EE200300342A - Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine - Google Patents

Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine

Info

Publication number: EE200300342A
Authority: EE; Estonia
Prior art keywords: inhibitors; preparation; methods; releasing factor; corticotropin releasing
Prior art date: 2001-01-26

Application number

EEP200300342A

Other languages

English (en)

Estonian (et)

Inventor

M. Dubowchik Gene

Han Xiaojun

M. Vrudhula Vivekananda

Zuev Dmitry

Dasgupta Bireshwar

A. Michne Jodi

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-01-26

Filing date

2002-01-11

Publication date

2003-12-15

2002-01-11 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2003-12-15 Publication of EE200300342A publication Critical patent/EE200300342A/xx

Links

102000012289 Corticotropin-Releasing Hormone Human genes 0.000 title 1
108010022152 Corticotropin-Releasing Hormone Proteins 0.000 title 1
239000000055 Corticotropin-Releasing Hormone Substances 0.000 title 1
125000002883 imidazolyl group Chemical group 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Cardiology (AREA)
Addiction (AREA)
Heart & Thoracic Surgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Immunology (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Pregnancy & Childbirth (AREA)
Gynecology & Obstetrics (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Obesity (AREA)
Nutrition Science (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Anesthesiology (AREA)

EEP200300342A 2001-01-26 2002-01-11 Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine EE200300342A (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US26457001P	2001-01-26	2001-01-26
PCT/US2002/000841 WO2002058704A1 (en)	2001-01-26	2002-01-11	Imidazolyl derivatives as corticotropin releasing factor inhibitors

Publications (1)

Publication Number	Publication Date
EE200300342A true EE200300342A (et)	2003-12-15

Family

ID=23006646

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EEP200300342A EE200300342A (et)	2001-01-26	2002-01-11	Imidasolüüli derivaadid kui kortikotropiini vabastava faktori inhibiitorid, nende saamismeetodid ning kasutamine

Country Status (22)

Country	Link
US (5)	US6888004B2 (cs)
EP (1)	EP1359916A4 (cs)
JP (1)	JP2004531475A (cs)
KR (1)	KR20040034594A (cs)
CN (1)	CN1499972A (cs)
BG (1)	BG107999A (cs)
BR (1)	BR0206698A (cs)
CA (1)	CA2434558A1 (cs)
CZ (1)	CZ20032044A3 (cs)
EE (1)	EE200300342A (cs)
HR (1)	HRP20030675A2 (cs)
HU (1)	HUP0303721A2 (cs)
IL (1)	IL156813A0 (cs)
IS (1)	IS6889A (cs)
MX (1)	MXPA03006484A (cs)
NO (1)	NO20033350L (cs)
PE (1)	PE20020844A1 (cs)
PL (1)	PL368555A1 (cs)
RU (1)	RU2003126188A (cs)
SK (1)	SK9222003A3 (cs)
WO (1)	WO2002058704A1 (cs)
ZA (1)	ZA200305531B (cs)

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JP6483610B2 (ja) *	2012-07-18	2019-03-13	ユニバーシティオブノートルダムデュラック	５，５−ヘテロ芳香族抗感染症化合物
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CN105384691B (zh) *	2015-10-26	2018-06-29	深圳大学	一种谷氨酰胺酰基环化酶抑制剂的制备方法及应用
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US6696441B1 (en) *	2000-08-11	2004-02-24	The Regents Of The University Of California	Inhibition of p53-induced stress response
WO2002024200A1 (en) *	2000-09-21	2002-03-28	Bristol-Myers Squibb Company	Substituted azole derivatives as inhibitors of corticotropin releasing factor
US6888004B2 (en) *	2001-01-26	2005-05-03	Bristol-Myers Squibb Company	Imidazolyl derivatives as corticotropin releasing factor inhibitors

