EP0594847A4 - Für menschlichen fk506-bindendes protein kodierende dns und deren expression. - Google Patents
Für menschlichen fk506-bindendes protein kodierende dns und deren expression.Info
- Publication number
- EP0594847A4 EP0594847A4 EP19910912352 EP91912352A EP0594847A4 EP 0594847 A4 EP0594847 A4 EP 0594847A4 EP 19910912352 EP19910912352 EP 19910912352 EP 91912352 A EP91912352 A EP 91912352A EP 0594847 A4 EP0594847 A4 EP 0594847A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- binding protein
- human
- dna
- expression
- dna encoding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP183238/90 | 1990-07-11 | ||
| JP18323890A JP2982908B2 (ja) | 1990-07-11 | 1990-07-11 | ヒトfk506結合蛋白質をコードするdna |
| PCT/JP1991/000931 WO1992001052A1 (fr) | 1990-07-11 | 1991-07-11 | Adn codant pour une proteine de liaison de fk506 humaine et expression de cet adn |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| EP0594847A4 true EP0594847A4 (de) | 1993-06-14 |
| EP0594847A1 EP0594847A1 (de) | 1994-05-04 |
| EP0594847B1 EP0594847B1 (de) | 1998-12-23 |
Family
ID=16132196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP91912352A Expired - Lifetime EP0594847B1 (de) | 1990-07-11 | 1991-07-11 | Für menschlichen fk506-bindendes protein kodierende dns und deren expression |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0594847B1 (de) |
| JP (1) | JP2982908B2 (de) |
| DE (1) | DE69130684T2 (de) |
| WO (1) | WO1992001052A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2688227A1 (fr) * | 1992-03-04 | 1993-09-10 | Inst Nat Sante Rech Med | Proteines formant des complexes avec des chaperones et leurs ligands, leurs fragments, leur obtention et leurs applications biologiques. |
| US6063625A (en) * | 1993-02-12 | 2000-05-16 | Board Of Trustees Of Leland S, Stanford, Jr. University | Regulated transcription of targeted genes and other biological events |
| US5869337A (en) * | 1993-02-12 | 1999-02-09 | President And Fellows Of Harvard College | Regulated transcription of targeted genes and other biological events |
| US5834266A (en) * | 1993-02-12 | 1998-11-10 | President & Fellows Of Harvard College | Regulated apoptosis |
| US5830462A (en) * | 1993-02-12 | 1998-11-03 | President & Fellows Of Harvard College | Regulated transcription of targeted genes and other biological events |
| US6972193B1 (en) | 1993-02-12 | 2005-12-06 | Board Of Trustees Of Leland Stanford Junior University | Regulated transcription of targeted genes and other biological events |
| US6891021B2 (en) | 1993-02-12 | 2005-05-10 | Board Of Trustees Of The Leland Stanford Junior University | Regulated apoptosis |
| US5457182A (en) * | 1994-02-15 | 1995-10-10 | Merck & Co., Inc. | FK-506 cytosolic binding protein, FKBP12.6 |
| JPH07250686A (ja) * | 1994-03-10 | 1995-10-03 | Otsuka Pharmaceut Co Ltd | Fk506結合蛋白遺伝子 |
| AU2103399A (en) * | 1998-01-09 | 1999-07-26 | Human Genome Sciences, Inc. | Human fk506 binding proteins |
| DE19907598A1 (de) * | 1999-02-22 | 2000-08-24 | Schulz Burkhard | DNA Sequenz kodierend ein FKBP ähnliches Protein, Plasmide, Bakterien, Hefen und Pflanzen enthaltend dieses Protein sowie Mutanten in Arabidopsis für dieses Gen, die in der Ausprägung der Pflanzenarchitektur, der Reaktion gegenüber Brassinosteroiden und ihren Verbindungen und durch Ethylen vermittelten Gravitropismus der Wurzel defekt sind |
| KR20020024377A (ko) * | 2000-09-25 | 2002-03-30 | 김재도 | Fkbp-12를 이용한 결석형성 억제방법 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0379342A2 (de) * | 1989-01-19 | 1990-07-25 | Merck & Co. Inc. | Protein aus dem Cytosol, das FK-506 binden kann |
| WO1991004321A1 (en) * | 1989-09-25 | 1991-04-04 | President And Fellows Of Harvard College | Receptor for fk-506 |
| EP0481673A2 (de) * | 1990-10-15 | 1992-04-22 | Merck & Co. Inc. | Genen, die kodieren für das menschliche FK-506 Bindungsprotein und für ein S. cerevisiae Homolog, FKB1, und ihre Expression |
-
1990
- 1990-07-11 JP JP18323890A patent/JP2982908B2/ja not_active Expired - Lifetime
-
1991
- 1991-07-11 EP EP91912352A patent/EP0594847B1/de not_active Expired - Lifetime
- 1991-07-11 DE DE69130684T patent/DE69130684T2/de not_active Expired - Lifetime
- 1991-07-11 WO PCT/JP1991/000931 patent/WO1992001052A1/ja not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0379342A2 (de) * | 1989-01-19 | 1990-07-25 | Merck & Co. Inc. | Protein aus dem Cytosol, das FK-506 binden kann |
| WO1991004321A1 (en) * | 1989-09-25 | 1991-04-04 | President And Fellows Of Harvard College | Receptor for fk-506 |
| EP0481673A2 (de) * | 1990-10-15 | 1992-04-22 | Merck & Co. Inc. | Genen, die kodieren für das menschliche FK-506 Bindungsprotein und für ein S. cerevisiae Homolog, FKB1, und ihre Expression |
Non-Patent Citations (2)
| Title |
|---|
| NATURE vol. 346, no. 6285, 16 August 1990, MACMILLAN JOURNALS LTD.,LONDON, UK; pages 671 - 674 R.F. STANDAERT ET AL. 'Molecular cloning and overexpression of the human FK506-binding protein FKBP' * |
| See also references of WO9201052A1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0594847B1 (de) | 1998-12-23 |
| JPH0471492A (ja) | 1992-03-06 |
| JP2982908B2 (ja) | 1999-11-29 |
| EP0594847A1 (de) | 1994-05-04 |
| WO1992001052A1 (fr) | 1992-01-23 |
| DE69130684D1 (de) | 1999-02-04 |
| DE69130684T2 (de) | 1999-07-29 |
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