DK2479266T3 - Amylaser og glucoamylaser, nukleinsyrer, som koder for dem, og fremgangsmåder til fremstilling og anvendelse deraf - Google Patents

Amylaser og glucoamylaser, nukleinsyrer, som koder for dem, og fremgangsmåder til fremstilling og anvendelse deraf Download PDF

Info

Publication number
DK2479266T3
DK2479266T3 DK12152656.0T DK12152656T DK2479266T3 DK 2479266 T3 DK2479266 T3 DK 2479266T3 DK 12152656 T DK12152656 T DK 12152656T DK 2479266 T3 DK2479266 T3 DK 2479266T3
Authority
DK
Denmark
Prior art keywords
polypeptide
nucleic acid
composition
sequence
starch
Prior art date
Application number
DK12152656.0T
Other languages
English (en)
Inventor
Malgorzata Slupska
Yan Zhang
Geoff Hazlewood
Cathy Chang
Peter Luginbuhl
Ellen Burke
Michelle Cayouette
Uvini Gunavardena
Majid Ghassemian
Aron Silverstone
Original Assignee
Basf Enzymes Llc
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39563240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2479266(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Basf Enzymes Llc, Syngenta Participations Ag filed Critical Basf Enzymes Llc
Application granted granted Critical
Publication of DK2479266T3 publication Critical patent/DK2479266T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2425—Beta-amylase (3.2.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Liquid Carbonaceous Fuels (AREA)

Claims (26)

