04-20 | Dsm Ip Assets B.V. | Genes amds homologues utilises comme marqueur selectionnable |
| US7888489B2 (en) | 2005-01-24 | 2011-02-15 | Dsm Ip Assets B.V. | Method for producing a compound of interest in a filamentous fungal cell |
| CA2630445C (fr) | 2005-11-28 | 2016-11-15 | Dsm Ip Assets B.V. | Preparations d'enzymes au gout agreable |
| EP1954812B1 (fr) | 2005-11-29 | 2012-11-21 | DSM IP Assets B.V. | Site de liaison a l'adn d'un activateur transcriptionnel utile dans l'expression genetique |
| WO2007063133A2 (fr) | 2005-12-01 | 2007-06-07 | Dsm Ip Assets B.V. | Nouveaux gènes utiles pour la production industrielle d'acide citrique |
| EP2511372A1 (fr) | 2006-11-02 | 2012-10-17 | DSM IP Assets B.V. | Production améliorée de protéines sécrétées par des champignons filamenteux |
| EA018840B1 (ru) | 2007-02-15 | 2013-11-29 | ДСМ АйПи АССЕТС Б.В. | Рекомбинантная клетка-хозяин для получения соединения, представляющего интерес |
| JP5497632B2 (ja) | 2007-05-09 | 2014-05-21 | ノボザイムス アクティーゼルスカブ | 関心対象のポリペプチドを産生するライブラリークローンの選択に適した発現クローニング法 |
| EP2421986A1 (fr) | 2009-04-22 | 2012-02-29 | DSM IP Assets B.V. | Procédé de production d'un polypeptide recombinant d'intérêt |
| EA201201125A1 (ru) | 2010-02-11 | 2013-03-29 | ДСМ АйПи АССЕТС Б.В. | Клетка-хозяин, способная продуцировать ферменты, пригодные для деградации лигноцеллюлозного материала |
| AU2011273351A1 (en) | 2010-07-01 | 2013-01-17 | Dsm Ip Assets B.V. | A method for the production of a compound of interest |
| US20150197760A1 (en) | 2012-06-19 | 2015-07-16 | Dsm Ip Assets B.V. | Promoters for expressing a gene in a cell |
| WO2014003555A1 (fr) | 2012-06-27 | 2014-01-03 | Rijksuniversiteit Groningen | Production améliorée de pénicilline |
| JP6468561B2 (ja) | 2012-07-19 | 2019-02-13 | ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． | ＡｇｓＥ欠損株 |
| WO2014142647A1 (fr) | 2013-03-14 | 2014-09-18 | Wageningen Universiteit | Souches fongiques ayant une production améliorée d'acide citrique et d'acide itaconique |
| DK3077517T3 (en) | 2013-12-02 | 2019-02-11 | Dsm Ip Assets Bv | ISSTRUCTURING PROTEIN |
| EP3915384A1 (fr) | 2014-11-07 | 2021-12-01 | DuPont Nutrition Biosciences ApS | Cellule hôte recombinante exprimant bêta-galactosidase et/ou une activité de transgalactosylation déficient en cellulase |
| WO2016110512A1 (fr) | 2015-01-06 | 2016-07-14 | Dsm Ip Assets B.V. | Système crispr-cas pour une cellule hôte de levure |
| WO2016110453A1 (fr) | 2015-01-06 | 2016-07-14 | Dsm Ip Assets B.V. | Système crispr-cas pour cellule hôte fongique filamenteuse |
| US10590436B2 (en) | 2015-01-06 | 2020-03-17 | Dsm Ip Assets B.V. | CRISPR-CAS system for a lipolytic yeast host cell |
| WO2016193292A1 (fr) | 2015-06-02 | 2016-12-08 | Dsm Ip Assets B.V. | Utilisation de la protéine structurante de la glace afp19 exprimée dans des souches fongiques filamenteuses pour la préparation de produits alimentaires |
| US20200063166A1 (en) | 2017-03-13 | 2020-02-27 | Dsm Ip Assets B.V. | Zinc binuclear cluster transcriptional regulator-deficient strain |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK122686D0 (da) * | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| GB8610600D0 (en) * | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
| FI872102L (fi) * | 1986-06-06 | 1987-12-07 | Panlabs Inc | Expressionssystem hos filamentala fungi. |
| US4693536A (en) * | 1986-06-12 | 1987-09-15 | Molex Incorporated | Insulation displacement terminal |
| WO1989001969A1 (fr) * | 1987-09-04 | 1989-03-09 | Novo-Nordisk A/S | Procede de production de proteines dans aspergillus et promoteurs destines a exprimer ce champignon |
-
1989
- 1989-08-11 CA CA000608154A patent/CA1341226C/fr not_active Expired - Lifetime
- 1989-08-14 FI FI893818A patent/FI110693B/fi active IP Right Grant
- 1989-08-15 DK DK198903998A patent/DK175196B1/da not_active IP Right Cessation
- 1989-08-15 IL IL91309A patent/IL91309A/xx active IP Right Grant
- 1989-08-15 HU HU894197A patent/HUT51336A/hu unknown
- 1989-08-16 DE DE68929013T patent/DE68929013T2/de not_active Expired - Lifetime
- 1989-08-16 ES ES89202106T patent/ES2134754T3/es not_active Expired - Lifetime
- 1989-08-16 AU AU40021/89A patent/AU636572B2/en not_active Expired
- 1989-08-16 AT AT89202106T patent/ATE181111T1/de not_active IP Right Cessation
- 1989-08-16 JP JP1211210A patent/JP2752714B2/ja not_active Expired - Lifetime
- 1989-08-16 EP EP89202106A patent/EP0357127B1/fr not_active Expired - Lifetime
- 1989-08-16 PT PT91453A patent/PT91453B/pt not_active IP Right Cessation
- 1989-08-16 KR KR1019890011656A patent/KR900003366A/ko not_active Ceased
-
1999
- 1999-08-02 GR GR990401982T patent/GR3030901T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT91453B (pt) | 1995-05-31 |
| DE68929013T2 (de) | 1999-10-21 |
| JP2752714B2 (ja) | 1998-05-18 |
| ES2134754T3 (es) | 1999-10-16 |
| KR900003366A (ko) | 1990-03-26 |
| FI110693B (fi) | 2003-03-14 |
| IL91309A0 (en) | 1990-03-19 |
| GR3030901T3 (en) | 1999-11-30 |
| IL91309A (en) | 1997-11-20 |
| FI893818L (fi) | 1990-02-17 |
| AU4002189A (en) | 1990-02-22 |
| PT91453A (pt) | 1990-03-08 |
| CA1341226C (fr) | 2001-05-01 |
| DK399889A (da) | 1990-02-17 |
| JPH02174673A (ja) | 1990-07-06 |
| FI893818A0 (fi) | 1989-08-14 |
| HUT51336A (en) | 1990-04-28 |
| AU636572B2 (en) | 1993-05-06 |
| DK399889D0 (da) | 1989-08-15 |
| DE68929013D1 (de) | 1999-07-15 |
| EP0357127B1 (fr) | 1999-06-09 |
| ATE181111T1 (de) | 1999-06-15 |
| EP0357127A1 (fr) | 1990-03-07 |
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