DK431289D0 - Humant rhinovirus-receptorprotein - Google Patents

Humant rhinovirus-receptorprotein

Info

Publication number
DK431289D0
DK431289D0 DK431289A DK431289A DK431289D0 DK 431289 D0 DK431289 D0 DK 431289D0 DK 431289 A DK431289 A DK 431289A DK 431289 A DK431289 A DK 431289A DK 431289 D0 DK431289 D0 DK 431289D0
Authority
DK
Denmark
Prior art keywords
receptor
hrv
detergent
receptor protein
humant
Prior art date
Application number
DK431289A
Other languages
English (en)
Other versions
DK174095B1 (da
DK431289A (da
Inventor
Jeffrey Greve
Alan Mcclelland
Gary Davis
Original Assignee
Molecular Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Therapeutics Inc filed Critical Molecular Therapeutics Inc
Publication of DK431289D0 publication Critical patent/DK431289D0/da
Publication of DK431289A publication Critical patent/DK431289A/da
Application granted granted Critical
Publication of DK174095B1 publication Critical patent/DK174095B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK198904312A 1988-09-01 1989-08-31 Anvendelse af et humant rhinovirus (HRV)-hovedreceptorpræparat til fremstilling af et lægemiddel til inhibering af initieringen eller spredningen af rhino-virusinfektion DK174095B1 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US23957188A 1988-09-01 1988-09-01
US23957188 1988-09-01
US26242888A 1988-10-25 1988-10-25
US26242888 1988-10-25
US39066289A 1989-08-10 1989-08-10
US39066289 1989-08-10

Publications (3)

Publication Number Publication Date
DK431289D0 true DK431289D0 (da) 1989-08-31
DK431289A DK431289A (da) 1990-03-02
DK174095B1 DK174095B1 (da) 2002-06-10

Family

ID=27399251

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198904312A DK174095B1 (da) 1988-09-01 1989-08-31 Anvendelse af et humant rhinovirus (HRV)-hovedreceptorpræparat til fremstilling af et lægemiddel til inhibering af initieringen eller spredningen af rhino-virusinfektion

Country Status (15)

Country Link
US (1) US7132395B1 (da)
EP (1) EP0362531B1 (da)
JP (1) JP3253064B2 (da)
AT (1) ATE186552T1 (da)
AU (1) AU637324B2 (da)
CA (1) CA1339193C (da)
DE (1) DE68929096T2 (da)
DK (1) DK174095B1 (da)
ES (1) ES2141076T3 (da)
FI (1) FI894065L (da)
GR (1) GR3032456T3 (da)
IL (1) IL91454A (da)
NO (1) NO893373L (da)
NZ (1) NZ230474A (da)
PT (1) PT91570B (da)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006592A1 (en) * 1987-02-26 1988-09-07 Dana-Farber Cancer Institute, Inc. Cloning of lfa-1
US5585264A (en) * 1988-07-15 1996-12-17 University Of Saskatchewan Nucleotide sequences encoding recombinant bovine herpesvirus type-1 GI, GIII and GIV polypeptides
US5151267A (en) * 1988-07-15 1992-09-29 University Of Saskatchewan Bovine herpesvirus type 1 polypeptides and vaccines
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
EP0362531B1 (en) 1988-09-01 1999-11-10 Bayer Corporation A human rhinovirus receptor protein that inhibits virus infectivity
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
NO900155L (no) * 1989-01-24 1990-07-25 Molecular Therapeutics Inc Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1.
EP0462184A4 (en) * 1989-03-09 1992-01-08 Dana Farber Cancer Institute Method of treating viral infections using lfa-1
DK0745852T3 (da) * 1989-03-16 2002-10-14 Blood Res Center Anvendelse af funktionelle derivater af intercellulær adhæsion-molekylet ICAM-1 i antiviral terapi
WO1991018010A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
ATE184049T1 (de) * 1990-07-20 1999-09-15 Bayer Ag Multimere formen des menschlichen rhinovirus- rezeptorproteins
US5686582A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US5288854A (en) * 1990-11-28 1994-02-22 Center For Blood Research, Inc. Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1
US5629162A (en) * 1991-06-11 1997-05-13 The Center For Blood Research Method of identifying agents which modulate ICAM-3 binding to LFA-1
US5811517A (en) * 1992-01-27 1998-09-22 Icos Corporation ICAM-related protein variants
EP0578819A4 (en) * 1992-01-27 1994-10-12 Icos Corp Icam-related protein.
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
AU710965B2 (en) * 1992-06-22 1999-09-30 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
WO1994011400A1 (en) * 1992-11-18 1994-05-26 Helsinki University Licensing Ltd. Oy Peptides from human icam-2 and from human icam-1 and their analogs for use in therapy and diagnosis
GB9414966D0 (en) * 1994-07-26 1994-09-14 Danbiosyst Uk Pharmaceutical compositions for the nasal administration of antiviral agents
US5879712A (en) * 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced
US6365343B1 (en) * 1996-03-06 2002-04-02 Boehringer Ingelheim Pharmaceuticals, Inc. Intercellular adhesion molecule powder formulation
US6391452B1 (en) 1997-07-18 2002-05-21 Bayer Corporation Compositions for nasal drug delivery, methods of making same, and methods of removing residual solvent from pharmaceutical preparations
AU2004287875B2 (en) 2003-11-05 2011-06-02 Bausch + Lomb Ireland Limited Modulators of cellular adhesion
SI1881823T1 (sl) 2005-05-17 2015-04-30 Sarcode Bioscience Inc. Sestavki in postopki za zdravljenje bolezni oäśesa
CA2702984C (en) 2007-10-19 2017-04-11 Sarcode Corporation Compositions and methods for treatment of diabetic retinopathy
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US8378105B2 (en) 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
EP2877465A4 (en) 2012-07-25 2016-05-11 Sarcode Bioscience Inc LFA-1 HEMMER AND POLYMORPH THEREOF
EP3419629A4 (en) 2016-02-25 2019-10-30 Applied Biological Laboratories, Inc. COMPOSITIONS AND PROCEDURES FOR PROTECTION AGAINST AIRBORNE PATHOGENES AND IRRITATES
US12447166B2 (en) 2016-02-25 2025-10-21 Applied Biological Laboratories, Inc. Compositions and methods for protecting against airborne pathogens and irritants

