DK1753512T3 - Tetrahydropyridothiophener - Google Patents

Tetrahydropyridothiophener

Info

Publication number
DK1753512T3
DK1753512T3 DK05749649T DK05749649T DK1753512T3 DK 1753512 T3 DK1753512 T3 DK 1753512T3 DK 05749649 T DK05749649 T DK 05749649T DK 05749649 T DK05749649 T DK 05749649T DK 1753512 T3 DK1753512 T3 DK 1753512T3
Authority
DK
Denmark
Prior art keywords
tetrahydropyridothiophenes
compounds
proliferative
description
meanings indicated
Prior art date
Application number
DK05749649T
Other languages
Danish (da)
English (en)
Inventor
Klaus Pekari
Thomas Baer
Bjoern Bartels
Mathias Schmidt
Thomas Beckers
Original Assignee
4Sc Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 4Sc Ag filed Critical 4Sc Ag
Application granted granted Critical
Publication of DK1753512T3 publication Critical patent/DK1753512T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK05749649T 2004-05-28 2005-05-25 Tetrahydropyridothiophener DK1753512T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP04102413 2004-05-28
EP04104193 2004-09-01
PCT/EP2005/052384 WO2005118071A2 (en) 2004-05-28 2005-05-25 Tetrahydropyridothiophenes

Publications (1)

Publication Number Publication Date
DK1753512T3 true DK1753512T3 (da) 2008-11-17

Family

ID=35045196

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05749649T DK1753512T3 (da) 2004-05-28 2005-05-25 Tetrahydropyridothiophener

Country Status (24)

Country Link
US (2) US7723523B2 (sr)
EP (1) EP1753512B1 (sr)
JP (1) JP4881297B2 (sr)
KR (1) KR20070037578A (sr)
CN (1) CN1988934B (sr)
AT (1) ATE400319T1 (sr)
AU (1) AU2005249718B2 (sr)
BR (1) BRPI0511461A (sr)
CA (1) CA2567648A1 (sr)
CY (1) CY1108399T1 (sr)
DE (1) DE602005008050D1 (sr)
DK (1) DK1753512T3 (sr)
EA (1) EA012280B1 (sr)
ES (1) ES2309765T3 (sr)
HR (1) HRP20080499T3 (sr)
IL (1) IL178727A (sr)
MX (1) MXPA06013383A (sr)
NO (1) NO20065907L (sr)
NZ (1) NZ550513A (sr)
PL (1) PL1753512T3 (sr)
PT (1) PT1753512E (sr)
RS (1) RS50613B (sr)
SI (1) SI1753512T1 (sr)
WO (1) WO2005118071A2 (sr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1753512T3 (da) 2004-05-28 2008-11-17 4Sc Ag Tetrahydropyridothiophener
CA2568718A1 (en) 2004-06-04 2005-12-15 Altana Pharma Ag Tetrahydropyridothiophenes for use in the treatment of cancer
CA2569623A1 (en) 2004-06-11 2005-12-22 Altana Pharma Ag Novel compounds and use of tetrahydropyridothiophenes
AU2006212224A1 (en) 2005-02-09 2006-08-17 4Sc Ag Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
CA2609003A1 (en) 2005-05-25 2006-11-30 Nycomed Gmbh Tetrahydropyridothiophenes for use in the treatment of cancer
EP1893618A2 (en) 2005-05-25 2008-03-05 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
WO2008020045A1 (en) * 2006-08-16 2008-02-21 4Sc Ag Tetrahydrobenzothiophene derivatives
JP2010500395A (ja) * 2006-08-16 2010-01-07 ４エスツェー アクチェンゲゼルシャフト 癌治療のためのテトラヒドロピリドチオフェン誘導体
TWI492759B (zh) * 2008-03-05 2015-07-21 Otsuka Pharma Co Ltd 膽甾烷醇衍生物之併用用途
TW201005466A (en) * 2008-07-24 2010-02-01 Advanced Analog Technology Inc Low dropout regulator
ES2392758T3 (es) * 2008-10-24 2012-12-13 Grünenthal GmbH 4,5,6,7-Tetrahidrotienopiridinas sustituidas como moduladores de KCNQ2/3 para el tratamiento del dolor, la epilepsia y la incontinencia urinaria
PT2404608E (pt) * 2009-03-04 2015-07-21 Otsuka Pharma Co Ltd Derivado de colestanol para utilização combinada
CN104478850A (zh) * 2014-12-08 2015-04-01 上海应用技术学院 一种2-氨基噻吩-3甲酰胺的衍生物的制备方法
AU2019291488B2 (en) 2018-06-19 2022-02-24 Novartis Ag N-substituted tetrahydrothienopyridine derivatives and uses thereof

