EE200300342A - Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine - Google Patents

Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine

Info

Publication number: EE200300342A
Authority: EE; Estonia
Prior art keywords: inhibitors; preparation; methods; releasing factor; corticotropin releasing
Prior art date: 2001-01-26

Application number

EEP200300342A

Other languages

English (en)

Estonian (et)

Inventor

M. Dubowchik Gene

Han Xiaojun

M. Vrudhula Vivekananda

Zuev Dmitry

Dasgupta Bireshwar

A. Michne Jodi

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-26

Filing date

2002-01-11

Publication date

2003-12-15

2002-01-11 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2003-12-15 Publication of EE200300342A publication Critical patent/EE200300342A/xx

Links

102000012289 Corticotropin-Releasing Hormone Human genes 0.000 title 1
108010022152 Corticotropin-Releasing Hormone Proteins 0.000 title 1
239000000055 Corticotropin-Releasing Hormone Substances 0.000 title 1
125000002883 imidazolyl group Chemical group 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Addiction (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Immunology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Orthopedic Medicine & Surgery (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
Nutrition Science (AREA)
Obesity (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)

EEP200300342A 2001-01-26 2002-01-11 Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine EE200300342A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US26457001P	2001-01-26	2001-01-26
PCT/US2002/000841 WO2002058704A1 (en)	2001-01-26	2002-01-11	Imidazolyl derivatives as corticotropin releasing factor inhibitors

Publications (1)

Publication Number	Publication Date
EE200300342A true EE200300342A (et)	2003-12-15

Family

ID=23006646

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300342A EE200300342A (et)	2001-01-26	2002-01-11	Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine

Country Status (22)

Country	Link
US (5)	US6888004B2 (cs)
EP (1)	EP1359916A4 (cs)
JP (1)	JP2004531475A (cs)
KR (1)	KR20040034594A (cs)
CN (1)	CN1499972A (cs)
BG (1)	BG107999A (cs)
BR (1)	BR0206698A (cs)
CA (1)	CA2434558A1 (cs)
CZ (1)	CZ20032044A3 (cs)
EE (1)	EE200300342A (cs)
HR (1)	HRP20030675A2 (cs)
HU (1)	HUP0303721A2 (cs)
IL (1)	IL156813A0 (cs)
IS (1)	IS6889A (cs)
MX (1)	MXPA03006484A (cs)
NO (1)	NO20033350L (cs)
PE (1)	PE20020844A1 (cs)
PL (1)	PL368555A1 (cs)
RU (1)	RU2003126188A (cs)
SK (1)	SK9222003A3 (cs)
WO (1)	WO2002058704A1 (cs)
ZA (1)	ZA200305531B (cs)

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CN109970707A (zh) *	2012-02-07	2019-07-05	拜耳知识产权有限责任公司	取代的邻氨基苯甲酸衍生物的制备方法
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CN105384691B (zh) *	2015-10-26	2018-06-29	深圳大学	一种谷氨酰胺酰基环化酶抑制剂的制备方法及应用
WO2019022873A1 (en) *	2017-07-24	2019-01-31	University Of South Florida	NEW BIS-CYCLIC GUANIDINES USEFUL AS ANTIBACTERIAL AGENTS
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US6696441B1 (en) *	2000-08-11	2004-02-24	The Regents Of The University Of California	Inhibition of p53-induced stress response
JP2004509863A (ja) *	2000-09-21	2004-04-02	ブリストル−マイヤーズ　スクイブ　カンパニー	コルチコトロピン放出因子のインヒビターとしての置換アゾール誘導体
KR20040034594A (ko) *	2001-01-26	2004-04-28	브리스톨-마이어스스퀴브컴파니	코르티코트로핀 방출 인자 억제제로서의 이미다졸릴 유도체

