IL80232A0 - N-substituted diphenylpiperidines,their manufacture and pharmaceutical compositions containing them - Google Patents

N-substituted diphenylpiperidines,their manufacture and pharmaceutical compositions containing them

Info

Publication number: IL80232A0
Authority: IL; Israel
Prior art keywords: diphenylpiperidines; substituted; manufacture; pharmaceutical compositions; compositions containing
Prior art date: 1985-10-07

Application number

IL80232A

Other languages

English (en)

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-10-07

Filing date

1986-10-03

Publication date

1987-01-30

1986-10-03 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1987-01-30 Publication of IL80232A0 publication Critical patent/IL80232A0/xx

Links

238000004519 manufacturing process Methods 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Hydrogenated Pyridines (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL80232A 1985-10-07 1986-10-03 N-substituted diphenylpiperidines,their manufacture and pharmaceutical compositions containing them IL80232A0 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/785,113 US4632925A (en)	1985-10-07	1985-10-07	N-substituted diphenylpiperidines and antiobesity use thereof

Publications (1)

Publication Number	Publication Date
IL80232A0 true IL80232A0 (en)	1987-01-30

Family

ID=25134481

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL80232A IL80232A0 (en)	1985-10-07	1986-10-03	N-substituted diphenylpiperidines,their manufacture and pharmaceutical compositions containing them

Country Status (23)

Country	Link
US (1)	US4632925A (da)
EP (1)	EP0221376B1 (da)
JP (1)	JPH0633254B2 (da)
KR (1)	KR870003984A (da)
AR (1)	AR241422A1 (da)
AT (1)	ATE53997T1 (da)
AU (1)	AU593844B2 (da)
CA (1)	CA1281326C (da)
DE (1)	DE3672134D1 (da)
DK (1)	DK168291B1 (da)
ES (1)	ES2005074A6 (da)
FI (1)	FI85020C (da)
GR (1)	GR862513B (da)
HU (1)	HU196200B (da)
IE (1)	IE59434B1 (da)
IL (1)	IL80232A0 (da)
MC (1)	MC1769A1 (da)
NO (1)	NO166127C (da)
NZ (1)	NZ217798A (da)
PH (1)	PH24167A (da)
PT (1)	PT83495B (da)
SG (1)	SG17593G (da)
ZA (1)	ZA867375B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN163948B (da) *	1986-01-17	1988-12-10	Robins Co Inc A H
GB9000305D0 (en) *	1990-01-06	1990-03-07	Pfizer Ltd	Anticholinergic agents
ATE122673T1 (de) *	1990-10-10	1995-06-15	Schering Corp	Pyridin- und pyridin-n-oxid-derivate von diarylmethyl- piperidinen oder piperazinen, deren zusammensetzungen und anwendung.
DE69303605T2 (de) *	1992-03-27	1997-01-23	Schering Corp	Unverbrückte bis-aryl-carbinol-derivate, zusammensetzungen und ihre verwendung
CA2128044C (en) *	1993-08-05	2007-02-20	Klaus-Dieter Bremer	Pharmaceutical compositions comprising a glucosidase and/or amylase inhibitor, and a lipase inhibitor
US6017931A (en) *	1994-03-01	2000-01-25	Fmc Corporation	Insecticidal compositions containing n-(substituted phenylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6184234B1 (en) *	1994-03-01	2001-02-06	Fmc Corporation	Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
US5639763A (en) *	1994-03-01	1997-06-17	Fmc Corporation	Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl)methyl]piperidines
US6030987A (en) *	1996-05-17	2000-02-29	Fmc Corporation	Insecticidal N-(substituted arylmethyl)-4-[bis(substituted phenyl or pyridyl)methyl]piperidines
BR9608794A (pt) *	1995-05-19	1999-02-17	Fmc Corp	Composto composição contendo uma quantidade inseticidamente eficaz do composto e processo para controlar insetos
EP1975177B1 (en) *	1996-03-01	2011-04-13	Novo Nordisk A/S	An appetite-suppressing peptide, its compositions and use
US6407116B1 (en)	1997-09-16	2002-06-18	Takeda Chemical Industries, Inc.	Nitrogenous fused-ring compounds, process for the preparation of the same, and drugs
KR100572785B1 (ko) *	2000-07-28	2006-04-19	에프. 호프만-라 로슈 아게	신규한 약학 조성물
US20100064413A1 (en) *	2008-03-14	2010-03-18	Simply Weights, LLC	Exercise clothing and accessories
WO2009132978A1 (en)	2008-04-29	2009-11-05	F. Hoffmann-La Roche Ag	4-dimethylaminobutyric acid derivatives
CA2722114A1 (en) *	2008-04-29	2009-11-05	F. Hoffmann-La Roche Ag	4-trimethylammonio-butyrates as cpt2 inhibitors
EP3737680A1 (en)	2018-01-08	2020-11-18	F. Hoffmann-La Roche AG	Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors
CN114072405A (zh)	2019-07-03	2022-02-18	豪夫迈·罗氏有限公司	杂环单酰基甘油脂肪酶(magl)抑制剂
KR20220034104A (ko)	2019-07-09	2022-03-17	에프. 호프만-라 로슈 아게	신규 헤테로고리 화합물
PE20231372A1 (es)	2020-09-03	2023-09-07	Hoffmann La Roche	Compuestos heterociclicos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4076717A (en) *	1971-12-15	1978-02-28	G. D. Searle & Co.	Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid
US3931197A (en) *	1974-02-08	1976-01-06	Richardson-Merrell Inc.	Substituted piperidine derivatives
US4650874A (en) *	1984-11-26	1987-03-17	G. D. Searle & Co.	N-(aralkoxybenzyl)-4(benzhydryl) piperidines

