NO166127C - Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte difenylpiperidiner. - Google Patents

Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte difenylpiperidiner.

Info

Publication number: NO166127C
Authority: NO; Norway
Prior art keywords: piperidines; preparation; therapeutically active; substituted diphenyl; analogy procedure
Prior art date: 1985-10-07

Application number

NO863978A

Other languages

English (en)

Norwegian (no)

Other versions

NO863978D0 (no

NO863978L (no

NO166127B (no

Inventor

John Guilfoyle Mullin

Joseph Triscari

Richard Wightman Kierstead

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-07

Filing date

1986-10-06

Publication date

1991-06-05

1986-10-06 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1986-10-06 Publication of NO863978D0 publication Critical patent/NO863978D0/no

1987-04-08 Publication of NO863978L publication Critical patent/NO863978L/no

1991-02-25 Publication of NO166127B publication Critical patent/NO166127B/no

1991-06-05 Publication of NO166127C publication Critical patent/NO166127C/no

Links

-1 DIPHENYL PIPERIDINES Chemical class 0.000 title 1
235000010290 biphenyl Nutrition 0.000 title 1
239000004305 biphenyl Substances 0.000 title 1
ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO863978A 1985-10-07 1986-10-06 Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte difenylpiperidiner. NO166127C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/785,113 US4632925A (en)	1985-10-07	1985-10-07	N-substituted diphenylpiperidines and antiobesity use thereof

Publications (4)

Publication Number	Publication Date
NO863978D0 NO863978D0 (no)	1986-10-06
NO863978L NO863978L (no)	1987-04-08
NO166127B NO166127B (no)	1991-02-25
NO166127C true NO166127C (no)	1991-06-05

Family

ID=25134481

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO863978A NO166127C (no)	1985-10-07	1986-10-06	Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte difenylpiperidiner.

Country Status (23)

Country	Link
US (1)	US4632925A (da)
EP (1)	EP0221376B1 (da)
JP (1)	JPH0633254B2 (da)
KR (1)	KR870003984A (da)
AR (1)	AR241422A1 (da)
AT (1)	ATE53997T1 (da)
AU (1)	AU593844B2 (da)
CA (1)	CA1281326C (da)
DE (1)	DE3672134D1 (da)
DK (1)	DK168291B1 (da)
ES (1)	ES2005074A6 (da)
FI (1)	FI85020C (da)
GR (1)	GR862513B (da)
HU (1)	HU196200B (da)
IE (1)	IE59434B1 (da)
IL (1)	IL80232A0 (da)
MC (1)	MC1769A1 (da)
NO (1)	NO166127C (da)
NZ (1)	NZ217798A (da)
PH (1)	PH24167A (da)
PT (1)	PT83495B (da)
SG (1)	SG17593G (da)
ZA (1)	ZA867375B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN163948B (da) *	1986-01-17	1988-12-10	Robins Co Inc A H
GB9000305D0 (en) *	1990-01-06	1990-03-07	Pfizer Ltd	Anticholinergic agents
ATE122673T1 (de) *	1990-10-10	1995-06-15	Schering Corp	Pyridin- und pyridin-n-oxid-derivate von diarylmethyl- piperidinen oder piperazinen, deren zusammensetzungen und anwendung.
DE69303605T2 (de) *	1992-03-27	1997-01-23	Schering Corp	Unverbrückte bis-aryl-carbinol-derivate, zusammensetzungen und ihre verwendung
CA2128044C (en) *	1993-08-05	2007-02-20	Klaus-Dieter Bremer	Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
US6017931A (en) *	1994-03-01	2000-01-25	Fmc Corporation	Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6184234B1 (en) *	1994-03-01	2001-02-06	Fmc Corporation	Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
US5639763A (en) *	1994-03-01	1997-06-17	Fmc Corporation	Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6030987A (en) *	1996-05-17	2000-02-29	Fmc Corporation	Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
BR9608794A (pt) *	1995-05-19	1999-02-17	Fmc Corp	Composto composição contendo uma quantidade inseticidamente eficaz do composto e processo para controlar insetos
EP1975177B1 (en) *	1996-03-01	2011-04-13	Novo Nordisk A/S	An appetite-suppressing peptide, its compositions and use
US6407116B1 (en)	1997-09-16	2002-06-18	Takeda Chemical Industries, Inc.	Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs
KR100572785B1 (ko) *	2000-07-28	2006-04-19	에프. 호프만-라 로슈 아게	신규한 약학 조성물
US20100064413A1 (en) *	2008-03-14	2010-03-18	Simply Weights, LLC	Exercise clothing and accessories
WO2009132978A1 (en)	2008-04-29	2009-11-05	F. Hoffmann-La Roche Ag	4-dimethylaminobutyric acid derivatives
CA2722114A1 (en) *	2008-04-29	2009-11-05	F. Hoffmann-La Roche Ag	4-trimethylammonio-butyrates as cpt2 inhibitors
EP3737680A1 (en)	2018-01-08	2020-11-18	F. Hoffmann-La Roche AG	Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors
CN114072405A (zh)	2019-07-03	2022-02-18	豪夫迈·罗氏有限公司	杂环单酰基甘油脂肪酶(magl)抑制剂
KR20220034104A (ko)	2019-07-09	2022-03-17	에프. 호프만-라 로슈 아게	신규 헤테로고리 화합물
PE20231372A1 (es)	2020-09-03	2023-09-07	Hoffmann La Roche	Compuestos heterociclicos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4076717A (en) *	1971-12-15	1978-02-28	G. D. Searle & Co.	Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
US3931197A (en) *	1974-02-08	1976-01-06	Richardson-Merrell Inc.	Substituted piperidine derivatives
US4650874A (en) *	1984-11-26	1987-03-17	G. D. Searle & Co.	N-(aralkoxybenzyl)-4(benzhydryl) piperidines