1. Isoleret, syntetisk eller rekombinant nukleinsyre bestående af: (a) en nukleinsyresekvens, der er mindst 98%, 99% eller 100% identisk med SEQ ID NO:51, hvor nukleinsyren koder for mindst et polypeptid med en alpha-amylase-aktivitet; (b) en nukleinsyresekvens, der koder for et polypeptid med sekvensen i SEQ ID NO:52; (c) en nukleinsyresekvens, der er fuldstændig komplementær til (a) eller (b); eller (d) en nukleinsyresekvens som angivet i SEQ ID NO:51.
2. Isoleret, syntetisk eller rekombinant nukleinsyresekvens som angivet i SEQ ID NO:51, hvor nukleinsyren koder for et polypeptid med en alpha-amylase-aktivitet og en aminosyresekvens som angivet i SEQ ID NO:52.
3. Vektor, ekspressionskassette eller kloningsvehikel omfattende en nukleinsyre, der omfatter nukleinsyresekvensen ifølge krav 1; hvor nukleinsyren eventuelt er funktionsmæssigt forbundet med en promoter; hvor promoteren eventuelt er en plantepromotor eller en viral promotor; hvor hvor promotoren eventuelt er en inducerbar promotor eller en vævsspecifik promotor; hvor den vævsspecifikke promotor eventuelt er frø-specifik, en endosperm-specifik promoter, en blad-specifik, en rod-specifik, en stam-specifik eller en afskærings-induceret promoter.
4. Transformeret celle, omfattende en nukleinsyre omfattende nukleinsyresekvensen ifølge krav 1, eller en vektor, ekspressionskassette eller kloningsvehikel ifølge krav 3, hvor cellen eventuelt er en bakteriecelle, en pattedyrscelle, en svampecelle, en gærcelle, en insektcelle eller en plantecelle, hvor plantecellen eventuelt er en kartoffel-, ris-, majs-, hvede-, tobaks- eller bygcelle.
5. Isoleret, syntetisk eller rekombinant polypeptid med alpha-amylase-aktivitet, omfattende: (i) en aminosyresekvens, der er mindst 99 % eller fuldstændig identisk med sekvensen med SEQ ID NO:52 over den fulde længde af polypeptidet; (ii) en aminosyresekvens, der kodes af nukleinsyren ifølge krav 1; (iii) polypeptidet ifølge et hvilket som helst af (i) til (ii), hvor polypeptidet har en sekvens som angivet i SEQ ID NO:52, eller enzymatisk aktive fragmenter deraf med alpha-amylase acitivity.
6. Isoleret, syntetisk eller rekombinant nukleinsyre ifølge krav 5, hvor alpha-amylase-aktiviteten omfatter hydrolysering af glucosidiske bindinger, og de glucosidiske bindinger eventuelt omfatter en a-1,4-glucosidisk binding eller en a-1,6-glucosidisk binding, og/eller hvor alpha-amylase-aktiviteten eventuelt omfatter hydrolysering af glucosidiske bindinger i en polysaccharid, en oligosaccharid eller en stivelse, og/eller alpha-amylase-aktiviteten omfatter spaltning af en maltose eller en D-glucose-enhed fra ikke-reducerende ende af en polysaccharid, oligosaccharid eller stivelse.
7. Fremgangsmåde til fremstilling af et rekombinant polypeptid, omfattende trinnene: (a) tilvejebringe en nukleinsyre, der er funktionsmæssigt forbundet med en promoter, hvor nukleinsyren omfatter nukleinsyresekvensen ifølge krav 1; og (b) eksprimere nukleinsyre fra trin (a) under betingelser, der muliggør eksprimering af polypeptidet, hvorved der fremstilles et rekombinant polypeptid, yderligere omfattende at transformere en værtscelle med nukleinsyren fra trin (a) efterfulgt af eksprimering af nukleinsyren fra trin (a), hvorved der fremstilles et rekombinant polypeptid i en transformeret celle.
8. Fremgangsmåde til at hydrolysere en polysaccharid, oligosaccharid eller stivelse, omfattende følgende trin: (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe en sammensætning omfattende en polysaccharid, oligosaccharid eller stivelse; hvor sammensætningen eventuelt omfatter en a-1,4-glucosidisk binding eller en a-1,6-glucosidisk binding; og (c) bringe polypeptidet fra trin (a) i kontakt med sammensætningen fra trin (b) under betingelser, hvor polypeptidet hydrolyserer polysacchariden, oligosac-chariden eller stivelsen.
9. Fremgangsmåde til at fjerne eller gøre en polysaccharid, oligosaccharid eller stivelse flydende, omfattende følgende trin: (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe en sammensætning omfattende en polysaccharid, oligosaccharid eller stivelse; og (c) bringe polypeptidet fra trin (a) i kontakt med sammensætningen fra trin (b) under betingelser, hvor polypeptidet fjerner eller gør polysacchariden, olig-osacchariden eller stivelsen flydende.
10. Fremgangsmåde til at vaske en genstand, omfattende følgende trin: (a) tilvejebringe en sammensætning omfattende polypeptidet ifølge krav 5; (b) tilvejebringe en genstand; og (c) bringe bringe polypeptidet fra trin (a) i kontakt med genstanden fra trin (b) under betingelser, hvor sammensætningen kan vaske genstanden.
11. Fremgangsmåde til hydrolyse af en polysaccharid, oligosaccharid eller stivelse i et foder eller en fødevare inden fortæring af et dyr, omfattende de følgende trin: (a) opnå et fodermateriale omfattende en stivelse, hvor polysaccharid, oligosaccharid eller stivelse i polysacchariden, oligosacchariden eller stivelsen kan hydrolyseres af polypeptidet ifølge krav 5; og (b) tilsætte polypeptidet ifølge krav 5 til foder- eller fødevarematerialet i en tilstrækkelig mængde i tilstrækkelig tid til at bevirke hydrolyse af polysacchariden, oligosacchariden eller stivelsen og dannelse af et behandlet foder eller en behandlet fødevare, og derved hydrolysere polysacchariden, oligosacchariden eller stivelsen i foderet eller fødevaren inden fortæring af dyret, hvor foderet eller fødevaren eventuelt omfatter ris, majs, byg, hvede, grøntsager eller kartoffel.
12. Fremgangsmåde til krympning af tekstiler, omfattende følgende trin: (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe stof; og (c) bringe polypeptidet fra trin (a) i kontakt med stoffet fra trin (b) under betingelser, hvor alpha-amylasen kan krympe stoffet.
13. Fremgangsmåde til behandling af lignocellulosiske fibre, omfattende følgende trin: (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe en lignocellulosisk fiber; og (c) bringe polypeptidet fra trin (a) i kontakt med fiberen fra trin (b) under betingelser, hvor polypeptidet kan behandle fiberen og derved forbedre fiberegenskaberne.
14. Fremgangsmåde til at fremstille en sirup med højt maltoseindhold eller glucoseindhold, omfattende følgende trin: (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe en sammensætning omfattende en polysaccharid, oligosac-charid eller stivelse; hvor polysacchariden, oligosacchariden eller stivelsen eventuelt er fra ris, majs, byg, hvede, grøntsager, kartoffel eller søde kartofler, og (c) bringe polypeptidet fra trin (a) i kontakt med sammensætningen fra trin (b) under betingelser, hvor polypeptidet fra trin (a) kan hydrolysere sammensætningen fra trin (b), og derved fremstille en sirup med højt maltoseindhold eller glucoseindhold.
15. Fremgangsmåde til forbedring af strømmen af polysaccharid-, oligosac-charid- eller stivelsesholdige produktionsfluider, omfattende følgende trin: (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe produktionsfluid omfattende en polysaccharid, oligosaccharid eller stivelse; hvor produktionsfluiden eventuelt er fra en underjordisk formation; og (c) bringe polypeptidet fra trin (a) i kontakt med produktionsfluiden fra trin (b) under betingelser, hvor polypeptidet kan hydrolysere polysacchariden, oligosacchariden eller stivelsen i produktionsfluiden og derved forbedre strømmen deraf ved at forøge densiteten.
16. Fremgangsmåde til ændring af viskositeten af en sammensætning, omfattende følgende trin: (i) (a) tilvejebringe en sammensætning og polypeptidet ifølge krav 5; og (b) behandle sammensætningen med polypeptidet ifølge krav 5; eller (ii) fremgangsmåden fra (i), hvor sammensætningen omfatter jord eller boreslam.
17. Fremgangsmåde til anvendelse af en alpha-amylase i brygning eller fremstilling af alkohol, omfattende følgende trin: (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe en sammensætning anvendt til brygning eller fremstilling af alkohol, omfattende en polysaccharid, oligosaccharid eller en stivelse; hvor sammensætningen, som omfatter en polysaccharid, oligosaccharid eller stivelse, eventuelt er en øl; (c) kombinere polypeptidet fra trin (a) med sammensætningen fra trin (b) under betingelser, hvor polypeptidet kan hydrolysere polysacchariden, olig-osacchariden eller stivelsen i sammensætningen, som anvendes til brygning eller produktion af alkohol.
18. Fremgangsmåde til biologisk blegning af en sammensætning, omfattende: (i) tilvejebringe en sammensætning, hvor sammensætningen er et papir- eller pulpprodukt, og polypeptidet ifølge krav 5; (ii) behandle sammensætningen med polypeptidet ifølge krav 5.
19. Fremgangsmåde til fjernelse af blæk på papir og fibre, omfattende følgende trin: (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe en sammensætning omfattende papir eller fiber; (c) bringe polypeptidet fra trin (a) i kontakt med sammensætningen fra trin (b) under betingelser, hvor polypeptidet kan fjerne blæk fra papiret eller fiberen.
20. Fremgangsmåde til fremstilling af et brændstof, omfattende: (i) (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe en sammensætning omfattende en polysaccharid, oligosaccharid eller stivelse; og (c) bringe polypeptidet fra (a) i kontakt med sammensætningen fra (b) under betingelser, hvor polypeptidet hydrolyserer polysacchariden, oligosacchariden eller stivelsen; eller (ii) fremgangsmåden fra (i), hvor polypeptidet er et termostabilt enzym; (iii) fremgangsmåden fra (i), hvor brændstoffet er ethanol-baseret.
21. Fremgangsmåde til behandling af et biomassemateriale omfattende lig-nocellulose, omfattende (i) (a) tilvejebringe en sammensætning, omfattende polypeptidet fra krav 5, og tilvejebringe et biomassemateriale; og (b) bringe sammensætningen i kontakt med biomassematerialet; (ii) fremgangsmåden fra (i), hvor biomassmaterialet omfatter eller er afledt af en landbrugsafgrøde, eller er et biprodukt af en foder- eller fødevareproduktion, eller er et lignocellulosisk affaldsprodukt, eller er en planterest eller et affaldspapir eller affaldspapirprodukt, og biomassematerialet eventuelt omfatter kartofler, sojabønne, byg, rug, majs, havre, hvede, roer eller sukkerrør; (iii) fremgangsmåden fra (i) eller (ii), hvor polypeptidet har aktivitet, som omfatter en alpha-amylase-aktivitet; (iv) fremgangsmåden fra (ii), hvor planteresten omfatter stammer, blade, bælge, skaller, kolber, træ, træsplinter, træmasse og savsmuld, eller papiraffaldet omfatter kasseret eller brugt fotokopipapir, computerprinterpapir, no-tesbogpapir, notesblokpapir, skrivemaskinepapir, aviser, ugeblade, karton og papirbaserede indpakningsmaterialer; eller (v) fremgangsmåden fra (i) til (iv), hvor behandlingen af biomassematerialet genererer en bioethanol, biopropanol, biobutanol eller en biodiesel; (vi) fremgangsmåden fra (i) til (v), hvor biomassematerialet omfatter en lig-nocellulose.
22. Fremgangsmåde til fremstilling af bioethanol, biopropanol, biobutanol eller en biodiesel, omfattende (i) (a) tilvejebringe polypeptidet ifølge krav 5, og tilvejebringe en sammensætning omfattende en polysaccharid eller oligosaccharid; og (b) bringe sammensætningen omfattende en polysaccharid eller oligosaccharid i kontakt med polypeptidet ifølge krav 5; (ii) fremgangsmåden fra (i), hvor sammensætningen omfattende en polysaccharid eller oligosaccharid omfatter en plante, et planteprodukt eller plantede-ri vat; (iii) fremgangsmåden fra (ii), hvor planten eller planteproduktet omfatter rørsukkerplanter eller -planteprodukter, roer eller sukkerroer, hvede, majs, sojabønner, kartoffel, ris eller byg; (iv) fremgangsmåden fra en hvilken som helst af (i) til (iii), hvor polypeptidet har aktivitet omfattende en alpha-amylase-aktivitet; eller (v) fremgangsmåden fra en hvilken som helst af (i) til (iv), hvor polysacchari-den eller oligosacchariden omfatter et fermenterbart sukker.
23. Fremgangsmåde til fremstilling af et brændstof, omfattende (i) (a) tilvejebringe polypeptidet ifølge krav 5 og tilvejebringe en sammensætning omfattende et fermenterbart sukker; og (b) bringe sammensætningen omfattende et fermenterbart sukker i kontakt med polypeptider ifølge krav 5; (ii) fremgangsmåden fra (i), hvor sammensætningen omfattende et fermenterbart sukker omfatter en plante, et planteprodukt eller plantederivat; (iii) fremgangsmåden fra (ii), hvor planten eller planteproduktet omfatter rørsukkerplanter eller -planteprodukter, roer eller sukkerroer, hvede, majs, sojabønner, kartoffel, ris eller byg; (iv) fremgangsmåde fra en hvilken som helst af (i) til (iii), hvor polypeptidet har aktivitet omfattende en alpha-amylase-aktivitet; eller (v) fremgangsmåde fra en hvilken som helst af (i) til (iv), hvor brændstoffet omfatter en bioethanol eller en benzin-ethanol-blanding eller omfatter en bio-ethanol, biopropanol, biobutanol eller en biodiesel.
24. Fremgangsmåde til fremstilling af sukker, hvilken fremgangsmåde omfatter: (i) (a) tilvejebringe polypeptidet ifølge krav 5; (b) tilvejebringe en sammensætning omfattende en polysaccharid eller en oligosaccharid; og (c) bringe sammensætningen fra trin (b) i kontakt med polypeptidet fra trin (a) og derved generere sukker; (ii) fremgangsmåden fra (i), hvor sammensætningen, som omfatter en polysaccharid, omfatter en stivelse; (iii) fremgangsmåden fra en hvilken som helst af (i) eller (ii), hvor sukkeret er et fermenterbart sukker.
25. Sammensætning omfattende polypeptidet ifølge krav 5, hvor sammensætningen er udvalgt blandt: et detergent, et foder eller en fødevare, tekstil eller stof, papir eller papirprodukt eller papirmasse, væske eller sirup med højt indhold af maltose eller glucose, en sammensætning til forhindring af brødtørring, en alkoholisk drik, en øl, en farmaceutisk sammensætning, et mundhygiejneprodukt, en tandpasta, en tandcreme, en gel eller et tandpulver, et tandplejemiddel, et mundskyllemiddel, en formulering til rensning før og efter børstning, tyggegummi, en pastil eller et bolsje, en olieboringsfluid, en biologisk blegningsopløsning, et desinficerende middel, et middel til biologisk forsvar eller biologisk afgiftning, et mejeriprodukt eller et biomassemateriale.
26. Sammensætning med forsinket frigivelse eller kontrolleret frigivelse omfattende polypeptidet ifølge krav 5, omfattende (a) en ønsket ingrediens, coatet med en latexpolymer-coating; (b) sammensætningen med forsinket frigivelse eller kontrolleret frigivelse fra (a), hvor den ønskede ingrediens omfatter et enzym; (c) sammensætningen med forsinket frigivelse eller kontrolleret frigivelse fra (a) eller (b), hvor den ønskede ingrediens omfatter et lille molekyle, et lægemiddel, en polysaccharid, en lipid, en nukleinsyre, et vitamin, antibiotika eller en insektgift; (d) sammensætningen med forsinket frigivelse eller kontrolleret frigivelse fra (a), (b) eller (c), hvor den ønskede ingrediens omfatter en pellet eller en matrix; (e) sammensætningen med forsinket frigivelse eller kontrolleret frigivelse fra en hvilken som helst af (a) til (d), hvor pellet eller matrix omfatter spiseligt materiale; (f) sammensætningen med forsinket frigivelse eller kontrolleret frigivelse fra en hvilken som helst af (a) til (e), hvor latexpolymer-coatingen omfatter en latex-maling; eller (g) sammensætningen med forsinket frigivelse eller kontrolleret frigivelse fra en hvilken som helst af (a) til (f), hvor latexpolymer-coatingen omfatter (meth)acrylat, vinylacetat, styren, ethylen, vinylchlorid, butadien, vinyliden-chlorid, vinylversatat, vinylpropionat, t-butylacrylat, acrylonitril, neopren, ma-leat, fumarat eller en kombination deraf eller et derivat deraf.
DK12152656.0T 2006-12-21 2007-12-21 Amylaser og glucoamylaser, nukleinsyrer, som koder for dem, og fremgangsmåder til fremstilling og anvendelse deraf DK2479266T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87706806P 2006-12-21 2006-12-21
US89282307P 2007-03-02 2007-03-02
EP07869797.6A EP2069490B2 (en) 2006-12-21 2007-12-21 Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them

