DK644889A - Leukotrienantagonister - Google Patents

Leukotrienantagonister Download PDF

Info

Publication number
DK644889A
DK644889A DK644889A DK644889A DK644889A DK 644889 A DK644889 A DK 644889A DK 644889 A DK644889 A DK 644889A DK 644889 A DK644889 A DK 644889A DK 644889 A DK644889 A DK 644889A
Authority
DK
Denmark
Prior art keywords
phenyl
alkyl
leukotriene antagonists
tetrazoyl
aryl
Prior art date
Application number
DK644889A
Other languages
Danish (da)
English (en)
Other versions
DK644889D0 (da
Inventor
John Gerald Gleason
Ralph Floyd Hall
Joanne Marie Smallheer
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of DK644889D0 publication Critical patent/DK644889D0/da
Publication of DK644889A publication Critical patent/DK644889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK644889A 1988-12-23 1989-12-19 Leukotrienantagonister DK644889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/288,827 US4954513A (en) 1988-12-23 1988-12-23 Leukotriene antagonists

Publications (2)

Publication Number Publication Date
DK644889D0 DK644889D0 (da) 1989-12-19
DK644889A true DK644889A (da) 1990-06-24

Family

ID=23108809

Family Applications (1)

Application Number Title Priority Date Filing Date
DK644889A DK644889A (da) 1988-12-23 1989-12-19 Leukotrienantagonister

Country Status (12)

Country Link
US (1) US4954513A (de)
EP (1) EP0375348B1 (de)
JP (1) JPH0684344B2 (de)
AT (1) ATE90940T1 (de)
AU (1) AU4678789A (de)
CA (1) CA2005349A1 (de)
DE (1) DE68907329T2 (de)
DK (1) DK644889A (de)
ES (1) ES2057153T3 (de)
IE (1) IE894104L (de)
PT (1) PT92724A (de)
ZA (1) ZA899721B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2018437A1 (en) * 1989-06-14 1990-12-14 James Simpson Frazee Leukotriene antagonists
US5266713A (en) * 1989-07-27 1993-11-30 Miles Inc. Aryl alkenoic acid derivatives as leukotriene antagonists
DK0410241T3 (da) * 1989-07-27 1993-12-13 Bayer Ag Arylalkensyrederivater som leukotrienantagonister
EP0528957A4 (en) * 1990-05-01 1993-05-05 Smith-Kline Beecham Corporation Five-membered ring alkanoic acid leukotriene antagonists
CA2081480A1 (en) * 1990-05-01 1991-11-02 James S. Frazee 3-naphthyl-3-carboxyalkylthio or oxy substituted alkanoic acid leukotriene antagonists
WO2009001374A2 (en) * 2007-06-25 2008-12-31 Aptuit Laurus Pvt Ltd Preparation of ethyl-3'-[((7-chloro-2-quinolinyl)ethenyl)phenyl]-3-oxopropanoate, a key intermediate for montelukast sodium

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US66592A (en) * 1867-07-09 Geobge iewin
US66588A (en) * 1867-07-09 hicks
BE787235A (fr) * 1971-08-06 1973-02-05 Sandoz Sa Nouveaux derives du thiophene, leur preparation et leur application comme medicaments
GB1577550A (en) * 1976-10-18 1980-10-22 Sagami Chem Res -thio-alkanoic acid derivatives
US4513005A (en) * 1981-06-18 1985-04-23 Lilly Industries Limited SRS-A antagonists
IL69691A (en) * 1982-09-23 1988-01-31 Merck Frosst Canada Inc Leukotriene antagonists,their preparation and pharmaceutical compositions containing them
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
DE3469169D1 (en) * 1983-04-21 1988-03-10 Merck Frosst Canada Inc Leukotriene antagonists, their production and use and compositions containing them
US4609744A (en) * 1983-04-21 1986-09-02 Merck Frosst Canada Inc. 4-oxo-benzopyran carboxylic acids
GR81524B (de) * 1983-07-18 1984-12-11 Lilly Co Eli
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
GB8320943D0 (en) * 1983-08-03 1983-09-07 Lilly Industries Ltd Organic compounds
GB8432144D0 (en) * 1984-12-20 1985-01-30 Lilly Industries Ltd Organic compounds
GB8502258D0 (en) * 1985-01-30 1985-02-27 Lilly Industries Ltd Organic compounds
EP0358240B1 (de) * 1985-04-19 1993-06-09 Smithkline Beecham Corporation Zwischenprodukte für die Herstellung von Leukotrien-Antagonisten
GB8530222D0 (en) * 1985-12-07 1986-01-15 Lilly Industries Ltd Organic compounds
CA1334200C (en) * 1987-06-24 1995-01-31 James Simpson Frazee Leukotriene antagonists
AU610528B2 (en) * 1987-10-29 1991-05-23 Smithkline Beckman Corporation Leukotriene antagonists

