IS2036B - Lyfjablanda á formi dropalausnar sem inniheldur skammvirkt kalsíummótlyf af tvíhýdrópýridíngerð semvinna gegn háþrýstingi - Google Patents

Lyfjablanda á formi dropalausnar sem inniheldur skammvirkt kalsíummótlyf af tvíhýdrópýridíngerð semvinna gegn háþrýstingi

Info

Publication number: IS2036B
Authority: IS; Iceland
Prior art keywords: short; antidote; dihydropyridine; antidepressant; solution containing
Prior art date: 1993-11-12

Application number

IS4224A

Other languages

English (en)

Other versions

IS4224A (is

Inventor

Hjalmar Andersson Kjell

Christina Byröd Eva

Hansson Anna-Carin

Nordlander Margareta

Christer Westerlund Rolf

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-11-12

Filing date

1994-10-21

Publication date

2005-08-15

1994-10-21 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

1995-05-13 Publication of IS4224A publication Critical patent/IS4224A/is

2005-08-15 Publication of IS2036B publication Critical patent/IS2036B/is

Links

YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical compound C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title 1
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title 1
230000001430 anti-depressive effect Effects 0.000 title 1
239000000935 antidepressant agent Substances 0.000 title 1
229940005513 antidepressants Drugs 0.000 title 1
239000000729 antidote Substances 0.000 title 1
229910052791 calcium Inorganic materials 0.000 title 1
239000011575 calcium Substances 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
-1 dihydropyridine compound Chemical class 0.000 abstract 1
239000003995 emulsifying agent Substances 0.000 abstract 1
238000001990 intravenous administration Methods 0.000 abstract 1
150000002632 lipids Chemical class 0.000 abstract 1
239000008251 pharmaceutical emulsion Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Detergent Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

IS4224A 1993-11-12 1994-10-21 Lyfjablanda á formi dropalausnar sem inniheldur skammvirkt kalsíummótlyf af tvíhýdrópýridíngerð semvinna gegn háþrýstingi IS2036B (is)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9303744A SE9303744D0 (sv)	1993-11-12	1993-11-12	Pharmaceutical emulsion

Publications (2)

Publication Number	Publication Date
IS4224A IS4224A (is)	1995-05-13
IS2036B true IS2036B (is)	2005-08-15

Family

ID=20391731

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS4224A IS2036B (is)	1993-11-12	1994-10-21	Lyfjablanda á formi dropalausnar sem inniheldur skammvirkt kalsíummótlyf af tvíhýdrópýridíngerð semvinna gegn háþrýstingi

Country Status (30)