1985
- 1985-10-07 US US06/785,113 patent/US4632925A/en not_active Expired - Fee Related
1986
- 1986-09-26 ZA ZA867375A patent/ZA867375B/xx unknown
- 1986-10-03 DK DK475286A patent/DK168291B1/da active
- 1986-10-03 CA CA000519718A patent/CA1281326C/en not_active Expired - Lifetime
- 1986-10-03 HU HU864167A patent/HU196200B/hu not_active IP Right Cessation
- 1986-10-03 NZ NZ217798A patent/NZ217798A/xx unknown
- 1986-10-03 IL IL80232A patent/IL80232A0/xx not_active IP Right Cessation
- 1986-10-03 AU AU63501/86A patent/AU593844B2/en not_active Ceased
- 1986-10-06 IE IE263686A patent/IE59434B1/en not_active IP Right Cessation
- 1986-10-06 AT AT86113837T patent/ATE53997T1/de not_active IP Right Cessation
- 1986-10-06 PT PT83495A patent/PT83495B/pt not_active IP Right Cessation
- 1986-10-06 EP EP86113837A patent/EP0221376B1/de not_active Expired - Lifetime
- 1986-10-06 NO NO863978A patent/NO166127C/no unknown
- 1986-10-06 ES ES8602424A patent/ES2005074A6/es not_active Expired
- 1986-10-06 DE DE8686113837T patent/DE3672134D1/de not_active Expired - Lifetime
- 1986-10-06 JP JP61236364A patent/JPH0633254B2/ja not_active Expired - Lifetime
- 1986-10-06 MC MC861851A patent/MC1769A1/fr unknown
- 1986-10-07 FI FI864051A patent/FI85020C/fi not_active IP Right Cessation
- 1986-10-07 PH PH34329A patent/PH24167A/en unknown
- 1986-10-07 KR KR1019860008388A patent/KR870003984A/ko not_active Ceased
- 1986-10-07 GR GR862513A patent/GR862513B/el unknown
- 1986-10-23 AR AR86305473A patent/AR241422A1/es active
1993
- 1993-02-17 SG SG175/93A patent/SG17593G/en unknown

