EE03223B1 - Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess - Google Patents

Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess

Info

Publication number
EE03223B1
EE03223B1 EE9600052A EE9600052A EE03223B1 EE 03223 B1 EE03223 B1 EE 03223B1 EE 9600052 A EE9600052 A EE 9600052A EE 9600052 A EE9600052 A EE 9600052A EE 03223 B1 EE03223 B1 EE 03223B1
Authority
EE
Estonia
Prior art keywords
preparation
blood pressure
emulsion containing
pharmaceutical emulsion
dihydropyridine compound
Prior art date
Application number
EE9600052A
Other languages
English (en)
Estonian (et)
Inventor
Hjalmar Andersson Kjell
Kristina Byr�d Eva
Hansson Anna-Carin
Nordlander Margareta
Christer Westerlund Rolf
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE03223B1 publication Critical patent/EE03223B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EE9600052A 1993-11-12 1994-11-03 Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess EE03223B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9303744A SE9303744D0 (sv) 1993-11-12 1993-11-12 Pharmaceutical emulsion
PCT/SE1994/001032 WO1995013066A1 (en) 1993-11-12 1994-11-03 Pharmaceutical emulsion

Publications (1)

Publication Number Publication Date
EE03223B1 true EE03223B1 (et) 1999-10-15

Family

ID=20391731

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600052A EE03223B1 (et) 1993-11-12 1994-11-03 Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess

Country Status (30)