Country	Link
US (1)	US5739152A (is)
EP (1)	EP0727997B1 (is)
JP (1)	JP3759951B2 (is)
KR (1)	KR100345627B1 (is)
CN (1)	CN1072934C (is)
AT (1)	ATE213158T1 (is)
AU (1)	AU678650B2 (is)
CA (1)	CA2176360C (is)
CZ (1)	CZ290772B6 (is)
DE (1)	DE69429871T2 (is)
DK (1)	DK0727997T3 (is)
EE (1)	EE03223B1 (is)
EG (1)	EG20764A (is)
ES (1)	ES2172572T3 (is)
FI (1)	FI116999B (is)
HU (1)	HU223142B1 (is)
IL (1)	IL111345A (is)
IS (1)	IS2036B (is)
MY (1)	MY121201A (is)
NO (1)	NO314877B1 (is)
NZ (1)	NZ276197A (is)
PL (1)	PL181462B1 (is)
PT (1)	PT727997E (is)
RU (1)	RU2144358C1 (is)
SA (1)	SA94150314B1 (is)
SE (1)	SE9303744D0 (is)
SK (1)	SK283271B6 (is)
UA (1)	UA40633C2 (is)
WO (1)	WO1995013066A1 (is)
ZA (1)	ZA948180B (is)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030158220A1 (en) *	1997-11-03	2003-08-21	Foss Joseph F.	Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
ES2216517T3 (es) *	1998-05-29	2004-10-16	Skyepharma Canada Inc.	Composiciones de microcapsulas termoprotegidas y procedimiento para su esterilizacion terminal con vapor.
SE9804002D0 (sv) *	1998-11-23	1998-11-23	Astra Ab	New manufacturing process
DE10036871A1 (de)	2000-07-28	2002-02-14	Pharmasol Gmbh	Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
WO2002102311A2 (en)	2001-06-15	2002-12-27	Cornerstone Pharmaceuticals	Nanoparticles for treating targeted tissues and cells
ES2528669T3 (es) *	2003-04-08	2015-02-11	Progenics Pharmaceuticals, Inc.	Formulaciones farmacéuticas que contienen metilnaltrexona
AR057325A1 (es) *	2005-05-25	2007-11-28	Progenics Pharm Inc	Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) *	2005-05-25	2007-11-14	Progenics Pharm Inc	SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
TWI489984B (zh)	2006-08-04	2015-07-01	Wyeth Corp	用於非經腸道傳輸化合物之配方及其用途
TW200817048A (en) *	2006-09-08	2008-04-16	Wyeth Corp	Dry powder compound formulations and uses thereof
PE20090700A1 (es) *	2007-03-29	2009-07-13	Progenics Pharm Inc	Compuestos heterociclicos como antagonistas del receptor opioide periferico
BRPI0809579B8 (pt)	2007-03-29	2021-05-25	Progenics Pharm Inc	formas cristalinas e seus usos
PL2139890T3 (pl) *	2007-03-29	2014-11-28	Wyeth Llc	Antagoniści obwodowych receptorów opioidowych i ich zastosowania
WO2009099411A1 (en)	2008-02-06	2009-08-13	Progenics Pharmaceuticals, Inc.	Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
EP2320740B1 (en) *	2008-08-01	2014-03-26	The Medicines Company	Pharmaceutical compositions of clevidipine and methods for producing low impurity concentrations of the same
MX2011001241A (es) *	2008-08-01	2011-08-03	Medicines Co	Composiciones farmaceuticas y metodos para estabilizar las mismas.
CA2676881C (en)	2008-09-30	2017-04-25	Wyeth	Peripheral opioid receptor antagonists and uses thereof
US8993625B2 (en)	2009-03-11	2015-03-31	Stable Solutions Llc	Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
US9034389B2 (en) *	2009-03-11	2015-05-19	Stable Solutions Llc	Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
JP6081058B2 (ja) *	2009-03-19	2017-02-15	第一三共株式会社	包装により安定保存された固形製剤
CN101780036B (zh) *	2010-03-30	2011-11-16	武汉武药科技有限公司	丁酸氯维地平脂微球注射液及其制备方法
US8658676B2 (en)	2010-10-12	2014-02-25	The Medicines Company	Clevidipine emulsion formulations containing antimicrobial agents
BR112013008601B1 (pt)	2010-10-12	2020-03-31	Chiesi Farmaceutici S.P.A.	Formulações de emulsão de clevidipina contendo agentes antimicrobianos
CN102531998A (zh) *	2010-12-09	2012-07-04	天津药物研究院	α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物
CN102525918A (zh) *	2010-12-30	2012-07-04	天津药物研究院	一种丁酸氯维地平的脂肪乳注射液及其制备工艺
US20120213855A1 (en) *	2011-02-17	2012-08-23	Cima Labs Inc.	Dosage forms for weakly ionizable compounds
BR112013025368A8 (pt) *	2011-04-01	2018-06-12	The Medicines Co	Medicamento, método para preparar um medicamento útil para reduzir danos por derrame em um sujeito com derrame, método para preparar um medicamento útil para reduzir a pressão sanguínea e reduzir danos por derrame em um sujeito com derrame
EP2793833B1 (en)	2011-12-20	2020-06-24	Vyome Therapeutics Limited	Topical oil composition for the treatment of fungal infections
CN110840890A (zh)	2012-10-26	2020-02-28	凯西制药公司	用于在心力衰竭中控制血压和减轻呼吸困难的方法
CN103110580B (zh) *	2013-02-20	2014-09-17	北京德立福瑞医药科技有限公司	丁酸氯维地平注射剂
CN105263525A (zh) *	2013-04-12	2016-01-20	维奥姆生物科学有限公司	抗微生物剂的组合物和制剂、它们的方法以及用于治疗微生物感染的方法
MX385243B (es)	2014-05-19	2025-03-14	The Medicines Co	Nanoparticulas de clevidipina y composiciones farmaceuticas que las contienen.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3315805A1 (de) *	1983-04-30	1984-11-08	Bayer Ag, 5090 Leverkusen	Wirkstoffzubereitungen
DE3339236A1 (de) *	1983-10-28	1985-05-09	Bayer Ag	Arzneimittelzubereitung
DE3515335C2 (de) *	1985-04-27	1995-01-26	Bayer Ag	Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4217842A1 (de) *	1992-05-29	1993-12-02	Dietl Hans	Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung

1993
- 1993-11-12 SE SE9303744A patent/SE9303744D0/xx unknown
1994
- 1994-10-18 ZA ZA948180A patent/ZA948180B/xx unknown
- 1994-10-20 IL IL11134594A patent/IL111345A/xx not_active IP Right Cessation
- 1994-10-21 IS IS4224A patent/IS2036B/is unknown
- 1994-11-03 ES ES95900965T patent/ES2172572T3/es not_active Expired - Lifetime
- 1994-11-03 RU RU96112112A patent/RU2144358C1/ru active
- 1994-11-03 KR KR1019960702485A patent/KR100345627B1/ko not_active Expired - Lifetime
- 1994-11-03 CN CN94194111A patent/CN1072934C/zh not_active Expired - Lifetime
- 1994-11-03 CA CA002176360A patent/CA2176360C/en not_active Expired - Lifetime
- 1994-11-03 EP EP95900965A patent/EP0727997B1/en not_active Expired - Lifetime
- 1994-11-03 UA UA96051803A patent/UA40633C2/uk unknown
- 1994-11-03 US US08/364,953 patent/US5739152A/en not_active Expired - Lifetime
- 1994-11-03 PT PT95900965T patent/PT727997E/pt unknown
- 1994-11-03 WO PCT/SE1994/001032 patent/WO1995013066A1/en not_active Ceased
- 1994-11-03 JP JP51375695A patent/JP3759951B2/ja not_active Expired - Lifetime
- 1994-11-03 SK SK597-96A patent/SK283271B6/sk not_active IP Right Cessation
- 1994-11-03 EE EE9600052A patent/EE03223B1/xx unknown
- 1994-11-03 HU HU9601268A patent/HU223142B1/hu active IP Right Grant
- 1994-11-03 DK DK95900965T patent/DK0727997T3/da active
- 1994-11-03 CZ CZ19961338A patent/CZ290772B6/cs not_active IP Right Cessation
- 1994-11-03 DE DE69429871T patent/DE69429871T2/de not_active Expired - Lifetime
- 1994-11-03 AT AT95900965T patent/ATE213158T1/de active
- 1994-11-03 AU AU10371/95A patent/AU678650B2/en not_active Expired
- 1994-11-03 NZ NZ276197A patent/NZ276197A/en not_active IP Right Cessation
- 1994-11-03 PL PL94314263A patent/PL181462B1/pl unknown
- 1994-11-09 EG EG71094A patent/EG20764A/xx active
- 1994-11-14 MY MYPI94003029A patent/MY121201A/en unknown
- 1994-11-23 SA SA94150314A patent/SA94150314B1/ar unknown
1996
- 1996-05-10 FI FI961999A patent/FI116999B/fi not_active IP Right Cessation
- 1996-05-10 NO NO19961898A patent/NO314877B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP3759951B2 (ja)	2006-03-29
ES2172572T3 (es)	2002-10-01
HK1013261A1 (en)	1999-08-20
HU9601268D0 (en)	1996-07-29
US5739152A (en)	1998-04-14
NZ276197A (en)	1997-04-24
CN1072934C (zh)	2001-10-17
AU1037195A (en)	1995-05-29
MY121201A (en)	2006-01-28
CZ133896A3 (en)	1996-09-11
IL111345A0 (en)	1994-12-29
JPH09505045A (ja)	1997-05-20
EE03223B1 (et)	1999-10-15
ZA948180B (en)	1995-05-12
CA2176360C (en)	2005-08-23
CA2176360A1 (en)	1995-05-18
SK59796A3 (en)	1996-12-04
UA40633C2 (uk)	2001-08-15
PL181462B1 (pl)	2001-07-31
NO961898D0 (no)	1996-05-10
ATE213158T1 (de)	2002-02-15
FI961999A0 (fi)	1996-05-10
IL111345A (en)	2000-08-31
DE69429871D1 (de)	2002-03-21
NO314877B1 (no)	2003-06-10
EG20764A (en)	2000-01-31
EP0727997A1 (en)	1996-08-28
SA94150314B1 (ar)	2005-06-14
CN1136774A (zh)	1996-11-27
FI116999B (fi)	2006-05-15
WO1995013066A1 (en)	1995-05-18
DK0727997T3 (da)	2002-04-22
IS4224A (is)	1995-05-13
KR100345627B1 (ko)	2003-03-15
PL314263A1 (en)	1996-09-02
PT727997E (pt)	2002-07-31
RU2144358C1 (ru)	2000-01-20
EP0727997B1 (en)	2002-02-13
AU678650B2 (en)	1997-06-05
SE9303744D0 (sv)	1993-11-12
FI961999L (fi)	1996-05-10
CZ290772B6 (cs)	2002-10-16
HUT74474A (en)	1996-12-30
HU223142B1 (hu)	2004-03-29
SK283271B6 (sk)	2003-04-01
DE69429871T2 (de)	2002-08-22
NO961898L (no)	1996-06-25