Also Published As

Publication number	Publication date
SG17593G (en)	1993-05-21
ATE53997T1 (de)	1990-07-15
PH24167A (en)	1990-03-22
ZA867375B (en)	1987-05-27
NZ217798A (en)	1989-10-27
EP0221376B1 (de)	1990-06-20
NO863978D0 (no)	1986-10-06
HU196200B (en)	1988-10-28
ES2005074A6 (es)	1989-03-01
IE59434B1 (en)	1994-02-23
EP0221376A2 (de)	1987-05-13
DK475286D0 (da)	1986-10-03
GR862513B (en)	1987-02-09
AR241422A1 (es)	1992-07-31
MC1769A1 (fr)	1987-07-17
KR870003984A (ko)	1987-05-06
AU593844B2 (en)	1990-02-22
AU6350186A (en)	1987-04-09
FI864051A0 (fi)	1986-10-07
NO863978L (no)	1987-04-08
DE3672134D1 (de)	1990-07-26
US4632925A (en)	1986-12-30
FI85020B (fi)	1991-11-15
FI864051L (fi)	1987-04-08
IE862636L (en)	1987-04-07
JPS6287585A (ja)	1987-04-22
NO166127B (no)	1991-02-25
CA1281326C (en)	1991-03-12
HUT41768A (en)	1987-05-28
EP0221376A3 (en)	1987-09-02
PT83495A (en)	1986-11-01
JPH0633254B2 (ja)	1994-05-02
DK168291B1 (da)	1994-03-07
FI85020C (fi)	1992-02-25
NO166127C (no)	1991-06-05
PT83495B (pt)	1989-05-31
DK475286A (da)	1987-04-08

Legal Events

Date	Code	Title	Description
1997-08-14	RH	Patent void

Publication	Publication Date	Title
IL79323A (en)	1990-03-19	Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them
IL78079A0 (en)	1986-07-31	Sulphonylaminoethyl compounds,their preparation and pharmaceutical compositions containing them
IL80296A (en)	1990-06-10	Phenylpyridone derivatives,their preparation and pharmaceutical compositions containing them
IL77004A0 (en)	1986-04-29	5-amino-4-hydroxyvaleryl derivatives,their manufacture and pharmaceutical compositions containing them
NZ218089A (en)	1989-03-29	7-piperazinyl, 4-oxoquinolines and pharmaceutical compositions
IL79309A (en)	1990-11-29	(heterocyclic substituted-phenoxy)alkyl-isoxazoles and-furans,their preparation and pharmaceutical compositions containing them
NZ217798A (en)	1989-10-27	N-substituted diphenylpiperidines and pharmaceutical compositions
IL79376A0 (en)	1986-10-31	Substituted di-t-butylphenols and pharmaceutical compositions containing them
IL78939A0 (en)	1986-09-30	N-substituted arylalkyl-and arylalkylene-aminoheterocyclics and pharmaceutical compositions containing them
IL79402A0 (en)	1986-10-31	Poly-4-aminopyrrole-2-carboxamido derivatives,their preparation and pharmaceutical compositions containing them
IL80394A0 (en)	1987-01-30	Antihypertensive thieno-isoxazoles and thieno-pyrazoles,process for their preparation and pharmaceutical compositions containing them
IL79469A0 (en)	1986-10-31	Substituted benzamides,their preparation and pharmaceutical compositions containing them
IL79039A0 (en)	1986-09-30	4-oxoquinolinesulfonamides,their preparation and pharmaceutical compositions containing them
IL75966A (en)	1989-08-15	3-substituted-1-aminoalkyl-1h-indoles,their preparation and pharmaceutical compositions containing them
IL77565A (en)	1988-12-30	Polycyclic salts,their manufacture and pharmaceutical compositions containing them
IL79003A0 (en)	1986-09-30	Tetrahydroimidazoquinazolinones and pharmaceutical compositions containing them
IL76312A (en)	1991-06-10	Xenocoumacins and derivatives thereof,their preparation and pharmaceutical compositions containing them
DE3573784D1 (en)	1989-11-23	Carboxyalkyldipeptides, their preparation and pharmaceutical compositions containing them
NZ217248A (en)	1989-05-29	Gem-dihalo-1,8-diamino-4-aza-octones and pharmaceutical compositions
IL81010A0 (en)	1987-03-31	Substituted benzamides,their preparation and pharmaceutical compositions containing them
IL78918A0 (en)	1986-09-30	Substituted hexahydro-arylquinolizines and pharmaceutical compositions containing them
IL79377A0 (en)	1986-10-31	Substituted di-t-butylphenols and pharmaceutical compositions containing them
IL74042A0 (en)	1985-04-30	N-(naphthyl-alkyl)-hydroxylamines,their production and pharmaceutical compositions containing them
IL88673A0 (en)	1989-07-31	N-hydroxy-5-phenyl-2-furancarboxi-midamides,and pharmaceutical compositions containing them
IL79241A0 (en)	1986-09-30	Benzamides,their preparation and pharmaceutical compositions containing them