DK1766412T3 - Sammensætninger og fremgangsmåder til kvantificering af serumglycoproteiner - Google Patents

Sammensætninger og fremgangsmåder til kvantificering af serumglycoproteiner

Info

Publication number
DK1766412T3
DK1766412T3 DK05751819T DK05751819T DK1766412T3 DK 1766412 T3 DK1766412 T3 DK 1766412T3 DK 05751819 T DK05751819 T DK 05751819T DK 05751819 T DK05751819 T DK 05751819T DK 1766412 T3 DK1766412 T3 DK 1766412T3
Authority
DK
Denmark
Prior art keywords
compositions
methods
serum glycoproteins
quantifying serum
quantifying
Prior art date
Application number
DK05751819T
Other languages
Danish (da)
English (en)
Inventor
Rudolph H Aebersold
Hui Zhang
Original Assignee
Inst Systems Biology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Systems Biology filed Critical Inst Systems Biology
Application granted granted Critical
Publication of DK1766412T3 publication Critical patent/DK1766412T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material
    • G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
DK05751819T 2004-05-21 2005-05-20 Sammensætninger og fremgangsmåder til kvantificering af serumglycoproteiner DK1766412T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57359304P 2004-05-21 2004-05-21
PCT/US2005/017842 WO2005114221A2 (fr) 2004-05-21 2005-05-20 Compositions et methodes de quantification de glycoproteines du serum

Publications (1)

Publication Number Publication Date
DK1766412T3 true DK1766412T3 (da) 2009-05-25

Family

ID=35429005

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05751819T DK1766412T3 (da) 2004-05-21 2005-05-20 Sammensætninger og fremgangsmåder til kvantificering af serumglycoproteiner

Country Status (6)

