EE03223B1 - Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess - Google Patents

Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess

Info

Publication number
EE03223B1
EE03223B1 EE9600052A EE9600052A EE03223B1 EE 03223 B1 EE03223 B1 EE 03223B1 EE 9600052 A EE9600052 A EE 9600052A EE 9600052 A EE9600052 A EE 9600052A EE 03223 B1 EE03223 B1 EE 03223B1
Authority
EE
Estonia
Prior art keywords
preparation
blood pressure
emulsion containing
pharmaceutical emulsion
dihydropyridine compound
Prior art date
Application number
EE9600052A
Other languages
English (en)
Estonian (et)
Inventor
Hjalmar Andersson Kjell
Kristina Byr�d Eva
Hansson Anna-Carin
Nordlander Margareta
Christer Westerlund Rolf
Original Assignee
Astra Aktiebolag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Aktiebolag filed Critical Astra Aktiebolag
Publication of EE03223B1 publication Critical patent/EE03223B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
EE9600052A 1993-11-12 1994-11-03 Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess EE03223B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9303744A SE9303744D0 (sv) 1993-11-12 1993-11-12 Pharmaceutical emulsion
PCT/SE1994/001032 WO1995013066A1 (en) 1993-11-12 1994-11-03 Pharmaceutical emulsion

Publications (1)

Publication Number Publication Date
EE03223B1 true EE03223B1 (et) 1999-10-15

Family

ID=20391731

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9600052A EE03223B1 (et) 1993-11-12 1994-11-03 Kiiretoimelist dihüdropüridiinühendit sisaldav farmatseutiline emulsioon vererõhu alandamiseks ja selle valmistamise protsess

Country Status (30)

Country Link
US (1) US5739152A (pl)
EP (1) EP0727997B1 (pl)
JP (1) JP3759951B2 (pl)
KR (1) KR100345627B1 (pl)
CN (1) CN1072934C (pl)
AT (1) ATE213158T1 (pl)
AU (1) AU678650B2 (pl)
CA (1) CA2176360C (pl)
CZ (1) CZ290772B6 (pl)
DE (1) DE69429871T2 (pl)
DK (1) DK0727997T3 (pl)
EE (1) EE03223B1 (pl)
EG (1) EG20764A (pl)
ES (1) ES2172572T3 (pl)
FI (1) FI116999B (pl)
HU (1) HU223142B1 (pl)
IL (1) IL111345A (pl)
IS (1) IS2036B (pl)
MY (1) MY121201A (pl)
NO (1) NO314877B1 (pl)
NZ (1) NZ276197A (pl)
PL (1) PL181462B1 (pl)
PT (1) PT727997E (pl)
RU (1) RU2144358C1 (pl)
SA (1) SA94150314B1 (pl)
SE (1) SE9303744D0 (pl)
SK (1) SK283271B6 (pl)
UA (1) UA40633C2 (pl)
WO (1) WO1995013066A1 (pl)
ZA (1) ZA948180B (pl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
AU764001B2 (en) * 1998-05-29 2003-08-07 Skyepharma Canada Inc. Thermoprotected microparticle compositions and process for terminal steam sterilization thereof
SE9804002D0 (sv) * 1998-11-23 1998-11-23 Astra Ab New manufacturing process
DE10036871A1 (de) 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
WO2002102311A2 (en) 2001-06-15 2002-12-27 Cornerstone Pharmaceuticals Nanoparticles for treating targeted tissues and cells
PL2368554T3 (pl) * 2003-04-08 2015-05-29 Progenics Pharm Inc Preparaty farmaceutyczne zawierające metylonaltrekson
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
JP5469593B2 (ja) 2007-03-29 2014-04-16 ワイス・エルエルシー 末梢性オピオイド受容体アンタゴニストおよびその使用
WO2008121348A2 (en) * 2007-03-29 2008-10-09 Progenics Pharmaceuticals, Inc. Peripheral opioid receptor antagonists and uses thereof
MX2009010550A (es) 2007-03-29 2009-12-14 Progenics Pharm Inc Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas.
AU2008349873B2 (en) 2008-02-06 2014-02-13 Progenics Pharmaceuticals, Inc. Preparation and use of (R),(R)-2,2'-bis-methylnaltrexone
CA3108961C (en) * 2008-08-01 2024-07-02 Hospira, Inc. Pharmaceutical compositions comprising clevidipine and methods for producing low concentrations of impurities thereof
CN102186351A (zh) * 2008-08-01 2011-09-14 医药公司 药物组合物和用于稳定药物组合物的方法
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof
US9034389B2 (en) * 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
JP6081058B2 (ja) * 2009-03-19 2017-02-15 第一三共株式会社 包装により安定保存された固形製剤
CN101780036B (zh) * 2010-03-30 2011-11-16 武汉武药科技有限公司 丁酸氯维地平脂微球注射液及其制备方法
WO2012051116A1 (en) 2010-10-12 2012-04-19 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
US8658676B2 (en) * 2010-10-12 2014-02-25 The Medicines Company Clevidipine emulsion formulations containing antimicrobial agents
CN102531998A (zh) * 2010-12-09 2012-07-04 天津药物研究院 α型多晶型丁酸氯维地平结晶、其制备方法、用途和药物组合物
CN102525918A (zh) * 2010-12-30 2012-07-04 天津药物研究院 一种丁酸氯维地平的脂肪乳注射液及其制备工艺
US20120213855A1 (en) * 2011-02-17 2012-08-23 Cima Labs Inc. Dosage forms for weakly ionizable compounds
RU2623039C2 (ru) * 2011-04-01 2017-06-21 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Дигидропиридины (клевидипин) кратковременного действия для применения в восстановлении после инсульта
EP2793833B1 (en) 2011-12-20 2020-06-24 Vyome Therapeutics Limited Topical oil composition for the treatment of fungal infections
CN110840890A (zh) 2012-10-26 2020-02-28 凯西制药公司 用于在心力衰竭中控制血压和减轻呼吸困难的方法
CN103110580B (zh) * 2013-02-20 2014-09-17 北京德立福瑞医药科技有限公司 丁酸氯维地平注射剂
CN105263525A (zh) * 2013-04-12 2016-01-20 维奥姆生物科学有限公司 抗微生物剂的组合物和制剂、它们的方法以及用于治疗微生物感染的方法
MX385243B (es) 2014-05-19 2025-03-14 The Medicines Co Nanoparticulas de clevidipina y composiciones farmaceuticas que las contienen.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3315805A1 (de) * 1983-04-30 1984-11-08 Bayer Ag, 5090 Leverkusen Wirkstoffzubereitungen
DE3339236A1 (de) * 1983-10-28 1985-05-09 Bayer Ag Arzneimittelzubereitung
DE3515335C2 (de) * 1985-04-27 1995-01-26 Bayer Ag Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
DE4217842A1 (de) * 1992-05-29 1993-12-02 Dietl Hans Calciumantagonisten enthaltende pharmazeutische Zubereitung zur intravenösen und intrakoronaren Applikation sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
PL181462B1 (pl) 2001-07-31
HU9601268D0 (en) 1996-07-29
SE9303744D0 (sv) 1993-11-12
US5739152A (en) 1998-04-14
HU223142B1 (hu) 2004-03-29
JPH09505045A (ja) 1997-05-20
CZ133896A3 (en) 1996-09-11
FI961999A0 (fi) 1996-05-10
DE69429871T2 (de) 2002-08-22
UA40633C2 (uk) 2001-08-15
IL111345A0 (en) 1994-12-29
EP0727997B1 (en) 2002-02-13
MY121201A (en) 2006-01-28
CN1072934C (zh) 2001-10-17
IL111345A (en) 2000-08-31
CA2176360C (en) 2005-08-23
NO961898L (no) 1996-06-25
PL314263A1 (en) 1996-09-02
CN1136774A (zh) 1996-11-27
AU678650B2 (en) 1997-06-05
HUT74474A (en) 1996-12-30
DK0727997T3 (da) 2002-04-22
AU1037195A (en) 1995-05-29
JP3759951B2 (ja) 2006-03-29
DE69429871D1 (de) 2002-03-21
EG20764A (en) 2000-01-31
IS4224A (is) 1995-05-13
SK283271B6 (sk) 2003-04-01
SK59796A3 (en) 1996-12-04
WO1995013066A1 (en) 1995-05-18
ATE213158T1 (de) 2002-02-15
CA2176360A1 (en) 1995-05-18
NO961898D0 (no) 1996-05-10
ZA948180B (en) 1995-05-12
NZ276197A (en) 1997-04-24
HK1013261A1 (en) 1999-08-20
CZ290772B6 (cs) 2002-10-16
IS2036B (is) 2005-08-15
PT727997E (pt) 2002-07-31
NO314877B1 (no) 2003-06-10
ES2172572T3 (es) 2002-10-01
RU2144358C1 (ru) 2000-01-20
FI961999L (fi) 1996-05-10
FI116999B (fi) 2006-05-15
EP0727997A1 (en) 1996-08-28
SA94150314B1 (ar) 2005-06-14
KR100345627B1 (ko) 2003-03-15

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