DK475286A - N-substituerede piperidiner - Google Patents

N-substituerede piperidiner Download PDF

Info

Publication number
DK475286A
DK475286A DK475286A DK475286A DK475286A DK 475286 A DK475286 A DK 475286A DK 475286 A DK475286 A DK 475286A DK 475286 A DK475286 A DK 475286A DK 475286 A DK475286 A DK 475286A
Authority
DK
Denmark
Prior art keywords
substituted piperidines
piperidines
substituted
Prior art date
Application number
DK475286A
Other languages
English (en)
Other versions
DK475286D0 (da
DK168291B1 (da
Inventor
John Guilfoyle Mullin
Richard Wightman Kierstead
Joseph Triscari
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK475286D0 publication Critical patent/DK475286D0/da
Publication of DK475286A publication Critical patent/DK475286A/da
Application granted granted Critical
Publication of DK168291B1 publication Critical patent/DK168291B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK475286A 1985-10-07 1986-10-03 N-substituerede diphenylpiperidiner, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelserne samt anvendelse af forbindelserne samt anvendelse af forbindelserne til fremstilling af et lægemiddel til anvendelse til forebyggelse eller behandling af fedme DK168291B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/785,113 US4632925A (en) 1985-10-07 1985-10-07 N-substituted diphenylpiperidines and antiobesity use thereof
US78511385 1985-10-07

Publications (3)

Publication Number Publication Date
DK475286D0 DK475286D0 (da) 1986-10-03
DK475286A true DK475286A (da) 1987-04-08
DK168291B1 DK168291B1 (da) 1994-03-07

Family

ID=25134481

Family Applications (1)

Application Number Title Priority Date Filing Date
DK475286A DK168291B1 (da) 1985-10-07 1986-10-03 N-substituerede diphenylpiperidiner, fremgangsmåde til fremstilling deraf, lægemiddel indeholdende forbindelserne samt anvendelse af forbindelserne samt anvendelse af forbindelserne til fremstilling af et lægemiddel til anvendelse til forebyggelse eller behandling af fedme

Country Status (23)

Country Link
US (1) US4632925A (da)
EP (1) EP0221376B1 (da)
JP (1) JPH0633254B2 (da)
KR (1) KR870003984A (da)
AR (1) AR241422A1 (da)
AT (1) ATE53997T1 (da)
AU (1) AU593844B2 (da)
CA (1) CA1281326C (da)
DE (1) DE3672134D1 (da)
DK (1) DK168291B1 (da)
ES (1) ES2005074A6 (da)
FI (1) FI85020C (da)
GR (1) GR862513B (da)
HU (1) HU196200B (da)
IE (1) IE59434B1 (da)
IL (1) IL80232A0 (da)
MC (1) MC1769A1 (da)
NO (1) NO166127C (da)
NZ (1) NZ217798A (da)
PH (1) PH24167A (da)
PT (1) PT83495B (da)
SG (1) SG17593G (da)
ZA (1) ZA867375B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN163948B (da) * 1986-01-17 1988-12-10 Robins Co Inc A H
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
ATE122673T1 (de) * 1990-10-10 1995-06-15 Schering Corp Pyridin- und pyridin-n-oxid-derivate von diarylmethyl- piperidinen oder piperazinen, deren zusammensetzungen und anwendung.
DE69303605T2 (de) * 1992-03-27 1997-01-23 Schering Corp Unverbrückte bis-aryl-carbinol-derivate, zusammensetzungen und ihre verwendung
CA2128044C (en) * 1993-08-05 2007-02-20 Klaus-Dieter Bremer Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
US6017931A (en) * 1994-03-01 2000-01-25 Fmc Corporation Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6184234B1 (en) * 1994-03-01 2001-02-06 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
US5639763A (en) * 1994-03-01 1997-06-17 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6030987A (en) * 1996-05-17 2000-02-29 Fmc Corporation Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
BR9608794A (pt) * 1995-05-19 1999-02-17 Fmc Corp Composto composição contendo uma quantidade inseticidamente eficaz do composto e processo para controlar insetos
EP1975177B1 (en) * 1996-03-01 2011-04-13 Novo Nordisk A/S An appetite-suppressing peptide, its compositions and use
US6407116B1 (en) 1997-09-16 2002-06-18 Takeda Chemical Industries, Inc. Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs
KR100572785B1 (ko) * 2000-07-28 2006-04-19 에프. 호프만-라 로슈 아게 신규한 약학 조성물
US20100064413A1 (en) * 2008-03-14 2010-03-18 Simply Weights, LLC Exercise clothing and accessories
WO2009132978A1 (en) 2008-04-29 2009-11-05 F. Hoffmann-La Roche Ag 4-dimethylaminobutyric acid derivatives
CA2722114A1 (en) * 2008-04-29 2009-11-05 F. Hoffmann-La Roche Ag 4-trimethylammonio-butyrates as cpt2 inhibitors
EP3737680A1 (en) 2018-01-08 2020-11-18 F. Hoffmann-La Roche AG Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors
CN114072405A (zh) 2019-07-03 2022-02-18 豪夫迈·罗氏有限公司 杂环单酰基甘油脂肪酶(magl)抑制剂
KR20220034104A (ko) 2019-07-09 2022-03-17 에프. 호프만-라 로슈 아게 신규 헤테로고리 화합물
PE20231372A1 (es) 2020-09-03 2023-09-07 Hoffmann La Roche Compuestos heterociclicos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4076717A (en) * 1971-12-15 1978-02-28 G. D. Searle & Co. Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
US3931197A (en) * 1974-02-08 1976-01-06 Richardson-Merrell Inc. Substituted piperidine derivatives
US4650874A (en) * 1984-11-26 1987-03-17 G. D. Searle & Co. N-(aralkoxybenzyl)-4(benzhydryl) piperidines