Also Published As

Publication number Publication date
DK644889D0 (da) 1989-12-19
ATE90940T1 (de) 1993-07-15
US4954513A (en) 1990-09-04
EP0375348B1 (de) 1993-06-23
AU4678789A (en) 1990-06-28
ZA899721B (en) 1990-09-26
JPH0684344B2 (ja) 1994-10-26
ES2057153T3 (es) 1994-10-16
EP0375348A1 (de) 1990-06-27
CA2005349A1 (en) 1990-06-23
PT92724A (pt) 1990-06-29
JPH02215764A (ja) 1990-08-28
DE68907329D1 (de) 1993-07-29
IE894104L (en) 1990-06-23
DE68907329T2 (de) 1993-09-30

Similar Documents

Publication Publication Date Title
FI95469C (fi) Analogiamenetelmä uusien hypoglykeemisten oksatsolidiinidionien valmistamiseksi
ATE126517T1 (de) Verwendung von bis(3,4- dialkylbenzyliden)sorbitolacetale und diese enthaltende zusammensetzungen.
IT1216687B (it) Complessi di platino (ii), loro preparazione e impiego come antitumorali.
DE69728544D1 (de) Totalsynthese von acylfulvenen mit antitumorwirkung
ATE66240T1 (de) Phenolische korrosionsinhibitoren fuer anstrichstoffe.
FI860369A0 (fi) Imidazolderivat, deras framstaellning och anvaendning samt dessa derivat innehaollande farmaceutiska kompositioner.
DE68907329D1 (de) Leukotrien-antagonisten.
FI923033A0 (fi) N-fenyltioureaderivat och farmaceutisk anvaendning av dem.
FI925501A0 (fi) Imidazolfoereningar, deras framstaellning och anvaendning
ATE86860T1 (de) Praeparat gegen ulcus.
DE3778508D1 (de) Substituierte triazinderivate.
DK37691D0 (da) Substituerede beta-diketoner, farmaceutiske midler indeholdende disse forbindelser samt anvendelse deraf
NO894563L (no) Substituerte imidazolderivater og fremstilling og anvendelse derav.
ES2058275T3 (es) Derivados biciclicos de sulfonamida y su preparacion, su uso y formulaciones que los contienen.
NO875357D0 (no) Kjemiske sammensetninger og deres bruk som brennstoff additiver.
ATE92066T1 (de) Sulfonyldecahydro-8h-isochino(2,1g>(1,6>naphthyridine, optische isomere davon und verwandte verbindungen.
DK681187D0 (da) Forbindelse, der absorberer ultraviolet lys, samt praeparat indeholdende samme
NO895165D0 (no) Pyrazolopyridin-type mevalono-laktoner.
ATE97409T1 (de) Benzodiazepin-analoge.
DE69108195D1 (de) Astaxanthin-Zwischenprodukte.
DE69107080D1 (de) Organozinnverbindungen mit Antitumoraktivität und Zusammensetzungen mit Antitumorwirkung.
ES2058779T3 (es) Nitrato de piridinio, su produccion y uso.
NO980842D0 (no) Nye benzensulfonylaminforbindelser, fremgangsmåte ved fremstilling derav, samt farmasöytiske sammensetninger inneholdende slike
GB1118026A (en) í¸-pyrroline derivatives
ATE1585T1 (de) Clavulansaeurederivate, ihre herstellung und sie enthaltende pharmazeutische praeparate.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment