MA28092A1 - Anticorps diriges contre un m-csf - Google Patents

Anticorps diriges contre un m-csf

Info

Publication number
MA28092A1
MA28092A1 MA28927A MA28927A MA28092A1 MA 28092 A1 MA28092 A1 MA 28092A1 MA 28927 A MA28927 A MA 28927A MA 28927 A MA28927 A MA 28927A MA 28092 A1 MA28092 A1 MA 28092A1
Authority
MA
Morocco
Prior art keywords
antibodies
csf
relates
nucleic acid
acid molecules
Prior art date
Application number
MA28927A
Other languages
English (en)
Inventor
Vahe Bedian
Madhav Narasimha Devalaraja
Joseph Edwin Low
James Leslie Mobly
Sirid-Aimee Kellermann
Ian Foltz
Mary Haak-Frendscho
Original Assignee
Warner Lambert Co
Abgenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33300142&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA28092(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co, Abgenix Inc filed Critical Warner Lambert Co
Publication of MA28092A1 publication Critical patent/MA28092A1/fr

Links

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243—Colony Stimulating Factors
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    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
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    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
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    • G06Q40/04—Trading; Exchange, e.g. stocks, commodities, derivatives or currency exchange
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Abstract

La présente invention se rapporte à des anticorps et à leurs parties de liaison à des antigènes qui se lient spécifiquement à un M-CSF, de préférence un M-CSF humain, et qui fonctionnent de manière a inhiber un M-CSF. L'invention se rapporte également à des anticorps anti-M-CSF et à leurs parties de liaison à des antigènes. L'invention se rapporte aussi à des anticorps qui sont des anticorps chimériques, bispécifiques, dérivatisés et à chaîne simple ou des parties de protéines de fusion. L'invention se rapporte également à des immunoglobulines isolées à chaînes lourdes et légères dérivées d'anticorps anti-M-CSF humains et de molécules d'acides nucléiques codant ces immunoglobulines. La présente invention se rapporte également à des procédés d'élaboration d'anticorps anti-M-CSF humains, à des compositions comportant des anticorps et à des procédés d'utilisation de ces anticorps et compositions à des fins diagnostiques et thérapeutiques. L'invention se rapporte également à des méthodes de thérapie génique utilisant des molécules d'acides nucléiques codant les molécules d'immunoglobulines à chaînes lourdes et/ou légères qui comprennent ces anticorps anti-M-CSF humains. L'invention se rapporte en outre à des animaux transgéniques et à des plantes transgéniques comportant les molécules d'acides nucléiques décrites ci-dessus.
MA28927A 2003-09-10 2006-04-10 Anticorps diriges contre un m-csf MA28092A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50216303P 2003-09-10 2003-09-10

Publications (1)

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MA28092A1 true MA28092A1 (fr) 2006-08-01

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MA28927A MA28092A1 (fr) 2003-09-10 2006-04-10 Anticorps diriges contre un m-csf

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US (8) US7592430B2 (fr)
EP (2) EP1670825B9 (fr)
JP (6) JP2007528724A (fr)
KR (2) KR100899213B1 (fr)
CN (2) CN102807617B (fr)
AP (1) AP2006003562A0 (fr)
AR (1) AR045563A1 (fr)
AU (1) AU2004275700B2 (fr)
BR (1) BRPI0414269B8 (fr)
CA (2) CA2885172C (fr)
CR (1) CR8317A (fr)
DK (1) DK1670825T3 (fr)
EA (1) EA011669B1 (fr)
EC (1) ECSP066497A (fr)
ES (2) ES2709700T3 (fr)
GB (1) GB2405873A (fr)
GE (1) GEP20104922B (fr)
GT (1) GT200400181A (fr)
HN (1) HN2004000356A (fr)
HU (1) HUE033708T2 (fr)
IL (3) IL174016A (fr)
IS (1) IS3021B (fr)
MA (1) MA28092A1 (fr)
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JP6319584B2 (ja) 2015-02-27 2018-05-09 京セラドキュメントソリューションズ株式会社 画像形成システム

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