Also Published As

Publication number Publication date
SG17593G (en) 1993-05-21
ATE53997T1 (de) 1990-07-15
IL80232A0 (en) 1987-01-30
PH24167A (en) 1990-03-22
ZA867375B (en) 1987-05-27
NZ217798A (en) 1989-10-27
EP0221376B1 (de) 1990-06-20
NO863978D0 (no) 1986-10-06
HU196200B (en) 1988-10-28
ES2005074A6 (es) 1989-03-01
IE59434B1 (en) 1994-02-23
EP0221376A2 (de) 1987-05-13
DK475286D0 (da) 1986-10-03
GR862513B (en) 1987-02-09
AR241422A1 (es) 1992-07-31
MC1769A1 (fr) 1987-07-17
KR870003984A (ko) 1987-05-06
AU593844B2 (en) 1990-02-22
AU6350186A (en) 1987-04-09
FI864051A0 (fi) 1986-10-07
NO863978L (no) 1987-04-08
DE3672134D1 (de) 1990-07-26
US4632925A (en) 1986-12-30
FI85020B (fi) 1991-11-15
FI864051L (fi) 1987-04-08
IE862636L (en) 1987-04-07
JPS6287585A (ja) 1987-04-22
NO166127B (no) 1991-02-25
CA1281326C (en) 1991-03-12
HUT41768A (en) 1987-05-28
EP0221376A3 (en) 1987-09-02
PT83495A (en) 1986-11-01
JPH0633254B2 (ja) 1994-05-02
DK168291B1 (da) 1994-03-07
FI85020C (fi) 1992-02-25
NO166127C (no) 1991-06-05
PT83495B (pt) 1989-05-31

Similar Documents

Publication Publication Date Title
DE122005000002I2 (de) 3-Aryloxy-3-substituierte-propanamine
DK64386D0 (da) Piperidinforbindelser
DK475286D0 (da) N-substituerede piperidiner
DK456987D0 (da) Piperidinderivater
DK674487A (da) Piperidinderivater
BR8600694A (pt) Conjunto alternador-compressor
DE3854938D1 (de) 4-Phenyl-4-(N-(2-fluorophenyl)amido)piperidin-Derivate
DE3571612D1 (de) N-(aralkoxybenzyl)-4(benzhydryl) piperidines
DK15686D0 (da) Dihydropyridinderivater
DK64286A (da) Dihydropyridinderivater
DE3565677D1 (de) N-substituted butyramide derivatives
DK224786D0 (da) Dihydropyridinderivater
DE3663668D1 (de) 2-oxa- or aza-pregnane compounds
NO850386L (no) N-substituerte aminopropansulfonsyrederivater
DK295486A (da) Lactamderivater
SE8406185D0 (sv) Novel n-substituted dihydropyridines
ES284745Y (es) Grapa
SE8503611D0 (sv) Klammer
KR860010562U (ko) 스테이풀
DK372486D0 (da) 1-(2-oxyaminosulfonylphenylsulfonyl)-3-triazinyl-urinstoffer
KR860011992U (ko) 개량 경첩
KR860011373U (ko) 다기함 겸용상
KR860014928U (ko) 괘지구를 갖는 경첩
IT8535301V0 (it) Morsa reggiprosciutto
BR8505307A (pt) Conjunto didatico