Publications (1)

Publication Number Publication Date
DK2479266T3 true DK2479266T3 (da) 2016-06-20

Family

ID=39563240

Family Applications (4)

Application Number Title Priority Date Filing Date
DK16180480.2T DK3101128T3 (da) 2006-12-21 2007-12-21 Amylaser og glucoamylaser, nukleinsyrer, der koder for disse, og fremgangsmåder til fremstillling og anvendelse deraf
DK12152662.8T DK2479267T3 (da) 2006-12-21 2007-12-21 Amylaser og glucoamylaser, nukleinsyrer, som koder for dem, og fremgangsmåder til fremstilling og anvendelse deraf
DK12152656.0T DK2479266T3 (da) 2006-12-21 2007-12-21 Amylaser og glucoamylaser, nukleinsyrer, som koder for dem, og fremgangsmåder til fremstilling og anvendelse deraf
DK07869797.6T DK2069490T4 (da) 2006-12-21 2007-12-21 Amylaser og glucoamylaser, nukleinsyrer, der koder for dem, og fremgangsmåder til fremstilling og anvendelse deraf

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK16180480.2T DK3101128T3 (da) 2006-12-21 2007-12-21 Amylaser og glucoamylaser, nukleinsyrer, der koder for disse, og fremgangsmåder til fremstillling og anvendelse deraf
DK12152662.8T DK2479267T3 (da) 2006-12-21 2007-12-21 Amylaser og glucoamylaser, nukleinsyrer, som koder for dem, og fremgangsmåder til fremstilling og anvendelse deraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK07869797.6T DK2069490T4 (da) 2006-12-21 2007-12-21 Amylaser og glucoamylaser, nukleinsyrer, der koder for dem, og fremgangsmåder til fremstilling og anvendelse deraf

Country Status (12)