Country Link
US (2) US20060141528A1 (fr)
EP (4) EP1766412B1 (fr)
AT (1) ATE427499T1 (fr)
DE (1) DE602005013670D1 (fr)
DK (1) DK1766412T3 (fr)
WO (1) WO2005114221A2 (fr)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE344456T1 (de) * 2000-05-05 2006-11-15 Purdue Research Foundation Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen
EP1432992A2 (fr) * 2001-09-27 2004-06-30 Purdue Research Foundation Materiaux et procedes regulant les effets isotopiques lors du fractionnement d'analytes
DE10254601A1 (de) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
US7384754B2 (en) * 2003-10-31 2008-06-10 Agilent Technologies, Inc. Enrichment and tagging of glycosylated proteins
DE102004024617A1 (de) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
US20070099251A1 (en) * 2005-10-17 2007-05-03 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
EP1790664A1 (fr) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Anticorps monoclonaux contre claudin-18 pour le traitement du cancer
JP5244103B2 (ja) 2006-08-09 2013-07-24 ホームステッド クリニカル コーポレイション 器官特異的蛋白質およびその使用方法
US7879799B2 (en) * 2006-08-10 2011-02-01 Institute For Systems Biology Methods for characterizing glycoproteins and generating antibodies for same
DK2155228T3 (da) 2007-01-10 2014-07-07 Purdue Research Foundation Polypeptidinhibitorer af HSP27-kinase og anvendelser herfor
US20100184049A1 (en) * 2007-04-27 2010-07-22 Steve Goodison Glycoprotein Profiling of Bladder Cancer
US8603734B2 (en) * 2007-06-04 2013-12-10 The Johns Hopkins University Biomarkers for prostate cancer
US20100168382A1 (en) * 2007-06-12 2010-07-01 Vladimir Berezin Neuroplastin derived peptides
JP2010530962A (ja) * 2007-06-12 2010-09-16 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 血漿においてタンパク質を検出する方法
EP2174134B1 (fr) * 2007-07-03 2013-10-09 NorthEastern University Biomarqueurs pour le diabete, l'obesite, et/ou l'hypertension
US20100204128A1 (en) * 2007-07-24 2010-08-12 Sanare Investment As Novel peptides
JP5703466B2 (ja) 2007-08-07 2015-04-22 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ キナーゼ阻害薬およびその使用
AU2009208607B2 (en) * 2008-01-31 2013-08-01 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
AU2009324661A1 (en) 2008-12-10 2011-07-07 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
EP2427844A4 (fr) 2009-05-08 2016-11-02 Thermo Finnigan Llc Procédés et systèmes de mise en correspondre de productions et d'ions de précurseur
WO2011007764A1 (fr) * 2009-07-14 2011-01-20 独立行政法人産業技術総合研究所 Marqueur de chaîne de sucre comme mesure d'états de maladie de maladies hépatiques
WO2011017132A2 (fr) 2009-07-27 2011-02-10 Purdue Research, Foundation Compositions d'inhibiteurs de mk2 et procédés d'amélioration de l'excroissance des neurites, de la neuroprotection et de la régénération des nerfs
WO2011143386A1 (fr) * 2010-05-14 2011-11-17 Dh Technologies Development Pte. Ltd. Systèmes et procédés de calcul de degrés de certitude de protéines
US8969524B2 (en) * 2010-10-27 2015-03-03 Baxter International Inc. FVIII peptides for immune tolerance induction and immunodiagnostics
US9403889B2 (en) 2010-11-29 2016-08-02 Integrated Diagnostics, Inc. Diagnostic lung cancer panel and methods for its use
US8772043B2 (en) 2010-12-23 2014-07-08 Pioneer Hi Bred International Inc Universal peptide tags for transgene polypeptide analysis by mass spectrometry
JP6047150B2 (ja) * 2011-05-13 2016-12-21 キングス・カレッジ・ロンドン 血小板感受性に関係する方法と組成物
US8455624B2 (en) 2011-06-03 2013-06-04 University Of South Alabama Methods and compositions for detecting endometrial or ovarian cancer
US9506167B2 (en) 2011-07-29 2016-11-29 Ginkgo Bioworks, Inc. Methods and systems for cell state quantification
CA2848162C (fr) 2011-09-12 2023-03-14 Creatics Llc Procedes non invasifs de detection de molecules cibles
CN103134874B (zh) * 2011-12-01 2015-05-20 成都康弘生物科技有限公司 一种测定蛋白中糖基的方法
US9304137B2 (en) 2011-12-21 2016-04-05 Integrated Diagnostics, Inc. Compositions, methods and kits for diagnosis of lung cancer
US11913957B2 (en) 2011-12-21 2024-02-27 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
AU2012358246B2 (en) 2011-12-21 2018-01-25 Integrated Diagnostics, Inc. Methods for diagnosis of lung cancer
JP6416627B2 (ja) * 2012-01-09 2018-10-31 セルピン ファーマ リミテッド ライアビリティ カンパニー ペプチドおよびその使用法
WO2013134636A1 (fr) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions et procédés d'administration de peptides inhibiteurs de kinases
WO2013167153A1 (fr) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Anticorps utiles dans le diagnostic du cancer
EP2918600B1 (fr) * 2012-11-06 2019-04-24 University of Miyazaki Nouveau peptide et son utilisation
WO2014100717A2 (fr) 2012-12-21 2014-06-26 Integrated Diagnostics, Inc. Compositions, procédés et kits pour le diagnostic d'un cancer du poumon
CA2902841A1 (fr) 2013-03-13 2014-10-02 Creatics Llc Procedes et compositions pour detecter un cancer du pancreas
GB201310150D0 (en) * 2013-06-07 2013-07-24 Electrophoretics Ltd Methods and compositions relating to alzheimer's disease
CN105793710B (zh) 2013-07-26 2019-04-09 佰欧迪塞克斯公司 用于肺癌诊断的组合物、方法和试剂盒
US9594085B2 (en) 2014-02-03 2017-03-14 Integrated Diagnostics, Inc. Integrated quantification method for protein measurements in clinical proteomics
HRP20200967T1 (hr) 2014-06-20 2020-10-16 Immatics Biotechnologies Gmbh Nova imunoterapija protiv nekoliko tumora krvi, posebice kronične limfoidne leukemije (cll)
GB201411037D0 (en) * 2014-06-20 2014-08-06 Immatics Biotechnologies Gmbh Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL)
WO2016038608A1 (fr) * 2014-09-08 2016-03-17 Carmel Haifa University Economic Corporation Ltd. Peptides dérivés du récepteur de l'angiotensine et leur utilisation