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4209526A (en) 1977-08-05 1980-06-24 Sterling Drug Inc. Antiviral arylenedioxyalkyl substituted pyrazoles
US4261928A (en) 1977-08-05 1981-04-14 Sterling Drug Inc. 2-Benzoyl-8-(2-chloro-4-methoxyphenoxy)-1-phenyl-1-octanone
US4171365A (en) 1977-08-05 1979-10-16 Sterling Drug Inc. Antiviral aryloxyalkylpyrazoles
FR2432170A1 (fr) 1978-06-12 1980-02-22 Corning Glass Works Procede de mesure de recepteurs d'antigene sur des membranes de cellules
US4232161A (en) 1979-10-24 1980-11-04 Sterling Drug Inc. 4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-(2-pyridinyl)-1H-pyrazole
US4234725A (en) 1979-10-24 1980-11-18 Sterling Drug Inc. 4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-[4-(4-morpholinyl)-1-oxobutyl]-1H-pyrazole
US5179017A (en) 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4427653A (en) 1981-01-26 1984-01-24 President And Fellows Of Harvard College Method of making monoclonal antibodies
US4372976A (en) 1981-08-07 1983-02-08 Sterling Drug Inc. Novel aryl-aliphatic ketone and its use as an antiviral agent
US4451476A (en) 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
US4843087A (en) 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
EP0169146A3 (en) * 1984-07-20 1988-07-20 Merck & Co. Inc. Monoclonal antibodies directed against the cellular receptor of human rhinovirus
JPS6181798A (ja) 1984-07-23 1986-04-25 ベクトン・デイツキンソン・アンド・カンパニ− 細胞リセプタ−の回収
DE3505148A1 (de) 1985-02-15 1986-10-30 Boehringer Ingelheim International GmbH, 6507 Ingelheim Polypeptide des rhinovirusstammes hrv2 sowie die hierfuer codierenden dna-molekuele
CA1280753C (en) 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans
EP0227604A3 (en) 1985-12-23 1989-01-18 Sandoz Ag Use of oligopeptides in the treatment of viral infections
EP0261403A3 (de) 1986-08-23 1988-04-13 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Polypeptide des Rhinovirusstammes HRV89 sowie die hierfür codierenden DNA-Moleküle
WO1988006592A1 (en) 1987-02-26 1988-09-07 Dana-Farber Cancer Institute, Inc. Cloning of lfa-1
JPS63276494A (ja) 1987-02-26 1988-11-14 ダナーファーバー・キャンサー・インスチチュート・インコーポレーテッド Ｌｆａ−３の精製法
US5603932A (en) 1987-04-14 1997-02-18 Boehringer Ingelheim International Gmbh Receptor of the minor human rhinovirus receptor group
US5304636A (en) 1987-04-14 1994-04-19 Boehringer Ingelheim International Gmbh Receptor for the human rhinovirus minor group
DE3712678A1 (de) 1987-04-14 1988-10-27 Boehringer Ingelheim Int Rezeptor der kleinen rhinovirus rezeptor gruppe
ATE128727T1 (de) 1987-05-04 1995-10-15 Dana Farber Cancer Inst Inc Interzellulare adhäsions-moleküle und deren bindungsliganden.
US5831036A (en) 1987-05-04 1998-11-03 Dana Farber Cancer Institute Soluble fragments of human intercellular adhesion molecule-1
AU629189B2 (en) 1987-05-04 1992-10-01 Dana-Farber Cancer Institute Intercellular adhesion molecules and their binding ligands
US5284931A (en) 1987-05-04 1994-02-08 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
US4956281A (en) 1987-06-03 1990-09-11 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing lymphocyte function associated antigen-3
US5109123A (en) 1988-06-14 1992-04-28 Dana Farber Cancer Institute Alteration of ability of soluble CD4 fragments to bind HIV
ATE114972T1 (de) 1987-11-02 1994-12-15 Baylor College Medicine Verwendung von icam-1 oder ihre funktionelle derivate zur behandlung unspezifischer entzündungen.
US5081228A (en) 1988-02-25 1992-01-14 Immunex Corporation Interleukin-1 receptors
CA1341055C (en) * 1987-12-08 2000-07-18 Alan Mcclelland Transfectant cell lines which express the major human rhinovirus receptor