2002
- 2002-01-11 US US10/044,183 patent/US6888004B2/en not_active Expired - Lifetime
- 2002-01-11 IL IL15681302A patent/IL156813A0/xx unknown
- 2002-01-11 KR KR10-2003-7009883A patent/KR20040034594A/ko not_active Withdrawn
- 2002-01-11 RU RU2003126188/04A patent/RU2003126188A/ru not_active Application Discontinuation
- 2002-01-11 EP EP02705754A patent/EP1359916A4/en not_active Withdrawn
- 2002-01-11 CZ CZ20032044A patent/CZ20032044A3/cs unknown
- 2002-01-11 WO PCT/US2002/000841 patent/WO2002058704A1/en not_active Ceased
- 2002-01-11 CA CA002434558A patent/CA2434558A1/en not_active Abandoned
- 2002-01-11 EE EEP200300342A patent/EE200300342A/xx unknown
- 2002-01-11 PL PL02368555A patent/PL368555A1/xx unknown
- 2002-01-11 JP JP2002559038A patent/JP2004531475A/ja active Pending
- 2002-01-11 BR BR0206698-0A patent/BR0206698A/pt not_active IP Right Cessation
- 2002-01-11 HU HU0303721A patent/HUP0303721A2/hu unknown
- 2002-01-11 MX MXPA03006484A patent/MXPA03006484A/es unknown
- 2002-01-11 CN CNA028071352A patent/CN1499972A/zh active Pending
- 2002-01-11 SK SK922-2003A patent/SK9222003A3/sk unknown
- 2002-01-11 HR HR20030675A patent/HRP20030675A2/hr not_active Application Discontinuation
- 2002-01-25 PE PE2002000063A patent/PE20020844A1/es not_active Application Discontinuation
2003
- 2003-07-17 ZA ZA200305531A patent/ZA200305531B/en unknown
- 2003-07-17 BG BG107999A patent/BG107999A/xx unknown
- 2003-07-24 IS IS6889A patent/IS6889A/is unknown
- 2003-07-25 NO NO20033350A patent/NO20033350L/no not_active Application Discontinuation
2004
- 2004-01-29 US US10/767,645 patent/US7211669B2/en not_active Expired - Lifetime
- 2004-02-04 US US10/771,661 patent/US7125990B2/en not_active Expired - Lifetime
- 2004-02-04 US US10/771,766 patent/US7238699B2/en not_active Expired - Lifetime
- 2004-02-04 US US10/772,027 patent/US7244746B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CN1499972A (zh)	2004-05-26
JP2004531475A (ja)	2004-10-14
IS6889A (is)	2003-07-24
PL368555A1 (en)	2005-04-04
ZA200305531B (en)	2004-07-27
MXPA03006484A (es)	2003-09-22
NO20033350D0 (no)	2003-07-25
PE20020844A1 (es)	2002-09-27
BR0206698A (pt)	2004-04-20
EP1359916A1 (en)	2003-11-12
HUP0303721A2 (hu)	2004-03-01
SK9222003A3 (en)	2004-05-04
US7211669B2 (en)	2007-05-01
US20040225001A1 (en)	2004-11-11
US20040254382A1 (en)	2004-12-16
US20020183375A1 (en)	2002-12-05
CZ20032044A3 (cs)	2003-12-17
EP1359916A4 (en)	2004-04-07
US20040235924A1 (en)	2004-11-25
CA2434558A1 (en)	2002-08-01
US7238699B2 (en)	2007-07-03
BG107999A (en)	2004-08-31
NO20033350L (no)	2003-09-22
US20040225130A1 (en)	2004-11-11
US6888004B2 (en)	2005-05-03
IL156813A0 (en)	2004-02-08
US7125990B2 (en)	2006-10-24
US7244746B2 (en)	2007-07-17
KR20040034594A (ko)	2004-04-28
WO2002058704A1 (en)	2002-08-01
RU2003126188A (ru)	2005-03-27
HRP20030675A2 (en)	2004-08-31

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