DK185485A - Trans-(+) (-)-octahydrothiazolo/4,5-g/quinoliner og enantiomere deraf samt fremgangsmaade til fremstilling af saadanne forbindelser - Google Patents

Trans-(+) (-)-octahydrothiazolo/4,5-g/quinoliner og enantiomere deraf samt fremgangsmaade til fremstilling af saadanne forbindelser Download PDF

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Publication number
DK185485A
DK185485A DK185485A DK185485A DK185485A DK 185485 A DK185485 A DK 185485A DK 185485 A DK185485 A DK 185485A DK 185485 A DK185485 A DK 185485A DK 185485 A DK185485 A DK 185485A
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DK
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Prior art keywords
sub
enantiomers
octahydrothiazolo
quinolines
trans
Prior art date
Application number
DK185485A
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Danish (da)
English (en)
Other versions
DK185485D0 (da
Inventor
Robert Daniel Titus
Edmund Carl Kornfeld
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK185485D0 publication Critical patent/DK185485D0/da
Publication of DK185485A publication Critical patent/DK185485A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C07D215/30—Metal salts; Chelates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK185485A 1984-04-27 1985-04-25 Trans-(+) (-)-octahydrothiazolo/4,5-g/quinoliner og enantiomere deraf samt fremgangsmaade til fremstilling af saadanne forbindelser DK185485A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/604,687 US4537893A (en) 1984-04-27 1984-04-27 Octahydrothiazolo[4,5-g]quinolines and use as prolactin secretion inhibitors
US60468784 1984-04-27

Publications (2)

Publication Number Publication Date
DK185485D0 DK185485D0 (da) 1985-04-25
DK185485A true DK185485A (da) 1985-10-28

Family

ID=24420601

Family Applications (1)

Application Number Title Priority Date Filing Date
DK185485A DK185485A (da) 1984-04-27 1985-04-25 Trans-(+) (-)-octahydrothiazolo/4,5-g/quinoliner og enantiomere deraf samt fremgangsmaade til fremstilling af saadanne forbindelser

Country Status (19)

Country Link
US (1) US4537893A (de)
EP (1) EP0160502B1 (de)
JP (1) JPH0631262B2 (de)
KR (1) KR870001072B1 (de)
CN (1) CN85101547A (de)
AT (1) ATE67767T1 (de)
AU (1) AU564946B2 (de)
CA (1) CA1287356C (de)
DE (1) DE3584183D1 (de)
DK (1) DK185485A (de)
ES (1) ES8704177A1 (de)
GR (1) GR850989B (de)
HU (1) HU193113B (de)
IL (1) IL74988A0 (de)
NZ (1) NZ211863A (de)
PH (1) PH21951A (de)
PT (1) PT80339B (de)
SU (1) SU1414318A3 (de)
ZA (1) ZA852999B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4778894A (en) * 1983-09-26 1988-10-18 Eli Lilly And Company 6 oxo-decahydroquinolines
US4977160A (en) * 1986-06-16 1990-12-11 Eli Lilly And Company BCD tricyclic ergoline part-structure analogues
US5134143A (en) * 1986-06-16 1992-07-28 Eli Lilly And Company BCD tricyclic ergoline part-structure analogues
US4826986A (en) * 1986-06-16 1989-05-02 Eli Lilly And Company 6-Oxo-trans-octa- and decahydroquinolines
DE3624607A1 (de) * 1986-07-21 1988-01-28 Boehringer Ingelheim Kg Neue tetrahydrobenzothiazolo-chinoline ihre herstellung und verwendung
US4762843A (en) * 1986-09-15 1988-08-09 Warner-Lambert Company Hetero [f] fused carbocyclic pyridines as dopaminergic agents
US4939259A (en) * 1989-07-24 1990-07-03 Eli Lilly And Company 2-oxo-pyrido[2,3-g]quinoline derivatives
US5006525A (en) * 1989-07-24 1991-04-09 Eli Lilly And Company Dopamine agonists method
US4977149A (en) * 1989-07-24 1990-12-11 Eli Lilly And Company Pyridoquinoline dopamine agonists, compositions and use
US5057515A (en) * 1989-07-24 1991-10-15 Eli Lilly And Company Method for agonizing a dopamine receptor
US5416090A (en) * 1991-01-31 1995-05-16 Eli Lilly And Company Method of treating inflammation
CA2144669A1 (en) * 1994-03-29 1995-09-30 Kozo Akasaka Biphenyl derivatives
EP0816406B1 (de) * 1996-06-26 2000-09-06 Bayer Ag Verfahren zur Herstellung salzarmer Präparationen von Kondensationsprodukten
WO2009139855A2 (en) * 2008-05-14 2009-11-19 Ipsen Pharma S.A.S. Pharmaceutical compositions of somatostatin-dopamine conjugates
TWI537274B (zh) * 2011-03-14 2016-06-11 橘生藥品工業股份有限公司 新穎之八氫噻吩并喹啉衍生物、含有其之醫藥組成物及該等之用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2056224A1 (de) * 1969-11-17 1971-06-03 Danchi Seiyaku Co , Ltd , Tokio Neue Thiazolochinohnderivate und Ver fahren zu ihrer Herstellung
US4198415A (en) * 1979-01-22 1980-04-15 Eli Lilly And Company Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines
US4258049A (en) * 1979-07-02 1981-03-24 Smithkline Corporation Inhibiting phenylethanolamine N-methyltransferase with thiadiazolo and oxadiazolotetrahydroisoquinolines
US4367231A (en) * 1979-09-14 1983-01-04 Eli Lilly And Company Method of using octahydro pyrazolo[3,4-g]quinolines

Also Published As

Publication number Publication date
EP0160502A2 (de) 1985-11-06
HU193113B (en) 1987-08-28
DK185485D0 (da) 1985-04-25
CA1287356C (en) 1991-08-06
JPH0631262B2 (ja) 1994-04-27
PT80339A (en) 1985-05-01
EP0160502B1 (de) 1991-09-25
ZA852999B (en) 1986-11-26
AU4166685A (en) 1985-10-31
CN85101547A (zh) 1987-01-24
JPS60233091A (ja) 1985-11-19
PH21951A (en) 1988-04-15
ES542565A0 (es) 1987-03-16
NZ211863A (en) 1987-10-30
IL74988A0 (en) 1985-08-30
HUT37624A (en) 1986-01-23
GR850989B (de) 1985-11-25
SU1414318A3 (ru) 1988-07-30
ES8704177A1 (es) 1987-03-16
PT80339B (en) 1987-02-16
AU564946B2 (en) 1987-09-03
EP0160502A3 (en) 1987-03-11
DE3584183D1 (de) 1991-10-31
KR870001072B1 (ko) 1987-05-27
KR850007261A (ko) 1985-12-02
ATE67767T1 (de) 1991-10-15
US4537893A (en) 1985-08-27

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