US5395929A (en) 1987-12-15 1995-03-07 Dana Farber Cancer Institute Isolated nucleic acid encoding the alpha subunit of the human leukocyte adhesion receptor
AU638210B2 (en) 1988-05-04 1993-06-24 Dana-Farber Cancer Institute, Inc. Protein micelles
ATE123810T1 (de) 1988-08-23 1995-06-15 Dana Farber Cancer Inst Inc Alpha-subeinheit des lfa-1-leukocyt-adhäsions- rezeptors.
US6143298A (en) 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6514936B1 (en) * 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
US6051231A (en) 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
EP0362531B1 (en) 1988-09-01 1999-11-10 Bayer Corporation A human rhinovirus receptor protein that inhibits virus infectivity
ZA896668B (en) 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
ES2077572T3 (es) 1988-09-28 1995-12-01 Dana Farber Cancer Inst Inc Moleculas de adhesion intercelular, y sus ligandos de fijacion.
KR900701846A (ko) 1988-09-28 1990-12-04 원본미기재 세포간 점착분자 및 이의 결합 리간드
US5372933A (en) 1988-10-03 1994-12-13 The Scripps Research Institute Polypeptides that mimic receptor-induced binding sites, and methods of using same
CA2008368C (en) 1989-01-24 2003-04-08 Jeffrey Greve Soluble molecule related to but distinct from icam-1
PT92900A (pt) 1989-01-24 1990-07-31 Sistema de vectores de expressao para a producao de anticorpos monoclonais quimericos
NO900155L (no) 1989-01-24 1990-07-25 Molecular Therapeutics Inc Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1.
US5235049A (en) 1989-01-24 1993-08-10 Molecular Therapeutics, Inc. Nucleic acid sequences encoding a soluble molecule (SICAM-1) related to but distinct from ICAM-1
JPH04505613A (ja) 1989-03-09 1992-10-01 ダナ・ファーバー・キャンサー・インスティチュート 白血球付着レセプター
ES2035668T3 (es) 1989-03-09 1993-04-16 Boehringer Ingelheim Pharmaceuticals Inc. Uso de moleculas de adherencia intercelular y sus ligandos de union en el tratamiento del asma.
EP0462184A4 (en) 1989-03-09 1992-01-08 Dana Farber Cancer Institute Method of treating viral infections using lfa-1
DK0745852T3 (da) * 1989-03-16 2002-10-14 Blood Res Center Anvendelse af funktionelle derivater af intercellulær adhæsion-molekylet ICAM-1 i antiviral terapi
HU217792B (hu) 1989-03-16 2000-04-28 Dana Farber Cancer Institute Eljárás intercelluláris adhéziós molekula (ICAM-1) oldható származékai és ezeket tartalmazó gyógyszerkészítmények előállítására
AU5553290A (en) 1989-04-28 1990-11-29 Baylor College Of Medicine Dissemination of hiv-1 infected cells
US5324510A (en) 1989-09-01 1994-06-28 Boehringer Ingelheim Pharmaceuticals, Inc. Use of antibodies to intercellular adhesion molecule-1 (ICAM-1) in the treatment of asthma
GB9009548D0 (en) 1990-04-27 1990-06-20 Celltech Ltd Chimeric antibody and method
GB9009549D0 (en) 1990-04-27 1990-06-20 Celltech Ltd Recombinant antibody and method
WO1991018010A1 (en) 1990-05-15 1991-11-28 Swinburne Limited Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
WO1991018011A1 (en) 1990-05-15 1991-11-28 Swinburne Limited Inhibition of cell adhesion using intercellular adhesion molecule-1-like peptides and/or analogues thereof
US5349053A (en) 1990-06-01 1994-09-20 Protein Design Labs, Inc. Chimeric ligand/immunoglobulin molecules and their uses
EP0459577A3 (en) 1990-06-01 1992-08-05 Merck & Co. Inc. Microbially expressed portions of a monoclonal antibody block rhinovirus attachment to cell receptors
AU658370B2 (en) 1990-07-13 1995-04-13 General Hospital Corporation, The CD53 cell surface antigen and use thereof
US5686582A (en) 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
ATE184049T1 (de) 1990-07-20 1999-09-15 Bayer Ag Multimere formen des menschlichen rhinovirus- rezeptorproteins
US6107461A (en) 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US5686581A (en) 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