Country Link
US (4) US8343747B2 (da)
EP (5) EP3540053B1 (da)
CN (1) CN101646767B (da)
AU (1) AU2007336732B2 (da)
BR (1) BRPI0719449A2 (da)
CA (2) CA2673525C (da)
DK (4) DK3101128T3 (da)
ES (4) ES2734114T3 (da)
HU (2) HUE027892T2 (da)
MX (1) MX2009006782A (da)
PL (4) PL2479266T3 (da)
WO (1) WO2008080093A2 (da)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9816119B2 (en) 2008-02-29 2017-11-14 Syngenta Participations Ag Methods for starch hydrolysis
US7931784B2 (en) * 2008-04-30 2011-04-26 Xyleco, Inc. Processing biomass and petroleum containing materials
US8667706B2 (en) * 2008-08-25 2014-03-11 David N. Smith Rotary biomass dryer
ES2667812T3 (es) * 2008-11-20 2018-05-14 Novozymes Inc. Polipéptidos que tienen actividad potenciadora amilolítica y polinucleótidos que codifican los mismos
US10221405B2 (en) 2008-11-20 2019-03-05 Novozymes, Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
US9506046B2 (en) 2008-11-20 2016-11-29 Novozymes, Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
US8556634B2 (en) * 2009-01-26 2013-10-15 Tactical Care Concepts, Llc Self-contained needle insertion training system
WO2010091221A1 (en) * 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
JP5827227B2 (ja) * 2009-08-19 2015-12-02 デュポン ニュートリション バイオサイエンシーズ エーピーエスＤｕＰｏｎｔ Ｎｕｔｒｉｔｉｏｎ Ｂｉｏｓｃｉｅｎｃｅｓ ＡｐＳ グルコアミラーゼの変異体
US20130071884A1 (en) 2009-11-06 2013-03-21 Agrivida, Inc. Plants expressing cell wall degrading enzymes and expression vectors
WO2011128712A1 (en) * 2010-04-12 2011-10-20 Stellenbosch University Biofuel production
US9617527B2 (en) 2010-04-14 2017-04-11 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
US8906235B2 (en) * 2010-04-28 2014-12-09 E I Du Pont De Nemours And Company Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth
CA2803868A1 (en) 2010-06-25 2011-12-29 Agrivida, Inc. Plants with altered levels of vegetative starch
US9598700B2 (en) * 2010-06-25 2017-03-21 Agrivida, Inc. Methods and compositions for processing biomass with elevated levels of starch
US10443068B2 (en) 2010-06-25 2019-10-15 Agrivida, Inc. Plants with engineered endogenous genes
GB201011513D0 (en) * 2010-07-08 2010-08-25 Danisco Method
CN101930502B (zh) * 2010-09-03 2011-12-21 深圳华大基因科技有限公司 表型基因的检测及生物信息分析的方法及系统
CN106244622B (zh) 2011-03-07 2020-06-12 谷万达公司 在工程植物中表达多种蛋白的表达盒和表达载体及制备工程植物和生产可溶性糖的方法
EP2697356B1 (en) * 2011-04-15 2020-06-10 Novozymes A/S Method for production of brewers wort
US9102860B2 (en) * 2011-06-16 2015-08-11 Baker Hughes Incorporated Method of inhibiting or controlling release of well treatment agent
EP2748188A4 (en) 2011-08-26 2015-03-18 Novozymes As POLYPEPTIDES WITH GLUCCOAMYLASE ACTIVITY AND THESE CODING POLYNUCLEOTIDES
US9650620B2 (en) * 2011-08-26 2017-05-16 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
JP2015518470A (ja) 2012-03-26 2015-07-02 プロニュートリア・インコーポレイテッドＰｒｏｎｕｔｒｉａ， Ｉｎｃ． 栄養タンパク質および方法
JP2015519878A (ja) 2012-03-26 2015-07-16 プロニュートリア・インコーポレイテッドＰｒｏｎｕｔｒｉａ， Ｉｎｃ． 栄養断片、タンパク質、および方法
WO2013148329A1 (en) 2012-03-26 2013-10-03 Pronutria, Inc. Charged nutritive proteins and methods
WO2013148330A1 (en) 2012-03-26 2013-10-03 Pronutria, Inc. Nutritive fragments, proteins and methods
CA2869047C (en) 2012-03-30 2022-11-01 Novozymes North America, Inc. Processes of producing fermentation products
ES2935920T3 (es) * 2012-03-30 2023-03-13 Novozymes North America Inc Procesos de elaboración de productos de fermentación
JP2015518707A (ja) 2012-05-11 2015-07-06 ダニスコ・ユーエス・インク 糖化のための、ａｓｐｅｒｇｉｌｌｕｓｃｌａｖａｔｕｓ由来アルファアミラーゼの使用
CN102719419B (zh) * 2012-07-02 2013-10-09 武汉新华扬生物股份有限公司 一种可以降解生淀粉的糖化酶glad3及其基因和应用
EP2906692A1 (en) * 2012-10-10 2015-08-19 Danisco US Inc. Method of using alpha-amylase from talaromyces emersonii for saccharification
WO2014092961A1 (en) * 2012-12-11 2014-06-19 Danisco Us Inc. A process for producing high glucose compositions by simultaneous liquefaction and saccharification of starch substrates
DK2935574T3 (da) 2012-12-17 2020-02-03 Novozymes As Alfaamylaser og polynukleotider, som koder for dem
CA2896251A1 (en) 2013-01-11 2014-07-17 Dsm Ip Assets B.V. Process for enzymatic hydrolysis of lignocellulosic material
CN103114049B (zh) * 2013-01-29 2015-04-15 华东理工大学 一种共表达葡萄糖淀粉酶和α-淀粉酶的重组毕赤酵母菌株及其构建方法,以及混合酶制剂
EP2772545A1 (en) * 2013-03-01 2014-09-03 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Starch active proteins
US9850512B2 (en) 2013-03-15 2017-12-26 The Research Foundation For The State University Of New York Hydrolysis of cellulosic fines in primary clarified sludge of paper mills and the addition of a surfactant to increase the yield
GB2527479B (en) 2013-04-26 2020-10-14 Desbarats Andrew A proppant immobilized enzyme and a viscofied fracture fluid
US20170121643A1 (en) * 2013-06-21 2017-05-04 Novozymes A/S Polypeptides having amylase activity and polynucleotides encoding same
EP3048904A2 (en) 2013-09-25 2016-08-03 Pronutria Biosciences, Inc. Compositions and formulations for treatment of gastrointestinal tract malabsorption diseases and inflammatory conditions and methods of production and use thereof
EP3052129A2 (en) 2013-09-30 2016-08-10 Daiichi Sankyo Company, Limited Protein biomarker and uses thereof
US10227523B2 (en) 2013-11-26 2019-03-12 Advanced Enzyme Systems, Llc Glycosyl hydrolase enzymes in high temperature industrial processes
CN103760331B (zh) * 2014-02-11 2016-05-04 郑州安图生物工程股份有限公司 精浆联检试剂盒
US9951363B2 (en) 2014-03-14 2018-04-24 The Research Foundation for the State University of New York College of Environmental Science and Forestry Enzymatic hydrolysis of old corrugated cardboard (OCC) fines from recycled linerboard mill waste rejects
JP6548679B2 (ja) 2014-07-08 2019-07-24 キャラヴァン イングリーディエンツ インク． 糖を生成しかつテクスチャーを改善するベーカリー方法およびそれから形成される製品
CN113403357B (zh) * 2014-12-19 2024-10-18 丹尼斯科美国公司 葡糖淀粉酶共混物
WO2016160584A1 (en) * 2015-03-27 2016-10-06 Cargill, Incorporated Glucoamylase-modified yeast strains and methods for bioproduct production
US11286621B2 (en) 2015-08-14 2022-03-29 Basf Se Aqueous surface treatment composition for paper and board
US11332728B2 (en) 2015-09-04 2022-05-17 Lallemand Hungary Liquidity Management Llc Yeast strains for the expression and secretion of heterologous proteins at high temperatures
CN108431229A (zh) 2015-12-17 2018-08-21 嘉吉公司 糖转运蛋白修饰的酵母菌株和用于生物制品生产的方法
WO2017112635A1 (en) * 2015-12-21 2017-06-29 Danisco Us Inc Improved granular starch conversion enzymes and methods
JP7202890B2 (ja) * 2016-02-19 2023-01-12 ノース カロライナ ステート ユニバーシティ 生理学的応答性マイクロニードル送達システムに関連する方法及び組成物
CN105885813B (zh) * 2016-04-18 2018-11-20 中国石油集团渤海钻探工程有限公司 氯化钠盐水修井液用缓蚀剂
DE102016209880A1 (de) * 2016-06-06 2017-12-07 Henkel Ag & Co. Kgaa Neue Amylasen
CN109661403A (zh) 2016-08-05 2019-04-19 嘉吉公司 前导序列修饰的葡糖淀粉酶多肽和具有增强的生物产物产生的工程化的酵母菌株
US9598680B1 (en) * 2016-08-05 2017-03-21 Fornia Biosolutions, Inc. G16 glucoamylase compositions and methods
GB201620658D0 (en) * 2016-12-05 2017-01-18 Univ Stellenbosch Recombinant yeast and use thereof
US12110531B2 (en) * 2017-06-16 2024-10-08 Danstar Ferment Ag Method for increasing oil yield during ethanol production
US10943507B2 (en) 2017-07-27 2021-03-09 Mochtech, Llc Self-contained multipurpose medical training system and components
WO2019047199A1 (en) * 2017-09-11 2019-03-14 Danisco Us Inc. GLUCOAMYLASE AND METHODS OF USE THEREOF
ES3027937T3 (en) * 2017-09-29 2025-06-17 Int N&H Denmark Aps Production of brewer's wort having increased fermentable sugars
CN111278970B (zh) 2017-10-25 2024-09-27 巴斯夫欧洲公司 β-淀粉酶
EP3710580A1 (en) * 2017-11-14 2020-09-23 Danisco US Inc. Alpha-amylase, composition and method
CN108304933A (zh) * 2018-01-29 2018-07-20 北京师范大学 一种知识库的补全方法及补全装置
CA3093378A1 (en) * 2018-03-09 2019-09-12 Danisco Us Inc Glucoamylases and methods of use thereof
WO2019175807A1 (en) * 2018-03-13 2019-09-19 Lallemand Hungary Liquidity Management Llc Yeast expressing thermostable alpha-amylases for hydrolysis of starch
CN108509694B (zh) * 2018-03-13 2022-02-18 西安石油大学 一种基于bp神经网络的支撑剂铺置形态预测方法
US11732250B2 (en) 2018-04-26 2023-08-22 Basf Se Lipase enzymes
WO2019211143A1 (en) 2018-05-03 2019-11-07 Basf Se Amylase enzymes
CN108611339B (zh) * 2018-05-11 2021-05-25 中国农业科学院北京畜牧兽医研究所 葡萄糖淀粉酶TlGa15及其基因和应用
US12351841B2 (en) 2018-05-29 2025-07-08 Basf Se Amylase enzymes
EP3818165A2 (en) * 2018-07-04 2021-05-12 Danisco US Inc. Glucoamylases and methods of use, thereof
CN120795059A (zh) 2018-08-27 2025-10-17 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
US11036200B2 (en) 2018-10-15 2021-06-15 Coretigo Ltd. Last resort frequency mechanism in a wireless communication system
CN109430783B (zh) * 2018-11-12 2023-01-31 湖南德海制药有限公司 一种花粉的酶解方法
CN109486819B (zh) * 2018-11-23 2021-04-30 中国热带农业科学院三亚研究院 木薯u6启动子基因及应用
CN109549038A (zh) * 2018-12-28 2019-04-02 中华全国供销合作总社济南果品研究院 综合利用甘薯多级联产淀粉和浓缩清汁的工艺
WO2020169563A1 (en) 2019-02-20 2020-08-27 Basf Se Industrial fermentation process for bacillus using defined medium and magnesium feed
US20220186234A1 (en) 2019-02-20 2022-06-16 Basf Se Industrial Fermentation Process for Bacillus Using Defined Medium and Trace Element Feed
US11343672B2 (en) 2019-02-20 2022-05-24 Coretigo Ltd. Secure communication encryption and decryption mechanism in a wireless communication system
EP3938504A1 (en) 2019-03-11 2022-01-19 Basf Se Amylases and methods for making and using them
WO2020193534A2 (en) 2019-03-25 2020-10-01 Basf Se Amylase enzymes
WO2020193532A1 (en) 2019-03-25 2020-10-01 Basf Se Cleaning composition having amylase enzymes
US20220162576A1 (en) 2019-03-25 2022-05-26 Basf Se Amylase enzymes
CN118086254A (zh) 2019-04-23 2024-05-28 巴斯夫欧洲公司 β-淀粉酶变体
EP3983425B1 (en) 2019-06-13 2025-10-01 Basf Se Method of recovering a protein from fermentation broth using a divalent cation
WO2021004830A1 (en) 2019-07-05 2021-01-14 Basf Se Industrial fermentation process for microbial cells using a fed-batch pre-culture
BR112022000573A2 (pt) 2019-08-22 2022-03-15 Basf Se Polipeptídeo isolado, sintético ou recombinante com atividade alfa-amilase, ácido nucleico isolado, sintético ou recombinante, construto de ácido nucleico, vetor de expressão, célula hospedeira, composição, método para produzir polipeptídeo isolado, sintético ou recombinante, método para preparar uma massa ou um produto de panificação, e, métodos para usar o polipeptídeo isolado, sintético ou recombinante e um domínio c de uma primeira amilase
CN110540695A (zh) * 2019-09-05 2019-12-06 东莞市和信包装制品有限公司 一种可降解环保袋及制备方法
FI130583B (en) * 2019-10-11 2023-11-23 Fazer Ab Oy Karl Non-dairy crumb and method for its manufacture
BR112022008292A2 (pt) 2019-11-08 2022-07-26 Novozymes As Composição enzimática líquida, e, método para produzir um mosto para fabricação de cerveja
CN111220604B (zh) * 2019-12-06 2022-03-15 东北农业大学 一种肉制品中总淀粉含量的测定方法
CN111139275B (zh) * 2019-12-31 2021-12-21 山东省药学科学院 一种改进的利用酵母制备贻贝寡糖的方法
CN111244483B (zh) * 2020-01-15 2021-06-15 先进能源产业研究院(广州)有限公司 一种N-P共掺杂多孔碳包覆NiCo2O4的氧还原催化剂及其制法
WO2022040022A1 (en) * 2020-08-18 2022-02-24 St. Jude Children's Research Hospital, Inc. Use of amylase or maltose to treat or prevent neurodegeneration
WO2022087331A1 (en) * 2020-10-22 2022-04-28 Basf Se A method for measuring concentration of human milk oligosaccharides (hmo) molecules using glocometer
CN112697926A (zh) * 2020-12-31 2021-04-23 华仁药业股份有限公司 一种糖盐水饮料中海藻糖含量的检测方法
CN113552249A (zh) * 2021-06-24 2021-10-26 上海交通大学 淀粉壳层蛋白的提取鉴定方法
CA3225830A1 (en) * 2021-07-12 2023-01-19 Joshua W. Heyen Strains of saccharomyces cerevisiae that exhibit an increased ability to ferment oligosaccharides into ethanol without supplemental glucoamylase and methods of making and using the sam
US20250311734A1 (en) 2022-05-14 2025-10-09 Novozymes A/S Compositions and Methods for Preventing, Treating, Suppressing and/or Eliminatting Phytopathogenic Infestations and Infections
CN114645005B (zh) * 2022-05-18 2022-08-26 中国科学院地理科学与资源研究所 一种假单胞菌及其应用
CN115184299B (zh) * 2022-06-01 2024-08-02 广东惠尔泰生物科技有限公司 一种基于近红外光谱检测固定化脂肪酶酶蛋白含量的方法