2002
- 2002-01-11 KR KR10-2003-7009883A patent/KR20040034594A/ko not_active Withdrawn
- 2002-01-11 BR BR0206698-0A patent/BR0206698A/pt not_active IP Right Cessation
- 2002-01-11 PL PL02368555A patent/PL368555A1/xx unknown
- 2002-01-11 CN CNA028071352A patent/CN1499972A/zh active Pending
- 2002-01-11 US US10/044,183 patent/US6888004B2/en not_active Expired - Lifetime
- 2002-01-11 IL IL15681302A patent/IL156813A0/xx unknown
- 2002-01-11 SK SK922-2003A patent/SK9222003A3/sk unknown
- 2002-01-11 EP EP02705754A patent/EP1359916A4/en not_active Withdrawn
- 2002-01-11 JP JP2002559038A patent/JP2004531475A/ja active Pending
- 2002-01-11 WO PCT/US2002/000841 patent/WO2002058704A1/en not_active Ceased
- 2002-01-11 CA CA002434558A patent/CA2434558A1/en not_active Abandoned
- 2002-01-11 HR HR20030675A patent/HRP20030675A2/hr not_active Application Discontinuation
- 2002-01-11 CZ CZ20032044A patent/CZ20032044A3/cs unknown
- 2002-01-11 RU RU2003126188/04A patent/RU2003126188A/ru not_active Application Discontinuation
- 2002-01-11 EE EEP200300342A patent/EE200300342A/xx unknown
- 2002-01-11 MX MXPA03006484A patent/MXPA03006484A/es unknown
- 2002-01-11 HU HU0303721A patent/HUP0303721A2/hu unknown
- 2002-01-25 PE PE2002000063A patent/PE20020844A1/es not_active Application Discontinuation
2003
- 2003-07-17 ZA ZA200305531A patent/ZA200305531B/en unknown
- 2003-07-17 BG BG107999A patent/BG107999A/xx unknown
- 2003-07-24 IS IS6889A patent/IS6889A/is unknown
- 2003-07-25 NO NO20033350A patent/NO20033350L/no not_active Application Discontinuation
2004
- 2004-01-29 US US10/767,645 patent/US7211669B2/en not_active Expired - Lifetime
- 2004-02-04 US US10/772,027 patent/US7244746B2/en not_active Expired - Lifetime
- 2004-02-04 US US10/771,766 patent/US7238699B2/en not_active Expired - Lifetime
- 2004-02-04 US US10/771,661 patent/US7125990B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
RU2003126188A (ru)	2005-03-27
BR0206698A (pt)	2004-04-20
EP1359916A1 (en)	2003-11-12
US20040254382A1 (en)	2004-12-16
NO20033350D0 (no)	2003-07-25
IS6889A (is)	2003-07-24
US20040225130A1 (en)	2004-11-11
US20020183375A1 (en)	2002-12-05
CZ20032044A3 (cs)	2003-12-17
US7244746B2 (en)	2007-07-17
PL368555A1 (en)	2005-04-04
CN1499972A (zh)	2004-05-26
US20040235924A1 (en)	2004-11-25
HUP0303721A2 (hu)	2004-03-01
PE20020844A1 (es)	2002-09-27
NO20033350L (no)	2003-09-22
US6888004B2 (en)	2005-05-03
US20040225001A1 (en)	2004-11-11
WO2002058704A1 (en)	2002-08-01
US7211669B2 (en)	2007-05-01
SK9222003A3 (en)	2004-05-04
US7238699B2 (en)	2007-07-03
US7125990B2 (en)	2006-10-24
IL156813A0 (en)	2004-02-08
KR20040034594A (ko)	2004-04-28
MXPA03006484A (es)	2003-09-22
JP2004531475A (ja)	2004-10-14
ZA200305531B (en)	2004-07-27
CA2434558A1 (en)	2002-08-01
HRP20030675A2 (en)	2004-08-31
BG107999A (en)	2004-08-31
EP1359916A4 (en)	2004-04-07

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