Publication	Publication Date	Title
IS2036B (is)	2005-08-15	Lyfjablanda á formi dropalausnar sem inniheldur skammvirkt kalsíummótlyf af tvíhýdrópýridíngerð semvinna gegn háþrýstingi
DZ1794A1 (fr)	2002-02-17	Nouvelle formule pharmaceutique.
ATE168268T1 (de)	1998-08-15	Behandlung von menschlichen retrovirus- infektionen mit 2',3'-dideoxyinosin
FI924553A0 (fi)	1992-10-08	Tiofensulfonamider anvaendbara som kolanhydrasinhibitorer
DE69331409D1 (de)	2002-02-07	Oral 1alpha-hydroxyprevitamin d
BG103552A (bg)	2000-04-28	Терапевтични средства
ES2102475T3 (es)	1997-08-01	Nuevas alquil-amidas heterociclicas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
NO870560L (no)	1987-08-14	Nytt farmasoeytisk preparat.
ATE213633T1 (de)	2002-03-15	Lamotrigin haltiges arzneimittel
TR200101163T2 (tr)	2001-08-21	Safra suyu ikameli fenil-alkenoilguanidinler, üretim yöntemleri, kullanımları
EP0683668A4 (en)	1997-12-29	PREPARATIONS AND METHODS FOR TRANSDERMAL DRUG ADMINISTRATION.
PT99435A (pt)	1992-12-31	Processo para a preparacao de derivados de amino-sulfonil-ureia e de composicoes farmaceuticas que os contem
GR890100833A (en)	1991-03-15	Process for the preparation of a compound with gastric inhibitopy effect
DK0866711T3 (da)	2006-11-27	Anvendelse af 6-methyl-5-oxo-3-thiomorpholinylcarbonyl-L-histidyl-L-prolinamid til fremstilling af et farmaceutisk præparat til modvirkning af sövnapnö
KR910007523A (ko)	1991-05-30	과콜레스테린혈증, 과지방혈증 및 혈전색전증 질병 치료용 토코트리엔올
KR960703593A (ko)	1996-08-31	(R)-암로디핀에 의한 평활근 세포 이동의 억제 (Inhibition of Smooth Muscle Cell Migration by (R)-Amlodipine)
DK0706395T3 (da)	2002-07-22	Lægemiddel med analgetisk effekt med minimal bevægelsesblokade
DK0808306T3 (da)	2000-03-06	Hidtil ukendte pyridin- eller pyridazinderivater, fremgangsmåder til fremstilling deraf og lægemidler indeholdende disse fo
KR960700053A (ko)	1996-01-19	방사선회복제로서 리루졸의 이용(application of riluzole as a radiorestorer)