EE200200425A - Selektiivsete PDE4 isosüümide inhibiitoritena kasulikud nikotiinamiidi bensokondenseerunud heterotsüklüülderivaadid - Google Patents
Selektiivsete PDE4 isosüümide inhibiitoritena kasulikud nikotiinamiidi bensokondenseerunud heterotsüklüülderivaadidInfo
- Publication number
- EE200200425A EE200200425A EEP200200425A EEP200200425A EE200200425A EE 200200425 A EE200200425 A EE 200200425A EE P200200425 A EEP200200425 A EE P200200425A EE P200200425 A EEP200200425 A EE P200200425A EE 200200425 A EE200200425 A EE 200200425A
- Authority
- EE
- Estonia
- Prior art keywords
- nicotinamide
- inhibitors
- useful
- selective pde4
- pde4 isozymes
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17928400P | 2000-01-31 | 2000-01-31 | |
| PCT/IB2001/000124 WO2001057036A1 (en) | 2000-01-31 | 2001-01-30 | Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of pde4 isozymes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EE200200425A true EE200200425A (et) | 2003-10-15 |
Family
ID=22655931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200200425A EE200200425A (et) | 2000-01-31 | 2001-01-30 | Selektiivsete PDE4 isosüümide inhibiitoritena kasulikud nikotiinamiidi bensokondenseerunud heterotsüklüülderivaadid |
Country Status (41)
| Country | Link |
|---|---|
| US (1) | US7354941B2 (cs) |
| EP (1) | EP1252158B1 (cs) |
| JP (1) | JP3917863B2 (cs) |
| KR (1) | KR20020072299A (cs) |
| CN (1) | CN1404481A (cs) |
| AP (1) | AP2002002589A0 (cs) |
| AR (1) | AR027337A1 (cs) |
| AT (1) | ATE293624T1 (cs) |
| AU (1) | AU2700201A (cs) |
| BG (1) | BG106852A (cs) |
| BR (1) | BR0107964A (cs) |
| CA (1) | CA2398182C (cs) |
| CO (1) | CO5261634A1 (cs) |
| CZ (1) | CZ20022410A3 (cs) |
| DE (1) | DE60110205T2 (cs) |
| EA (1) | EA004885B1 (cs) |
| EE (1) | EE200200425A (cs) |
| ES (1) | ES2238415T3 (cs) |
| GE (1) | GEP20043302B (cs) |
| GT (1) | GT200100022A (cs) |
| HN (1) | HN2001000019A (cs) |
| HU (1) | HUP0204262A2 (cs) |
| IL (1) | IL150641A0 (cs) |
| IS (1) | IS6421A (cs) |
| MA (1) | MA26870A1 (cs) |
| MX (1) | MXPA02007419A (cs) |
| NO (1) | NO20023613L (cs) |
| NZ (1) | NZ519547A (cs) |
| OA (1) | OA12169A (cs) |
| PA (1) | PA8511201A1 (cs) |
| PE (1) | PE20011058A1 (cs) |
| PL (1) | PL357995A1 (cs) |
| PT (1) | PT1252158E (cs) |
| PY (1) | PY0102109A (cs) |
| SK (1) | SK10142002A3 (cs) |
| SV (1) | SV2002000299A (cs) |
| TN (1) | TNSN01020A1 (cs) |
| TR (1) | TR200201880T2 (cs) |
| UY (1) | UY26569A1 (cs) |
| WO (1) | WO2001057036A1 (cs) |
| ZA (1) | ZA200206033B (cs) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69942009D1 (de) * | 1998-10-15 | 2010-03-25 | Imp Innovations Ltd | Verbindungen für die behandlung von gewichtsverlust |
| DE60110057T2 (de) * | 2000-01-28 | 2005-09-08 | Alza Corp., Mountain View | Liposomen enthaltend eine eingeschlossene verbindung in übersattigter lösung |
| IL154004A0 (en) | 2000-09-18 | 2003-07-31 | Du Pont | Pyridinyl amides and imides for use as fungicides |
| WO2002060875A1 (en) | 2001-01-31 | 2002-08-08 | Pfizer Products Inc. | Nicotinamide biaryl derivatives useful as inhibitors of pde4 isozymes |
| CZ20031903A3 (cs) | 2001-01-31 | 2004-07-14 | Pfizer Products Inc. | Amidové deriváty thiazolyl-, oxazolyl-, pyrrolyl- a imidazolyl karboxylových kyselin užitečné jako inhibitory isozymů PDE4 |
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| US4861891A (en) * | 1988-08-31 | 1989-08-29 | Pfizer Inc. | Antidepressant N-substituted nicotinamide compounds |
| TW429148B (en) * | 1995-10-27 | 2001-04-11 | Pfizer | Pharmaceutical agents for the treatment of acute and chronic inflammatory diseases |
| CA2285548C (en) | 1997-04-04 | 2006-07-11 | Pfizer Products Inc. | Nicotinamide derivatives |
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