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE272078C (sr)
DE1225167B (de) 1965-04-07 1966-09-22 Huels Chemische Werke Ag Verfahren zur Herstellung aliphatischer, aromatischer oder gemischt aliphatisch-aromatischer Sulfone
JPS5498337A (en) 1978-01-06 1979-08-03 Dai Ichi Seiyaku Co Ltd Anticarcinogenic and/or antimetastatic agent
DD272078A1 (de) 1986-04-15 1989-09-27 Dresden Arzneimittel Verfahren zur herstellung von 6-substituierten 2-acylamio-4,5,6,7-tetrahydro-thieno[2,3-c]-pyridin-3-carbonsaeure-derivaten
DE4039734A1 (de) 1990-12-13 1992-06-17 Basf Ag Substituierte 2-aminothiophene enthaltende herbizide mittel
GB9310700D0 (en) 1993-05-24 1993-07-07 Zeneca Ltd Novel composition
JP3074640B2 (ja) 1995-12-22 2000-08-07 インターナショナル・ビジネス・マシーンズ・コーポレ−ション 液晶表示装置の駆動方法
GB9614718D0 (en) * 1996-07-12 1996-09-04 Bayer Ag 3-ureido-pyridofurans and -pyridothiophenes
WO1999046267A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
CA2323493A1 (en) * 1998-03-12 1999-09-16 Todd Kevin Jones Modulators of protein tyrosine phosphatases (ptpases)
WO2000014090A1 (en) 1998-09-02 2000-03-16 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno[2,3-c]pyridine derivatives
GB0114185D0 (en) 2001-06-12 2001-08-01 Protherics Molecular Design Lt Compounds
WO2002092076A1 (en) 2001-05-16 2002-11-21 Cytovia, Inc. Substituted coumarins and quinolines as caspases activators
US20040171603A1 (en) 2001-05-18 2004-09-02 Janos Pato Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor
US20030232994A1 (en) 2001-10-04 2003-12-18 Shao-Po Lu Bicyclic thiophene derivatives and combinatorial libraries thereof
ES2300599T3 (es) 2002-03-27 2008-06-16 Nycomed Gmbh Derivados de alcoxipiridina.
JP4103425B2 (ja) 2002-03-28 2008-06-18 セイコーエプソン株式会社 電気光学装置、電子機器及び投射型表示装置
EP1492783A1 (en) 2002-04-09 2005-01-05 Axxima Pharmaceuticals AG 4,5,6,7-tretrahydrobenzo(b) thiophene derivatives and methods for medical intervention against mycrobacterial infections
US7012100B1 (en) 2002-06-04 2006-03-14 Avolix Pharmaceuticals, Inc. Cell migration inhibiting compositions and methods and compositions for treating cancer
CA2498106A1 (en) 2002-09-12 2004-03-25 Merck & Co., Inc. Substituted bicyclic thiophene derivatives, compositions containing such compounds and methods of use
CA2498399A1 (en) 2002-09-12 2004-03-25 Merck & Co., Inc. Method of treating diabetes and related conditions
TW200503994A (en) 2003-01-24 2005-02-01 Novartis Ag Organic compounds
IL154306A0 (en) 2003-02-05 2003-09-17 Rimonyx Pharmaceuticals Ltd Pharmaceutical compositions comprising thieno [2,3-c] pyridine derivatives and use thereof
US7138529B2 (en) 2003-04-16 2006-11-21 Hoffmann-La Roche Inc. Substituted 3-cyanothiophene acetamides as glucagon receptor antagonists
WO2005023818A2 (en) 2003-09-10 2005-03-17 Gpc Biotech Ag Heterobicyclic compounds as pharmaceutically active agents
ES2308260T3 (es) 2003-10-01 2008-12-01 Nycomed Gmbh Derivados de imidazopiridinas como inhibidores de no-sintasa inducible.
US20050085531A1 (en) 2003-10-03 2005-04-21 Hodge Carl N. Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
GB0324653D0 (en) 2003-10-22 2003-11-26 Syngenta Participations Ag Fungicides
JP2007515429A (ja) 2003-12-19 2007-06-14 エリクシアー ファーマシューティカルズ， インコーポレイテッド 障害を治療する方法
US7745630B2 (en) 2003-12-22 2010-06-29 Justin Stephen Bryans Triazolyl piperidine arginine vasopressin receptor modulators
DK1753512T3 (da) 2004-05-28 2008-11-17 4Sc Ag Tetrahydropyridothiophener
CA2568718A1 (en) 2004-06-04 2005-12-15 Altana Pharma Ag Tetrahydropyridothiophenes for use in the treatment of cancer
CA2569623A1 (en) 2004-06-11 2005-12-22 Altana Pharma Ag Novel compounds and use of tetrahydropyridothiophenes
SE0401970D0 (sv) 2004-08-02 2004-08-02 Astrazeneca Ab Novel compounds
AU2006212224A1 (en) 2005-02-09 2006-08-17 4Sc Ag Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
AU2006212179A1 (en) 2005-02-11 2006-08-17 4Sc Ag Tetrahydropyridothiophenes as antripoliferative agents for the treatment of cancer
CA2609003A1 (en) 2005-05-25 2006-11-30 Nycomed Gmbh Tetrahydropyridothiophenes for use in the treatment of cancer
EP1893618A2 (en) 2005-05-25 2008-03-05 Nycomed GmbH Tetrahydropyridothiophenes for use in the treatment of cancer
WO2008020045A1 (en) 2006-08-16 2008-02-21 4Sc Ag Tetrahydrobenzothiophene derivatives

