DK2909225T3 - Fremgangsmåde til oprensning af abirateron-acetat - Google Patents
Fremgangsmåde til oprensning af abirateron-acetatInfo
- Publication number
- DK2909225T3 DK2909225T3 DK13789206.3T DK13789206T DK2909225T3 DK 2909225 T3 DK2909225 T3 DK 2909225T3 DK 13789206 T DK13789206 T DK 13789206T DK 2909225 T3 DK2909225 T3 DK 2909225T3
- Authority
- DK
- Denmark
- Prior art keywords
- abiraterone acetate
- purifying
- purifying abiraterone
- acetate
- abiraterone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Epoxy Compounds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT001788A ITMI20121788A1 (it) | 2012-10-22 | 2012-10-22 | Procedimento per la purificazione di abiraterone acetato |
| PCT/EP2013/071930 WO2014064032A1 (en) | 2012-10-22 | 2013-10-21 | Process for the purification of abiraterone acetate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2909225T3 true DK2909225T3 (da) | 2017-01-02 |
Family
ID=47425221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13789206.3T DK2909225T3 (da) | 2012-10-22 | 2013-10-21 | Fremgangsmåde til oprensning af abirateron-acetat |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9340571B2 (da) |
| EP (1) | EP2909225B1 (da) |
| JP (1) | JP2015535223A (da) |
| KR (1) | KR20150079614A (da) |
| AU (1) | AU2013336781A1 (da) |
| BR (1) | BR112015008855A2 (da) |
| CA (1) | CA2888826A1 (da) |
| DK (1) | DK2909225T3 (da) |
| ES (1) | ES2596245T3 (da) |
| IL (1) | IL238386A (da) |
| IT (1) | ITMI20121788A1 (da) |
| WO (1) | WO2014064032A1 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014071983A1 (en) * | 2012-11-09 | 2014-05-15 | Synthon Bv | Process for making the 17-triflate intermediate of abiraterone-3-acetate |
| CZ2014475A3 (cs) * | 2014-07-09 | 2016-01-20 | Zentiva, K.S. | Způsob přípravy Abirateron acetátu o vysoké čistotě aplikovatelný v průmyslovém měřítku |
| CN104109185B (zh) * | 2014-08-06 | 2016-05-18 | 亿腾药业（泰州）有限公司 | 一种醋酸阿比特龙的制备方法 |
| CN104447934B (zh) * | 2014-12-08 | 2017-03-15 | 深圳科兴生物工程有限公司 | 一种醋酸阿比特龙的纯化方法 |
| KR102363026B1 (ko) | 2019-12-26 | 2022-02-16 | 보령제약 주식회사 | 아비라테론 아세테이트 또는 이의 약제학적으로 허용 가능한 염을 포함하는 전립선암 예방 또는 치료용 약학적 조성물 |
| CN116490165A (zh) * | 2020-09-02 | 2023-07-25 | 普洛佩拉治疗公司 | 阿比特龙前药 |
| CN112125942B (zh) * | 2020-09-28 | 2021-12-14 | 湖南新合新生物医药有限公司 | 醋酸阿比特龙及其中间体的合成方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0733395B2 (ja) * | 1987-06-19 | 1995-04-12 | 武田薬品工業株式会社 | 抗生物質ｔａｎ−９２８およびその製造法 |
| JPH05194585A (ja) * | 1991-03-13 | 1993-08-03 | Kyowa Hakko Kogyo Co Ltd | 化合物ｕｃａ１０６４−ｂ |
| JPH0576387A (ja) * | 1991-07-22 | 1993-03-30 | Snow Brand Milk Prod Co Ltd | １４α− ヒドロキシ−４− アンドロステン−３，６，１７−トリオンの新規製造方法 |
| CA2132449C (en) | 1992-03-31 | 2002-09-10 | Susan E. Barrie | 17 - substituted steroids useful in cancer treatment |