Family Cites Families (225)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1138A (en) 1839-04-29 Machine for plaiting or dressing sawed shingles
US2615810A (en) 1948-03-04 1952-10-28 Wallerstein Company Retarding the staling of bakery products
US3026205A (en) 1959-08-19 1962-03-20 Baxter Laboratories Inc Process of producing baked confections and the products resulting therefrom by alpha amylase
US3847740A (en) 1972-10-02 1974-11-12 Cpc International Inc Process for the production of levulose-bearing syrups
US4099583A (en) 1977-04-11 1978-07-11 Exxon Production Research Company Gas lift system for marine drilling riser
US5366558A (en) 1979-03-23 1994-11-22 Brink David L Method of treating biomass material
WO1981000857A1 (fr) 1979-09-28 1981-04-02 Vsesoyuzny Ni Biotek Inst Procede de production d'alcool ethylique a partir d'un materiau d'amidon brut
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
JPS5823799A (ja) 1981-08-03 1983-02-12 株式会社林原生物化学研究所 高純度マルト−スの製造方法
JPS5872598A (ja) 1981-10-26 1983-04-30 Hayashibara Biochem Lab Inc 高純度イソマルト−スの製造方法
US4535060A (en) 1983-01-05 1985-08-13 Calgene, Inc. Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use
US4557927A (en) 1983-03-10 1985-12-10 Kabushiki Kaisha Hoyashibara Food products and process for producing same
US5021246A (en) 1984-03-30 1991-06-04 Anheuser-Busch, Incorporated Step mashing process for producing low alcohol beer
US5087571A (en) 1984-06-22 1992-02-11 President And Fellows Of Harvard College Method for providing a cell culture from a transgenic non-human mammal
US4943674A (en) 1987-05-26 1990-07-24 Calgene, Inc. Fruit specific transcriptional factors
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DE3546807C2 (da) 1985-03-30 1991-03-28 Marc Genf/Geneve Ch Ballivet
NZ217113A (en) 1985-08-07 1988-06-30 Monsanto Co Production of eucaryotic plants which are glyphosate resistant, vectors (transformation and expression), chimeric gene and plant cells
JPS62104580A (ja) 1985-10-30 1987-05-15 Kunio Yamane 高耐熱性酵素発現ｄｎａ
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
US4962028A (en) 1986-07-09 1990-10-09 Dna Plant Technology Corporation Plant promotors
DE3623533A1 (de) 1986-07-12 1988-01-21 Beiersdorf Ag Pyrido(1,8)naphthyridinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
NZ221259A (en) 1986-07-31 1990-05-28 Calgene Inc Seed specific transcriptional regulation
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5015580A (en) 1987-07-29 1991-05-14 Agracetus Particle-mediated transformation of soybean plants and lines
US5573933A (en) 1987-04-14 1996-11-12 Luminis Pty, Ltd. Transgenic pigs
US4788066A (en) 1987-12-14 1988-11-29 Grain Processing Corporation Preparation of low alcohol beer
US6054270A (en) 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US5700637A (en) 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
NZ230375A (en) 1988-09-09 1991-07-26 Lubrizol Genetics Inc Synthetic gene encoding b. thuringiensis insecticidal protein
US5217879A (en) 1989-01-12 1993-06-08 Washington University Infectious Sindbis virus vectors
BR9000379A (pt) 1989-01-31 1990-12-04 Union Carbide Chem Plastic Polissacarideo soluvel em agua,processo para producao de um polissacarideo soluvel em agua,composicao de latex e processo para producao de uma composicao de latex
EP1103616A3 (en) 1989-02-24 2001-06-27 Monsanto Company Synthetic plant genes and method for preparation
US5527681A (en) 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5800992A (en) 1989-06-07 1998-09-01 Fodor; Stephen P.A. Method of detecting nucleic acids
US4940935A (en) 1989-08-28 1990-07-10 Ried Ashman Manufacturing Automatic SMD tester
DK474589D0 (da) 1989-09-27 1989-09-27 Novo Nordisk As Fremgangsmaade til fremstilling af bageriprodukter
US5641876A (en) 1990-01-05 1997-06-24 Cornell Research Foundation, Inc. Rice actin gene and promoter
US5589583A (en) 1990-01-11 1996-12-31 Monsanto Company Plant promoter
AU7791991A (en) 1990-04-24 1991-11-11 Stratagene Methods for phenotype creation from multiple gene populations
US5326477A (en) 1990-05-07 1994-07-05 Bio-Sep, Inc. Process for digesting solid waste
WO1991019810A1 (en) 1990-06-15 1991-12-26 California Biotechnology Inc. Transgenic non-human mammal displaying the amyloid-forming pathology of alzheimer's disease
US5639949A (en) 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
IE913215A1 (en) 1990-09-13 1992-02-25 Gist Brocades Nv Transgenic plants having a modified carbohydrate content
ATE318318T1 (de) 1990-11-23 2006-03-15 Bayer Bioscience Nv Verfahren zur transformation monokotyler pflanzen
US6582908B2 (en) 1990-12-06 2003-06-24 Affymetrix, Inc. Oligonucleotides
DE69131017T2 (de) 1990-12-20 1999-07-15 Ixsys, Inc., San Diego, Calif. Optimierung von bindenden proteinen
NL9100050A (nl) 1991-01-11 1992-08-03 Heineken Technische Beheer Bv Werkwijze voor het continu bereiden van wort.
US5405624A (en) 1991-02-14 1995-04-11 Bio-Technical Resources Process for producing a product with an intensified beer flavor
US6110700A (en) 1991-03-11 2000-08-29 The General Hospital Corporation PRAD1 cyclin and its cDNA
US5922854A (en) 1991-06-14 1999-07-13 Kumar; Ramesh Purifying Human Hemogloblin from transgenic pig red cells and plasmids containing pig globin nucleic acids
WO1993000426A1 (en) 1991-06-25 1993-01-07 Novo Nordisk A/S Mammalian pancreatic lipase and variant thereof
GB9114259D0 (en) 1991-07-02 1991-08-21 Ici Plc Plant derived enzyme and dna sequences
CA2075135A1 (en) 1991-08-02 1993-02-03 David E. Ellis Particle-mediated transformation of gymnosperms
GB9304200D0 (en) 1993-03-02 1993-04-21 Sandoz Ltd Improvements in or relating to organic compounds
US5994629A (en) 1991-08-28 1999-11-30 Novartis Ag Positive selection
UA48104C2 (uk) 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
US5632957A (en) 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
JPH05236997A (ja) 1992-02-28 1993-09-17 Hitachi Ltd ポリヌクレオチド捕捉用チップ
GB9216151D0 (en) 1992-07-29 1992-09-09 Ici Plc Containment of plant germplasm
AU5676394A (en) 1992-11-20 1994-06-22 Agracetus, Inc. Transgenic cotton plants producing heterologous bioplastic
ATE182359T1 (de) 1992-12-28 1999-08-15 Hayashibara Biochem Lab Nichtreduzierendes saccharidbildendes enzym, und dessen herstellung und verwendungen
US5762991A (en) 1992-12-31 1998-06-09 Metalgesellschaft Aktiengesellschaft Continous process of producing beer
DE69424861T2 (de) 1993-02-26 2000-12-28 Calgene Llc., Davis Geminivirus-basiertes-genexpressionsystem
JP3559585B2 (ja) 1993-06-03 2004-09-02 株式会社林原生物化学研究所 トレハロース遊離酵素とその製造方法並びに用途
AU7925094A (en) 1993-09-30 1995-04-18 Agracetus, Inc. Transgenic cotton plants producing heterologous peroxidase
EP0648843A1 (en) 1993-10-01 1995-04-19 Takara Shuzo Co. Ltd. DNA encoding a hyperthermostable alpha-amylase
US6045996A (en) 1993-10-26 2000-04-04 Affymetrix, Inc. Hybridization assays on oligonucleotide arrays
US6468742B2 (en) 1993-11-01 2002-10-22 Nanogen, Inc. Methods for determination of single nucleic acid polymorphisms using bioelectronic microchip
US5965452A (en) 1996-07-09 1999-10-12 Nanogen, Inc. Multiplexed active biologic array
DK131193D0 (da) 1993-11-23 1993-11-23 Novo Nordisk As
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5834252A (en) 1995-04-18 1998-11-10 Glaxo Group Limited End-complementary polymerase reaction
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US5639940A (en) 1994-03-03 1997-06-17 Pharmaceutical Proteins Ltd. Production of fibrinogen in transgenic animals
WO1995024488A1 (en) 1994-03-09 1995-09-14 Abbott Laboratories Transgenic animals producing oligosaccharides and glycoconjugates
AU694181B2 (en) 1994-03-09 1998-07-16 Abbott Laboratories Humanized milk
CA2186592C (en) 1994-03-29 2008-02-19 Helle Outtrup Alkaline bacillus amylase
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5750870A (en) 1994-06-17 1998-05-12 Agritope, Inc. Plant genetic transformation methods and transgenic plants