JPH06500555A (ja) 1990-08-27 1994-01-20 カイロン　コーポレイション 病気の処置のためのペプチドの薬物
AU8765391A (en) 1990-10-03 1992-04-28 Boehringer Ingelheim Pharmaceuticals, Inc. Method for treating inflammation using anti-idiotypic antibodies
US5288854A (en) 1990-11-28 1994-02-22 Center For Blood Research, Inc. Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1
ATE145428T1 (de) 1990-12-14 1996-12-15 Cell Genesys Inc Chimärische ketten zur transduktion von rezeptorverbundenen signalwegen
US5709859A (en) 1991-01-24 1998-01-20 Bristol-Myers Squibb Company Mixed specificity fusion proteins
EP0510483A1 (en) 1991-04-22 1992-10-28 Boehringer Ingelheim Pharmaceuticals Inc. Method for the detection of viruses
US5223396A (en) 1991-05-03 1993-06-29 Boehringer Ingelheim Pharmaceuticals, Inc. Method for detecting organ transplant rejection
US5240694A (en) 1991-09-23 1993-08-31 University Of Virginia Combined antiviral and antimediator treatment of common colds
WO1993006842A1 (en) 1991-10-02 1993-04-15 Boehringer Ingelheim Pharmaceuticals, Inc. Use of intercellular adhesion molecules, and their binding ligands in the treatment of asthma
AU2797892A (en) 1991-10-03 1993-05-03 Center For Blood Research, The (plasmodium falciparum)-infected erythrocytes binding to icam-1 and cd36
AU2777092A (en) 1991-10-04 1993-05-03 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The Treatment of ocular inflammation by blockage of cell adhesion molecules
US5861151A (en) 1991-12-20 1999-01-19 Bristol-Myers Squibb Co Soluble fusion molecules with binding specificity for cell adhesion molecules
US5525487A (en) 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
EP0578819A4 (en) 1992-01-27 1994-10-12 Icos Corp Icam-related protein.
US5532127A (en) 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
CA2092645A1 (en) 1992-03-13 1993-09-14 Maureen K. Highkin Production of recombinant proteins using herpes virus promoters and vp16 transactivators
CA2116109A1 (en) 1992-06-22 1994-01-06 Jeffrey M. Greve Multimeric forms of human rhinovirus receptor protein
WO1994001553A1 (de) 1992-07-08 1994-01-20 Boehringer Ingelheim International Gmbh Rezeptorderivate mit bindungsstellen für humane rhinoviren
US5580969A (en) 1992-07-24 1996-12-03 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ICAM-I RNA
WO1994011400A1 (en) 1992-11-18 1994-05-26 Helsinki University Licensing Ltd. Oy Peptides from human icam-2 and from human icam-1 and their analogs for use in therapy and diagnosis
CA2187360A1 (en) 1994-04-12 1995-10-19 Craig D. Wegner Use of agents which block intercellular adhesion molecule/receptor interaction in the treatment of respiratory viral infection
EP0762886A4 (en) 1994-04-19 1999-03-31 Univ Kansas ICAM-1 / LFA-1 SHORT CHAIN PEPTIDES AND METHODS FOR USE THEREOF
GB9414966D0 (en) 1994-07-26 1994-09-14 Danbiosyst Uk Pharmaceutical compositions for the nasal administration of antiviral agents
JPH10504828A (ja) 1994-08-30 1998-05-12 ハイアル ファーマスティカル コーポレイション 細胞活性調整のためのヒアルロン酸およびその誘導体
US5733540A (en) 1995-03-08 1998-03-31 Lee; Peter Poon-Hang Protection from viral infection via colonization of mucosal membranes with genetically modified bacteria
US5695760A (en) 1995-04-24 1997-12-09 Boehringer Inglehiem Pharmaceuticals, Inc. Modified anti-ICAM-1 antibodies and their use in the treatment of inflammation
US5879712A (en) 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced
ES2222775B1 (es) 2002-01-31 2006-12-16 Laboratorios Indas, S.A. Procedimiento para la deteccion de una predisposicion a una enfermedad cardiovascular.
AUPS161102A0 (en) 2002-04-08 2002-05-16 Industrial Engineering Technology Pty Ltd Improved gas burner

