DK3688189T3 - Fejldetektering under hybridisering af dobbeltstrenget målnukleinsyre - Google Patents
Fejldetektering under hybridisering af dobbeltstrenget målnukleinsyre Download PDFInfo
- Publication number
- DK3688189T3 DK3688189T3 DK18782786.0T DK18782786T DK3688189T3 DK 3688189 T3 DK3688189 T3 DK 3688189T3 DK 18782786 T DK18782786 T DK 18782786T DK 3688189 T3 DK3688189 T3 DK 3688189T3
- Authority
- DK
- Denmark
- Prior art keywords
- nucleic acid
- target nucleic
- error detection
- acid hybridization
- stranded target
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1031—Mutagenizing nucleic acids mutagenesis by gene assembly, e.g. assembly by oligonucleotide extension PCR
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/107—Temperature of melting, i.e. Tm
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2545/00—Reactions characterised by their quantitative nature
- C12Q2545/10—Reactions characterised by their quantitative nature the purpose being quantitative analysis
- C12Q2545/107—Reactions characterised by their quantitative nature the purpose being quantitative analysis with a competitive internal standard/control
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Computational Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1715852.8A GB2566986A (en) | 2017-09-29 | 2017-09-29 | Error detection during hybridisation of target double-stranded nucleic acid |
| GB1721441.2A GB2568974A (en) | 2017-09-29 | 2017-12-20 | Error detection during hybridisation of target double-stranded nucleic acid |
| PCT/GB2018/052753 WO2019064006A1 (en) | 2017-09-29 | 2018-09-27 | ERROR DETECTION DURING TARGET DOUBLE-BIT NUCLEIC ACID HYBRIDIZATION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3688189T3 true DK3688189T3 (da) | 2022-07-11 |
Family
ID=60270222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18782786.0T DK3688189T3 (da) | 2017-09-29 | 2018-09-27 | Fejldetektering under hybridisering af dobbeltstrenget målnukleinsyre |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11629377B2 (da) |
| EP (1) | EP3688189B1 (da) |
| JP (1) | JP7201674B2 (da) |
| KR (1) | KR102888533B1 (da) |
| CN (1) | CN111164220B (da) |
| AU (1) | AU2018343116B2 (da) |
| CA (1) | CA3077106A1 (da) |
| DK (1) | DK3688189T3 (da) |
| ES (1) | ES2920355T3 (da) |
| GB (2) | GB2566986A (da) |
| IL (1) | IL273298B2 (da) |
| SG (1) | SG11202002188YA (da) |
| WO (1) | WO2019064006A1 (da) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111143235A (zh) * | 2018-11-06 | 2020-05-12 | 爱思开海力士有限公司 | 多内核存储器系统中的逻辑地址分配 |
| WO2022261366A1 (en) * | 2021-06-09 | 2022-12-15 | Avery Digital Data, Inc. | Electronic devices for polymer synthesis and assembly |
| GB2621385A (en) * | 2022-08-11 | 2024-02-14 | Evonetix Ltd | Reaction duration control for reaction performed on biomolecule samples |
| GB202300626D0 (en) | 2023-01-16 | 2023-03-01 | Evonetix Ltd | Hybridisation detection |
Family Cites Families (69)
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| GB8818020D0 (en) * | 1988-07-28 | 1988-09-01 | Ici Plc | Method for amplification of nucleotide sequences |
| ATE143696T1 (de) | 1989-02-28 | 1996-10-15 | Canon Kk | Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung |
| US6099803A (en) | 1994-07-07 | 2000-08-08 | Nanogen, Inc. | Advanced active electronic devices for molecular biological analysis and diagnostics |
| US6495318B2 (en) | 1996-06-17 | 2002-12-17 | Vectorobjects, Llc | Method and kits for preparing multicomponent nucleic acid constructs |
| IL120337A0 (en) | 1997-02-27 | 1997-06-10 | Gesher Israel Advanced Biotecs | Method for joining DNA fragments |
| IL120339A0 (en) | 1997-02-27 | 1997-06-10 | Gesher Israel Advanced Biotecs | Improved DNA assembly method |
| US6410220B1 (en) | 1997-02-28 | 2002-06-25 | Nature Technology Corp | Self-assembling genes, vectors and uses thereof |
| WO1999002725A1 (en) | 1997-07-11 | 1999-01-21 | Brax Group Limited | Categorising nucleic acid |
| PT1015576E (pt) | 1997-09-16 | 2005-09-30 | Egea Biosciences Llc | Metodo para a sintese quimica completa e montagem de genes e de genomas |
| CA2360011A1 (en) | 1999-01-05 | 2000-07-13 | Trustees Of Boston University | Ordered gene assembly |
| WO2000049142A1 (de) | 1999-02-19 | 2000-08-24 | Febit Ferrarius Biotechnology Gmbh | Verfahren zur herstellung von polymeren |
| GB9908814D0 (en) | 1999-04-16 | 1999-06-09 | Celltech Therapeutics Ltd | Process |
| DE19925862A1 (de) | 1999-06-07 | 2000-12-14 | Diavir Gmbh | Verfahren zur Synthese von DNA-Fragmenten |
| US6184000B1 (en) | 1999-07-23 | 2001-02-06 | The United States Of America As Represented By The Secretary Of Agriculture | System for the sequential, directional cloning of multiple DNA sequences |
| WO2001081568A1 (en) | 2000-04-21 | 2001-11-01 | Genencor International, Inc. | Non-pcr based recombination of nucleic acids |
| WO2001083826A2 (en) | 2000-05-03 | 2001-11-08 | Massachusetts Institute Of Technology | Methods and reagents for assembling molecules on solid supports |
| US6685812B2 (en) | 2001-01-09 | 2004-02-03 | The Regents Of The University Of California | Movement of particles using sequentially activated dielectrophoretic particle trapping |
| EP1385950B1 (en) | 2001-01-19 | 2008-07-02 | Centocor, Inc. | Computer-directed assembly of a polynucleotide encoding a target polypeptide |
| AU2002314997A1 (en) | 2001-06-05 | 2002-12-16 | Gorilla Genomics, Inc. | Methods for low background cloning of dna using long oligonucleotides |
| AU2002353997A1 (en) * | 2001-11-01 | 2003-05-12 | Rensselaer Polytechnic Institute | In vitro metabolic engineering on microscale devices |
| EP1314783B1 (de) | 2001-11-22 | 2008-11-19 | Sloning BioTechnology GmbH | Nukleinsäure-Linker und deren Verwendung in der Gensynthese |
| US7563600B2 (en) | 2002-09-12 | 2009-07-21 | Combimatrix Corporation | Microarray synthesis and assembly of gene-length polynucleotides |
| EP1552001A4 (en) | 2002-09-19 | 2006-01-04 | Applera Corp | METHODS AND COMPOSITIONS FOR TARGET DETECTION |
| ES2310197T3 (es) | 2002-10-18 | 2009-01-01 | Sloning Biotechnology Gmbh | Metodo para la preparacion de moleculas de acido nucleico. |
| US7090979B2 (en) | 2002-11-22 | 2006-08-15 | The Regents Of The University Of California | Derivatized versions of ligase enzymes for constructing DNA sequences |
| US7879580B2 (en) | 2002-12-10 | 2011-02-01 | Massachusetts Institute Of Technology | Methods for high fidelity production of long nucleic acid molecules |
| US7932025B2 (en) * | 2002-12-10 | 2011-04-26 | Massachusetts Institute Of Technology | Methods for high fidelity production of long nucleic acid molecules with error control |