Country Link
US (1) US5739152A (de)
EP (1) EP0727997B1 (de)
JP (1) JP3759951B2 (de)
KR (1) KR100345627B1 (de)
CN (1) CN1072934C (de)
AT (1) ATE213158T1 (de)
AU (1) AU678650B2 (de)
CA (1) CA2176360C (de)
CZ (1) CZ290772B6 (de)
DE (1) DE69429871T2 (de)
DK (1) DK0727997T3 (de)
EE (1) EE03223B1 (de)
EG (1) EG20764A (de)
ES (1) ES2172572T3 (de)
FI (1) FI116999B (de)
HU (1) HU223142B1 (de)
IL (1) IL111345A (de)
IS (1) IS2036B (de)
MY (1) MY121201A (de)
NO (1) NO314877B1 (de)
NZ (1) NZ276197A (de)
PL (1) PL181462B1 (de)
PT (1) PT727997E (de)
RU (1) RU2144358C1 (de)
SA (1) SA94150314B1 (de)
SE (1) SE9303744D0 (de)
SK (1) SK283271B6 (de)
UA (1) UA40633C2 (de)
WO (1) WO1995013066A1 (de)
ZA (1) ZA948180B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
KR100635456B1 (ko) * 1998-05-29 2006-10-18 스키에파마 캐나다 인코포레이티드 열보호화 마이크로입자 조성물 및 그의 말단의 스팀멸균방법
SE9804002D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New manufacturing process
DE10036871A1 (de) 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
KR100915741B1 (ko) 2001-06-15 2009-09-04 코너스톤 파마슈티칼스 표적 조직 및 세포를 치료하기에 유용한 나노입자를함유하는 약제학적 및 진단학적 조성물
CA2811272C (en) 2003-04-08 2016-12-20 Progenics Pharmaceuticals, Inc. Pharmaceutical formulations containing methylnaltrexone
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
EP2565195B1 (de) * 2007-03-29 2015-05-06 Wyeth LLC Peripherer Opioid-Rezeptor sowie Antagonisten und Verwendungen davon
PL2137191T3 (pl) * 2007-03-29 2016-12-30 Antagoniści obwodowego receptora opioidowego i ich zastosowania
JP2010522756A (ja) * 2007-03-29 2010-07-08 プロジェニックス ファーマシューティカルズ，インコーポレーテッド 結晶形およびその使用
AU2008349873B2 (en) 2008-02-06 2014-02-13 Progenics Pharmaceuticals, Inc. Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone
WO2010014727A1 (en) 2008-08-01 2010-02-04 The Medicines Company Pharmaceutical compositions and methods for producing low impurity concentrations of the same
CN102186351A (zh) * 2008-08-01 2011-09-14 医药公司 药物组合物和用于稳定药物组合物的方法
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
JP6081058B2 (ja) * 2009-03-19 2017-02-15 第一三共株式会社 包装により安定保存された固形製剤
CN101780036B (zh) * 2010-03-30 2011-11-16 武汉武药科技有限公司 丁酸氯维地平脂微球注射液及其制备方法
US8658676B2 (en) * 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
PL2627173T5 (pl) 2010-10-12 2019-11-29 Chiesi Farm Spa Formulacje emulsyjne klewidypiny zawierające środki przeciw mikrobom
CN102531998A (zh) * 2010-12-09 2012-07-04 天津药物研究院 α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物
CN102525918A (zh) * 2010-12-30 2012-07-04 天津药物研究院 一种丁酸氯维地平的脂肪乳注射液及其制备工艺
US20120213855A1 (en) * 2011-02-17 2012-08-23 Cima Labs Inc. Dosage forms for weakly ionizable compounds
CA2832066C (en) * 2011-04-01 2023-04-18 The Medicines Company Short-acting dihydropyridines (clevidipine) for use in reducing stroke damage
US10232047B2 (en) 2011-12-20 2019-03-19 Vyome Biosciences Private Limited Topical oil composition for the treatment of fungal infections
KR102299073B1 (ko) 2012-10-26 2021-09-09 치에시 파마슈티시 에스.피.아. 심부전에서 혈압을 조절하고 호흡곤란을 감소시키는 방법
CN103110580B (zh) * 2013-02-20 2014-09-17 北京德立福瑞医药科技有限公司 丁酸氯维地平注射剂
US20160058775A1 (en) * 2013-04-12 2016-03-03 Vyome Biosciences Pvt. Ltd. Composition and formulation of antimicrobial agents, processes thereof and methods for treating microbial infections
CA2947486C (en) 2014-05-19 2023-09-26 The Medicines Company Clevidipine nanoparticles and pharmaceutical compositions thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315805A1 (de) * 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4217842A1 (de) * 1992-05-29 1993-12-02 Dietl Hans Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
FI961999L (fi) 1996-05-10
NO961898D0 (no) 1996-05-10
CZ290772B6 (cs) 2002-10-16
NO314877B1 (no) 2003-06-10
HU9601268D0 (en) 1996-07-29
KR100345627B1 (ko) 2003-03-15
AU1037195A (en) 1995-05-29
EP0727997A1 (de) 1996-08-28
SA94150314B1 (ar) 2005-06-14
SE9303744D0 (sv) 1993-11-12
UA40633C2 (uk) 2001-08-15
PT727997E (pt) 2002-07-31
US5739152A (en) 1998-04-14
DE69429871D1 (de) 2002-03-21
NO961898L (no) 1996-06-25
CA2176360A1 (en) 1995-05-18
CA2176360C (en) 2005-08-23
IS2036B (is) 2005-08-15
NZ276197A (en) 1997-04-24
WO1995013066A1 (en) 1995-05-18
HK1013261A1 (en) 1999-08-20
ES2172572T3 (es) 2002-10-01
IL111345A0 (en) 1994-12-29
JPH09505045A (ja) 1997-05-20
ATE213158T1 (de) 2002-02-15
CN1136774A (zh) 1996-11-27
PL314263A1 (en) 1996-09-02
IS4224A (is) 1995-05-13
CZ133896A3 (en) 1996-09-11
RU2144358C1 (ru) 2000-01-20
ZA948180B (en) 1995-05-12
DE69429871T2 (de) 2002-08-22
SK59796A3 (en) 1996-12-04
HUT74474A (en) 1996-12-30
SK283271B6 (sk) 2003-04-01
DK0727997T3 (da) 2002-04-22
PL181462B1 (pl) 2001-07-31
EG20764A (en) 2000-01-31
HU223142B1 (hu) 2004-03-29
IL111345A (en) 2000-08-31
EP0727997B1 (de) 2002-02-13
JP3759951B2 (ja) 2006-03-29
FI961999A0 (fi) 1996-05-10
MY121201A (en) 2006-01-28
AU678650B2 (en) 1997-06-05
FI116999B (fi) 2006-05-15
CN1072934C (zh) 2001-10-17

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