Also Published As

Publication number Publication date
PT91570B (pt) 1995-05-31
AU4027189A (en) 1990-03-08
NO893373L (no) 1990-03-02
NO893373D0 (no) 1989-08-22
GR3032456T3 (en) 2000-05-31
EP0362531B1 (en) 1999-11-10
EP0362531A1 (en) 1990-04-11
ATE186552T1 (de) 1999-11-15
ES2141076T3 (es) 2000-03-16
FI894065A7 (fi) 1990-03-02
NZ230474A (en) 1993-03-26
US7132395B1 (en) 2006-11-07
PT91570A (pt) 1990-03-30
DE68929096T2 (de) 2000-05-11
JP3253064B2 (ja) 2002-02-04
IL91454A (en) 1995-08-31
FI894065A0 (fi) 1989-08-30
AU637324B2 (en) 1993-05-27
DK174095B1 (da) 2002-06-10
IL91454A0 (en) 1990-04-29
DK431289A (da) 1990-03-02
FI894065L (fi) 1990-03-02
DE68929096D1 (de) 1999-12-16
CA1339193C (en) 1997-08-05
JPH02238892A (ja) 1990-09-21

Similar Documents

Publication Publication Date Title
DK431289A (da) Humant rhinovirus-receptorprotein
RU97115895A (ru) Переключение клеточного иммунитета, осуществляемое с помощью тирозин-специфических протеинкиназных химер
DE3172465D1 (en) Method for the detection of fecal hemoglobin
ATE98376T1 (de) Synthetische htlv-iii-peptid-zusammensetzungen und ihre verwendung.
NO885326L (no) Human vevfaktor-beslektede dna-segmenter, polypeptider ogantistoffer.
ES2050114T3 (es) Anticuerpos monoclonales humanos para el virus asociado a la linfoadenopatia.
DE3872754D1 (de) Nachweis von antikoerpern humaner immundefizienz-viren.
NO870476L (no) Fremgangsmaate for fremstilling av kryss-beskyttende humane monoklonale antistoffpreparater.
NO944887L (no) Monoklonale antistoffer mot glykoprotein
ES8505406A1 (es) Procedimiento de obtener y aislar hibridomas secretores de anticuerpos, procedimiento de obtener anticuerpos y metodo de obtener polipeptidos
HUT77253A (hu) CD4-csalireceptorokat és rokonszerkezetű molekulákat hordozó sejtek és alkalmazásuk
FI885868A7 (fi) Menetelmä immuunikatoviruksen vasta-aineiden havaitsemiseksi
TR27329A (tr) Yeni metazoan parazit antigenler, bunlari kodlayan nükleik asidler.
BE888855A (fr) Procede d'obtention de preparations de toxoplasmes pour le diagnostic de la toxoplasmose, et preparations ainsi obtenues
EP0418347A4 (en) Human monoclonal antibodies to human immunodeficiency virus
FI915333A7 (fi) T-lymfotrooppisten retrovirusten monoklonaalisia vasta-aineita
ATE147759T1 (de) Verfahren und materialien zum nachweis und therapie von hiv
FI870500A7 (fi) Reagenssi virus-antigeenin vasta-aineen määrittämiseksi.
MD950343A (ro) Metodă de diagnosticare a leucozei
DE3787927D1 (de) Kleine Peptide, die die Bindung an T-4-Rezeptoren inhibieren und als Immunogene wirken.
Zhang et al. AChR specific T lymphocytes in Myasthenia Gravis
RU95122100A (ru) Способ иммунокоррекции носителя патогена
AU1508088A (en) Monoclonal antibodies to specific antigenic regions of the human immunodeficiency virus and methods for use
KR880010133A (ko) Hiv 검출 및 치료를 위한 방법 및 물질
MW5888A1 (en) Method for detecting antibodies to human immunodeficiency virus

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired