ES2172572T3 - Emulsion farmaceutica. - Google Patents

Emulsion farmaceutica.

Info

Publication number
ES2172572T3
ES2172572T3 ES95900965T ES95900965T ES2172572T3 ES 2172572 T3 ES2172572 T3 ES 2172572T3 ES 95900965 T ES95900965 T ES 95900965T ES 95900965 T ES95900965 T ES 95900965T ES 2172572 T3 ES2172572 T3 ES 2172572T3
Authority
ES
Spain
Prior art keywords
pharmaceutical emulsion
emulsion
pharmaceutical
dihydropiridine
emulsor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95900965T
Other languages
English (en)
Inventor
Kjell Hjalmar Andersson
Eva Kristina Byrod
Anna-Carin Hansson
Margareta Nordlander
Rolf Christer Westerlund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Application granted granted Critical
Publication of ES2172572T3 publication Critical patent/ES2172572T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA EMULSION FARMACEUTICA QUE CONTIENE (A) UN COMPUESTO DE DIHIDROPIRIDINA DE ACTUACION RAPIDA; (B) UNA FASE LIPIDA; (C) UN EMULSOR; Y (D) AGUA O UN TAMPON, AL USO DE Y AL PROCEDIMIENTO PARA LA PREPARACION DE LA EMULSION.
ES95900965T 1993-11-12 1994-11-03 Emulsion farmaceutica. Expired - Lifetime ES2172572T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9303744A SE9303744D0 (sv) 1993-11-12 1993-11-12 Pharmaceutical emulsion

Publications (1)

Publication Number Publication Date
ES2172572T3 true ES2172572T3 (es) 2002-10-01

Family

ID=20391731

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95900965T Expired - Lifetime ES2172572T3 (es) 1993-11-12 1994-11-03 Emulsion farmaceutica.

Country Status (30)

Country Link
US (1) US5739152A (es)
EP (1) EP0727997B1 (es)
JP (1) JP3759951B2 (es)
KR (1) KR100345627B1 (es)
CN (1) CN1072934C (es)
AT (1) ATE213158T1 (es)
AU (1) AU678650B2 (es)
CA (1) CA2176360C (es)
CZ (1) CZ290772B6 (es)
DE (1) DE69429871T2 (es)
DK (1) DK0727997T3 (es)
EE (1) EE03223B1 (es)
EG (1) EG20764A (es)
ES (1) ES2172572T3 (es)
FI (1) FI116999B (es)
HU (1) HU223142B1 (es)
IL (1) IL111345A (es)
IS (1) IS2036B (es)
MY (1) MY121201A (es)
NO (1) NO314877B1 (es)
NZ (1) NZ276197A (es)
PL (1) PL181462B1 (es)
PT (1) PT727997E (es)
RU (1) RU2144358C1 (es)
SA (1) SA94150314B1 (es)
SE (1) SE9303744D0 (es)
SK (1) SK283271B6 (es)
UA (1) UA40633C2 (es)
WO (1) WO1995013066A1 (es)
ZA (1) ZA948180B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
EP1079808B1 (en) * 1998-05-29 2004-02-11 Skyepharma Canada Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
SE9804002D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New manufacturing process
DE10036871A1 (de) 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
JP2005500293A (ja) 2001-06-15 2005-01-06 コーナーストーン ファーマシューティカルズ 標的とする組織及び細胞の治療に有用なナノ粒子を含む薬剤組成物及び診断のための組成物
HRP20150037T4 (hr) * 2003-04-08 2022-09-02 Progenics Pharmaceuticals, Inc. Farmaceutske formulacije koje sadrže metilnaltrekson
AR057035A1 (es) * 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
US8546418B2 (en) * 2007-03-29 2013-10-01 Progenics Pharmaceuticals, Inc. Peripheral opioid receptor antagonists and uses thereof
CA2682129A1 (en) 2007-03-29 2008-10-09 Progenics Pharmaceuticals, Inc. Crystal forms and uses thereof
PT2139890E (pt) 2007-03-29 2014-09-03 Wyeth Llc Antagonistas do receptor opióide periférico e respectivas utilizações
EP2240489A1 (en) * 2008-02-06 2010-10-20 Progenics Pharmaceuticals, Inc. Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone
LT2320739T (lt) 2008-08-01 2020-01-27 Chiesi Farmaceutici S.P.A. Farmacinės kompozicijos ir jų stabilizavimo būdai
MX2011001240A (es) * 2008-08-01 2011-08-12 Medicines Co Composiciones farmaceuticas y metodos para producir concentraciones de baja impureza de las mismas.
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
US9034389B2 (en) 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
JP6081058B2 (ja) * 2009-03-19 2017-02-15 第一三共株式会社 包装により安定保存された固形製剤
CN101780036B (zh) * 2010-03-30 2011-11-16 武汉武药科技有限公司 丁酸氯维地平脂微球注射液及其制备方法
US8658676B2 (en) * 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
WO2012051116A1 (en) 2010-10-12 2012-04-19 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
CN102531998A (zh) * 2010-12-09 2012-07-04 天津药物研究院 α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物
CN102525918A (zh) * 2010-12-30 2012-07-04 天津药物研究院 一种丁酸氯维地平的脂肪乳注射液及其制备工艺
US20120213855A1 (en) * 2011-02-17 2012-08-23 Cima Labs Inc. Dosage forms for weakly ionizable compounds
CA2832066C (en) 2011-04-01 2023-04-18 The Medicines Company Short-acting dihydropyridines (clevidipine) for use in reducing stroke damage
CN104105472A (zh) 2011-12-20 2014-10-15 维奥姆生物科学有限公司 用于治疗真菌感染的局部油组合物
EA030354B1 (ru) 2012-10-26 2018-07-31 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Способ уменьшения диспноэ у пациента с острой сердечной недостаточностью
CN103110580B (zh) * 2013-02-20 2014-09-17 北京德立福瑞医药科技有限公司 丁酸氯维地平注射剂
EA201591954A1 (ru) * 2013-04-12 2016-04-29 Вайом Байосайнсиз Пвт. Лтд. Композиция и состав противомикробных средств, способы их получения и способы лечения микробных инфекций
WO2015179334A1 (en) 2014-05-19 2015-11-26 The Medicines Company Clevidipine nanoparticles and pharmaceutical compositions thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315805A1 (de) * 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4217842A1 (de) * 1992-05-29 1993-12-02 Dietl Hans Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
SE9303744D0 (sv) 1993-11-12
DE69429871D1 (de) 2002-03-21
NO961898D0 (no) 1996-05-10
PL314263A1 (en) 1996-09-02
CZ290772B6 (cs) 2002-10-16
AU1037195A (en) 1995-05-29
IL111345A (en) 2000-08-31
CZ133896A3 (en) 1996-09-11
IS2036B (is) 2005-08-15
KR100345627B1 (ko) 2003-03-15
FI961999A0 (fi) 1996-05-10
US5739152A (en) 1998-04-14
NO961898L (no) 1996-06-25
MY121201A (en) 2006-01-28
CN1072934C (zh) 2001-10-17
SA94150314B1 (ar) 2005-06-14
CA2176360C (en) 2005-08-23
IL111345A0 (en) 1994-12-29
CN1136774A (zh) 1996-11-27
HU9601268D0 (en) 1996-07-29
WO1995013066A1 (en) 1995-05-18
ATE213158T1 (de) 2002-02-15
HUT74474A (en) 1996-12-30
FI116999B (fi) 2006-05-15
EE03223B1 (et) 1999-10-15
EG20764A (en) 2000-01-31
JP3759951B2 (ja) 2006-03-29
CA2176360A1 (en) 1995-05-18
RU2144358C1 (ru) 2000-01-20
HU223142B1 (hu) 2004-03-29
UA40633C2 (uk) 2001-08-15
AU678650B2 (en) 1997-06-05
EP0727997B1 (en) 2002-02-13
PT727997E (pt) 2002-07-31
ZA948180B (en) 1995-05-12
SK59796A3 (en) 1996-12-04
DK0727997T3 (da) 2002-04-22
NO314877B1 (no) 2003-06-10
DE69429871T2 (de) 2002-08-22
PL181462B1 (pl) 2001-07-31
EP0727997A1 (en) 1996-08-28
JPH09505045A (ja) 1997-05-20
HK1013261A1 (en) 1999-08-20
FI961999L (fi) 1996-05-10
NZ276197A (en) 1997-04-24
IS4224A (is) 1995-05-13
SK283271B6 (sk) 2003-04-01

Similar Documents

Publication Publication Date Title
MX9204268A (es) Una composicion para la liberacion prolongada y controlada de substancias medicamentosas y un proceso para preparar la misma.
AR027162A1 (es) Compuestos de 2-fenil-3-fenoxilo-feniltio-benzotiofeno, sales farmaceuticamente aceptables de los mismos y composiciones farmaceuticas que los contienen
MX9205432A (es) Compuestos inhibidores de la biosintesis de leucotrienos y composicion farmaceutica que los contiene.
MX9201082A (es) Procedimiento para la preparacion de una composicion farmaceutica que comprende gases propelentes libres de cloro.
ES557835A0 (es) Un procedimiento para preparar una formulacion farmaceutica que contiene 3'-azido-3'-desoxitimidina o uno de sus derivados farmaceuticamente aceptables.
MX9202619A (es) Derivados de oxa tiolano cristalino, metodo para su preparacion y formulacion farmaceutica que los contiene.
ES2100151T3 (es) Nuevos derivados de benzopirano, procedimientos para su preparacion y su uso y composiciones que contienen los compuestos.
ES2177584T3 (es) Composicion de prostaglandinas transdermica.
ES547738A0 (es) Un procedimiento para la preparacion de una composicion terapeutica que contiene un fosfato de dialquilo.
DK155389A (da) Praeparater indeholdende thymol, herunder mundhygiejnepraeparater, til maskering af smagen af thymol
MX9204140A (es) Nuevos derivados de analogos de taxol, procedimiento para su preparacion y composicion farmaceutica que los contienen.
ES2144151T3 (es) Benzotiazepinas hipolipidemicas.
NO964639L (no) Substituerte sulfonimidamider, fremgangsmåte for fremstilling derav, deres anvendelse som medikament eller diagnostikum samt medikament inneholdende forbindelsen
ES2086771T3 (es) Composicion dermatologica y/o cosmetologica que contiene retinoides.
AR012125A1 (es) UNA SAL DE UN COMPUESTO DERIVADO DEL ÁCIDO NAFTIRIDINA CARBOXíLICO , SU USO PARA LA FABRICACIoN DE UN MEDICAMENTO , PROCEDIMIENTO PARA PREPARARLA Y UNA COMPOSICIoN FARMACÉUTICA QUE LO COMPRENDE
ES2183180T3 (es) Nuevos derivados de guanidina, procedimientos para su preparacion y su uso como medicamento.
SE8904298D0 (sv) New compounds
BR9609327A (pt) Novos derivados de oxazolidinona processos para sua preparação e agentes farmacêuticos que contêm estes compostos
AR002157A1 (es) Uso de una dosis inmunizante eficaz de esporozoitos o merozoitos de eimeria vivos, o una mezcla de los mismos
CY1105465T1 (el) Μορφη δοσολογιας πepιλαμβανουσα υγρο σκευασμα
MX9201058A (es) Derivados ciclicos de cetal, procedimiento para supreparacion y composicion farmaceutica que los contiene.
MX9204237A (es) Nuevos derivados de ciclohexano y tetrahidropiran, procedimiento para su preparacion y composicion antifungal que los contiene.
ES2105605T3 (es) Antagonistas de taquiquinina, su preparacion y utilizacion en formulaciones farmaceuticas.
ES554747A0 (es) Un procedimiento para la preparacion de una composicion entonadora electrofotografica.
MX6424A (es) Derivados de tripeptidos, procedimientos para la preparacion de derivados de tripeptidos y composiciones que los contienen.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 727997

Country of ref document: ES