ECSP056030A - Sistema terapéutico transdérmico estable a los rayos uv - Google Patents
Sistema terapéutico transdérmico estable a los rayos uvInfo
- Publication number
- ECSP056030A ECSP056030A EC2005006030A ECSP056030A ECSP056030A EC SP056030 A ECSP056030 A EC SP056030A EC 2005006030 A EC2005006030 A EC 2005006030A EC SP056030 A ECSP056030 A EC SP056030A EC SP056030 A ECSP056030 A EC SP056030A
- Authority
- EC
- Ecuador
- Prior art keywords
- absorbing agent
- active substance
- therapeutic system
- transdermal therapeutic
- matrix
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 abstract 5
- 239000006096 absorbing agent Substances 0.000 abstract 4
- 239000010410 layer Substances 0.000 abstract 3
- 239000011159 matrix material Substances 0.000 abstract 3
- 239000012790 adhesive layer Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
El invento se refiere a un nuevo sistema terapéutico transdérmico estable a los rayos UV (TTS) que consiste en una capa de base, por lo menos una matriz que contiene sustancia activa y opcionalmente una película despegable y además un agente absorbedor de rayos UV, donde entre la capa de base y la matriz que contiene sustancia activa, que se encuentra más alejada de la superficie de la piel, se prevé por lo menos una capa adhesiva que contiene agente absorbedor de rayos UV y entre la capa adhesiva que contiene el agente absorbedor de rayos UV y la matriz que contiene sustancia activa, que está más alejada de la superficie de la piel, se prevé por lo menos una capa separadora que es impermeable a la sustancia activa e im-permeable al agente absorbedor de rayos UV. El sistema terapéutico transdérmico de la inven-ción posee gran estabilidad y no tiene las desventajas de los TTS que contienen sustancias activas sensibles a la luz tradicionales.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03003888A EP1449526A1 (de) | 2003-02-21 | 2003-02-21 | UV-stabiles transdermales Pflaster |
| EP03004061A EP1452173A1 (de) | 2003-02-25 | 2003-02-25 | UV-stabiles transdermales Pflaster |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP056030A true ECSP056030A (es) | 2006-01-27 |
Family
ID=32910125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2005006030A ECSP056030A (es) | 2003-02-21 | 2005-09-20 | Sistema terapéutico transdérmico estable a los rayos uv |
Country Status (30)
| Country | Link |
|---|---|
| US (3) | US8486443B2 (es) |
| EP (1) | EP1594483B1 (es) |
| JP (1) | JP4528296B2 (es) |
| KR (1) | KR100704825B1 (es) |
| AR (1) | AR043248A1 (es) |
| AT (1) | ATE333271T1 (es) |
| AU (1) | AU2004212675B2 (es) |
| BR (1) | BRPI0407615B8 (es) |
| CA (1) | CA2515918C (es) |
| CR (1) | CR7952A (es) |
| CY (1) | CY1105716T1 (es) |
| DE (1) | DE502004000988D1 (es) |
| DK (1) | DK1594483T3 (es) |
| EA (1) | EA008098B1 (es) |
| EC (1) | ECSP056030A (es) |
| ES (1) | ES2270345T3 (es) |
| HR (1) | HRP20050828B1 (es) |
| IL (1) | IL170295A (es) |
| IS (1) | IS2541B (es) |
| ME (2) | ME00147B (es) |
| MX (1) | MXPA05008778A (es) |
| NO (1) | NO336108B1 (es) |
| NZ (1) | NZ541807A (es) |
| PE (1) | PE20041028A1 (es) |
| PL (1) | PL219030B1 (es) |
| PT (1) | PT1594483E (es) |
| RS (1) | RS50428B (es) |
| SI (1) | SI1594483T1 (es) |
| UY (1) | UY28189A1 (es) |
| WO (1) | WO2004073696A1 (es) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ541807A (en) | 2003-02-21 | 2009-07-31 | Bayer Schering Pharma Ag | UV stable transdermal therapeutic plaster |
| US8668925B2 (en) | 2003-12-12 | 2014-03-11 | Bayer Intellectual Property Gmbh | Transdermal delivery of hormones without the need of penetration enhancers |
| US20070269522A1 (en) * | 2004-08-20 | 2007-11-22 | Wold Chad R | Transdermal Drug Delivery Device with Translucent Protective Film |
| US8962013B2 (en) * | 2005-05-02 | 2015-02-24 | Bayer Intellectual Property Gmbh | Multi-layered transdermal system with triazine UV absorber |
| EP1719504A1 (de) * | 2005-05-02 | 2006-11-08 | Schering AG | Festes transdermales therapeutisches System mit UV-Absorber |
| EP2306929A1 (en) * | 2008-07-14 | 2011-04-13 | SurModics, Inc. | Medical devices and methods for delivery of nucleic acids |