1985
- 1985-10-07 US US06/785,113 patent/US4632925A/en not_active Expired - Fee Related
1986
- 1986-09-26 ZA ZA867375A patent/ZA867375B/xx unknown
- 1986-10-03 DK DK475286A patent/DK168291B1/da active
- 1986-10-03 CA CA000519718A patent/CA1281326C/en not_active Expired - Lifetime
- 1986-10-03 HU HU864167A patent/HU196200B/hu not_active IP Right Cessation
- 1986-10-03 NZ NZ217798A patent/NZ217798A/xx unknown
- 1986-10-03 IL IL80232A patent/IL80232A0/xx not_active IP Right Cessation
- 1986-10-03 AU AU63501/86A patent/AU593844B2/en not_active Ceased
- 1986-10-06 IE IE263686A patent/IE59434B1/en not_active IP Right Cessation
- 1986-10-06 AT AT86113837T patent/ATE53997T1/de not_active IP Right Cessation
- 1986-10-06 PT PT83495A patent/PT83495B/pt not_active IP Right Cessation
- 1986-10-06 EP EP86113837A patent/EP0221376B1/de not_active Expired - Lifetime
- 1986-10-06 NO NO863978A patent/NO166127C/no unknown
- 1986-10-06 ES ES8602424A patent/ES2005074A6/es not_active Expired
- 1986-10-06 DE DE8686113837T patent/DE3672134D1/de not_active Expired - Lifetime
- 1986-10-06 JP JP61236364A patent/JPH0633254B2/ja not_active Expired - Lifetime
- 1986-10-06 MC MC861851A patent/MC1769A1/fr unknown
- 1986-10-07 FI FI864051A patent/FI85020C/fi not_active IP Right Cessation
- 1986-10-07 PH PH34329A patent/PH24167A/en unknown
- 1986-10-07 KR KR1019860008388A patent/KR870003984A/ko not_active Ceased
- 1986-10-07 GR GR862513A patent/GR862513B/el unknown
- 1986-10-23 AR AR86305473A patent/AR241422A1/es active
1993
- 1993-02-17 SG SG175/93A patent/SG17593G/en unknown