US5582681A (en) 1994-06-29 1996-12-10 Kimberly-Clark Corporation Production of soft paper products from old newspaper
US5959171A (en) 1994-08-17 1999-09-28 Pharming B.V. Method for the production of biologically active polypeptides in a mammal's
JPH10504964A (ja) 1994-09-01 1998-05-19 メルク エンド カンパニー インコーポレーテッド 家族性型ヒトアミロイド前駆タンパク質を発現するトランスジェニック動物
US5795737A (en) 1994-09-19 1998-08-18 The General Hospital Corporation High level expression of proteins
US6111166A (en) 1994-09-19 2000-08-29 Medarex, Incorporated Transgenic mice expressing human Fcα and β receptors
US5880327A (en) 1994-09-21 1999-03-09 American National Red Cross Transgenic mammals expressing human coagulation factor VIII
US5556752A (en) 1994-10-24 1996-09-17 Affymetrix, Inc. Surface-bound, unimolecular, double-stranded DNA
US6187992B1 (en) 1994-12-05 2001-02-13 Merck & Co., Inc. Transgenic mouse having a disrupted amyloid precursor protein gene
US5830645A (en) 1994-12-09 1998-11-03 The Regents Of The University Of California Comparative fluorescence hybridization to nucleic acid arrays
US5633440A (en) 1994-12-20 1997-05-27 Dna Plant Technology Corporation P119 promoters and their uses
US5705369A (en) 1994-12-27 1998-01-06 Midwest Research Institute Prehydrolysis of lignocellulose
US6093562A (en) 1996-02-05 2000-07-25 Novo Nordisk A/S Amylase variants
US5959098A (en) 1996-04-17 1999-09-28 Affymetrix, Inc. Substrate preparation process
ES2237764T3 (es) 1995-03-03 2005-08-01 Syngenta Participations Ag Control de la expresion genica en plantas por transactivacion mediada por un receptor en presencia de un ligando quimico.
US5610225A (en) 1995-05-03 1997-03-11 National Starch And Chemical Investment Holding Corporation Latex paints which are free of volatile coalescents and freeze-thaw additives
AU5996996A (en) 1995-06-02 1996-12-18 Novo Nordisk A/S Al/fe-treatment of a protein solution, followed by membrane concentration
JPH10510433A (ja) 1995-06-06 1998-10-13 アイシス・ファーマシューティカルス・インコーポレーテッド 高いキラル純度のホスホロチオエート結合を有するオリゴヌクレオチド
US5736499A (en) 1995-06-06 1998-04-07 Genencor International, Inc. Mutant A-amylase
US5856174A (en) 1995-06-29 1999-01-05 Affymetrix, Inc. Integrated nucleic acid diagnostic device
US5985662A (en) 1995-07-13 1999-11-16 Isis Pharmaceuticals Inc. Antisense inhibition of hepatitis B virus replication
US6057103A (en) 1995-07-18 2000-05-02 Diversa Corporation Screening for novel bioactivities
US5958672A (en) 1995-07-18 1999-09-28 Diversa Corporation Protein activity screening of clones having DNA from uncultivated microorganisms
WO1997004160A1 (en) 1995-07-19 1997-02-06 Novo Nordisk A/S Treatment of fabrics
JPH09173077A (ja) 1995-07-20 1997-07-08 Tadayuki Imanaka 超耐熱性酸性α−アミラーゼおよび該α−アミラーゼ産生遺伝子を含むＤＮＡ断片
WO1997016533A1 (en) 1995-10-31 1997-05-09 The Regents Of The University Of California Mammalian artificial chromosomes and methods of using same
US6171820B1 (en) 1995-12-07 2001-01-09 Diversa Corporation Saturation mutagenesis in directed evolution
US6361974B1 (en) 1995-12-07 2002-03-26 Diversa Corporation Exonuclease-mediated nucleic acid reassembly in directed evolution
US5939250A (en) 1995-12-07 1999-08-17 Diversa Corporation Production of enzymes having desired activities by mutagenesis
US5830696A (en) 1996-12-05 1998-11-03 Diversa Corporation Directed evolution of thermophilic enzymes
US6358709B1 (en) 1995-12-07 2002-03-19 Diversa Corporation End selection in directed evolution
US6537776B1 (en) 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
US5965408A (en) 1996-07-09 1999-10-12 Diversa Corporation Method of DNA reassembly by interrupting synthesis
US6479258B1 (en) 1995-12-07 2002-11-12 Diversa Corporation Non-stochastic generation of genetic vaccines
US6740506B2 (en) 1995-12-07 2004-05-25 Diversa Corporation End selection in directed evolution
US6022963A (en) 1995-12-15 2000-02-08 Affymetrix, Inc. Synthesis of oligonucleotide arrays using photocleavable protecting groups
US6013440A (en) 1996-03-11 2000-01-11 Affymetrix, Inc. Nucleic acid affinity columns
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
US6025155A (en) 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US5697987A (en) 1996-05-10 1997-12-16 The Trustees Of Princeton University Alternative fuel
CN1222938A (zh) 1996-05-14 1999-07-14 金克克国际有限公司 经修饰具有改变了的钙离子吉合性质的α－淀粉酶
US6197070B1 (en) 1996-05-15 2001-03-06 The Procter & Gamble Company Detergent compositions comprising alpha combination of α-amylases for malodor stripping
US5789228A (en) 1996-05-22 1998-08-04 Diversa Corporation Endoglucanases
AU3568897A (en) 1996-06-07 1998-01-05 Eos Biotechnology, Inc. Immobilised linear oligonucleotide arrays
WO1998006892A1 (en) 1996-08-16 1998-02-19 International Paper Company Enzymatic freeness enhancement
US6326341B1 (en) 1996-09-11 2001-12-04 The Procter & Gamble Company Low foaming automatic dishwashing compositions
WO1998011235A2 (en) 1996-09-12 1998-03-19 Novartis Ag Transgenic plants expressing cellulolytic enzymes
AU4550997A (en) 1996-10-11 1998-05-11 Novo Nordisk A/S Cellulose binding domains (cbds) for oral care products
US6069122A (en) 1997-06-16 2000-05-30 The Procter & Gamble Company Dishwashing detergent compositions containing organic diamines for improved grease cleaning, sudsing, low temperature stability and dissolution
AU743305C (en) 1997-01-17 2006-03-30 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
DE19703364A1 (de) 1997-01-30 1998-08-06 Henkel Ecolab Gmbh & Co Ohg Pastenförmiges Wasch- und Reinigungsmittel
US5881826A (en) 1997-02-13 1999-03-16 Actisystems, Inc. Aphron-containing well drilling and servicing fluids
US6123159A (en) 1997-02-13 2000-09-26 Actisystems, Inc. Aphron-containing well drilling and servicing fluids of enhanced stability
US6156708A (en) 1997-02-13 2000-12-05 Actisystems, Inc. Aphron-containing oil base fluids and method of drilling a well therewith
WO1998040413A1 (en) 1997-03-14 1998-09-17 National Starch And Chemical Investment Holding Corporation Isolation of hemicellulose from corn fiber
BR9808368A (pt) 1997-03-18 2000-05-23 Novo Nordisk As Processos para a construção de uma biblioteca de polinucleotideos homólogos recombinados, para a identificação um polipeptìdeo de interesse, e, para a produção de um polipeptìdeo de interesse.
DK0996718T3 (da) 1997-03-18 2009-04-06 Novozymes As Fremgangsmåde til konstruktion af et bibliotek ved anvendelse af DNA-shuffling
US5948653A (en) 1997-03-21 1999-09-07 Pati; Sushma Sequence alterations using homologous recombination
US6153410A (en) 1997-03-25 2000-11-28 California Institute Of Technology Recombination of polynucleotide sequences using random or defined primers
US6333181B1 (en) 1997-04-07 2001-12-25 University Of Florida Research Foundation, Inc. Ethanol production from lignocellulose
WO1998045417A1 (en) 1997-04-09 1998-10-15 Michigan State University HYPERTHERMOSTABLE α-AMYLASE
US5855243A (en) 1997-05-23 1999-01-05 Exxon Production Research Company Oil recovery method using an emulsion
US5916780A (en) 1997-06-09 1999-06-29 Iogen Corporation Pretreatment process for conversion of cellulose to fuel ethanol
AUPO758297A0 (en) 1997-06-27 1997-07-24 Rowe, James Baber Control of acidic gut syndrome
US6826296B2 (en) 1997-07-25 2004-11-30 Affymetrix, Inc. Method and system for providing a probe array chip design database
AU8908198A (en) 1997-08-15 1999-03-08 Hyseq, Inc. Methods and compositions for detection or quantification of nucleic acid species
IL134702A (en) 1997-09-11 2004-03-28 Bioventures Inc High density arrays and methods of making the same
US6465178B2 (en) 1997-09-30 2002-10-15 Surmodics, Inc. Target molecule attachment to surfaces
AU1124499A (en) 1997-10-28 1999-05-17 Maxygen, Inc. Human papillomavirus vectors
EP2386568B1 (en) 1997-10-30 2014-08-06 Novozymes A/S Alpha-amylase mutants
EP1030861A4 (en) 1997-10-31 2001-09-05 Maxygen Inc MODIFICATION OF VIRUSTROPISMIUS AND THE ECONOMIC SPECTRUM BY VIRAL GENOM MIXING
BR9813201A (pt) 1997-11-10 2000-08-29 Procter & Gamble Processo para preparação de um tablete detergente