Also Published As

Publication number Publication date
PT1753512E (pt) 2008-10-14
JP4881297B2 (ja) 2012-02-22
DE602005008050D1 (de) 2008-08-21
RS50613B (sr) 2010-06-30
MXPA06013383A (es) 2007-01-23
ATE400319T1 (de) 2008-07-15
EA200602157A1 (ru) 2007-06-29
HRP20080499T3 (en) 2008-11-30
SI1753512T1 (sl) 2008-12-31
EP1753512A2 (en) 2007-02-21
WO2005118071A3 (en) 2006-06-01
US20090270378A1 (en) 2009-10-29
EA012280B1 (ru) 2009-08-28
CA2567648A1 (en) 2005-12-15
HK1106171A1 (en) 2008-03-07
CN1988934B (zh) 2011-01-05
ES2309765T3 (es) 2008-12-16
EP1753512B1 (en) 2008-07-09
NZ550513A (en) 2009-10-30
AU2005249718B2 (en) 2011-01-27
AU2005249718A1 (en) 2005-12-15
KR20070037578A (ko) 2007-04-05
JP2008500993A (ja) 2008-01-17
US20070244112A1 (en) 2007-10-18
CN1988934A (zh) 2007-06-27
PL1753512T3 (pl) 2009-03-31
IL178727A0 (en) 2007-02-11
US7723523B2 (en) 2010-05-25
BRPI0511461A (pt) 2007-12-26
IL178727A (en) 2010-12-30
CY1108399T1 (el) 2014-02-12
US7803945B2 (en) 2010-09-28
WO2005118071A2 (en) 2005-12-15
NO20065907L (no) 2006-12-19

Similar Documents

Publication Publication Date Title
CY1108399T1 (el) Τετραϋδροπυριδοθειοφαινια
NL301145I2 (nl) Tirbanibulin
CY1122522T1 (el) Μετα αρσενικωδες νατριο για χρηση στην αγωγη του πολλαπλου μυελωματος
ATE517896T1 (de) P38-kinase-inhibitoren
UA96592C2 (uk) Індолопіридини як модулятори кінезину eg5
EA200900781A1 (ru) 4-фенилпиран-3,5-дионы, 4-фенилтиопиран-3,5-дионы и циклогексантрионы, как новые гербициды
ATE461217T1 (de) Glp-1-verbindungen
DE602005002413D1 (de) Wegwerfhöschen
DK1585737T3 (da) Uraciler med herbicid virkning
EA200700717A1 (ru) Сульфонамиды
WO2008006883A3 (en) Benzopyranopyrazoles
ATE486878T1 (de) Benzothienopyridine zur verwendung als inhibitoren von eg5-kinesin
WO2005118592A8 (en) Tetrahydropyridothiophenes for use in the treatment of cancer
WO2006125815A3 (en) Tetrahydropyridothiophenes for use in the treatment of cancer
WO2006125813A3 (en) Tetrahydropyridothiophenes for use in the treatment of cancer
FR2858695B1 (fr) Calculateur personnel.
ES1058102Y (es) Lentilla terapeutica.
NL1026117A1 (nl) Rolstoel.
UY34598A (es) Antranilamidas insecticidas
ES1058437Y (es) Mesa.
ES1057785Y (es) Muñequera portaobjetos.
ES1057650Y (es) Camison hospitalario.
UA5977U (en) 5-phenylpropenelydene-rodanin-3-propionate sodium possesses antihypoxic activity
ES1051639Y (es) Mesa de juegos.
ES1052699Y (es) Piragua desmontable.