DK644889A - Leukotrienantagonister - Google Patents

Leukotrienantagonister Download PDF

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Publication number
DK644889A
DK644889A DK644889A DK644889A DK644889A DK 644889 A DK644889 A DK 644889A DK 644889 A DK644889 A DK 644889A DK 644889 A DK644889 A DK 644889A DK 644889 A DK644889 A DK 644889A
Authority
DK
Denmark
Prior art keywords
phenyl
alkyl
leukotriene antagonists
tetrazoyl
aryl
Prior art date
Application number
DK644889A
Other languages
Danish (da)
English (en)
Other versions
DK644889D0 (da
Inventor
John Gerald Gleason
Ralph Floyd Hall
Joanne Marie Smallheer
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of DK644889D0 publication Critical patent/DK644889D0/da
Publication of DK644889A publication Critical patent/DK644889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK644889A 1988-12-23 1989-12-19 Leukotrienantagonister DK644889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/288,827 US4954513A (en) 1988-12-23 1988-12-23 Leukotriene antagonists

Publications (2)

Publication Number Publication Date
DK644889D0 DK644889D0 (da) 1989-12-19
DK644889A true DK644889A (da) 1990-06-24

Family

ID=23108809

Family Applications (1)

Application Number Title Priority Date Filing Date
DK644889A DK644889A (da) 1988-12-23 1989-12-19 Leukotrienantagonister

Country Status (12)

Country Link
US (1) US4954513A (fr)
EP (1) EP0375348B1 (fr)
JP (1) JPH0684344B2 (fr)
AT (1) ATE90940T1 (fr)
AU (1) AU4678789A (fr)
CA (1) CA2005349A1 (fr)
DE (1) DE68907329T2 (fr)
DK (1) DK644889A (fr)
ES (1) ES2057153T3 (fr)
IE (1) IE894104L (fr)
PT (1) PT92724A (fr)
ZA (1) ZA899721B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2018437A1 (fr) * 1989-06-14 1990-12-14 James Simpson Frazee Antagonistes des leukotrienes
US5266713A (en) * 1989-07-27 1993-11-30 Miles Inc. Aryl alkenoic acid derivatives as leukotriene antagonists
ATE96149T1 (de) * 1989-07-27 1993-11-15 Bayer Ag Arylalkensaeurederivate als leukotrienantagonisten.
AU7769491A (en) * 1990-05-01 1991-11-27 Smithkline Beecham Corporation 3-naphthyl-3-carboxyalkylthio or oxy substituted alkanoic acid leukotriene antagonists
WO1991016889A1 (fr) * 1990-05-01 1991-11-14 Smithkline Beecham Corporation Antagonistes de leucotriene sous forme d'acide alcanoique a anneau de cinq membres
WO2009001374A2 (fr) * 2007-06-25 2008-12-31 Aptuit Laurus Pvt Ltd Préparation de éthyl-3'-[((7-chloro-2-quinolinyl)ethenyl)phényl]-3-oxopropanoate, clé intermédiaire pour le sodium de montelukast

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US66588A (en) * 1867-07-09 hicks
US66592A (en) * 1867-07-09 Geobge iewin
BE787235A (fr) * 1971-08-06 1973-02-05 Sandoz Sa Nouveaux derives du thiophene, leur preparation et leur application comme medicaments
GB1577550A (en) * 1976-10-18 1980-10-22 Sagami Chem Res -thio-alkanoic acid derivatives
US4513005A (en) * 1981-06-18 1985-04-23 Lilly Industries Limited SRS-A antagonists
IL69691A (en) * 1982-09-23 1988-01-31 Merck Frosst Canada Inc Leukotriene antagonists,their preparation and pharmaceutical compositions containing them
US4661505A (en) * 1982-11-03 1987-04-28 Eli Lilly And Company Leukotriene antagonists
US4609744A (en) * 1983-04-21 1986-09-02 Merck Frosst Canada Inc. 4-oxo-benzopyran carboxylic acids
DE3469169D1 (en) * 1983-04-21 1988-03-10 Merck Frosst Canada Inc Leukotriene antagonists, their production and use and compositions containing them
US5105017A (en) * 1983-07-18 1992-04-14 Eli Lilly And Company Leukotriene antagonist intermediates
CA1242195A (fr) * 1983-07-18 1988-09-20 David K. Herron Inhibiteurs de leucotrienes
GB8320943D0 (en) * 1983-08-03 1983-09-07 Lilly Industries Ltd Organic compounds
GB8432144D0 (en) * 1984-12-20 1985-01-30 Lilly Industries Ltd Organic compounds
GB8502258D0 (en) * 1985-01-30 1985-02-27 Lilly Industries Ltd Organic compounds
EP0358240B1 (fr) * 1985-04-19 1993-06-09 Smithkline Beecham Corporation Produits intermédiaires pour la préparation d'anagonistes de leukotriène
GB8530222D0 (en) * 1985-12-07 1986-01-15 Lilly Industries Ltd Organic compounds
CA1334200C (fr) * 1987-06-24 1995-01-31 James Simpson Frazee Antagonistes du leucotriene
AU610528B2 (en) * 1987-10-29 1991-05-23 Smithkline Beckman Corporation Leukotriene antagonists

Also Published As

Publication number Publication date
JPH0684344B2 (ja) 1994-10-26
CA2005349A1 (fr) 1990-06-23
PT92724A (pt) 1990-06-29
ATE90940T1 (de) 1993-07-15
EP0375348B1 (fr) 1993-06-23
EP0375348A1 (fr) 1990-06-27
DE68907329D1 (de) 1993-07-29
DK644889D0 (da) 1989-12-19
AU4678789A (en) 1990-06-28
IE894104L (en) 1990-06-23
ZA899721B (en) 1990-09-26
US4954513A (en) 1990-09-04
ES2057153T3 (es) 1994-10-16
DE68907329T2 (de) 1993-09-30
JPH02215764A (ja) 1990-08-28

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Legal Events

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AHB Application shelved due to non-payment