| DE102010040299A1 (de) * | 2010-09-06 | 2012-03-08 | Bayer Schering Pharma Aktiengesellschaft | Transdermale therapeutische Systeme mit kristallisationsinhibierender Schutzfolie (Release Liner) |
| WO2012031999A2 (en) * | 2010-09-06 | 2012-03-15 | Bayer Pharma Aktiengesellschaft | Low-dose transdermal patches with high drug release |
| EP2782584B1 (en) | 2011-11-23 | 2021-06-09 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| AR100562A1 (es) | 2014-05-22 | 2016-10-12 | Therapeuticsmd Inc | Composición farmacéutica de estradiol y progesterona para terapia de reemplazo hormonal |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10835499B2 (en) | 2015-12-30 | 2020-11-17 | Corium, Inc. | Systems and methods for long term transdermal administration |
| KR20180126582A (ko) | 2016-04-01 | 2018-11-27 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 스테로이드 호르몬 약제학적 조성물 |
| WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
| DE102020104907A1 (de) * | 2020-02-25 | 2021-08-26 | Berliner Glas GmbH | Verfahren zur Herstellung eines Bauelements durch atomares Diffusionsbonden |
| KR102989090B1 (ko) | 2024-10-22 | 2026-07-13 | 아주대학교산학협력단 | 마이크로-led 전사 공정용 인터포저 |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5939827A (ja) | 1982-08-27 | 1984-03-05 | Nitto Electric Ind Co Ltd | 医療用外用部材 |
| JPS6069014A (ja) | 1983-09-27 | 1985-04-19 | Nitto Electric Ind Co Ltd | 皮膚疾患治療用貼付剤 |
| US4573996A (en) * | 1984-01-03 | 1986-03-04 | Jonergin, Inc. | Device for the administration of an active agent to the skin or mucosa |
| JPS60166611A (ja) | 1984-02-10 | 1985-08-29 | Nitto Electric Ind Co Ltd | 疾患治療用部材 |
| US5560922A (en) | 1986-05-30 | 1996-10-01 | Rutgers, The State University Of New Jersey | Transdermal absorption dosage unit using a polyacrylate adhesive polymer and process |
| US5023084A (en) | 1986-12-29 | 1991-06-11 | Rutgers, The State University Of New Jersey | Transdermal estrogen/progestin dosage unit, system and process |
| CH674618A5 (es) | 1987-04-02 | 1990-06-29 | Ciba Geigy Ag | |
| US5538736A (en) | 1987-04-28 | 1996-07-23 | Lts Lohmann Therapie-Systeme Gmbh | Active substance-containing plaster for the controlled administration of active substances to the skin |
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| WO1990004397A1 (de) | 1988-10-27 | 1990-05-03 | Schering Aktiengesellschaft Berlin Und Bergkamen | Mittel zur transdermalen applikation enthaltend gestoden |
| DE59107052D1 (de) | 1990-03-30 | 1996-01-25 | Ciba Geigy Ag | Lackzusammensetzungen |
| AU633733B2 (en) | 1990-05-17 | 1993-02-04 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneous preparation containing estradiol |
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| EP0555360A1 (en) | 1990-10-29 | 1993-08-18 | Alza Corporation | Transdermal contraceptive formulations, methods and devices |
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| JP3112707B2 (ja) | 1991-07-25 | 2000-11-27 | 日本電気株式会社 | 監視システム用ポーリング方式 |
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| DE4329242A1 (de) * | 1993-08-26 | 1995-03-02 | Schering Ag | Mittel zur transdermalen Applikation enthaltend Gestodenester |
| DE4336299A1 (de) | 1993-10-25 | 1995-05-11 | Arbo Robotron Medizin Technolo | Gelkörper zur percutanen Verabreichung, insbesondere von Medikamenten |
| DE4403487C2 (de) * | 1994-02-04 | 2003-10-16 | Lohmann Therapie Syst Lts | Arznei-Pflaster mit UV-vernetzbaren Acrylat-Copolymeren |
| DE4405898A1 (de) | 1994-02-18 | 1995-08-24 | Schering Ag | Transdermale therapeutische Systeme enthaltend Sexualsteroide |
| WO1996015776A1 (en) | 1994-11-18 | 1996-05-30 | Hisamitsu Pharmaceutical Co., Inc. | Percutaneously absorbable patch |
| JP3908795B2 (ja) | 1994-11-29 | 2007-04-25 | 久光製薬株式会社 | ケトチフェン含有経皮投与製剤 |
| PL181582B1 (pl) | 1995-06-07 | 2001-08-31 | Ortho Mcneil Pharm Inc | Plaster na skóre do zapobiegania owulacji u kobiety oraz plaster na skóre do przeprowadzania hormonalnej terapii substytucyjnej PL PL PL PL PL PL PL PL |
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| DE19701949A1 (de) | 1997-01-13 | 1998-07-16 | Jenapharm Gmbh | Transdermales therapeutisches System |
| JPH10265371A (ja) | 1997-03-25 | 1998-10-06 | Sekisui Chem Co Ltd | 経皮吸収貼付剤 |