WO2016054114A1 (fr) 2014-09-29 2016-04-07 The Regents Of The University Of California Composition pour l'expansion de lymphocytes t régulateurs (treg), et le traitement de maladies et affections auto-immunes et inflammatoires
GB201505305D0 (en) 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
FI3273986T3 (fi) 2015-03-27 2024-02-07 Immatics Biotechnologies Gmbh Uusia peptidejä ja peptidien yhdistelmiä käytettäväksi immunoterapiassa eri syöpiä vastaan
CN113429455B (zh) 2015-08-28 2024-11-22 赛品制药有限责任公司 用于疾病治疗的方法
GB201520550D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201520559D0 (en) * 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201520568D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd Peptides
US10802027B2 (en) 2016-05-05 2020-10-13 Biodesix, Inc. Compositions, methods and kits for diagnosis of lung cancer
US9960027B2 (en) 2016-05-25 2018-05-01 Thermo Finnigan Llc Analyzing a complex sample by MS/MS using isotopically-labeled standards
AU2018324195B2 (en) * 2017-09-01 2024-12-12 Venn Biosciences Corporation Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring
ES2710321A1 (es) * 2017-10-20 2019-04-24 Consejo Superior Investigacion Adn polimerasas independientes de cebador y su uso para la sintesis de adn
WO2020223646A1 (fr) 2019-05-02 2020-11-05 Creatics Llc Méthodes de détection du cancer par évaluation de alpha-1-antitrypsine (aat) et elastase de type chymotrypsine dans des échantillons de fluide de lavage gastro-intestinal
CN110563844A (zh) * 2019-09-04 2019-12-13 华中农业大学 一种抗犬白介素31受体的多克隆抗体及其应用
WO2021050510A1 (fr) * 2019-09-09 2021-03-18 The Wistar Institute Of Anatomy And Biology Compositions de peptides modifiés et de mimétiques peptidiques et méthodes
ES2984813T3 (es) * 2020-04-28 2024-10-31 Janssen Pharmaceuticals Inc Método para la identificación y la cuantificación de polisacáridos en composiciones de glicoconjugados complejas
US12105093B2 (en) 2020-07-28 2024-10-01 University Of Washington Quantitation of GLA proteins by mass spectrometric analysis
EP4053559A1 (fr) * 2021-03-01 2022-09-07 Consorcio Centro de Investigación Biomédica en Red, M.P. (CIBER) Procédés de mesure de la protéine c et de la protéine c activée
US20240219400A1 (en) * 2021-04-29 2024-07-04 Seer, Inc. Peptide decorated nanoparticles for enrichment of specific protein subsets
CN113480629B (zh) * 2021-06-16 2022-08-19 复旦大学 区分肝癌和正常人的末端唾液酸化异构糖肽标志物及其筛查方法
CN115490763A (zh) * 2021-06-18 2022-12-20 佛山热休生物技术有限公司 Lum的表位肽及所述表位肽与热休克蛋白的复合物
US11542340B1 (en) 2021-10-29 2023-01-03 Biodesix, Inc. Antibodies targeting pulmonary nodule specific biomarkers and uses thereof
NL2030990B1 (en) * 2022-02-17 2023-09-01 Academisch Ziekenhuis Leiden T cell receptors directed against jchain and uses thereof
WO2023164697A2 (fr) * 2022-02-28 2023-08-31 PrognomIQ, Inc. Évaluation de glycoprotéine
JP2025535396A (ja) * 2022-10-21 2025-10-24 クアンタム－エスアイ インコーポレイテッド ポリペプチジルリンカー
CN117969642B (zh) * 2024-04-02 2024-07-23 浙江大学 一种植物n-糖链的精准相对定量分析方法及应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2226032B (en) * 1988-12-16 1993-08-18 Urs Heimgartner Detection of glycoproteins
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5079336A (en) * 1989-06-23 1992-01-07 The Trustees Of The University Of Pennsylvania α-1-antichymotrypsin, analogues and methods of production
US5264563A (en) 1990-08-24 1993-11-23 Ixsys Inc. Process for synthesizing oligonucleotides with random codons
GB9112504D0 (en) * 1991-06-11 1991-07-31 Merck Sharp & Dohme Cell line
US5986076A (en) 1994-05-11 1999-11-16 Trustees Of Boston University Photocleavable agents and conjugates for the detection and isolation of biomolecules
JPH10507160A (ja) 1994-06-23 1998-07-14 アフィマックス テクノロジーズ エヌ．ブイ． 光活性化合物およびその使用方法
JP4503706B2 (ja) * 1996-06-07 2010-07-14 ポニアード ファーマシューティカルズ，インコーポレイティド グリコシル化が改質されたヒト化抗体
EP0959893A4 (fr) * 1996-12-10 2004-11-10 Sloan Kettering Institutefor C Procede et compositions destines a stimuler une reponse immune a l'egard d'un antigene de differenciation stimule par un antigene modifie
US6046013A (en) * 1997-08-01 2000-04-04 Gti Process for identifying specific antibodies associated with HLA
EP1329513B1 (fr) 1998-08-25 2011-12-07 University of Washington Analyse quantitative rapide de protéines ou de fonction protéique dans des mélanges complexes
US6407210B1 (en) * 1998-11-09 2002-06-18 University Of Utah Research Foundation Nematode neuromuscular junction GABA receptors and methods related thereto
JP2003518364A (ja) * 1999-05-28 2003-06-10 ルードヴィッヒ インスティテュート フォー キャンサー リサーチ 乳癌、胃癌および前立腺癌関連抗原ならびにそれらの使用
WO2002052259A1 (fr) 2000-12-26 2002-07-04 The Institute For Systems Biology Analyse rapide et quantitative des proteomes et procedes associes
CA2444882A1 (fr) * 2001-04-30 2002-11-07 Vertex Pharmaceuticals Incorporated Inhibiteurs de gsk-3 et structures cristallines de la proteine gsk-3.beta. et de complexes proteiques
EP1432992A2 (fr) * 2001-09-27 2004-06-30 Purdue Research Foundation Materiaux et procedes regulant les effets isotopiques lors du fractionnement d'analytes
WO2003102018A2 (fr) * 2002-06-03 2003-12-11 The Institute For Systems Biology Procedes d'analyse proteomique quantitative de glycoproteines
WO2005007677A2 (fr) * 2003-07-10 2005-01-27 The Institute For Systems Biology Capture par affinite de peptides par micro-agencement et methodes associees
US7593336B2 (en) * 2003-10-31 2009-09-22 Brocade Communications Systems, Inc. Logical ports in trunking
US7348416B2 (en) * 2003-11-21 2008-03-25 Applera Corporation Selective capture and enrichment of proteins expressed on the cell surface