DE69828574T2 (de) 1997-11-14 2005-10-06 Sankyo Co., Ltd. Transgenes Tier als Modell für Allergie und seine Verwendung
AU746786B2 (en) 1997-12-08 2002-05-02 California Institute Of Technology Method for creating polynucleotide and polypeptide sequences
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
WO1999041383A1 (en) 1998-02-11 1999-08-19 Maxygen, Inc. Antigen library immunization
CA2320960A1 (en) 1998-02-11 1999-08-19 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
EP1068356B8 (en) 1998-04-03 2007-01-03 Adnexus Therapeutics, Inc. Addressable protein arrays
US6156952A (en) 1998-04-09 2000-12-05 Constituent Institution Of The University Of Maryland System HIV transgenic animals and uses therefor
AU3408199A (en) 1998-05-01 1999-11-23 Novo Nordisk A/S Enhancers such as n-hydroxyacetanilide
US6048695A (en) 1998-05-04 2000-04-11 Baylor College Of Medicine Chemically modified nucleic acids and methods for coupling nucleic acids to solid support
FR2778412B1 (fr) 1998-05-05 2002-08-09 Univ Reims Champagne Ardennes Procede pour preparer une enzyme alpha-amylase thermophile et enzyme ainsi obtenue
DE19824705A1 (de) 1998-06-03 1999-12-09 Henkel Kgaa Amylase und Protease enthaltende Wasch- und Reinigungsmittel
CN1309835C (zh) 1998-06-25 2007-04-11 应用植物公司 植物可选择标记物和植物转化方法
ES2381824T3 (es) 1998-06-29 2012-05-31 Bristol-Myers Squibb Company Procedimientos para generar genotecas muy diversas
JP4335995B2 (ja) 1998-07-22 2009-09-30 昭 神谷 環境保全型粒状洗浄用組成物
FR2782323B1 (fr) 1998-08-12 2002-01-11 Proteus Procede de production in vitro de sequences polynucleotidiques recombinees, banques de sequences et sequences ainsi obtenues
GB2340755B (en) 1998-08-24 2002-09-25 Cannon Rubber Ltd Breast pump insert
US6241849B1 (en) 1998-09-17 2001-06-05 Novo Nordisk Biochem North America, Inc. Methods for deinking and decolorizing printed paper
US6277628B1 (en) 1998-10-02 2001-08-21 Incyte Genomics, Inc. Linear microarrays
US6277489B1 (en) 1998-12-04 2001-08-21 The Regents Of The University Of California Support for high performance affinity chromatography and other uses
GB2344606B (en) 1998-12-07 2003-08-13 Shell Int Research Forming a wellbore casing by expansion of a tubular member
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6368861B1 (en) 1999-01-19 2002-04-09 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
FR2788782B1 (fr) 1999-01-25 2003-01-31 Gie Agro Ind Produit multienzymatique a activites glucoamylasique, proteolytique et xylanasique et procede pour sa production par fermentation a l'etat solide de son de ble avec aspergillus niger
US6511824B1 (en) 1999-03-17 2003-01-28 Exelixis, Inc. Nucleic acids and polypeptides of invertebrate TWIK channels and methods of use
CN1940067A (zh) * 1999-03-22 2007-04-04 诺沃奇梅兹有限公司 用于在真菌细胞中表达基因的启动子
ATE408025T1 (de) 1999-03-25 2008-09-15 Serono Genetics Inst Sa Biallelische marker die im zusammenhang stehen mit medikamentenmetabolismus beteiligten genen
US6309871B1 (en) 1999-03-31 2001-10-30 Novozymes A/S Polypeptides having alkaline α-amylase activity
US6221653B1 (en) 1999-04-27 2001-04-24 Agilent Technologies, Inc. Method of performing array-based hybridization assays using thermal inkjet deposition of sample fluids
GB9915214D0 (en) 1999-06-29 1999-09-01 Bp Exploration Operating Microemulsions
US6653151B2 (en) 1999-07-30 2003-11-25 Large Scale Proteomics Corporation Dry deposition of materials for microarrays using matrix displacement
US6409841B1 (en) 1999-11-02 2002-06-25 Waste Energy Integrated Systems, Llc. Process for the production of organic products from diverse biomass sources
US20010008765A1 (en) 1999-12-06 2001-07-19 Fuji Photo Film Co., Ltd. DNA chip and reactive solid carrier
US6531644B1 (en) 2000-01-14 2003-03-11 Exelixis, Inc. Methods for identifying anti-cancer drug targets
AU2964101A (en) 2000-01-21 2001-07-31 Scripps Research Institute, The Methods and compositions to modulate expression in plants
JP4496586B2 (ja) 2000-01-24 2010-07-07 日産化学工業株式会社 キノリルアクリロニトリルの製造法及びその中間体
ES2166316B1 (es) 2000-02-24 2003-02-16 Ct Investig Energeticas Ciemat Procedimiento de produccion de etanol a partir de biomasa lignocelulosica utilizando una nueva levadura termotolerante.
EP1284286B1 (en) 2000-05-22 2011-11-09 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Alpha-isomaltosyltransferase, process for producing the same and use thereof
US6530437B2 (en) 2000-06-08 2003-03-11 Maurer Technology Incorporated Multi-gradient drilling method and system
US6423145B1 (en) 2000-08-09 2002-07-23 Midwest Research Institute Dilute acid/metal salt hydrolysis of lignocellulosics
WO2002030963A1 (en) 2000-10-12 2002-04-18 Exelixis, Inc. Human ect2 and methods of use
WO2002061102A2 (en) 2000-10-24 2002-08-08 Syngenta Participations Ag Control of gene expression in plants
US6309872B1 (en) 2000-11-01 2001-10-30 Novozymes Biotech, Inc Polypeptides having glucoamylase activity and nucleic acids encoding same
DK2169076T3 (da) * 2001-02-21 2017-02-06 Basf Enzymes Llc Enzymer med alpha-amylase-aktivitet og fremgangsmåder til anvendelse deraf
US7560126B2 (en) 2001-02-21 2009-07-14 Verenium Corporation Amylases, nucleic acids encoding them and methods for making and using them
US7659102B2 (en) 2001-02-21 2010-02-09 Verenium Corporation Amylases, nucleic acids encoding them and methods for making and using them
DE10131441A1 (de) 2001-06-29 2003-01-30 Henkel Kgaa Eine neue Gruppe von alpha-Amylasen sowie ein Verfahren zur Identifizierung und Gewinnung neuer alpha-Amylasen
AU2002319764A1 (en) * 2001-08-03 2003-02-17 Elitra Pharmaceuticals, Inc. Nucleic acids of aspergillus fumigatus encoding industrial enzymes and methods of use
KR20040029122A (ko) * 2001-08-27 2004-04-03 신젠타 파티서페이션즈 아게 자가-프로세싱 식물 및 식물 부분
US20040025922A1 (en) * 2002-08-06 2004-02-12 Jeremey Gin Mobility-aid apparatus and method using multiple height adjustments
US20050045340A1 (en) 2003-09-01 2005-03-03 Hewson James Adam Method of forming a bore
US6588501B1 (en) 2002-09-27 2003-07-08 Varco I/P, Inc. Method and apparatus to reduce hydrostatic pressure in sub sea risers using buoyant spheres
US6776979B2 (en) 2002-12-30 2004-08-17 Marvin B. Frager Periodontal treatment compound and method of use
US7373978B2 (en) 2003-02-26 2008-05-20 Exxonmobil Upstream Research Company Method for drilling and completing wells
CN111484996A (zh) * 2003-03-06 2020-08-04 巴斯夫酶有限责任公司 淀粉酶、编码它们的核酸及其制备和应用方法
US20070081157A1 (en) 2003-05-06 2007-04-12 Baker Hughes Incorporated Apparatus and method for estimating filtrate contamination in a formation fluid
US7884261B2 (en) 2004-06-30 2011-02-08 CERES,Inc. Nucleotide sequences and corresponding polypeptides conferring modulated plant growth rate and biomass in plants
US20050227930A1 (en) 2004-04-08 2005-10-13 Kgk Synergize Inc. Cholesterol lowering combination
US20060014260A1 (en) 2004-05-07 2006-01-19 Zhiliang Fan Lower cellulase requirements for biomass cellulose hydrolysis and fermentation
GB2431678B (en) 2004-06-17 2009-04-22 Exxonmobil Upstream Res Co Variable density drilling mud
ES2370768T3 (es) * 2004-11-30 2011-12-22 Genencor International, Inc. Glucoamilasa de trichoderma reesei y homólogos de la misma.
EP1838522A4 (en) 2004-12-30 2011-03-09 Sun Drilling Products Corp NANOCOMPOSITE THERMOSHELL PARTICLES, PROCESS FOR PRODUCING THE SAME, AND USE IN OIL AND NATURAL GAS DRILLING APPLICATIONS
US7350576B2 (en) 2005-08-17 2008-04-01 Halliburton Energy Services, Inc. Methods of sealing subterranean formations using rapid setting plugging compositions
US7425827B2 (en) 2005-10-03 2008-09-16 Baker Hughes Incorporated Method and apparatus for formation evaluation and borehole size determination
US20070084638A1 (en) 2005-10-19 2007-04-19 Clyde Bohnsack Drilling fluid flow facilitation
JP6199014B2 (ja) 2012-07-26 2017-09-20 株式会社ザクティ レンズユニット及びこれを具えた撮像装置
EP3011302B1 (en) 2013-06-21 2019-11-27 Bio-Rad Laboratories, Inc. Microfluidic system with fluid pickups