| EP0976405A4 (en) | 1997-04-16 | 2000-12-06 | Hisamitsu Pharmaceutical Co | BASIC COMPOSITION FOR PERCUTANE ABSORPTION AND PERCUTANE ABSORBABLE PREPARATION THAT CONTAINS BASIC COMPOSITION |
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| DE19912623A1 (de) | 1999-03-20 | 2000-09-28 | Lohmann Therapie Syst Lts | Verfahren zur Erhöhung der Stabilität bei Lagerung und/oder Anwendung lichtempfindlicher therapeutischer Systeme oder deren Bestandteile |
| US8173592B1 (en) | 1999-03-31 | 2012-05-08 | Zentaris Ivf Gmbh | Method for a programmed controlled ovarian stimulation protocol |
| EP1197212A4 (en) | 1999-07-01 | 2004-06-02 | Hisamitsu Pharmaceutical Co | ADHESIVE COMPOSITION FOR PERCUTANE ABSORPTION |
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| US20020004065A1 (en) | 2000-01-20 | 2002-01-10 | David Kanios | Compositions and methods to effect the release profile in the transdermal administration of active agents |
| KR100550749B1 (ko) * | 2000-03-17 | 2006-02-08 | 히사미쓰 세이야꾸 가부시키가이샤 | 자외선 차폐성의 첩부제 |
| CA2411950A1 (en) * | 2000-06-13 | 2002-12-09 | Hisamitsu Pharmaceutical Co., Inc. | Patch |
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| US8668925B2 (en) | 2003-12-12 | 2014-03-11 | Bayer Intellectual Property Gmbh | Transdermal delivery of hormones without the need of penetration enhancers |
| UA89766C2 (en) | 2003-12-12 | 2010-03-10 | Байер Шеринг Фарма Акциенгезельшафт | Transdermal delivery system of gestodene |
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| US8962013B2 (en) | 2005-05-02 | 2015-02-24 | Bayer Intellectual Property Gmbh | Multi-layered transdermal system with triazine UV absorber |
| CA2739380C (en) | 2008-10-06 | 2014-12-09 | Mylan Technologies, Inc. | Amorphous rotigotine transdermal system |
-
2004
- 2004-02-04 NZ NZ541807A patent/NZ541807A/xx not_active IP Right Cessation
- 2004-02-04 AU AU2004212675A patent/AU2004212675B2/en not_active Ceased
- 2004-02-04 PT PT04707912T patent/PT1594483E/pt unknown
- 2004-02-04 ME MEP-2008-140A patent/ME00147B/me unknown
- 2004-02-04 EP EP04707912A patent/EP1594483B1/de not_active Expired - Lifetime
- 2004-02-04 SI SI200430077T patent/SI1594483T1/sl unknown
- 2004-02-04 WO PCT/EP2004/001052 patent/WO2004073696A1/de not_active Ceased
- 2004-02-04 RS YUP-2005/0639A patent/RS50428B/sr unknown
- 2004-02-04 BR BRPI0407615A patent/BRPI0407615B8/pt not_active IP Right Cessation
- 2004-02-04 DK DK04707912T patent/DK1594483T3/da active
- 2004-02-04 AT AT04707912T patent/ATE333271T1/de active
- 2004-02-04 DE DE502004000988T patent/DE502004000988D1/de not_active Expired - Lifetime
- 2004-02-04 JP JP2006501740A patent/JP4528296B2/ja not_active Expired - Fee Related
- 2004-02-04 ES ES04707912T patent/ES2270345T3/es not_active Expired - Lifetime
- 2004-02-04 ME MEP-140/08A patent/MEP14008A/xx unknown
- 2004-02-04 CA CA2515918A patent/CA2515918C/en not_active Expired - Lifetime
- 2004-02-04 HR HRP20050828AA patent/HRP20050828B1/hr not_active IP Right Cessation
- 2004-02-04 EA EA200501224A patent/EA008098B1/ru not_active IP Right Cessation
- 2004-02-04 MX MXPA05008778A patent/MXPA05008778A/es active IP Right Grant
- 2004-02-04 KR KR1020057015351A patent/KR100704825B1/ko not_active Expired - Lifetime
- 2004-02-04 PL PL378035A patent/PL219030B1/pl unknown
- 2004-02-04 US US10/545,826 patent/US8486443B2/en not_active Expired - Fee Related
- 2004-02-17 UY UY28189A patent/UY28189A1/es active IP Right Grant
- 2004-02-19 PE PE2004000172A patent/PE20041028A1/es active IP Right Grant
- 2004-02-20 AR ARP040100539A patent/AR043248A1/es not_active Application Discontinuation
-
2005
- 2005-08-16 IL IL170295A patent/IL170295A/en active IP Right Grant
- 2005-08-19 CR CR7952A patent/CR7952A/es unknown
- 2005-09-15 IS IS8031A patent/IS2541B/is unknown
- 2005-09-20 NO NO20054321A patent/NO336108B1/no not_active IP Right Cessation
- 2005-09-20 EC EC2005006030A patent/ECSP056030A/es unknown
-
2006
- 2006-10-19 CY CY20061101501T patent/CY1105716T1/el unknown
-
2013
- 2013-03-15 US US13/835,723 patent/US9095691B2/en not_active Expired - Lifetime
-
2015
- 2015-07-29 US US14/812,431 patent/US20150335658A1/en not_active Abandoned
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