| WO2004113534A1 (en) | 2003-05-22 | 2004-12-29 | University Of California | Method for producing a synthetic gene or other dna sequence |
| ES2353302T3 (es) | 2004-01-23 | 2011-03-01 | Sloning Biotechnology Gmbh | Producción enzimática de novo de moléculas de ácido nucleico. |
| AU2005222788A1 (en) | 2004-02-27 | 2005-09-29 | President And Fellows Of Harvard College | Polynucleotide synthesis |
| AU2005279931B2 (en) | 2004-08-27 | 2011-02-10 | Wisconsin Alumni Research Foundation | Method of error reduction in nucleic acid populations |
| JP2008523786A (ja) * | 2004-10-18 | 2008-07-10 | コドン デバイシズ インコーポレイテッド | 高忠実度合成ポリヌクレオチドのアセンブリ方法 |
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| US10087450B2 (en) | 2011-08-31 | 2018-10-02 | Academia Sinica | Engineered yeast for production of enzymes |
| TWI444476B (zh) | 2011-08-31 | 2014-07-11 | Academia Sinica | 將多重基因順序化及插入基因體且同時過度表現該等多重基因之方法 |
| IL236303B (en) | 2012-06-25 | 2022-07-01 | Gen9 Inc | Methods for high-throughput nucleic acid assembly and sequencing |
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| EP3375876A1 (en) | 2017-03-13 | 2018-09-19 | Evonetix Ltd | Method for producing double stranded polynucleotides based on oligonucleotides with selected and different melting temperatures |
-
2017
- 2017-09-29 GB GB1715852.8A patent/GB2566986A/en not_active Withdrawn
- 2017-12-20 GB GB1721441.2A patent/GB2568974A/en not_active Withdrawn
-
2018
- 2018-09-27 DK DK18782786.0T patent/DK3688189T3/da active
- 2018-09-27 JP JP2020517439A patent/JP7201674B2/ja active Active
- 2018-09-27 CN CN201880063180.4A patent/CN111164220B/zh active Active
- 2018-09-27 EP EP18782786.0A patent/EP3688189B1/en active Active
- 2018-09-27 US US16/647,939 patent/US11629377B2/en active Active
- 2018-09-27 AU AU2018343116A patent/AU2018343116B2/en active Active
- 2018-09-27 KR KR1020207011334A patent/KR102888533B1/ko active Active
- 2018-09-27 IL IL273298A patent/IL273298B2/en unknown
- 2018-09-27 WO PCT/GB2018/052753 patent/WO2019064006A1/en not_active Ceased
- 2018-09-27 CA CA3077106A patent/CA3077106A1/en active Pending
- 2018-09-27 ES ES18782786T patent/ES2920355T3/es active Active
- 2018-09-27 SG SG11202002188YA patent/SG11202002188YA/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20200248254A1 (en) | 2020-08-06 |
| AU2018343116A1 (en) | 2020-03-26 |
| SG11202002188YA (en) | 2020-04-29 |
| WO2019064006A1 (en) | 2019-04-04 |
| JP2020537511A (ja) | 2020-12-24 |
| US11629377B2 (en) | 2023-04-18 |
| GB2568974A (en) | 2019-06-05 |
| GB201715852D0 (en) | 2017-11-15 |
| ES2920355T3 (es) | 2022-08-03 |
| EP3688189B1 (en) | 2022-05-04 |
| GB2566986A (en) | 2019-04-03 |
| JP7201674B2 (ja) | 2023-01-10 |
| IL273298B2 (en) | 2024-10-01 |
| AU2018343116B2 (en) | 2024-07-04 |
| IL273298B1 (en) | 2024-06-01 |
| GB201721441D0 (en) | 2018-01-31 |
| EP3688189A1 (en) | 2020-08-05 |
| KR102888533B1 (ko) | 2025-11-21 |
| CN111164220B (zh) | 2023-12-12 |
| IL273298A (en) | 2020-04-30 |
| CA3077106A1 (en) | 2019-04-04 |
| CN111164220A (zh) | 2020-05-15 |
| KR20200058461A (ko) | 2020-05-27 |
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| DK3688189T3 (da) | Fejldetektering under hybridisering af dobbeltstrenget målnukleinsyre |