Also Published As

Publication number Publication date
EP3540053B1 (en) 2021-06-02
EP2069490B1 (en) 2014-12-03
PL2069490T5 (pl) 2018-09-28
US8343747B2 (en) 2013-01-01
EP2069490B2 (en) 2018-02-21
DK2069490T4 (da) 2018-04-23
AU2007336732A1 (en) 2008-07-03
US20130143295A1 (en) 2013-06-06
WO2008080093A2 (en) 2008-07-03
ES2734114T3 (es) 2019-12-04
EP2069490A4 (en) 2009-10-28
CA2673525C (en) 2017-12-05
ES2531167T5 (es) 2018-05-21
EP3540053A1 (en) 2019-09-18
DK2069490T3 (da) 2015-02-16
US20110039308A1 (en) 2011-02-17
US20190032039A1 (en) 2019-01-31
US10100299B2 (en) 2018-10-16
US10883098B2 (en) 2021-01-05
EP2479267A1 (en) 2012-07-25
CA2673525A1 (en) 2008-07-03
CA2982640A1 (en) 2008-07-03
EP2479267B1 (en) 2016-12-21
US11739312B2 (en) 2023-08-29
HUE027892T2 (en) 2016-10-28
DK2479267T3 (da) 2017-03-27
EP3101128B1 (en) 2019-04-10
DK3101128T3 (da) 2019-07-08
PL3101128T3 (pl) 2019-09-30
CN101646767A (zh) 2010-02-10
EP3101128A1 (en) 2016-12-07
PL2479267T3 (pl) 2017-06-30
EP2069490A2 (en) 2009-06-17
CN101646767B (zh) 2013-05-29
BRPI0719449A2 (pt) 2017-06-20
PL2069490T3 (pl) 2015-06-30
ES2620288T3 (es) 2017-06-28
HUE033455T2 (en) 2017-12-28
AU2007336732B2 (en) 2013-05-02
ES2575912T3 (es) 2016-07-04
EP2479266A1 (en) 2012-07-25
ES2531167T3 (es) 2015-03-11
WO2008080093A3 (en) 2008-11-06
MX2009006782A (es) 2009-09-21
PL2479266T3 (pl) 2016-09-30
EP2479266B1 (en) 2016-03-09
US20210198652A1 (en) 2021-07-01

Similar Documents

Publication Publication Date Title
US11739312B2 (en) Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them
US20190376052A1 (en) Glucanases, nucleic acids encoding them and methods for making and using them
AU2013203257B2 (en) Glucanases, nucleic acids encoding them, and methods for making and using them
AU2013203257B8 (en) Glucanases, nucleic acids encoding them, and methods for making and using them