Also Published As

Publication number Publication date
EP2302394A1 (fr) 2011-03-30
EP1766412A2 (fr) 2007-03-28
ATE427499T1 (de) 2009-04-15
EP1766412B1 (fr) 2009-04-01
EP2093569A3 (fr) 2009-11-11
DE602005013670D1 (de) 2009-05-14
WO2005114221A2 (fr) 2005-12-01
EP2302393A1 (fr) 2011-03-30
WO2005114221A8 (fr) 2006-05-04
EP2093569A2 (fr) 2009-08-26
EP2302393A8 (fr) 2011-08-03
WO2005114221A3 (fr) 2006-12-21
US20060141528A1 (en) 2006-06-29
US20100279382A1 (en) 2010-11-04

Similar Documents

Publication Publication Date Title
ATE427499T1 (de) Zusammensetzungen und verfahren zur quantifizierung von serumglykoproteinen
DK1510492T3 (da) Fremgangsmåde til afprövning af et elevatoranlæg og elevatoranlæg
WO2005111212A3 (fr) Code-barres biologique
WO2005012574A3 (fr) Code a barres biologique
WO2007007192A8 (fr) Utilisation de matrices ioniques pour l'analyse par la spectrometrie de desorption-ionisation par impact laser assistee par matrice
DK1740197T3 (da) Prolyl-endopeptidease (PEP) og glutamin-endoprotease til behandlingen af cøliaki
NO20035010D0 (no) Fremgangsmåter og blandinger for analysering av proteiner
DK1680443T3 (da) Stabiliserede alfa-helix-peptider og anvendelser heraf
DK1293574T3 (da) Reagenser, fremgangsmåder og indretninger til bestemmelse af analytter
DE60335733D1 (de) Verfahren zur solubilisierung von protein
FR14C0007I2 (fr) Remodelage et glycoconjugaison de peptides
DE60309492D1 (de) Arbeitsplatz zur bereitstellung proben
DE60217696D1 (de) Vorrichtung zur wirbelsäulenfixierung
DK1454992T3 (da) Anaplastisk lymfomakinaseassay, reagenser og sammensætninger deraf
DE50204020D1 (de) Mikrotom
DK1368689T3 (da) Fremgangsmåde til estimering af den bedste indledende fokusposition
ATE446314T1 (de) Methode zur reinigung von fsh
DE60213941D1 (de) Proben-Einführungssystem
DK2327792T3 (da) Fremgangsmåder og sammensætninger til påvisning af autoimmunsygdomme
ATE363070T1 (de) Auswertung von biologischen mitteln in lebenden zielzellen
MXPA04004018A (es) Metodos de separacion por exclusion para toxicidad de compuestos de prueba.
DK1406684T3 (da) Fremgangsmåde til at forøge pålideligheden af sporbarheden af blodprøver
WO2007095378A3 (fr) Marquage de masse pour l'analyse quantitative de biomolécules au moyen de phénylisocyanate étiqueté 13c
DE50200752D1 (de) Mikrotom
DE50115247D1 (de) Sensor zur zustandsbestimmung von kenngrössen an mechanischen komponenten unter verwendung von amorpschaften