| JPH06225793A (ja) * | 1992-11-27 | 1994-08-16 | Nippon Kayaku Co Ltd | ６β，１４α−ジヒドロキシ−４−アンドロステン−３，１７−ジオンの新規製造法 |
| AU676088B2 (en) * | 1993-09-30 | 1997-02-27 | British Technology Group Limited | Synthesis of 17-(3-pyridyl) steroids |
| JPH09511902A (ja) * | 1993-12-29 | 1997-12-02 | 藤沢薬品工業株式会社 | Ｗｆ１５６０４物質 |
| JPH08269085A (ja) * | 1995-03-30 | 1996-10-15 | Sankyo Co Ltd | 新規スキャララン誘導体 |
| JPH10245393A (ja) * | 1997-02-28 | 1998-09-14 | Shiseido Co Ltd | トリテルペン類を含有する組成物 |
| JP2001322934A (ja) * | 2000-05-11 | 2001-11-20 | Saraya Kk | 抗酸化作用を有する羅漢果配糖体を含有する抗酸化組成物 |
| JP4456321B2 (ja) * | 2002-07-12 | 2010-04-28 | 株式会社ファンケル | リパーゼ阻害剤 |
| US20050143464A1 (en) * | 2003-09-22 | 2005-06-30 | Use-Techno Corporation | Insulin secretion potentiator |
| EP2428519B1 (en) | 2004-08-24 | 2015-01-21 | BTG International Limited | Composition for the preparation of 17-vinyl- triflates as intermediates |
| GB0418900D0 (en) | 2004-08-24 | 2004-09-29 | Btg Int Ltd | Novel salt forms |
| JP4813917B2 (ja) * | 2005-02-22 | 2011-11-09 | 丸善製薬株式会社 | 皮膚化粧料 |
| JP2007145782A (ja) * | 2005-11-30 | 2007-06-14 | Meiji Milk Prod Co Ltd | ニガウリ抽出物を主成分とする血糖値降下剤、および食品・医薬品組成物 |
| CN101768199B (zh) * | 2009-12-24 | 2014-03-26 | 深圳万乐药业有限公司 | 醋酸阿比特龙的多晶型物及其制备方法 |
| CN102030798B (zh) * | 2010-12-17 | 2012-10-17 | 深圳万乐药业有限公司 | 一种醋酸阿比特龙的纯化方法 |
| CN104066744B (zh) * | 2011-10-10 | 2017-03-22 | 扎克系统公司 | 用于制备17‑取代的甾体的方法 |
-
2012
- 2012-10-22 IT IT001788A patent/ITMI20121788A1/it unknown
-
2013
- 2013-10-21 EP EP13789206.3A patent/EP2909225B1/en active Active
- 2013-10-21 CA CA2888826A patent/CA2888826A1/en not_active Abandoned
- 2013-10-21 KR KR1020157010167A patent/KR20150079614A/ko not_active Withdrawn
- 2013-10-21 BR BR112015008855A patent/BR112015008855A2/pt not_active IP Right Cessation
- 2013-10-21 AU AU2013336781A patent/AU2013336781A1/en not_active Abandoned
- 2013-10-21 DK DK13789206.3T patent/DK2909225T3/da active
- 2013-10-21 ES ES13789206.3T patent/ES2596245T3/es active Active
- 2013-10-21 US US14/436,527 patent/US9340571B2/en active Active
- 2013-10-21 JP JP2015537288A patent/JP2015535223A/ja active Pending
- 2013-10-21 WO PCT/EP2013/071930 patent/WO2014064032A1/en not_active Ceased
-
2015
- 2015-04-20 IL IL238386A patent/IL238386A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20160052958A1 (en) | 2016-02-25 |
| US9340571B2 (en) | 2016-05-17 |
| EP2909225B1 (en) | 2016-09-14 |
| WO2014064032A1 (en) | 2014-05-01 |
| CA2888826A1 (en) | 2014-05-01 |
| AU2013336781A1 (en) | 2015-05-07 |
| BR112015008855A2 (pt) | 2017-07-04 |
| IL238386A0 (en) | 2015-06-30 |
| ES2596245T3 (es) | 2017-01-05 |
| EP2909225A1 (en) | 2015-08-26 |
| IL238386A (en) | 2017-07-31 |
| KR20150079614A (ko) | 2015-07-08 |
| JP2015535223A (ja) | 2015-12-10 |
| ITMI20121788A1 (it) | 2014-04-23 |
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