DOP2002000475A - Peptidos que actuan como agonistas del receptor del glp-1 y como antagonistas del receptor del glucagon y sus metodos de uso farmacológico - Google Patents

Peptidos que actuan como agonistas del receptor del glp-1 y como antagonistas del receptor del glucagon y sus metodos de uso farmacológico

Info

Publication number
DOP2002000475A
DOP2002000475A DO2002000475A DO2002000475A DOP2002000475A DO P2002000475 A DOP2002000475 A DO P2002000475A DO 2002000475 A DO2002000475 A DO 2002000475A DO 2002000475 A DO2002000475 A DO 2002000475A DO P2002000475 A DOP2002000475 A DO P2002000475A
Authority
DO
Dominican Republic
Prior art keywords
act
glon
peptides
receptor agonists
methods
Prior art date
Application number
DO2002000475A
Other languages
English (en)
Inventor
Clark Pan
James Whelan
Original Assignee
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Corp filed Critical Bayer Corp
Publication of DOP2002000475A publication Critical patent/DOP2002000475A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La invención provee polipéptidos que actúan como agonistas del receptor del GLP-1 y como antagonistas del receptor del glucagon. Dichos polipéptidos son útiles para el tratamiento de individuos con diabetes tipo 2 u otros trastornos metabólicos.
DO2002000475A 2001-10-05 2002-10-03 Peptidos que actuan como agonistas del receptor del glp-1 y como antagonistas del receptor del glucagon y sus metodos de uso farmacológico DOP2002000475A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32773001P 2001-10-05 2001-10-05

Publications (1)

Publication Number Publication Date
DOP2002000475A true DOP2002000475A (es) 2003-06-30

Family

ID=23277790

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2002000475A DOP2002000475A (es) 2001-10-05 2002-10-03 Peptidos que actuan como agonistas del receptor del glp-1 y como antagonistas del receptor del glucagon y sus metodos de uso farmacológico

Country Status (27)

Country Link
US (6) US7399745B2 (es)
EP (1) EP1436330A4 (es)
JP (1) JP2005508639A (es)
KR (1) KR20050034580A (es)
CN (1) CN1326876C (es)
AR (1) AR036711A1 (es)
BR (1) BR0213132A (es)
CA (1) CA2462462A1 (es)
CO (1) CO5570710A2 (es)
DO (1) DOP2002000475A (es)
EC (2) ECSP024346A (es)
HN (1) HN2002000282A (es)
HR (1) HRP20040327A2 (es)
HU (1) HUP0401797A2 (es)
IL (1) IL160706A0 (es)
MA (1) MA26228A1 (es)
MX (1) MXPA04002140A (es)
MY (1) MY138267A (es)
NO (1) NO20041792L (es)
NZ (1) NZ532685A (es)
PE (1) PE20030850A1 (es)
PL (1) PL368760A1 (es)
RU (1) RU2334761C2 (es)
SG (2) SG149693A1 (es)
UY (1) UY27469A1 (es)
WO (1) WO2003040309A2 (es)
ZA (1) ZA200403322B (es)

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RU2605627C2 (ru) 2010-01-22 2016-12-27 Ново Нордиск Хелс Кеа Аг Гормоны роста с пролонгированной эффективностью in vivo
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Also Published As

Publication number Publication date
ZA200403322B (en) 2005-05-03
MXPA04002140A (es) 2005-03-07
NO20041792L (no) 2004-07-02
UY27469A1 (es) 2003-04-30
BR0213132A (pt) 2004-10-19
ECSP045094A (es) 2004-06-28
RU2334761C2 (ru) 2008-09-27
US20060003417A1 (en) 2006-01-05
CO5570710A2 (es) 2005-10-31
HUP0401797A2 (en) 2006-08-28
PL368760A1 (en) 2005-04-04
HN2002000282A (es) 2002-12-12
WO2003040309A2 (en) 2003-05-15
MY138267A (en) 2009-05-29
CN1326876C (zh) 2007-07-18
MA26228A1 (fr) 2004-07-01
NZ532685A (en) 2006-02-24
CN1564828A (zh) 2005-01-12
CA2462462A1 (en) 2003-05-15
US7488716B2 (en) 2009-02-10
IL160706A0 (en) 2004-08-31
US7488714B2 (en) 2009-02-10
US7488715B2 (en) 2009-02-10
AR036711A1 (es) 2004-09-29
EP1436330A4 (en) 2006-01-18
HK1073117A1 (zh) 2005-09-23
SG158736A1 (en) 2010-02-26
US20060003934A1 (en) 2006-01-05
US20060003418A1 (en) 2006-01-05
KR20050034580A (ko) 2005-04-14
US7399745B2 (en) 2008-07-15
ECSP024346A (es) 2003-05-26
WO2003040309A3 (en) 2003-12-18
US20050288248A1 (en) 2005-12-29
SG149693A1 (en) 2009-02-27
JP2005508639A (ja) 2005-04-07
US7494978B2 (en) 2009-02-24
PE20030850A1 (es) 2003-10-31
RU2004114243A (ru) 2005-05-10
US20060003419A1 (en) 2006-01-05
US20050153890A1 (en) 2005-07-14
HRP20040327A2 (en) 2007-11-30
EP1436330A2 (en) 2004-07-14

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