Also Published As

Publication number	Publication date
SG17593G (en)	1993-05-21
ATE53997T1 (de)	1990-07-15
IL80232A0 (en)	1987-01-30
PH24167A (en)	1990-03-22
ZA867375B (en)	1987-05-27
NZ217798A (en)	1989-10-27
EP0221376B1 (de)	1990-06-20
NO863978D0 (no)	1986-10-06
HU196200B (en)	1988-10-28
ES2005074A6 (es)	1989-03-01
IE59434B1 (en)	1994-02-23
EP0221376A2 (de)	1987-05-13
DK475286D0 (da)	1986-10-03
GR862513B (en)	1987-02-09
AR241422A1 (es)	1992-07-31
MC1769A1 (fr)	1987-07-17
KR870003984A (ko)	1987-05-06
AU593844B2 (en)	1990-02-22
AU6350186A (en)	1987-04-09
FI864051A0 (fi)	1986-10-07
NO863978L (no)	1987-04-08
DE3672134D1 (de)	1990-07-26
US4632925A (en)	1986-12-30
FI85020B (fi)	1991-11-15
FI864051L (fi)	1987-04-08
IE862636L (en)	1987-04-07
JPS6287585A (ja)	1987-04-22
NO166127B (no)	1991-02-25
CA1281326C (en)	1991-03-12
HUT41768A (en)	1987-05-28
EP0221376A3 (en)	1987-09-02
PT83495A (en)	1986-11-01
JPH0633254B2 (ja)	1994-05-02
DK168291B1 (da)	1994-03-07
FI85020C (fi)	1992-02-25
PT83495B (pt)	1989-05-31
DK475286A (da)	1987-04-08

Publication	Publication Date	Title
NO159089C (no)	1988-11-30	Analogifremgangsmaate ved fremstilling av terapeutisk aktive glutarimidderivater.
NO173544C (no)	1993-12-29	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 2- tiometyl-substituerte 1,4-dihydropyridiner
NO169543C (no)	1992-07-08	Analogifremgangsmaate ved fremstilling av terapeutisk aktive peptidaseinhibitorer
NO168422C (no)	1992-02-19	Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-substituerte benzamider
NO864879D0 (no)	1986-12-04	Fremgangsmaate for fremstilling av terapeutisk aktive tiasolforbindelser.
NO162858C (no)	1990-02-28	Analogifremgangsmaate ved fremstilling av terapeutisk aktive thiazolidinderivater.
NO165841C (no)	1991-04-17	Analogifremgangsmaate ved fremstilling av terapeutisk aktive heteroaryl-3-okso-propannitril-derivater.
NO166083C (no)	1991-05-29	Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyridazodiazepinderivater.
NO167569C (no)	1991-11-20	Analogifremgangsmaate for fremstilling av terapeutisk virksomme benzimidazolderivater.
NO862373D0 (no)	1986-06-13	Fremgangsmaate for fremstilling av terapeutisk aktive tienopyridoner.
NO167912C (no)	1991-12-27	Analogifremgangsmaate ved fremstilling av terapeutisk aktive aromatiske forbindelser
NO168107C (no)	1992-01-15	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1,4-dihydropyridiner
NO166326C (no)	1991-07-03	Fremgangsmaate ved fremstilling av terapeutisk aktive 3,7-substituerte-8-oxo-5-thia-1-azabicyclo-(4,2,0)oct-2-en-2-carboxylater.
NO165400C (no)	1991-02-06	Analogifremgangsmaate ved fremstilling av terapeutisk aktive cefemforbindelser.
NO167570C (no)	1991-11-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive flavonforbindelser.
NO168706C (no)	1992-03-25	Analogifremgangsmaate ved fremstilling av terapeutisk aktive n-heterosyklisk substituerte benzamider.
NO165842C (no)	1991-04-17	Analogifremgangsmaate for fremstilling av terapeutisk aktive cefem-forbindelser.
NO164020C (no)	1990-08-22	Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenetanolaminderivater.
NO165069C (no)	1990-12-19	Analogifremgangsmaate for fremstilling av terapeutisk aktive cyklopentyletere.
NO168105C (no)	1992-01-15	Analogifremgangsmaate ved fremstilling av terapeutisk aktive pyridinsubstituerte oxazoloner
NO161313C (no)	1989-08-02	Analogifremgangsmaate ved fremstilling av terapeutisk aktive fluorallylaminderivater.
NO163330C (no)	1990-05-09	Analogifremgangsmaate ved fremstilling av terapeutisk aktive isokinolinderivater.
NO158673C (no)	1988-10-19	Analogifremgangsmaate ved fremstilling av terapeutisk aktive azurenderivater.
NO167923C (no)	1991-12-27	Analogifremgangsmaate for fremstilling av terapeutisk aktive peptidsubstituerte heterocykliske forbindelser
NO862390D0 (no)	1986-06-16	Fremgangsmaate for fremstilling av terapeutisk aktive 1,4-dihydropyridinderivater.