ECSP066497A - Anticuerpos dirigidos a m-csf - Google Patents

Anticuerpos dirigidos a m-csf

Info

Publication number
ECSP066497A
ECSP066497A EC2006006497A ECSP066497A ECSP066497A EC SP066497 A ECSP066497 A EC SP066497A EC 2006006497 A EC2006006497 A EC 2006006497A EC SP066497 A ECSP066497 A EC SP066497A EC SP066497 A ECSP066497 A EC SP066497A
Authority
EC
Ecuador
Prior art keywords
csf
antibodies
relates
human anti
portions
Prior art date
Application number
EC2006006497A
Other languages
English (en)
Inventor
Vahe Bedian
Sirid Aimee Kellermann
Madhav Narasimha Devalaraja
Joseph Edwin S Low
James Leslie Mobley
Ian Foltz
Mary Haak-Frendscho
Original Assignee
Warner Lambert Co
Abgenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33300142&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP066497(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co, Abgenix Inc filed Critical Warner Lambert Co
Publication of ECSP066497A publication Critical patent/ECSP066497A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
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    • G06Q40/00—Finance; Insurance; Tax strategies; Processing of corporate or income taxes
    • G06Q40/04—Trading; Exchange, e.g. stocks, commodities, derivatives or currency exchange
    • G—PHYSICS
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    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q50/00—Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
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    • G06Q50/12—Hotels or restaurants
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

Anticuerpos y porciones que ligan antígeno del mismo que se liga específicamente a un M-CSF preferentemente humano, y que funciona para inhibir al M-CSF. La invención también se refiere a anticuerpos anti-M-CSF humanos y porciones que ligan antígeno de los mismos. La invención también se refiere a anticuerpos que son quiméricos, biespecíficos, derivatizados, anticuerpos de cadena simple o porciones de proteínas de fusión. La invención se refiere también a inmunoglobulinas aislada de cadena pesada y liviana derivadas de anticuerpos anti M-CSF humanos y a moléculas de ácido nucleico que codifican tales inmunoglobulinas. La presente invención también se refiere a formas de fabricas anticuerpos anti-M-CSF humanos a composiciones que comprenden estos anticuerpos y formas para usar estos y sus composiciones. Comprende también formas de terapia con genes que usan moléculas de inmonoglubina que comprenden los anti- M-CSF humanos y a animales y plantas tras génicos que comprenden moléculas de ácido nucleico de la presente invención.
EC2006006497A 2003-09-10 2006-04-10 Anticuerpos dirigidos a m-csf ECSP066497A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50216303P 2003-09-10 2003-09-10

Publications (1)

Publication Number Publication Date
ECSP066497A true ECSP066497A (es) 2006-11-24

Family

ID=33300142

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006497A ECSP066497A (es) 2003-09-10 2006-04-10 Anticuerpos dirigidos a m-csf

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US (8) US7592430B2 (es)
EP (2) EP1670825B9 (es)
JP (6) JP2007528724A (es)
KR (2) KR100899213B1 (es)
CN (2) CN1863817B (es)
AP (1) AP2006003562A0 (es)
AR (1) AR045563A1 (es)
AU (1) AU2004275700B2 (es)
BR (1) BRPI0414269B8 (es)
CA (2) CA2537876C (es)
CR (1) CR8317A (es)
DK (1) DK1670825T3 (es)
EA (1) EA011669B1 (es)
EC (1) ECSP066497A (es)
ES (2) ES2709700T3 (es)
GB (1) GB2405873A (es)
GE (1) GEP20104922B (es)
GT (1) GT200400181A (es)
HN (1) HN2004000356A (es)
HU (1) HUE033708T2 (es)
IL (3) IL174016A (es)
IS (1) IS3021B (es)
MA (1) MA28092A1 (es)
MX (2) MXPA06002825A (es)
MY (1) MY157376A (es)
NL (1) NL1027009C2 (es)
NO (1) NO343557B1 (es)
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